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The map label for this gene is acsA [H]

Identifier: 50084767

GI number: 50084767

Start: 1602316

End: 1603959

Strand: Direct

Name: acsA [H]

Synonym: ACIAD1606

Alternate gene names: 50084767

Gene position: 1602316-1603959 (Clockwise)

Preceding gene: 50084766

Following gene: 50084768

Centisome position: 44.53

GC content: 41.97

Gene sequence:

>1644_bases
ATGTTGGATTATCAAACGGTCGCAACCTCATTTGACTTTCATAGAGCAGCAAATGAAATGTTATCTGGTTCACTGGATCA
AGTTAATGCATGTTACGAATGTTGTGATCGACATGCAGAATCAAACCCCGAAAAAATAGCATTATATTGGCAAGGCAAAG
ATGGTCGTCAATATCAATATACGTTTGCACAATTACAAAAGTGGTCCAGTCAATTTGCCAATTTTTTAAAATCACAAGGG
GTTCAAACAGGCGATCGTATTTCAGGTTTATTACCCAGAACACCTGAATTATTGGTGGTGATTTTAGGTGCTTGGCGAAT
TGGTGCAGTTTATCAGCCACTTTTTACGGCATTTGGCCCGAAAGCGATTGAGCATCGCGTGCAGCTTGCAAAAAGTAAAT
TGGTTGTGACTGATTTGGGTAATCGGAGCAAGCTTGATGAAGTAGCGCATTGTCCACCCATCATGACGGTTATTGGCGAA
AAAGATCATGCAGTAAATGATCAAGACTTAAATTTTTGGAAGCAAGTGAGTCAAGCGTCTGACCACTGTGATTTGGTTTT
ACAAGACATTCAAAAACCATTTTTACTGATGTTTACGTCGGGAACCACAGGCCCTGCAAAGCCTTTGGAAGTGCCTTTAA
AGGCATTAATCGCGTTTGGTCATTATATGAAAGATGCCATTGGTTTACGCACCGATGATGTCTTTTGGAATCTTGCAGAT
CCTGGCTGGGCATATGGTTTATATTATGCCATAACCGGGCCACTGCTTTTGGGGCATGCAACCTTATTTTATGAGGGTGG
TTTTAGTATCGATAGTTTGTGCCAAATTATTGAGGATTATAAAATTACCAATTTGGCAGGTGCACCGACTGCATACCGCA
TGATGATGGCAGCAGATCCAGCGAAAATCGCCTGCCTAAAGGGTAAATTACGTGTGATAAGTAGTGCAGGTGAACCACTC
AATCCAGAAGTATTTCGTTGGTTTAAACACACTTTAGATGCCCCTATTTTTGATCATTATGGTCAGACTGAAGTGGGTAT
GGTGGTATGTAATCATCACGGTTTAAGCCATGATGTGCGTGCAGGAACAGCAGGTTTTGCAAGTCCAGGCTATCGTGTGG
CCGTAGTGGATGAGCAGGGCAATGAACTTCCAGCGGATACGGCTGGAATATTGGCCGTCGATATTCAAAAGTCGCCGATG
ATGTGGTTTGGTGGTTATCAAGAAAGTCGAAAATCTCCTTTTTTAAAGCATTATTACTTAACAGGTGATACAGCCGAATT
ACATGCGGATGGCAGTATGAGTTTTGTAGGGCGTAGTGATGATGTCATCACCACATCAGGCTATCGTATTGGTCCTTTCG
ATGTTGAAAGTGCATTAATTGAACATCAAGCTGTAATTGAAGCAGCAGTTATTGGTGTGCCTGACCCAGAAAGAACGGAA
ATTGTAAAAGCATTTGTGATTTTGACAGCACAGACGAGCCCATCAGAGCAATTGGCCGAGGAACTACGCCAATTTGTTAA
AAAGCGTTTATCGGCACATGCTTATCCAAGACAAGTTGAGTTTGTGACAGAGTTGCCTAAAACTCCAAGTGGTAAGATTC
AACGGTTTTTGTTGCGTAATCAAGAGATTGCCAAGCAATCCTAA

Upstream 100 bases:

>100_bases
TTTACCGCAAAATTCGCAATAAAATCAGGCGAAGAAAAGCAATTAAACAGTAGAAATTTCGATTCAAAAATAACAATACA
TCTAGGATGGAGTATCTGAT

Downstream 100 bases:

>100_bases
TCAATTCAACCTAAAAAATGATTGCTTAAAATAAGCAGTTTTGCTTAATGCATTGTATAAAAATGAGCCAAGGAATGTGA
AATGCAATTTAATGAAGAAC

Product: acetyl-CoA synthetase/AMP-(fatty) acid ligase

Products: NA

Alternate protein names: Acetate--CoA ligase; Acetyl-CoA synthase; Acyl-activating enzyme [H]

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MLDYQTVATSFDFHRAANEMLSGSLDQVNACYECCDRHAESNPEKIALYWQGKDGRQYQYTFAQLQKWSSQFANFLKSQG
VQTGDRISGLLPRTPELLVVILGAWRIGAVYQPLFTAFGPKAIEHRVQLAKSKLVVTDLGNRSKLDEVAHCPPIMTVIGE
KDHAVNDQDLNFWKQVSQASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKALIAFGHYMKDAIGLRTDDVFWNLAD
PGWAYGLYYAITGPLLLGHATLFYEGGFSIDSLCQIIEDYKITNLAGAPTAYRMMMAADPAKIACLKGKLRVISSAGEPL
NPEVFRWFKHTLDAPIFDHYGQTEVGMVVCNHHGLSHDVRAGTAGFASPGYRVAVVDEQGNELPADTAGILAVDIQKSPM
MWFGGYQESRKSPFLKHYYLTGDTAELHADGSMSFVGRSDDVITTSGYRIGPFDVESALIEHQAVIEAAVIGVPDPERTE
IVKAFVILTAQTSPSEQLAEELRQFVKKRLSAHAYPRQVEFVTELPKTPSGKIQRFLLRNQEIAKQS

Sequences:

>Translated_547_residues
MLDYQTVATSFDFHRAANEMLSGSLDQVNACYECCDRHAESNPEKIALYWQGKDGRQYQYTFAQLQKWSSQFANFLKSQG
VQTGDRISGLLPRTPELLVVILGAWRIGAVYQPLFTAFGPKAIEHRVQLAKSKLVVTDLGNRSKLDEVAHCPPIMTVIGE
KDHAVNDQDLNFWKQVSQASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKALIAFGHYMKDAIGLRTDDVFWNLAD
PGWAYGLYYAITGPLLLGHATLFYEGGFSIDSLCQIIEDYKITNLAGAPTAYRMMMAADPAKIACLKGKLRVISSAGEPL
NPEVFRWFKHTLDAPIFDHYGQTEVGMVVCNHHGLSHDVRAGTAGFASPGYRVAVVDEQGNELPADTAGILAVDIQKSPM
MWFGGYQESRKSPFLKHYYLTGDTAELHADGSMSFVGRSDDVITTSGYRIGPFDVESALIEHQAVIEAAVIGVPDPERTE
IVKAFVILTAQTSPSEQLAEELRQFVKKRLSAHAYPRQVEFVTELPKTPSGKIQRFLLRNQEIAKQS
>Mature_547_residues
MLDYQTVATSFDFHRAANEMLSGSLDQVNACYECCDRHAESNPEKIALYWQGKDGRQYQYTFAQLQKWSSQFANFLKSQG
VQTGDRISGLLPRTPELLVVILGAWRIGAVYQPLFTAFGPKAIEHRVQLAKSKLVVTDLGNRSKLDEVAHCPPIMTVIGE
KDHAVNDQDLNFWKQVSQASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKALIAFGHYMKDAIGLRTDDVFWNLAD
PGWAYGLYYAITGPLLLGHATLFYEGGFSIDSLCQIIEDYKITNLAGAPTAYRMMMAADPAKIACLKGKLRVISSAGEPL
NPEVFRWFKHTLDAPIFDHYGQTEVGMVVCNHHGLSHDVRAGTAGFASPGYRVAVVDEQGNELPADTAGILAVDIQKSPM
MWFGGYQESRKSPFLKHYYLTGDTAELHADGSMSFVGRSDDVITTSGYRIGPFDVESALIEHQAVIEAAVIGVPDPERTE
IVKAFVILTAQTSPSEQLAEELRQFVKKRLSAHAYPRQVEFVTELPKTPSGKIQRFLLRNQEIAKQS

Specific function: Has a role in growth and sporulation on acetate [H]

COG id: COG0365

COG function: function code I; Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI38505220, Length=521, Percent_Identity=35.5086372360845, Blast_Score=291, Evalue=1e-78,
Organism=Homo sapiens, GI122937307, Length=515, Percent_Identity=35.7281553398058, Blast_Score=290, Evalue=2e-78,
Organism=Homo sapiens, GI115511026, Length=521, Percent_Identity=33.9731285988484, Blast_Score=280, Evalue=3e-75,
Organism=Homo sapiens, GI58082049, Length=507, Percent_Identity=35.1084812623274, Blast_Score=279, Evalue=6e-75,
Organism=Homo sapiens, GI157311624, Length=513, Percent_Identity=35.4775828460039, Blast_Score=278, Evalue=1e-74,
Organism=Homo sapiens, GI157311622, Length=513, Percent_Identity=35.4775828460039, Blast_Score=278, Evalue=1e-74,
Organism=Homo sapiens, GI42544132, Length=520, Percent_Identity=34.0384615384615, Blast_Score=272, Evalue=6e-73,
Organism=Homo sapiens, GI8923896, Length=569, Percent_Identity=30.4042179261863, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI253970489, Length=588, Percent_Identity=30.7823129251701, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI28416953, Length=545, Percent_Identity=29.1743119266055, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI13375727, Length=548, Percent_Identity=28.2846715328467, Blast_Score=215, Evalue=8e-56,
Organism=Homo sapiens, GI42544134, Length=351, Percent_Identity=27.9202279202279, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI195947378, Length=412, Percent_Identity=25.7281553398058, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI156151445, Length=579, Percent_Identity=23.8341968911917, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI187761345, Length=387, Percent_Identity=26.3565891472868, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI187761343, Length=387, Percent_Identity=26.3565891472868, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI1790505, Length=542, Percent_Identity=31.7343173431734, Blast_Score=268, Evalue=5e-73,
Organism=Escherichia coli, GI1786529, Length=546, Percent_Identity=29.3040293040293, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI145693145, Length=516, Percent_Identity=25.7751937984496, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1788107, Length=527, Percent_Identity=25.9962049335863, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI221142682, Length=524, Percent_Identity=22.7099236641221, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1786801, Length=455, Percent_Identity=23.2967032967033, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786810, Length=308, Percent_Identity=25.6493506493506, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71983001, Length=601, Percent_Identity=27.7870216306156, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI71982997, Length=601, Percent_Identity=27.7870216306156, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17558820, Length=490, Percent_Identity=24.6938775510204, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32563687, Length=514, Percent_Identity=24.3190661478599, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17557194, Length=536, Percent_Identity=25.3731343283582, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17538037, Length=536, Percent_Identity=24.8134328358209, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17559526, Length=556, Percent_Identity=25, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71994703, Length=532, Percent_Identity=22.1804511278195, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994694, Length=532, Percent_Identity=22.1804511278195, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71994690, Length=532, Percent_Identity=22.1804511278195, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17560308, Length=364, Percent_Identity=25, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17531443, Length=532, Percent_Identity=21.0526315789474, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560140, Length=498, Percent_Identity=22.8915662650602, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71985884, Length=362, Percent_Identity=27.9005524861878, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71996755, Length=494, Percent_Identity=22.6720647773279, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319264, Length=556, Percent_Identity=32.7338129496403, Blast_Score=239, Evalue=7e-64,
Organism=Saccharomyces cerevisiae, GI6323182, Length=568, Percent_Identity=30.4577464788732, Blast_Score=220, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6319699, Length=241, Percent_Identity=28.6307053941909, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24667955, Length=558, Percent_Identity=29.5698924731183, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI62472339, Length=530, Percent_Identity=29.0566037735849, Blast_Score=218, Evalue=9e-57,
Organism=Drosophila melanogaster, GI24667959, Length=493, Percent_Identity=28.8032454361055, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI21355225, Length=563, Percent_Identity=25.3996447602131, Blast_Score=168, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24581924, Length=519, Percent_Identity=25.0481695568401, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21356947, Length=511, Percent_Identity=24.0704500978474, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI19922652, Length=493, Percent_Identity=24.3407707910751, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21355181, Length=501, Percent_Identity=24.750499001996, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI18859661, Length=521, Percent_Identity=25.3358925143954, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24653035, Length=491, Percent_Identity=20.9775967413442, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24648260, Length=490, Percent_Identity=23.0612244897959, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24656500, Length=498, Percent_Identity=23.0923694779116, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI161076582, Length=503, Percent_Identity=21.272365805169, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI20130357, Length=499, Percent_Identity=22.4448897795591, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24648253, Length=492, Percent_Identity=21.3414634146341, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356441, Length=507, Percent_Identity=21.6962524654832, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648255, Length=492, Percent_Identity=21.5447154471545, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281365686, Length=462, Percent_Identity=21.8614718614719, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21358303, Length=457, Percent_Identity=19.2560175054705, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24583465, Length=563, Percent_Identity=21.4920071047957, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583463, Length=563, Percent_Identity=21.4920071047957, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281364798, Length=563, Percent_Identity=21.4920071047957, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648257, Length=546, Percent_Identity=22.1611721611722, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.1 [H]

Molecular weight: Translated: 60671; Mature: 60671

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDYQTVATSFDFHRAANEMLSGSLDQVNACYECCDRHAESNPEKIALYWQGKDGRQYQY
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEHH
TFAQLQKWSSQFANFLKSQGVQTGDRISGLLPRTPELLVVILGAWRIGAVYQPLFTAFGP
HHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
KAIEHRVQLAKSKLVVTDLGNRSKLDEVAHCPPIMTVIGEKDHAVNDQDLNFWKQVSQAS
HHHHHHHHHHHCCEEEEECCCCCHHHHHHCCCCHHEEECCCCCCCCCCHHHHHHHHHHCC
DHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKALIAFGHYMKDAIGLRTDDVFWNLAD
HHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
PGWAYGLYYAITGPLLLGHATLFYEGGFSIDSLCQIIEDYKITNLAGAPTAYRMMMAADP
CCHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHCCEECCCCCCHHHHHHHHCCC
AKIACLKGKLRVISSAGEPLNPEVFRWFKHTLDAPIFDHYGQTEVGMVVCNHHGLSHDVR
HHEEEECCCHHEEECCCCCCCHHHHHHHHHHHCCCHHHCCCCCEEEEEEECCCCCCCCCC
AGTAGFASPGYRVAVVDEQGNELPADTAGILAVDIQKSPMMWFGGYQESRKSPFLKHYYL
CCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCEEECCCCHHCCCCCEEEEEE
TGDTAELHADGSMSFVGRSDDVITTSGYRIGPFDVESALIEHQAVIEAAVIGVPDPERTE
CCCCEEEECCCCEEEECCCCCEEEECCEEECCCHHHHHHHHHHHHHHHHEECCCCCHHHH
IVKAFVILTAQTSPSEQLAEELRQFVKKRLSAHAYPRQVEFVTELPKTPSGKIQRFLLRN
HHEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHC
QEIAKQS
HHHHCCC
>Mature Secondary Structure
MLDYQTVATSFDFHRAANEMLSGSLDQVNACYECCDRHAESNPEKIALYWQGKDGRQYQY
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEHH
TFAQLQKWSSQFANFLKSQGVQTGDRISGLLPRTPELLVVILGAWRIGAVYQPLFTAFGP
HHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
KAIEHRVQLAKSKLVVTDLGNRSKLDEVAHCPPIMTVIGEKDHAVNDQDLNFWKQVSQAS
HHHHHHHHHHHCCEEEEECCCCCHHHHHHCCCCHHEEECCCCCCCCCCHHHHHHHHHHCC
DHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKALIAFGHYMKDAIGLRTDDVFWNLAD
HHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
PGWAYGLYYAITGPLLLGHATLFYEGGFSIDSLCQIIEDYKITNLAGAPTAYRMMMAADP
CCHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHCCEECCCCCCHHHHHHHHCCC
AKIACLKGKLRVISSAGEPLNPEVFRWFKHTLDAPIFDHYGQTEVGMVVCNHHGLSHDVR
HHEEEECCCHHEEECCCCCCCHHHHHHHHHHHCCCHHHCCCCCEEEEEEECCCCCCCCCC
AGTAGFASPGYRVAVVDEQGNELPADTAGILAVDIQKSPMMWFGGYQESRKSPFLKHYYL
CCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCEEECCCCHHCCCCCEEEEEE
TGDTAELHADGSMSFVGRSDDVITTSGYRIGPFDVESALIEHQAVIEAAVIGVPDPERTE
CCCCEEEECCCCEEEECCCCCEEEECCEEECCCHHHHHHHHHHHHHHHHEECCCCCHHHH
IVKAFVILTAQTSPSEQLAEELRQFVKKRLSAHAYPRQVEFVTELPKTPSGKIQRFLLRN
HHEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHC
QEIAKQS
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]