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The map label for this gene is tesA [C]

Identifier: 50084257

GI number: 50084257

Start: 1051907

End: 1052542

Strand: Reverse

Name: tesA [C]

Synonym: ACIAD1057

Alternate gene names: 50084257

Gene position: 1052542-1051907 (Counterclockwise)

Preceding gene: 50084260

Following gene: 50084255

Centisome position: 29.25

GC content: 39.78

Gene sequence:

>636_bases
ATGCAACTGTATAACATGTTTTTAGACGGGAAATGGGCAAAATGGTTCTTGATTGGTTCATTTAGCGTAATACCTTTTAC
AGTTTCGGCAAAAACCATTCTTATCTTAGGCGACAGTCTGAGTGCGGGTTATGGCATTAACCCCGAACAGGGCTGGGTCG
CTTTATTACAAAAACGTCTGGATCAACAATTTCCCAAGCAGCATAAAGTCATTAATGCCAGTGTAAGTGGGGAAACCACC
AGTGGTGCTTTAGCTCGTTTACCCAAACTACTTACTACTTATCGACCTAATGTGGTGGTCATTGAGCTTGGTGGTAATGA
TGCATTAAGAGGACAACCGCCTCAAATGATTCAAAGTAATCTGGAAAAATTAATCCAGCACAGCCAAAAGGCAAAATCTA
AAGTCGTGGTGTTTGGAATGAAAATACCACCAAATTATGGCACTGCCTATAGTCAGGCATTTGAAAATAATTATAAGGTA
GTGAGTCAAACATATCAGGTTAAGTTGTTGCCATTTTTTCTTGATGGTGTGGCTGGACACAAAAGTCTAATGCAAAATGA
CCAGATCCATCCAAATGCCAAAGCCCAGTCAATCTTGCTAAATAACGCATACCCATATATTAAAGGCGCTTTATAA

Upstream 100 bases:

>100_bases
TGTTATTAAATTGCACCGATTGTGTGACTTGATGGGCAGCGATCATTGGTTGTGGCATGATGGTAAATATCCCCTTTGGT
GAAAACTTCGACAATCTACT

Downstream 100 bases:

>100_bases
AGCGCCTTTAGTCCAATTGCATGACAGCATATCAGGACTTAGAAATCAAAAAAATTGACTTCTCCTGTTTCGAGTGAGTA
CTCAGCACCCACCACAATCA

Product: multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase

Products: NA

Alternate protein names: Aryl-ester hydrolase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MQLYNMFLDGKWAKWFLIGSFSVIPFTVSAKTILILGDSLSAGYGINPEQGWVALLQKRLDQQFPKQHKVINASVSGETT
SGALARLPKLLTTYRPNVVVIELGGNDALRGQPPQMIQSNLEKLIQHSQKAKSKVVVFGMKIPPNYGTAYSQAFENNYKV
VSQTYQVKLLPFFLDGVAGHKSLMQNDQIHPNAKAQSILLNNAYPYIKGAL

Sequences:

>Translated_211_residues
MQLYNMFLDGKWAKWFLIGSFSVIPFTVSAKTILILGDSLSAGYGINPEQGWVALLQKRLDQQFPKQHKVINASVSGETT
SGALARLPKLLTTYRPNVVVIELGGNDALRGQPPQMIQSNLEKLIQHSQKAKSKVVVFGMKIPPNYGTAYSQAFENNYKV
VSQTYQVKLLPFFLDGVAGHKSLMQNDQIHPNAKAQSILLNNAYPYIKGAL
>Mature_211_residues
MQLYNMFLDGKWAKWFLIGSFSVIPFTVSAKTILILGDSLSAGYGINPEQGWVALLQKRLDQQFPKQHKVINASVSGETT
SGALARLPKLLTTYRPNVVVIELGGNDALRGQPPQMIQSNLEKLIQHSQKAKSKVVVFGMKIPPNYGTAYSQAFENNYKV
VSQTYQVKLLPFFLDGVAGHKSLMQNDQIHPNAKAQSILLNNAYPYIKGAL

Specific function: Favors the hydrolysis of several arylesters [H]

COG id: COG2755

COG function: function code E; Lysophospholipase L1 and related esterases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDSL' lipolytic enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1786702, Length=175, Percent_Identity=40.5714285714286, Blast_Score=143, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR001087
- InterPro:   IPR008265 [H]

Pfam domain/function: PF00657 Lipase_GDSL [H]

EC number: =3.1.1.2 [H]

Molecular weight: Translated: 23380; Mature: 23380

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS01098 LIPASE_GDSL_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLYNMFLDGKWAKWFLIGSFSVIPFTVSAKTILILGDSLSAGYGINPEQGWVALLQKRL
CCCEEEEECCCEEEEEEEECCEEEEEEECCEEEEEEECCCCCCCCCCCCHHHHHHHHHHH
DQQFPKQHKVINASVSGETTSGALARLPKLLTTYRPNVVVIELGGNDALRGQPPQMIQSN
HHHCCHHHCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHH
LEKLIQHSQKAKSKVVVFGMKIPPNYGTAYSQAFENNYKVVSQTYQVKLLPFFLDGVAGH
HHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHCCCEEEEEEEEEEEEHHHHCCHHHH
KSLMQNDQIHPNAKAQSILLNNAYPYIKGAL
HHHHCCCCCCCCCCHHEEEECCCCCEEECCC
>Mature Secondary Structure
MQLYNMFLDGKWAKWFLIGSFSVIPFTVSAKTILILGDSLSAGYGINPEQGWVALLQKRL
CCCEEEEECCCEEEEEEEECCEEEEEEECCEEEEEEECCCCCCCCCCCCHHHHHHHHHHH
DQQFPKQHKVINASVSGETTSGALARLPKLLTTYRPNVVVIELGGNDALRGQPPQMIQSN
HHHCCHHHCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHH
LEKLIQHSQKAKSKVVVFGMKIPPNYGTAYSQAFENNYKVVSQTYQVKLLPFFLDGVAGH
HHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHCCCEEEEEEEEEEEEHHHHCCHHHH
KSLMQNDQIHPNAKAQSILLNNAYPYIKGAL
HHHHCCCCCCCCCCHHEEEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8141782 [H]