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The map label for this gene is aarA [H]

Identifier: 50084260

GI number: 50084260

Start: 1055779

End: 1056609

Strand: Reverse

Name: aarA [H]

Synonym: ACIAD1060

Alternate gene names: 50084260

Gene position: 1056609-1055779 (Counterclockwise)

Preceding gene: 50084263

Following gene: 50084257

Centisome position: 29.36

GC content: 42.36

Gene sequence:

>831_bases
ATGTCTGAACTTACACCTCCGCAGATAAATCGTAAACTTGATCTTCACGCATGGTGGATGACCGCCATGCTGATTGCTAT
TAATGTAGGTTTATTTGTCTGGCAAATTTTGCATGGGGTAGATGCCAGTAATCCGGCACCTGCGGATGCAATTCGCTGGG
GAGCTGATTTTGCACCCCTTACCTATCTGGAACAGCCGCAACGCCTCATCACCAGCATGTTTTTCCATTTTGGGTTTGTA
CATTTGGCACTCAACATGTGGGCTTTATATATTTTTGGAAGTCTTGCTGAGCAAATATTGGGACGTTTTTACTTCATAGG
CTTATATTTTTTAGCAGGTTTAATGGGAAGCTTACTCAGTGGTTATATGAGTATTCAGGACAGCTATGAACTGCTGAACC
ATTTCAATTCCATTGCGGGAAGTCAGTCGTCGCTCATCCCACATATTGCAGCAGGAGCTTCAGGGGCAGTGATGGGGCTT
GGCGGCGCACTTACCATTCTTGCTTTTTTTCCGCCATTACCTTTACAGCGCTTTATTTTAGATAAGAAAGCATTGTTGAT
TGTGATGGGGATCAATCTGGCATTCGGATTTATGACCATTGGCATTAATAATTCTGCACATATCGGTGGCATGATCATGG
GCGCATTTCTGGTATTTATCTGGTATTTATTTCAAAAAATGAAGGCGCAAATGCTAGGAAACTTAATAGGGCTAGTGAGC
GGTAGTCTTGTTTGTGTTGTTTTTTATCAATATTGCATTAGCTTACTTCCACCGATTACCCCATTTTGGCAAATGATTTT
GTCACAAATGAGTCAGCAGCTTGGACGCTAA

Upstream 100 bases:

>100_bases
GCGAACAATAAATCTTTTCATGCCAGTTTGTTTCTCCAGAAATATTGATAATTCATGCTAAGCTAATCGAAATCTTATCC
ATGTATAACAAAAGCATAGC

Downstream 100 bases:

>100_bases
CGCCATCCAAGCTGATACTTATTATGATGACTGGTTAAGTTCCCTTAAACTTTGCAAAGGTGGAATGTCACACAAATAAC
TTAATCGGTAGCGACCAATC

Product: hypothetical protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MSELTPPQINRKLDLHAWWMTAMLIAINVGLFVWQILHGVDASNPAPADAIRWGADFAPLTYLEQPQRLITSMFFHFGFV
HLALNMWALYIFGSLAEQILGRFYFIGLYFLAGLMGSLLSGYMSIQDSYELLNHFNSIAGSQSSLIPHIAAGASGAVMGL
GGALTILAFFPPLPLQRFILDKKALLIVMGINLAFGFMTIGINNSAHIGGMIMGAFLVFIWYLFQKMKAQMLGNLIGLVS
GSLVCVVFYQYCISLLPPITPFWQMILSQMSQQLGR

Sequences:

>Translated_276_residues
MSELTPPQINRKLDLHAWWMTAMLIAINVGLFVWQILHGVDASNPAPADAIRWGADFAPLTYLEQPQRLITSMFFHFGFV
HLALNMWALYIFGSLAEQILGRFYFIGLYFLAGLMGSLLSGYMSIQDSYELLNHFNSIAGSQSSLIPHIAAGASGAVMGL
GGALTILAFFPPLPLQRFILDKKALLIVMGINLAFGFMTIGINNSAHIGGMIMGAFLVFIWYLFQKMKAQMLGNLIGLVS
GSLVCVVFYQYCISLLPPITPFWQMILSQMSQQLGR
>Mature_275_residues
SELTPPQINRKLDLHAWWMTAMLIAINVGLFVWQILHGVDASNPAPADAIRWGADFAPLTYLEQPQRLITSMFFHFGFVH
LALNMWALYIFGSLAEQILGRFYFIGLYFLAGLMGSLLSGYMSIQDSYELLNHFNSIAGSQSSLIPHIAAGASGAVMGLG
GALTILAFFPPLPLQRFILDKKALLIVMGINLAFGFMTIGINNSAHIGGMIMGAFLVFIWYLFQKMKAQMLGNLIGLVSG
SLVCVVFYQYCISLLPPITPFWQMILSQMSQQLGR

Specific function: Rhomboid serine protease that catalyzes intramembrane proteolysis. Mediates quorum-sensing and the subsequent regulation of target genes via activation of the Tat protein export system. Catalyzes the proteolytic activation of tatA by removal of its N- ter

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 30552; Mature: 30421

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SELTPPQINRKLDLHAWWMTAMLIAINVGLFVWQILHGVDASNPAPADAIRWGADFAPL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCHH
TYLEQPQRLITSMFFHFGFVHLALNMWALYIFGSLAEQILGRFYFIGLYFLAGLMGSLLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYMSIQDSYELLNHFNSIAGSQSSLIPHIAAGASGAVMGLGGALTILAFFPPLPLQRFIL
HHHHHHHHHHHHHHHHHHCCCCHHCCHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
DKKALLIVMGINLAFGFMTIGINNSAHIGGMIMGAFLVFIWYLFQKMKAQMLGNLIGLVS
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSLVCVVFYQYCISLLPPITPFWQMILSQMSQQLGR
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8051030 [H]