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The map label for this gene is cidA1 [H]

Identifier: 50084831

GI number: 50084831

Start: 1680291

End: 1680719

Strand: Reverse

Name: cidA1 [H]

Synonym: ACIAD1674

Alternate gene names: 50084831

Gene position: 1680719-1680291 (Counterclockwise)

Preceding gene: 50084837

Following gene: 50084830

Centisome position: 46.7

GC content: 40.33

Gene sequence:

>429_bases
GTGTATCAGTCACGTGGTTTATATCTTGTCCAAATTGTTATTCAGATCGCATTACTTATGCTGTTTTGGTGGGTTGGCTC
TTTATTGCAACGCTGGCTAAACTTACCTATCTCAGCAGGTGTAGTCGGCTTATTTCTGGTCTTGATTGGCTTACTCAGTG
GTGTATTCAAGCTTCAATGGATCAAGACAGGATCTGATTTCATTTTGGGCGAACTGGTATTGTTCTTTATTCCGTGTGTC
GTCGGTCTTATGAATTACAAAACATTATTCATCACAGAAGGCTGGCAATTATTGAGTGCTGTCGTACTTGGGACAATCTG
TGTGATGGTGTTTACTGCCTATAGTGTTCATATATGTTTTAAGCTAGAAGCATGGCTTAAACGACATCATAGATCTGGCC
ATCAACAACGATCTGGAGTGAAATCATGA

Upstream 100 bases:

>100_bases
ATAAAAGAATAATTATAATTTTATTATTCATAATATGACATAAAAGTCGATCTAAAATACATTTATTCCCTATAAAATCA
CTCAGCTTAAAGGTGCTACC

Downstream 100 bases:

>100_bases
ATATTGCATTATTGTGGTTATTCGGAACGCTTATGGGTTATGTTATCGCCAAACCTATTTACCGTCGTTTACCGTATTTA
CCTTTTTCACCCGCTATTTT

Product: transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MYQSRGLYLVQIVIQIALLMLFWWVGSLLQRWLNLPISAGVVGLFLVLIGLLSGVFKLQWIKTGSDFILGELVLFFIPCV
VGLMNYKTLFITEGWQLLSAVVLGTICVMVFTAYSVHICFKLEAWLKRHHRSGHQQRSGVKS

Sequences:

>Translated_142_residues
MYQSRGLYLVQIVIQIALLMLFWWVGSLLQRWLNLPISAGVVGLFLVLIGLLSGVFKLQWIKTGSDFILGELVLFFIPCV
VGLMNYKTLFITEGWQLLSAVVLGTICVMVFTAYSVHICFKLEAWLKRHHRSGHQQRSGVKS
>Mature_142_residues
MYQSRGLYLVQIVIQIALLMLFWWVGSLLQRWLNLPISAGVVGLFLVLIGLLSGVFKLQWIKTGSDFILGELVLFFIPCV
VGLMNYKTLFITEGWQLLSAVVLGTICVMVFTAYSVHICFKLEAWLKRHHRSGHQQRSGVKS

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 16129; Mature: 16129

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQSRGLYLVQIVIQIALLMLFWWVGSLLQRWLNLPISAGVVGLFLVLIGLLSGVFKLQW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
IKTGSDFILGELVLFFIPCVVGLMNYKTLFITEGWQLLSAVVLGTICVMVFTAYSVHICF
HHCCCHHHHHHHHHHHHHHHHHHHCCHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
KLEAWLKRHHRSGHQQRSGVKS
HHHHHHHHHHHCCHHHHCCCCC
>Mature Secondary Structure
MYQSRGLYLVQIVIQIALLMLFWWVGSLLQRWLNLPISAGVVGLFLVLIGLLSGVFKLQW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
IKTGSDFILGELVLFFIPCVVGLMNYKTLFITEGWQLLSAVVLGTICVMVFTAYSVHICF
HHCCCHHHHHHHHHHHHHHHHHHHCCHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
KLEAWLKRHHRSGHQQRSGVKS
HHHHHHHHHHHCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]