BacMap

Definition	Acinetobacter sp. ADP1 chromosome, complete genome.
Accession	NC_005966
Length	3,598,621

Click here to switch to the map view.

The map label for this gene is dcaA [H]

Identifier: 50084848

GI number: 50084848

Start: 1698028

End: 1699182

Strand: Direct

Name: dcaA [H]

Synonym: ACIAD1693

Alternate gene names: 50084848

Gene position: 1698028-1699182 (Clockwise)

Preceding gene: 50084842

Following gene: 50084849

Centisome position: 47.19

GC content: 41.21

Gene sequence:

>1155_bases
ATGATTCGCGATGAAGGGATGTTGCAACAATTACTTTCGACAATACGAGATTTTGTAAAAAATGAATTGATTCCTCGAGA
GCATGAAGTTGCAGAAAAGGATTGTATTCCTGAAGATATTATTCAGCAAATGCGAGAACTAGGCCTATTTGGTTTAACCA
TTCCCGAAGAATACGGTGGACTTGGAATCACAATGGAAGAAGAGGTGAATGTCGCGTTTGAACTTGGTCAGACATCCCCA
GCATTTCGTTCATTGATTGGCACAAATAATGGCATTGGTTCAAGTGGTTTAATCATTGATGGAACTGAGGAGCAAAAACA
GAAATATTTGCCACGTTATGCCAGTGGAGAAATTATTGGTTCATTTTGCTTAACTGAACCAGAAGCGGGTTCAGATGCTG
CCTCTTTAAAAACGACAGCGGTAAAAGATGGTGATTTCTACATATTAAATGGAACCAAGCGTTTTATTACCAATGCACCG
CATGCAGCAACATTTACCGTAATGGCACGCACCAATCCAGCAATTAAAGGGGCAGGTGGAATTTCTGCTTTTTTGGTAGA
AGCCAATACACCAGGTATCACACTAGGCAAAATAGATCAGAAAATGGGACAAAAAGGCTCTCATACCTGTGATGTGATTT
TTGAAAATTGTCGAGTACCTGCATCTGCATTAATTGGTGGCGTTGAAGGCGTTGGTTTTAAAACAGCAATGAAAGTGCTG
GATAAAGGCCGTCTACATATTGGTGCATATAGTGTAGGTGTTGCAGAGCGTATGTTGAATGATGCACTACATTATGCTGT
CGAGCGTAAGCAGTTTGGTCAACCCATTGCAAATTTTCAATTGATTCAAGCCATGCTGGCAGACTCTAAAGCCGAAATTT
ATGCGGCTAAATGTATGGTTTTGGATGCAGCACGTCGCCGTGATGAAGGCCAAAATATTAGTACAGAAGCCTCATGTGCC
AAGATGTTTGCAACAGAAATGTGTGGTCGAGTCGCAGATCGCTGTGTGCAAATTCATGGTGGGGCAGGTTACATCAGTGA
ATATTCGATTGAGCGTTTTTATCGTGACGTGCGTTTATTCCGTCTTTATGAGGGTACGACCCAAGTTCAGCAAATTATTA
TTGCCAAAAATATGATTAAGGAAGTGACGTCCTAA

Upstream 100 bases:

>100_bases
ATCAAAATGAAGCAGAACAAGATTTTGTGAAATCTTGCAGTCTGGCTATTTTCTAAAATAGTAGATTGCTATAGCGAAAT
ATAGAGATGGGAGATCACGC

Downstream 100 bases:

>100_bases
AGCCTTATTTTACTTAACATGAGGCAGAGGATGCCTCATGCATATATTGTCTGAGGATATAGACATGACAACAGATTCAA
TTACAACAAGCCAGCCTAAT

Product: acyl-CoA dehydrogenase

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MIRDEGMLQQLLSTIRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGGLGITMEEEVNVAFELGQTSP
AFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIGSFCLTEPEAGSDAASLKTTAVKDGDFYILNGTKRFITNAP
HAATFTVMARTNPAIKGAGGISAFLVEANTPGITLGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVL
DKGRLHIGAYSVGVAERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMVLDAARRRDEGQNISTEASCA
KMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLFRLYEGTTQVQQIIIAKNMIKEVTS

Sequences:

>Translated_384_residues
MIRDEGMLQQLLSTIRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGGLGITMEEEVNVAFELGQTSP
AFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIGSFCLTEPEAGSDAASLKTTAVKDGDFYILNGTKRFITNAP
HAATFTVMARTNPAIKGAGGISAFLVEANTPGITLGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVL
DKGRLHIGAYSVGVAERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMVLDAARRRDEGQNISTEASCA
KMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLFRLYEGTTQVQQIIIAKNMIKEVTS
>Mature_384_residues
MIRDEGMLQQLLSTIRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGGLGITMEEEVNVAFELGQTSP
AFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIGSFCLTEPEAGSDAASLKTTAVKDGDFYILNGTKRFITNAP
HAATFTVMARTNPAIKGAGGISAFLVEANTPGITLGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVL
DKGRLHIGAYSVGVAERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMVLDAARRRDEGQNISTEASCA
KMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLFRLYEGTTQVQQIIIAKNMIKEVTS

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=376, Percent_Identity=38.563829787234, Blast_Score=278, Evalue=5e-75,
Organism=Homo sapiens, GI4501859, Length=378, Percent_Identity=36.5079365079365, Blast_Score=260, Evalue=1e-69,
Organism=Homo sapiens, GI4557231, Length=373, Percent_Identity=37.8016085790885, Blast_Score=255, Evalue=4e-68,
Organism=Homo sapiens, GI187960098, Length=373, Percent_Identity=37.8016085790885, Blast_Score=255, Evalue=5e-68,
Organism=Homo sapiens, GI76496475, Length=377, Percent_Identity=37.9310344827586, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI4557235, Length=377, Percent_Identity=37.9310344827586, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI21361497, Length=378, Percent_Identity=38.3597883597884, Blast_Score=252, Evalue=3e-67,
Organism=Homo sapiens, GI226958412, Length=371, Percent_Identity=35.3099730458221, Blast_Score=242, Evalue=4e-64,
Organism=Homo sapiens, GI7656849, Length=369, Percent_Identity=37.3983739837398, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI226958414, Length=340, Percent_Identity=36.4705882352941, Blast_Score=234, Evalue=9e-62,
Organism=Homo sapiens, GI4501857, Length=375, Percent_Identity=35.7333333333333, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI4503943, Length=368, Percent_Identity=32.6086956521739, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI7669494, Length=356, Percent_Identity=32.5842696629214, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI48976061, Length=397, Percent_Identity=28.9672544080605, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI211971008, Length=397, Percent_Identity=28.9672544080605, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI38505218, Length=394, Percent_Identity=28.4263959390863, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI156104864, Length=302, Percent_Identity=25.8278145695364, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI156104866, Length=302, Percent_Identity=25.8278145695364, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786223, Length=372, Percent_Identity=29.5698924731183, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI87081958, Length=376, Percent_Identity=32.1808510638298, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI87081702, Length=297, Percent_Identity=29.96632996633, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87082384, Length=281, Percent_Identity=26.6903914590747, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17508101, Length=366, Percent_Identity=40.1639344262295, Blast_Score=272, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17506239, Length=363, Percent_Identity=39.6694214876033, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI17570075, Length=375, Percent_Identity=38.9333333333333, Blast_Score=264, Evalue=8e-71,
Organism=Caenorhabditis elegans, GI17569725, Length=366, Percent_Identity=40.4371584699454, Blast_Score=263, Evalue=9e-71,
Organism=Caenorhabditis elegans, GI17534899, Length=367, Percent_Identity=38.4196185286104, Blast_Score=260, Evalue=9e-70,
Organism=Caenorhabditis elegans, GI71985184, Length=376, Percent_Identity=37.2340425531915, Blast_Score=240, Evalue=8e-64,
Organism=Caenorhabditis elegans, GI17538396, Length=376, Percent_Identity=34.8404255319149, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17533517, Length=377, Percent_Identity=33.6870026525199, Blast_Score=225, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI71990804, Length=322, Percent_Identity=38.1987577639752, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI71985192, Length=323, Percent_Identity=36.5325077399381, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=42.6724137931034, Blast_Score=184, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI17534353, Length=373, Percent_Identity=30.8310991957105, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI71982178, Length=271, Percent_Identity=33.9483394833948, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17551932, Length=383, Percent_Identity=27.6762402088773, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17505929, Length=340, Percent_Identity=29.1176470588235, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=34.4398340248963, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17562446, Length=397, Percent_Identity=29.7229219143577, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17531913, Length=178, Percent_Identity=30.8988764044944, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI86563381, Length=268, Percent_Identity=26.865671641791, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI86563383, Length=268, Percent_Identity=26.865671641791, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17540842, Length=421, Percent_Identity=25.1781472684086, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=38.8297872340425, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24660351, Length=380, Percent_Identity=38.9473684210526, Blast_Score=265, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24666513, Length=381, Percent_Identity=37.7952755905512, Blast_Score=255, Evalue=4e-68,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=36.6310160427808, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI281363737, Length=339, Percent_Identity=37.7581120943953, Blast_Score=231, Evalue=7e-61,
Organism=Drosophila melanogaster, GI21355753, Length=376, Percent_Identity=31.9148936170213, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI19920834, Length=365, Percent_Identity=31.5068493150685, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24652780, Length=352, Percent_Identity=23.8636363636364, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 41945; Mature: 41945

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRDEGMLQQLLSTIRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGG
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHCCCEEEECCHHHCC
LGITMEEEVNVAFELGQTSPAFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIG
CCEEECCCCCEEEEECCCCHHHHHHHCCCCCCCCCCEEEECCHHHHHHHCCCCCCCCHHH
SFCLTEPEAGSDAASLKTTAVKDGDFYILNGTKRFITNAPHAATFTVMARTNPAIKGAGG
HHHCCCCCCCCCHHHCEEEEEECCCEEEECCCHHHHCCCCCCEEEEEEEECCCCCCCCCC
ISAFLVEANTPGITLGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVL
CEEEEEECCCCCEEHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHH
DKGRLHIGAYSVGVAERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMV
HCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHH
LDAARRRDEGQNISTEASCAKMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLF
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHH
RLYEGTTQVQQIIIAKNMIKEVTS
HHHCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRDEGMLQQLLSTIRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGG
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHCCCEEEECCHHHCC
LGITMEEEVNVAFELGQTSPAFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIG
CCEEECCCCCEEEEECCCCHHHHHHHCCCCCCCCCCEEEECCHHHHHHHCCCCCCCCHHH
SFCLTEPEAGSDAASLKTTAVKDGDFYILNGTKRFITNAPHAATFTVMARTNPAIKGAGG
HHHCCCCCCCCCHHHCEEEEEECCCEEEECCCHHHHCCCCCCEEEEEEEECCCCCCCCCC
ISAFLVEANTPGITLGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVL
CEEEEEECCCCCEEHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHH
DKGRLHIGAYSVGVAERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMV
HCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHH
LDAARRRDEGQNISTEASCAKMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLF
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHH
RLYEGTTQVQQIIIAKNMIKEVTS
HHHCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]