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The map label for this gene is estR

Identifier: 50084263

GI number: 50084263

Start: 1059641

End: 1060546

Strand: Reverse

Name: estR

Synonym: ACIAD1063

Alternate gene names: 50084263

Gene position: 1060546-1059641 (Counterclockwise)

Preceding gene: 50084264

Following gene: 50084260

Centisome position: 29.47

GC content: 43.6

Gene sequence:

>906_bases
ATGGCTGCATTACCCTCCTTAAGACAGCTGTCATATTTAGTTACGCTGTCGGAAACATTGCACTTTACAGAAGCAGCACG
CCGTTCATTTGTCACTCAATCGACATTGTCTGGCGGTATCATGGAATTGGAACGTTTGCTTGGCGGCGTACTGGTCGAAC
GCGATCGTCAAAATGTACGCTTAACGCCTCTTGGGGAACAAGTGGTAGCTCGCGCCCGTGTCCTACTGGCAGATGCGCAA
GATTTAATGCGGCTCAGTCGGGAAATGAGTGAACCACTGACAGGTGATCTTCATTTAGGCATTATTCCAACGATTGCACC
TTTCATCCTGACCCAGTTGCTTGATGAAGTACACAAACAACTTCCCAAGATCCAGCTACATTTGCACGAAGCACAAAGCG
AAAAAATCGTTGAGCGCCTAGAGCATGGTAATTTGGATATGGTCGTATTGGCTTTGCCTTTCGATACACGTGGTTTGAAA
GTTGCCGACATTGCCAAAGAGAATTTGTATCTGGTCTGCAATAAGCATGACAAACATTCGGTAAATGCACACTCTTTAGA
TGATCTGGATTTGTCTCGTCTGATGTTGCTCGAAGAAGGCCACTGCTTACGAGATCATGCTTTAAGTGCTTGTCCTATCG
GTGAACGCAAAAATGACAATCGTTTAAAAGCCAGCTCTTTGCCCACACTGGTCGAAATGGTATCATCAAATCTCGGTTTT
ACGCTATTGCCAGAAATTGCAATCAATACACATATGCTCAAATTCAATGATGATTTACTGGTTAAAGAAATTGAGAATGC
ACCAAGCCGTACACTTGCCCTGATTACCAGAAAGAGTACCCCGCTGCAAAGTGAATTTGATGTGATTTTAGATATCTTAA
AACGAATTACAGCAACTTTGCATTAA

Upstream 100 bases:

>100_bases
GAATTAATTCAGGGAATGGGACATGATATTCCACCACATTTTATTCCCCAACTTAGTTATCTCTTTGCTCATCACTTTAG
ATCATAAGCACTAGGACATT

Downstream 100 bases:

>100_bases
GTCTACATTGATTAAATTTTATGTTCAGAATGAAAAAAGGAGTCTTTAAAGACTCCTTTTTTTGTCATATTATTTTGGTA
TTAGGCAAAGATAGACAGCA

Product: esterase operon transcriptional regulator

Products: NA

Alternate protein names: Esterase operon transcriptional regulator

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MAALPSLRQLSYLVTLSETLHFTEAARRSFVTQSTLSGGIMELERLLGGVLVERDRQNVRLTPLGEQVVARARVLLADAQ
DLMRLSREMSEPLTGDLHLGIIPTIAPFILTQLLDEVHKQLPKIQLHLHEAQSEKIVERLEHGNLDMVVLALPFDTRGLK
VADIAKENLYLVCNKHDKHSVNAHSLDDLDLSRLMLLEEGHCLRDHALSACPIGERKNDNRLKASSLPTLVEMVSSNLGF
TLLPEIAINTHMLKFNDDLLVKEIENAPSRTLALITRKSTPLQSEFDVILDILKRITATLH

Sequences:

>Translated_301_residues
MAALPSLRQLSYLVTLSETLHFTEAARRSFVTQSTLSGGIMELERLLGGVLVERDRQNVRLTPLGEQVVARARVLLADAQ
DLMRLSREMSEPLTGDLHLGIIPTIAPFILTQLLDEVHKQLPKIQLHLHEAQSEKIVERLEHGNLDMVVLALPFDTRGLK
VADIAKENLYLVCNKHDKHSVNAHSLDDLDLSRLMLLEEGHCLRDHALSACPIGERKNDNRLKASSLPTLVEMVSSNLGF
TLLPEIAINTHMLKFNDDLLVKEIENAPSRTLALITRKSTPLQSEFDVILDILKRITATLH
>Mature_300_residues
AALPSLRQLSYLVTLSETLHFTEAARRSFVTQSTLSGGIMELERLLGGVLVERDRQNVRLTPLGEQVVARARVLLADAQD
LMRLSREMSEPLTGDLHLGIIPTIAPFILTQLLDEVHKQLPKIQLHLHEAQSEKIVERLEHGNLDMVVLALPFDTRGLKV
ADIAKENLYLVCNKHDKHSVNAHSLDDLDLSRLMLLEEGHCLRDHALSACPIGERKNDNRLKASSLPTLVEMVSSNLGFT
LLPEIAINTHMLKFNDDLLVKEIENAPSRTLALITRKSTPLQSEFDVILDILKRITATLH

Specific function: Transcriptional regulator of the esterase operon

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790399, Length=290, Percent_Identity=34.1379310344828, Blast_Score=177, Evalue=9e-46,
Organism=Escherichia coli, GI1788748, Length=294, Percent_Identity=27.2108843537415, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI157672245, Length=277, Percent_Identity=27.4368231046931, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788297, Length=251, Percent_Identity=27.8884462151394, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787879, Length=152, Percent_Identity=32.8947368421053, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790208, Length=252, Percent_Identity=27.7777777777778, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788887, Length=281, Percent_Identity=24.9110320284698, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ESTR_ACIAD (P52667)

Other databases:

- EMBL:   X88895
- EMBL:   Z46863
- EMBL:   CR543861
- PIR:   S57531
- RefSeq:   YP_045773.1
- ProteinModelPortal:   P52667
- STRING:   P52667
- GeneID:   2880688
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1063
- NMPDR:   fig|62977.3.peg.1213
- eggNOG:   COG0583
- HOGENOM:   HBG685425
- OMA:   QMALANM
- PhylomeDB:   P52667
- ProtClustDB:   CLSK707185
- BioCyc:   ASP62977:ACIAD1063-MONOMER
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate

EC number: NA

Molecular weight: Translated: 33691; Mature: 33560

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALPSLRQLSYLVTLSETLHFTEAARRSFVTQSTLSGGIMELERLLGGVLVERDRQNVR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEE
LTPLGEQVVARARVLLADAQDLMRLSREMSEPLTGDLHLGIIPTIAPFILTQLLDEVHKQ
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHH
LPKIQLHLHEAQSEKIVERLEHGNLDMVVLALPFDTRGLKVADIAKENLYLVCNKHDKHS
CCCEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEHEECCCCEEEEECCCCCCC
VNAHSLDDLDLSRLMLLEEGHCLRDHALSACPIGERKNDNRLKASSLPTLVEMVSSNLGF
CCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCHHCCHHHHHHHHCCCCE
TLLPEIAINTHMLKFNDDLLVKEIENAPSRTLALITRKSTPLQSEFDVILDILKRITATL
EEECHHHHCEEEEEECCCHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHC
H
C
>Mature Secondary Structure 
AALPSLRQLSYLVTLSETLHFTEAARRSFVTQSTLSGGIMELERLLGGVLVERDRQNVR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEE
LTPLGEQVVARARVLLADAQDLMRLSREMSEPLTGDLHLGIIPTIAPFILTQLLDEVHKQ
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHH
LPKIQLHLHEAQSEKIVERLEHGNLDMVVLALPFDTRGLKVADIAKENLYLVCNKHDKHS
CCCEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEHEECCCCEEEEECCCCCCC
VNAHSLDDLDLSRLMLLEEGHCLRDHALSACPIGERKNDNRLKASSLPTLVEMVSSNLGF
CCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCHHCCHHHHHHHHCCCCE
TLLPEIAINTHMLKFNDDLLVKEIENAPSRTLALITRKSTPLQSEFDVILDILKRITATL
EEECHHHHCEEEEEECCCHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHC
H
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA