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The map label for this gene is ubiB [C]

Identifier: 50084591

GI number: 50084591

Start: 1408763

End: 1410163

Strand: Reverse

Name: ubiB [C]

Synonym: ACIAD1414

Alternate gene names: 50084591

Gene position: 1410163-1408763 (Counterclockwise)

Preceding gene: 50084592

Following gene: 50084590

Centisome position: 39.19

GC content: 42.97

Gene sequence:

>1401_bases
GTGTTTCACTGCAAAGGATTATATATGTCAGATCAGAACGATAAGCTTAAGAATTTAAAAACTTCTTCGATGGACCGACG
CTTATCGATCGCCAAGGCCTCATTACTTGCTGGTACTCGCTGGGCGACTGCCAGTGCAACCTCGATGTTTTCCAGTGAAG
CAGAAAAAGAGAAAAAGCGTAAGAAAGCCATGACTGAACAGGCTAACTACCTCGTTTCCGAGATTGGGAAGCTGAAAGGT
TCAATTGTTAAGATTGGCCAAATGATGGCGCTTTATGGCGAGCATTTCTTACCAGAAGAGATCACGCAGGCTCTCAATAC
ACTTAACAATCAAACCGTGGCTTTGGCATGGCCAGCAATCAAGGCTCACTTACAAGAGCAGCTTGGCAGCAAGCTGGATG
ATCTGATTATTGATCATGAACCTATTGGTACCGCATCATTGGCACAAGTCCACCGTGCGACACGTAAATCTGATGGTTTG
GAACTGGTTCTAAAAATTCAATATCCAGGCGTCGCAGAAGCAATCGACTCGGATATGAGCCTATTTAAAAATATGCTCAA
ATTAACACGTATGGTACCCCAAACCCGTGAATTTGATCAGTGGTTTGATGAAGTACGTGAAATGATGCACCGTGAGGTCA
GTTATGATATTGAAGCAGCAACAACACGGCGCTTTGCTGAACGTCTGAAAACAGATCCGCGTTATGCCGTGCCACAAATT
ATAGATGCATATTGCACGACTAAAATTCTGTGCATGACTTTTGAACGTGGCGTGCCGATTAATAGCCCTGTCATGCTGTC
TTTGCCGCAAGAAAGACGCAATAAACTCGGTGAAGCATCACTTGAAATTGCTGTACGTGAAATTTTCGAATGGGGCGAGA
TGCAAACTGACCCAAATTTCGGGAATTACCTAGTCCGCCTTGGCAATGGTACTGATATTCAAGATAAAATTGTGTTACTG
GACTTTGGCGCAATTCGCCAGTTTGATGAACATCTGCTTAGCGTTGCACGTAACCTGATCCGTGCAGGCTATAACCATAG
TAATGAAGAAATGGTTCGTGCCATGACTGGTTATAGCTTCTTTGATTCGATTCCAGAAAGCATTAAACCAGACATGGCGA
AAGTCTTTTTACTGGCGACTGAAGCATTTAGCTGCCCAGAAAATAATCCTGATATGCCAACAGGCTTGATGGATGAAGAT
AATCGTTATGATTGGAAAAAGAGTCAGTTACATAGTCGTGTCATGCAACAGGCCAGCAAATCGATGGCCTCTCGTTATTT
CTCGGTTCCACCTAAAGAATTTATGTTTATTAGTCGTAAGTTCATTGGTGCTTATACCTTTATGACTGTCATTGAAGCCA
AAACCAATGTTCGCCGCATGATTAGCCATTTTGTAAAATAA

Upstream 100 bases:

>100_bases
TGATGCTACCTTTACATTTCATCTTTTAAACAGCATATGACTGTTTTAATACGATCAGACCATGTAATATTCGTTACAAT
TATTCTCTCCACTCTTCTGC

Downstream 100 bases:

>100_bases
ATTGTTTGACCAGAATGCCATCTGTCATTCTGGTCAATTCATCCAAATCTTATTTTTTCCTTGTTTGTATTTTCATATAA
AAAACATAACTCTAAAATCA

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MFHCKGLYMSDQNDKLKNLKTSSMDRRLSIAKASLLAGTRWATASATSMFSSEAEKEKKRKKAMTEQANYLVSEIGKLKG
SIVKIGQMMALYGEHFLPEEITQALNTLNNQTVALAWPAIKAHLQEQLGSKLDDLIIDHEPIGTASLAQVHRATRKSDGL
ELVLKIQYPGVAEAIDSDMSLFKNMLKLTRMVPQTREFDQWFDEVREMMHREVSYDIEAATTRRFAERLKTDPRYAVPQI
IDAYCTTKILCMTFERGVPINSPVMLSLPQERRNKLGEASLEIAVREIFEWGEMQTDPNFGNYLVRLGNGTDIQDKIVLL
DFGAIRQFDEHLLSVARNLIRAGYNHSNEEMVRAMTGYSFFDSIPESIKPDMAKVFLLATEAFSCPENNPDMPTGLMDED
NRYDWKKSQLHSRVMQQASKSMASRYFSVPPKEFMFISRKFIGAYTFMTVIEAKTNVRRMISHFVK

Sequences:

>Translated_466_residues
MFHCKGLYMSDQNDKLKNLKTSSMDRRLSIAKASLLAGTRWATASATSMFSSEAEKEKKRKKAMTEQANYLVSEIGKLKG
SIVKIGQMMALYGEHFLPEEITQALNTLNNQTVALAWPAIKAHLQEQLGSKLDDLIIDHEPIGTASLAQVHRATRKSDGL
ELVLKIQYPGVAEAIDSDMSLFKNMLKLTRMVPQTREFDQWFDEVREMMHREVSYDIEAATTRRFAERLKTDPRYAVPQI
IDAYCTTKILCMTFERGVPINSPVMLSLPQERRNKLGEASLEIAVREIFEWGEMQTDPNFGNYLVRLGNGTDIQDKIVLL
DFGAIRQFDEHLLSVARNLIRAGYNHSNEEMVRAMTGYSFFDSIPESIKPDMAKVFLLATEAFSCPENNPDMPTGLMDED
NRYDWKKSQLHSRVMQQASKSMASRYFSVPPKEFMFISRKFIGAYTFMTVIEAKTNVRRMISHFVK
>Mature_466_residues
MFHCKGLYMSDQNDKLKNLKTSSMDRRLSIAKASLLAGTRWATASATSMFSSEAEKEKKRKKAMTEQANYLVSEIGKLKG
SIVKIGQMMALYGEHFLPEEITQALNTLNNQTVALAWPAIKAHLQEQLGSKLDDLIIDHEPIGTASLAQVHRATRKSDGL
ELVLKIQYPGVAEAIDSDMSLFKNMLKLTRMVPQTREFDQWFDEVREMMHREVSYDIEAATTRRFAERLKTDPRYAVPQI
IDAYCTTKILCMTFERGVPINSPVMLSLPQERRNKLGEASLEIAVREIFEWGEMQTDPNFGNYLVRLGNGTDIQDKIVLL
DFGAIRQFDEHLLSVARNLIRAGYNHSNEEMVRAMTGYSFFDSIPESIKPDMAKVFLLATEAFSCPENNPDMPTGLMDED
NRYDWKKSQLHSRVMQQASKSMASRYFSVPPKEFMFISRKFIGAYTFMTVIEAKTNVRRMISHFVK

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI34147522, Length=425, Percent_Identity=27.7647058823529, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI27363457, Length=439, Percent_Identity=24.8291571753986, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI217416386, Length=341, Percent_Identity=26.6862170087977, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI40254938, Length=273, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI41393593, Length=265, Percent_Identity=27.1698113207547, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI217035081, Length=206, Percent_Identity=30.0970873786408, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI2367309, Length=256, Percent_Identity=22.65625, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32565180, Length=424, Percent_Identity=24.5283018867925, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17559152, Length=296, Percent_Identity=28.3783783783784, Blast_Score=98, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6321319, Length=397, Percent_Identity=27.455919395466, Blast_Score=143, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6323282, Length=261, Percent_Identity=25.2873563218391, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI18859849, Length=409, Percent_Identity=27.6283618581907, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI22024280, Length=289, Percent_Identity=26.2975778546713, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24662575, Length=306, Percent_Identity=22.2222222222222, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 53198; Mature: 53198

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHCKGLYMSDQNDKLKNLKTSSMDRRLSIAKASLLAGTRWATASATSMFSSEAEKEKKR
CCEECCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KKAMTEQANYLVSEIGKLKGSIVKIGQMMALYGEHFLPEEITQALNTLNNQTVALAWPAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEHHHH
KAHLQEQLGSKLDDLIIDHEPIGTASLAQVHRATRKSDGLELVLKIQYPGVAEAIDSDMS
HHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHH
LFKNMLKLTRMVPQTREFDQWFDEVREMMHREVSYDIEAATTRRFAERLKTDPRYAVPQI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHH
IDAYCTTKILCMTFERGVPINSPVMLSLPQERRNKLGEASLEIAVREIFEWGEMQTDPNF
HHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
GNYLVRLGNGTDIQDKIVLLDFGAIRQFDEHLLSVARNLIRAGYNHSNEEMVRAMTGYSF
CCEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FDSIPESIKPDMAKVFLLATEAFSCPENNPDMPTGLMDEDNRYDWKKSQLHSRVMQQASK
HHHCCHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
SMASRYFSVPPKEFMFISRKFIGAYTFMTVIEAKTNVRRMISHFVK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFHCKGLYMSDQNDKLKNLKTSSMDRRLSIAKASLLAGTRWATASATSMFSSEAEKEKKR
CCEECCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KKAMTEQANYLVSEIGKLKGSIVKIGQMMALYGEHFLPEEITQALNTLNNQTVALAWPAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEHHHH
KAHLQEQLGSKLDDLIIDHEPIGTASLAQVHRATRKSDGLELVLKIQYPGVAEAIDSDMS
HHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHH
LFKNMLKLTRMVPQTREFDQWFDEVREMMHREVSYDIEAATTRRFAERLKTDPRYAVPQI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHH
IDAYCTTKILCMTFERGVPINSPVMLSLPQERRNKLGEASLEIAVREIFEWGEMQTDPNF
HHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
GNYLVRLGNGTDIQDKIVLLDFGAIRQFDEHLLSVARNLIRAGYNHSNEEMVRAMTGYSF
CCEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FDSIPESIKPDMAKVFLLATEAFSCPENNPDMPTGLMDEDNRYDWKKSQLHSRVMQQASK
HHHCCHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
SMASRYFSVPPKEFMFISRKFIGAYTFMTVIEAKTNVRRMISHFVK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA