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The map label for this gene is etfD

Identifier: 50084837

GI number: 50084837

Start: 1684094

End: 1685806

Strand: Reverse

Name: etfD

Synonym: ACIAD1680

Alternate gene names: 50084837

Gene position: 1685806-1684094 (Counterclockwise)

Preceding gene: 50084838

Following gene: 50084831

Centisome position: 46.85

GC content: 47.81

Gene sequence:

>1713_bases
ATGATAACGATTGAACGCGAAGCGATGGAGTTTGACGTAGTGATCGTTGGTGCTGGACCTGCCGGTCTATCTGCTGCGAT
TAAAATTCGCCAACTCGCGATTGAAAACAATTTACCTGATCTGTCCGTCTGCGTCGTCGAAAAAGGTTCCGAAGTAGGTG
CTCACATCCTCTCTGGTGCAGTGCTTGAACCTCGTGCCATCAATGAACTTTTCCCCAACTGGAAAGAAGAAGGTGCACCG
CTCAATGTCCCAGTGACTGAGGATAAAACCTATTTCCTGATGTCGGATGAGAAGTCTCAGGAAGCACCGCACTGGATGGT
GCCTAAAACCATGCACAATGATGGCAATTATGTCATCTCGCTGGGCAATGTGGTGCGCTGGTTAGGCCAGAAGGCGGAAG
AGCTTGAAGTCTCTATTTTTCCAGGCTTTGCTGCTGCCGAGATTCTGTATCATGCTGATGGTACGGTTAAGGGTATTCAG
ACGGGTGATATGGGTATTGGCAAGGATGGCGAACCAACGCATAACTTTGCGCCGGGTTATGAACTGCATGCCAAATATAC
GCTATTTGCCGAAGGTTGCCGTGGTCATTTAGGCAAGCGCCTGATCAATAAGTTTAATCTGGATCAGGATGCTGACCCGC
AGCATTACGGTATCGGGATTAAAGAGCTTTGGGAAATCGATCCTGCCAAGCATAAACCAGGTCTGGTGATGCATGGTTCT
GGCTGGCCATTGTCTGAAACGGGTTCTTCTGGTGGCTGGTGGTTATATCATGCCGAGAATAATCAGGTGACTCTGGGCAT
GATCGTGGATTTATCGTATGAAAATCCGCATATGTTCCCGTTTATGGAAATGCAGCGCTGGAAAACCCACCCACTGATCA
AACAGTATCTGGAAGGTGGTAAGCGTATTTCTTACGGTGCACGTGCTGTGGTCAAAGGTGGCTTAAACTCACTGCCCAAG
TTGACTTTCCCAGGTGGTTGTCTGATTGGTGATGATGCAGGCTTTTTGAACTTTGCGAAAATCAAAGGCTCACATACGGC
CATGAAATCTGGCATGCTTTGCGGTGAAGCCGTATTTGAAGCGATTGCACGTGGTGTCGACAAAGGCGGTGATCTAGCCA
TTGCCCGTGTCGTTGAAGGTGAAGATTTGTTTGATAAGGAGCTCACCACCTACACGCAGAAATTTGATAAGAGCTGGCTT
AAAGAAGAGTTACACCGCAGTCGTAATTTTGGTCCAGCCATGCACAAGTTTGGTTTATGGATTGGTGGTGCATTTAACTT
TGTGGATCAGAACATTTTTAAAGTTCCATTCACTCTGCACGATCTTCAGCCTGACTACAGCGCACTGAAAACTCAGGATC
AAGCCACCTTTAAACCAAACTATCCAAAGCCAGATGGCAAGCTGACGTTTGACCGTTTGTCTTCGGTATTTGTATCCAAT
ACGGTACATGAAGAAAATCAGCCATCACACTTGAAACTGACCGATGCCAGTATTCCTGTGGCGGTGAATCTACCAAGATG
GGATGAGCCAGCTCAGCGCTACTGCCCTGCGGGTGTGTACGAAATTGTGGATGAAGGTGAAGGCAACAAGCGTTTCCAGA
TCAATGCAGCCAACTGTGTACACTGCAAAACCTGTGATATCAAGGATCCATCTCAGAATATCACATGGGTGACGCCTGAA
GGCGGCGGCGGGCCGAATTACCCTAACATGTAA

Upstream 100 bases:

>100_bases
GCCAGTAATATACACACTGGCTTTTTAACATTAAATAATGGTTGTTTTAATATTTTTTTCAAATTAAAATATCGACAAGC
GAAACTAAATTTCTTTTATT

Downstream 100 bases:

>100_bases
TTCGTATCCGAATATATGATTTTGTATGTTATCTCAAAGTGCTGCCTTGCCATATCTTATATTTCAATGTGTAATTTTTA
AAAATGGCTATCAATTAAAA

Product: electron transfer flavoprotein-ubiquinone oxidoreductase

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MITIEREAMEFDVVIVGAGPAGLSAAIKIRQLAIENNLPDLSVCVVEKGSEVGAHILSGAVLEPRAINELFPNWKEEGAP
LNVPVTEDKTYFLMSDEKSQEAPHWMVPKTMHNDGNYVISLGNVVRWLGQKAEELEVSIFPGFAAAEILYHADGTVKGIQ
TGDMGIGKDGEPTHNFAPGYELHAKYTLFAEGCRGHLGKRLINKFNLDQDADPQHYGIGIKELWEIDPAKHKPGLVMHGS
GWPLSETGSSGGWWLYHAENNQVTLGMIVDLSYENPHMFPFMEMQRWKTHPLIKQYLEGGKRISYGARAVVKGGLNSLPK
LTFPGGCLIGDDAGFLNFAKIKGSHTAMKSGMLCGEAVFEAIARGVDKGGDLAIARVVEGEDLFDKELTTYTQKFDKSWL
KEELHRSRNFGPAMHKFGLWIGGAFNFVDQNIFKVPFTLHDLQPDYSALKTQDQATFKPNYPKPDGKLTFDRLSSVFVSN
TVHEENQPSHLKLTDASIPVAVNLPRWDEPAQRYCPAGVYEIVDEGEGNKRFQINAANCVHCKTCDIKDPSQNITWVTPE
GGGGPNYPNM

Sequences:

>Translated_570_residues
MITIEREAMEFDVVIVGAGPAGLSAAIKIRQLAIENNLPDLSVCVVEKGSEVGAHILSGAVLEPRAINELFPNWKEEGAP
LNVPVTEDKTYFLMSDEKSQEAPHWMVPKTMHNDGNYVISLGNVVRWLGQKAEELEVSIFPGFAAAEILYHADGTVKGIQ
TGDMGIGKDGEPTHNFAPGYELHAKYTLFAEGCRGHLGKRLINKFNLDQDADPQHYGIGIKELWEIDPAKHKPGLVMHGS
GWPLSETGSSGGWWLYHAENNQVTLGMIVDLSYENPHMFPFMEMQRWKTHPLIKQYLEGGKRISYGARAVVKGGLNSLPK
LTFPGGCLIGDDAGFLNFAKIKGSHTAMKSGMLCGEAVFEAIARGVDKGGDLAIARVVEGEDLFDKELTTYTQKFDKSWL
KEELHRSRNFGPAMHKFGLWIGGAFNFVDQNIFKVPFTLHDLQPDYSALKTQDQATFKPNYPKPDGKLTFDRLSSVFVSN
TVHEENQPSHLKLTDASIPVAVNLPRWDEPAQRYCPAGVYEIVDEGEGNKRFQINAANCVHCKTCDIKDPSQNITWVTPE
GGGGPNYPNM
>Mature_570_residues
MITIEREAMEFDVVIVGAGPAGLSAAIKIRQLAIENNLPDLSVCVVEKGSEVGAHILSGAVLEPRAINELFPNWKEEGAP
LNVPVTEDKTYFLMSDEKSQEAPHWMVPKTMHNDGNYVISLGNVVRWLGQKAEELEVSIFPGFAAAEILYHADGTVKGIQ
TGDMGIGKDGEPTHNFAPGYELHAKYTLFAEGCRGHLGKRLINKFNLDQDADPQHYGIGIKELWEIDPAKHKPGLVMHGS
GWPLSETGSSGGWWLYHAENNQVTLGMIVDLSYENPHMFPFMEMQRWKTHPLIKQYLEGGKRISYGARAVVKGGLNSLPK
LTFPGGCLIGDDAGFLNFAKIKGSHTAMKSGMLCGEAVFEAIARGVDKGGDLAIARVVEGEDLFDKELTTYTQKFDKSWL
KEELHRSRNFGPAMHKFGLWIGGAFNFVDQNIFKVPFTLHDLQPDYSALKTQDQATFKPNYPKPDGKLTFDRLSSVFVSN
TVHEENQPSHLKLTDASIPVAVNLPRWDEPAQRYCPAGVYEIVDEGEGNKRFQINAANCVHCKTCDIKDPSQNITWVTPE
GGGGPNYPNM

Specific function: Accepts electrons from ETF and reduces ubiquinone

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain

Homologues:

Organism=Homo sapiens, GI119703746, Length=575, Percent_Identity=51.4782608695652, Blast_Score=561, Evalue=1e-160,
Organism=Escherichia coli, GI1787991, Length=335, Percent_Identity=26.5671641791045, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786227, Length=335, Percent_Identity=25.9701492537313, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI87082155, Length=303, Percent_Identity=25.7425742574257, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25144720, Length=581, Percent_Identity=50.4302925989673, Blast_Score=550, Evalue=1e-157,
Organism=Saccharomyces cerevisiae, GI6324932, Length=578, Percent_Identity=42.3875432525952, Blast_Score=434, Evalue=1e-122,
Organism=Drosophila melanogaster, GI24652256, Length=577, Percent_Identity=50.9532062391681, Blast_Score=553, Evalue=1e-157,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ETFD_ACIAD (P94132)

Other databases:

- EMBL:   U87258
- EMBL:   CR543861
- RefSeq:   YP_046347.1
- ProteinModelPortal:   P94132
- SMR:   P94132
- STRING:   P94132
- GeneID:   2881144
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1680
- NMPDR:   fig|62977.3.peg.1609
- eggNOG:   COG0644
- HOGENOM:   HBG291987
- OMA:   NQNINWT
- PhylomeDB:   P94132
- ProtClustDB:   CLSK707356
- BioCyc:   ASP62977:ACIAD1680-MONOMER
- GO:   GO:0006810
- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042
- PRINTS:   PR00420

Pfam domain/function: PF05187 ETF_QO

EC number: =1.5.5.1

Molecular weight: Translated: 62996; Mature: 62996

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS51379 4FE4S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIEREAMEFDVVIVGAGPAGLSAAIKIRQLAIENNLPDLSVCVVEKGSEVGAHILSGA
CEEEECCCEEEEEEEEECCCCCCHHHHEEEEEHHHCCCCCEEEEEEECCCHHHHHHHCCC
VLEPRAINELFPNWKEEGAPLNVPVTEDKTYFLMSDEKSQEAPHWMVPKTMHNDGNYVIS
CCCCHHHHHHCCCHHHCCCEECCEECCCCEEEEEECCCCCCCCCCCCCCEEECCCCEEEE
LGNVVRWLGQKAEELEVSIFPGFAAAEILYHADGTVKGIQTGDMGIGKDGEPTHNFAPGY
HHHHHHHHCCCCHHEEEEEECCHHHEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCE
ELHAKYTLFAEGCRGHLGKRLINKFNLDQDADPQHYGIGIKELWEIDPAKHKPGLVMHGS
EEEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHCCCCCCCCCCEEEECC
GWPLSETGSSGGWWLYHAENNQVTLGMIVDLSYENPHMFPFMEMQRWKTHPLIKQYLEGG
CCCCCCCCCCCCEEEEEECCCEEEEEEEEEEECCCCCCCCHHHHHHCCCCHHHHHHHCCC
KRISYGARAVVKGGLNSLPKLTFPGGCLIGDDAGFLNFAKIKGSHTAMKSGMLCGEAVFE
CEECCCCHHHHHCCCCCCCCEECCCCEEEECCCCCEEEEEECCCHHHHHHCCHHHHHHHH
AIARGVDKGGDLAIARVVEGEDLFDKELTTYTQKFDKSWLKEELHRSRNFGPAMHKFGLW
HHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHE
IGGAFNFVDQNIFKVPFTLHDLQPDYSALKTQDQATFKPNYPKPDGKLTFDRLSSVFVSN
ECCCHHHHCCCEEECCEEEECCCCCHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHC
TVHEENQPSHLKLTDASIPVAVNLPRWDEPAQRYCPAGVYEIVDEGEGNKRFQINAANCV
CCCCCCCCCEEEEECCCCCEEEECCCCCCHHHHHCCCCHHHHHHCCCCCCEEEEECCCEE
HCKTCDIKDPSQNITWVTPEGGGGPNYPNM
EEEECCCCCCCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MITIEREAMEFDVVIVGAGPAGLSAAIKIRQLAIENNLPDLSVCVVEKGSEVGAHILSGA
CEEEECCCEEEEEEEEECCCCCCHHHHEEEEEHHHCCCCCEEEEEEECCCHHHHHHHCCC
VLEPRAINELFPNWKEEGAPLNVPVTEDKTYFLMSDEKSQEAPHWMVPKTMHNDGNYVIS
CCCCHHHHHHCCCHHHCCCEECCEECCCCEEEEEECCCCCCCCCCCCCCEEECCCCEEEE
LGNVVRWLGQKAEELEVSIFPGFAAAEILYHADGTVKGIQTGDMGIGKDGEPTHNFAPGY
HHHHHHHHCCCCHHEEEEEECCHHHEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCE
ELHAKYTLFAEGCRGHLGKRLINKFNLDQDADPQHYGIGIKELWEIDPAKHKPGLVMHGS
EEEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHCCCCCCCCCCEEEECC
GWPLSETGSSGGWWLYHAENNQVTLGMIVDLSYENPHMFPFMEMQRWKTHPLIKQYLEGG
CCCCCCCCCCCCEEEEEECCCEEEEEEEEEEECCCCCCCCHHHHHHCCCCHHHHHHHCCC
KRISYGARAVVKGGLNSLPKLTFPGGCLIGDDAGFLNFAKIKGSHTAMKSGMLCGEAVFE
CEECCCCHHHHHCCCCCCCCEECCCCEEEECCCCCEEEEEECCCHHHHHHCCHHHHHHHH
AIARGVDKGGDLAIARVVEGEDLFDKELTTYTQKFDKSWLKEELHRSRNFGPAMHKFGLW
HHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHE
IGGAFNFVDQNIFKVPFTLHDLQPDYSALKTQDQATFKPNYPKPDGKLTFDRLSSVFVSN
ECCCHHHHCCCEEECCEEEECCCCCHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHC
TVHEENQPSHLKLTDASIPVAVNLPRWDEPAQRYCPAGVYEIVDEGEGNKRFQINAANCV
CCCCCCCCCEEEEECCCCCEEEECCCCCCHHHHHCCCCHHHHHHCCCCCCEEEEECCCEE
HCKTCDIKDPSQNITWVTPEGGGGPNYPNM
EEEECCCCCCCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9294455