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The map label for this gene is acdA [H]

Identifier: 50084590

GI number: 50084590

Start: 1407253

End: 1408557

Strand: Reverse

Name: acdA [H]

Synonym: ACIAD1413

Alternate gene names: 50084590

Gene position: 1408557-1407253 (Counterclockwise)

Preceding gene: 50084591

Following gene: 50084589

Centisome position: 39.14

GC content: 40.38

Gene sequence:

>1305_bases
ATGGAGTTTGCAATGTCAGATATGATCAATAAGGCTCAGGGATTTGGACTCTCCTTGATCACAAAAATAGCTGGAAGCGA
TGTGCTTGATCAGCTTAAATTAAGAAAGTTTTTAGAAAAATCACTTTATCAGGGTTCCAAAAGTGGCTTTAAAGCCATTT
CAACAGCACAAAAAACCTTTAAAACCAGTTCCATTGATCATCAGCGTCTACCAAAGCAGAATAAATCAATTTTTGATCTC
AGTCTGACTGAAGAACAGACCATGACACGCGAAGCAATGTCCAGATTTGCCCAGGATGTTCTCATGCAAATAGCACATGA
TGCAGATCATCATGCTCGATTTCCAGAAGAACTGTGGCAATATCTTGAAGACTTAGGATTAAATTATTATGCTTTGCCTG
AATCATTAGGTGGTGTAGCCAGTGAACAAAATATAGTAAGCAATATATTAATTGCAGAAGATTTAGCTCAAGGAGATTTT
AGTCTGAGCGCTGGATTACTTAGCACATTTAGTGTGATTAATGCATTAACTCGTTGGGGATCCGAAAGTACACAATCGAA
ATATTTAACCGCTTTTTCGGAAGATCCAAATCTTAAAGCAACTTTTGCAACACAGGAAAACACACCTGCGTTTAATCCGT
TTAAACTTAAGACACAAGCTACATTACAAAATAATCACTATTTCTTATCTGGTGAAAAAACTCTGGTCATTTTAGGCGAG
AGTGCAGATCTAATTTTGGTTACCGCCATGTTGGATGGACAACCAGAAGTATTTATCGTAGAGCGCGATCCAACCATTTC
TATAAAATCCGCTCCTGCCATGGGATTAAAAGCAGCGCAAACCATGAGTCTTTATTTTGATCATACCCCAGCGGTGTTAT
TAGGTGACAACGATTTTGATTACAGTGCGTTTATCGATTTAGGCTCATTGATGTGGTGTGCAATGGCTGTAGGTACCTGT
GAAGCGGTTAAAAGTTATTGTATTGCCTATGCAAATGACCGAACAGCGTTTGGTGAACCAATCTCACATCGTCAAAGTGT
TGCTTTTATGATTGCAGATATGGCGATCGAAATCGATGCTATGCGAATGCTGATCTGGAATGCAGCGAGCCTTGCAGAAG
CTGGTCAAGCGTTTCATCGGGAAGCTTATTTGGCTCGCTTACTCTGTGCTGAGAAATCCATGCGAATCGGAACCGATGGC
GTACAGCTACTTGGTGGACACGGATTTACCAAAGAGCATCCTGTCGAGCGTTGGTATCGGGATTTACGTGCAACTGCTAT
TTTGCATTCAGGTTTACATGCTTAA

Upstream 100 bases:

>100_bases
TAAAGTCTATCACCACTTATCGCTTTTTCTCGTCTTGTCAATCTTGACATAGTTTTTCCAAATTCCTCATGTCAGCATAC
ATTGCATTACCCGACAATCA

Downstream 100 bases:

>100_bases
GTATTGATTAAAATAACTCCAAGGATTAGCCATGAATTTACAAGACCCTAAAAAATTTAAAATGATGGTCAACCAAGCCC
ATGATGTCGCACTCAATGTT

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MEFAMSDMINKAQGFGLSLITKIAGSDVLDQLKLRKFLEKSLYQGSKSGFKAISTAQKTFKTSSIDHQRLPKQNKSIFDL
SLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQYLEDLGLNYYALPESLGGVASEQNIVSNILIAEDLAQGDF
SLSAGLLSTFSVINALTRWGSESTQSKYLTAFSEDPNLKATFATQENTPAFNPFKLKTQATLQNNHYFLSGEKTLVILGE
SADLILVTAMLDGQPEVFIVERDPTISIKSAPAMGLKAAQTMSLYFDHTPAVLLGDNDFDYSAFIDLGSLMWCAMAVGTC
EAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDAMRMLIWNAASLAEAGQAFHREAYLARLLCAEKSMRIGTDG
VQLLGGHGFTKEHPVERWYRDLRATAILHSGLHA

Sequences:

>Translated_434_residues
MEFAMSDMINKAQGFGLSLITKIAGSDVLDQLKLRKFLEKSLYQGSKSGFKAISTAQKTFKTSSIDHQRLPKQNKSIFDL
SLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQYLEDLGLNYYALPESLGGVASEQNIVSNILIAEDLAQGDF
SLSAGLLSTFSVINALTRWGSESTQSKYLTAFSEDPNLKATFATQENTPAFNPFKLKTQATLQNNHYFLSGEKTLVILGE
SADLILVTAMLDGQPEVFIVERDPTISIKSAPAMGLKAAQTMSLYFDHTPAVLLGDNDFDYSAFIDLGSLMWCAMAVGTC
EAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDAMRMLIWNAASLAEAGQAFHREAYLARLLCAEKSMRIGTDG
VQLLGGHGFTKEHPVERWYRDLRATAILHSGLHA
>Mature_434_residues
MEFAMSDMINKAQGFGLSLITKIAGSDVLDQLKLRKFLEKSLYQGSKSGFKAISTAQKTFKTSSIDHQRLPKQNKSIFDL
SLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQYLEDLGLNYYALPESLGGVASEQNIVSNILIAEDLAQGDF
SLSAGLLSTFSVINALTRWGSESTQSKYLTAFSEDPNLKATFATQENTPAFNPFKLKTQATLQNNHYFLSGEKTLVILGE
SADLILVTAMLDGQPEVFIVERDPTISIKSAPAMGLKAAQTMSLYFDHTPAVLLGDNDFDYSAFIDLGSLMWCAMAVGTC
EAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDAMRMLIWNAASLAEAGQAFHREAYLARLLCAEKSMRIGTDG
VQLLGGHGFTKEHPVERWYRDLRATAILHSGLHA

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=363, Percent_Identity=28.3746556473829, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI226958412, Length=362, Percent_Identity=29.5580110497238, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI187960098, Length=395, Percent_Identity=26.8354430379747, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI4557231, Length=395, Percent_Identity=26.8354430379747, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI4557233, Length=378, Percent_Identity=26.7195767195767, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI226958414, Length=325, Percent_Identity=29.2307692307692, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI4501857, Length=361, Percent_Identity=24.6537396121884, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI4557235, Length=424, Percent_Identity=25, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI76496475, Length=368, Percent_Identity=25.2717391304348, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI21361497, Length=343, Percent_Identity=23.3236151603499, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI7656849, Length=368, Percent_Identity=23.3695652173913, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI87081958, Length=369, Percent_Identity=26.5582655826558, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786223, Length=380, Percent_Identity=24.2105263157895, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17506239, Length=355, Percent_Identity=29.0140845070423, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17508101, Length=360, Percent_Identity=27.7777777777778, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17569725, Length=369, Percent_Identity=27.9132791327913, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=28.0104712041885, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17538396, Length=405, Percent_Identity=27.1604938271605, Blast_Score=121, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17570075, Length=361, Percent_Identity=24.0997229916898, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71990804, Length=283, Percent_Identity=26.8551236749117, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71985184, Length=390, Percent_Identity=23.8461538461538, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=223, Percent_Identity=27.3542600896861, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17505929, Length=399, Percent_Identity=21.8045112781955, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24666513, Length=362, Percent_Identity=29.0055248618785, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI21356377, Length=383, Percent_Identity=27.4151436031332, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24660351, Length=360, Percent_Identity=27.5, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24646207, Length=371, Percent_Identity=27.2237196765499, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21355753, Length=373, Percent_Identity=25.7372654155496, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281363737, Length=391, Percent_Identity=22.7621483375959, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 47990; Mature: 47990

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFAMSDMINKAQGFGLSLITKIAGSDVLDQLKLRKFLEKSLYQGSKSGFKAISTAQKTF
CCCCHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KTSSIDHQRLPKQNKSIFDLSLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQ
HCCCCCHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHH
YLEDLGLNYYALPESLGGVASEQNIVSNILIAEDLAQGDFSLSAGLLSTFSVINALTRWG
HHHHHCCCEEECCHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
SESTQSKYLTAFSEDPNLKATFATQENTPAFNPFKLKTQATLQNNHYFLSGEKTLVILGE
CCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCEEEEEEEEECCCEEEEECCEEEEEEEC
SADLILVTAMLDGQPEVFIVERDPTISIKSAPAMGLKAAQTMSLYFDHTPAVLLGDNDFD
CCCEEEEEEEECCCCCEEEEECCCEEEECCCCCCCHHHHHHEEEEECCCCEEEECCCCCC
YSAFIDLGSLMWCAMAVGTCEAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
MRMLIWNAASLAEAGQAFHREAYLARLLCAEKSMRIGTDGVQLLGGHGFTKEHPVERWYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEECCCCCCCCCCHHHHHH
DLRATAILHSGLHA
HHHHHHHHHCCCCC
>Mature Secondary Structure
MEFAMSDMINKAQGFGLSLITKIAGSDVLDQLKLRKFLEKSLYQGSKSGFKAISTAQKTF
CCCCHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KTSSIDHQRLPKQNKSIFDLSLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQ
HCCCCCHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHH
YLEDLGLNYYALPESLGGVASEQNIVSNILIAEDLAQGDFSLSAGLLSTFSVINALTRWG
HHHHHCCCEEECCHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
SESTQSKYLTAFSEDPNLKATFATQENTPAFNPFKLKTQATLQNNHYFLSGEKTLVILGE
CCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCEEEEEEEEECCCEEEEECCEEEEEEEC
SADLILVTAMLDGQPEVFIVERDPTISIKSAPAMGLKAAQTMSLYFDHTPAVLLGDNDFD
CCCEEEEEEEECCCCCEEEEECCCEEEECCCCCCCHHHHHHEEEEECCCCEEEECCCCCC
YSAFIDLGSLMWCAMAVGTCEAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
MRMLIWNAASLAEAGQAFHREAYLARLLCAEKSMRIGTDGVQLLGGHGFTKEHPVERWYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEECCCCCCCCCCHHHHHH
DLRATAILHSGLHA
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]