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The map label for this gene is yngJ [H]

Identifier: 50084589

GI number: 50084589

Start: 1406016

End: 1407221

Strand: Reverse

Name: yngJ [H]

Synonym: ACIAD1412

Alternate gene names: 50084589

Gene position: 1407221-1406016 (Counterclockwise)

Preceding gene: 50084590

Following gene: 50084587

Centisome position: 39.1

GC content: 44.2

Gene sequence:

>1206_bases
ATGAATTTACAAGACCCTAAAAAATTTAAAATGATGGTCAACCAAGCCCATGATGTCGCACTCAATGTTTTACGTCCCAT
CTCACGTAAATATGACAAAGCAGAACATGCCTATCCTAAAGAATTAGACATGCTCGCTTCACTCATTGACGGAATGAATG
AAGGTGGCGATGGTATAAATGCAGGAGCCACGGGTGCAGGTAAACGAGGCGAGAATGAACAACAAGGCATCCGTAATGGA
ACCAATATGTCTACAGCGCTCGGCATTATCGAAATGTGTTATGGAGATACAGGCCTATTACTGAGTATGCCTCGCCAAGG
ACTAGGAAACTCTGCAATAGCAGCCGTAGCGAATGATGAACAGTTAGAACGATTTAAAGGCACATGGGCAGCCATGGCAA
TTACCGAGCCTGGATGTGGTTCAGACTCAGCCGCGATCCGAACCACGGCCGTCAAAGCTGGTGATGAATATATTTTAAAT
GGTGAGAAGATCTATGTAACCTCAGGAGAAAGAGCTGACTCAGTCGTGGTTTGGGCAACACTTGATCGGAAACTAGGCCG
CGCTGCCATCAAGTCCTTTGTAGTCCCAAAAGGTACGCCTGGCATGAAAGTCGAGCGCCTTGAGCATAAACTTGGAATTA
AGGCCTCCGATACCGCAGCCATTAGTTTTATCGACTGTCGAGTTCCTGCTGCCAACTTATTAGGCAATGCCGAGATCGAT
GTTGCCAAAGGTTTTGCAGGTGTGATGGAAACTTTTGACAATACGCGCCCATTAGTTGCCGCAATGGCGGTGGGTTGTGC
TAAAGCATCTTTAGAGCGCATTAAAGAAATATTTAAAGATGAACTCGACACAGACTATGCAACACCGTATTTACAAACTT
CTTTTATCGCGGCTCAAATCTATCGGATGGAAGCAGAATGGGAAGCAGCACGGCTACTGACACTTAAAGCAACCTGGATG
GCAGATAATAAAAAACCAAATTCCAAAGAAGCATCGATTGCCAAAGCCAAAGCAGGCCGTATCTGTAATGAAATTACGCT
CAAATGTGTCGAACTTGCTGCCAGTGTTGGATACAACGAAGATGAATTACTAGAAAAATGGGCACGTGATTCAAAAATTC
TGGATATTTTTGAAGGTACACAGCAAATTCAACTTTTGATTATTGCACGTCGTGAACTCGGAAAGTCATCTAGCGAACTG
AAATAA

Upstream 100 bases:

>100_bases
CATCCTGTCGAGCGTTGGTATCGGGATTTACGTGCAACTGCTATTTTGCATTCAGGTTTACATGCTTAAGTATTGATTAA
AATAACTCCAAGGATTAGCC

Downstream 100 bases:

>100_bases
TGGCTTAATCTAATAAAAAGAGAGTCACTTAGACTCTCTTTTAAAATAAGGTCTGATTACTTGCCGTTTTCTATATTCGG
GTCAGTCAAACCAAACTTGG

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MNLQDPKKFKMMVNQAHDVALNVLRPISRKYDKAEHAYPKELDMLASLIDGMNEGGDGINAGATGAGKRGENEQQGIRNG
TNMSTALGIIEMCYGDTGLLLSMPRQGLGNSAIAAVANDEQLERFKGTWAAMAITEPGCGSDSAAIRTTAVKAGDEYILN
GEKIYVTSGERADSVVVWATLDRKLGRAAIKSFVVPKGTPGMKVERLEHKLGIKASDTAAISFIDCRVPAANLLGNAEID
VAKGFAGVMETFDNTRPLVAAMAVGCAKASLERIKEIFKDELDTDYATPYLQTSFIAAQIYRMEAEWEAARLLTLKATWM
ADNKKPNSKEASIAKAKAGRICNEITLKCVELAASVGYNEDELLEKWARDSKILDIFEGTQQIQLLIIARRELGKSSSEL
K

Sequences:

>Translated_401_residues
MNLQDPKKFKMMVNQAHDVALNVLRPISRKYDKAEHAYPKELDMLASLIDGMNEGGDGINAGATGAGKRGENEQQGIRNG
TNMSTALGIIEMCYGDTGLLLSMPRQGLGNSAIAAVANDEQLERFKGTWAAMAITEPGCGSDSAAIRTTAVKAGDEYILN
GEKIYVTSGERADSVVVWATLDRKLGRAAIKSFVVPKGTPGMKVERLEHKLGIKASDTAAISFIDCRVPAANLLGNAEID
VAKGFAGVMETFDNTRPLVAAMAVGCAKASLERIKEIFKDELDTDYATPYLQTSFIAAQIYRMEAEWEAARLLTLKATWM
ADNKKPNSKEASIAKAKAGRICNEITLKCVELAASVGYNEDELLEKWARDSKILDIFEGTQQIQLLIIARRELGKSSSEL
K
>Mature_401_residues
MNLQDPKKFKMMVNQAHDVALNVLRPISRKYDKAEHAYPKELDMLASLIDGMNEGGDGINAGATGAGKRGENEQQGIRNG
TNMSTALGIIEMCYGDTGLLLSMPRQGLGNSAIAAVANDEQLERFKGTWAAMAITEPGCGSDSAAIRTTAVKAGDEYILN
GEKIYVTSGERADSVVVWATLDRKLGRAAIKSFVVPKGTPGMKVERLEHKLGIKASDTAAISFIDCRVPAANLLGNAEID
VAKGFAGVMETFDNTRPLVAAMAVGCAKASLERIKEIFKDELDTDYATPYLQTSFIAAQIYRMEAEWEAARLLTLKATWM
ADNKKPNSKEASIAKAKAGRICNEITLKCVELAASVGYNEDELLEKWARDSKILDIFEGTQQIQLLIIARRELGKSSSEL
K

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557231, Length=315, Percent_Identity=37.4603174603175, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI187960098, Length=315, Percent_Identity=37.4603174603175, Blast_Score=185, Evalue=8e-47,
Organism=Homo sapiens, GI4557233, Length=396, Percent_Identity=31.5656565656566, Blast_Score=175, Evalue=8e-44,
Organism=Homo sapiens, GI4501859, Length=272, Percent_Identity=35.2941176470588, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI4501857, Length=294, Percent_Identity=29.9319727891156, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI7656849, Length=290, Percent_Identity=29.6551724137931, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI226958414, Length=274, Percent_Identity=27.7372262773723, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI226958412, Length=273, Percent_Identity=27.8388278388278, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI76496475, Length=270, Percent_Identity=30.7407407407407, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI4557235, Length=299, Percent_Identity=29.4314381270903, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI21361497, Length=334, Percent_Identity=27.5449101796407, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI4503943, Length=318, Percent_Identity=23.8993710691824, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI7669494, Length=263, Percent_Identity=25.0950570342205, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1786223, Length=277, Percent_Identity=26.7148014440433, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI87081958, Length=264, Percent_Identity=24.6212121212121, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17570075, Length=316, Percent_Identity=38.2911392405063, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17569725, Length=339, Percent_Identity=35.693215339233, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17534899, Length=394, Percent_Identity=32.741116751269, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17508101, Length=397, Percent_Identity=29.9748110831234, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17506239, Length=274, Percent_Identity=31.3868613138686, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71990804, Length=222, Percent_Identity=31.0810810810811, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17533517, Length=274, Percent_Identity=27.007299270073, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17505929, Length=305, Percent_Identity=27.5409836065574, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17551932, Length=303, Percent_Identity=27.3927392739274, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17538396, Length=270, Percent_Identity=26.2962962962963, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17531909, Length=245, Percent_Identity=28.1632653061224, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71985184, Length=314, Percent_Identity=26.7515923566879, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17534353, Length=263, Percent_Identity=25.8555133079848, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI32563615, Length=165, Percent_Identity=30.3030303030303, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=181, Percent_Identity=30.3867403314917, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71982178, Length=213, Percent_Identity=27.6995305164319, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17531913, Length=180, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562446, Length=281, Percent_Identity=27.0462633451957, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24660351, Length=318, Percent_Identity=37.1069182389937, Blast_Score=178, Evalue=6e-45,
Organism=Drosophila melanogaster, GI21356377, Length=398, Percent_Identity=32.6633165829146, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24646207, Length=319, Percent_Identity=31.974921630094, Blast_Score=164, Evalue=8e-41,
Organism=Drosophila melanogaster, GI24666513, Length=288, Percent_Identity=32.6388888888889, Blast_Score=148, Evalue=8e-36,
Organism=Drosophila melanogaster, GI281363737, Length=325, Percent_Identity=29.8461538461538, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21355753, Length=277, Percent_Identity=27.0758122743682, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI19920834, Length=293, Percent_Identity=25.938566552901, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43502; Mature: 43502

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLQDPKKFKMMVNQAHDVALNVLRPISRKYDKAEHAYPKELDMLASLIDGMNEGGDGIN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
AGATGAGKRGENEQQGIRNGTNMSTALGIIEMCYGDTGLLLSMPRQGLGNSAIAAVANDE
CCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCHH
QLERFKGTWAAMAITEPGCGSDSAAIRTTAVKAGDEYILNGEKIYVTSGERADSVVVWAT
HHHHHCCCEEEEEEECCCCCCCCCCEEEEEEECCCCEEECCCEEEEECCCCCCCEEEEEE
LDRKLGRAAIKSFVVPKGTPGMKVERLEHKLGIKASDTAAISFIDCRVPAANLLGNAEID
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHCCCCCEE
VAKGFAGVMETFDNTRPLVAAMAVGCAKASLERIKEIFKDELDTDYATPYLQTSFIAAQI
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
YRMEAEWEAARLLTLKATWMADNKKPNSKEASIAKAKAGRICNEITLKCVELAASVGYNE
HHHHCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
DELLEKWARDSKILDIFEGTQQIQLLIIARRELGKSSSELK
HHHHHHHHCCCCEEHHHCCCCCEEEEEEEHHHHCCCCCCCC
>Mature Secondary Structure
MNLQDPKKFKMMVNQAHDVALNVLRPISRKYDKAEHAYPKELDMLASLIDGMNEGGDGIN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
AGATGAGKRGENEQQGIRNGTNMSTALGIIEMCYGDTGLLLSMPRQGLGNSAIAAVANDE
CCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCHH
QLERFKGTWAAMAITEPGCGSDSAAIRTTAVKAGDEYILNGEKIYVTSGERADSVVVWAT
HHHHHCCCEEEEEEECCCCCCCCCCEEEEEEECCCCEEECCCEEEEECCCCCCCEEEEEE
LDRKLGRAAIKSFVVPKGTPGMKVERLEHKLGIKASDTAAISFIDCRVPAANLLGNAEID
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHCCCCCEE
VAKGFAGVMETFDNTRPLVAAMAVGCAKASLERIKEIFKDELDTDYATPYLQTSFIAAQI
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
YRMEAEWEAARLLTLKATWMADNKKPNSKEASIAKAKAGRICNEITLKCVELAASVGYNE
HHHHCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
DELLEKWARDSKILDIFEGTQQIQLLIIARRELGKSSSELK
HHHHHHHHCCCCEEHHHCCCCCEEEEEEEHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]