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The map label for this gene is pta [H]

Identifier: 50083778

GI number: 50083778

Start: 527524

End: 529686

Strand: Reverse

Name: pta [H]

Synonym: ACIAD0540

Alternate gene names: 50083778

Gene position: 529686-527524 (Counterclockwise)

Preceding gene: 50083779

Following gene: 50083776

Centisome position: 14.72

GC content: 44.85

Gene sequence:

>2163_bases
ATGAATACAATTTTAATGATCCCGACTGGCGAAGGTGTCGGGTTAACTTCAGCCTGTCTTGGGCTGATTTATGCACTCGA
TTGTAATGGAATTAAAGCAGGTTTTTTAAAGCCATTTTCACAAGAACTTCCCAATCAGGTTGATCGTACGACCTCACTGT
TTAGCCATCTTTTTCAAGGCAAGACAGTAACTTCTATTTCACACGAAAAAGTATTGCAACGTCTTGCTTTGGGCGAACGA
GATGAGCTTCTTGAAGAAGCCGTGAGTATTCATCGTAATGTTGCGGCAAATTATGATGTGATTATTGTGGAGGGTTTACT
TCCAAACGCACAGGATCATTTTGCGACAGAACTCAATGCTGCACTCGCACAAGCACTAGATGCCAAAGTCGTTTTGGTTA
GTACTGCCGATGTTCAAAACCCACGCCGTACTGCGGAAAAAATTGAAGCTCACCTGCATCACTTTGGTGGAGTTTCATCC
AATCGTACCGCAGGTGTGCTTTTTATGCGTACACGAGGCTTACCTGAAGAAACGGCACAAATCCCGCTTACTATAGATCC
ATCACTCCGCCTCAATACAGAGATTGCAGCTTTTAGCCAAGAATTGCAGCGCTATAACCGTAATCTGGGTACAACCACCC
TACCGATCATTGGTTTAGTGCCTTTTAGCAATACCTTGAGCGTCCCACGCACACTGGATATTGCATCCATCATTGAGGGA
GACTGGATTCATCAAGGTGAAGCCAGACATCGTCGTATCCTGCACTCTAGTCTGATCGCCTCGAGTATCGAATATGAACT
GAACAAATTTGTTGCAGGTGAACTGATCATCAGCGCATCTGAGCGAACTGATGTCTTGTTGGCCAGTAGTCTCGCTACAA
GCAATGGTATTCCACTGGCTGGTCTTGTCCTGACTGAACGTAAAGCACCTAATCCACAAATTTTGGATTTCTGTCAGCAT
GCCATCAAGCAGGGCTTACCTATTTTACATACACAGCTCAATACATTAGAAACTGCGCAGCGTCTTGCAGATTTTGGCAA
TGAAATTCCAGTGGATGATACCGAACGTGCGGAACAAGTGACTCGCTTTGTTTCGAGTCATATCGACACTGCATGGCTCA
ACTCACAAATCAATACTGGTGTGCAGCCGCGCTTATCTCCGTCTGCATTTCGTCATGAGTTGGTGCAAAAATCAATTGCA
GCAAAAAAACGTATTGTACTTCCCGAAGGTGATGAGCCTCGGACAGTACAAGCTGCAGCAATCTGCCAATCACGTGGTAT
TGCTCATTGTATCTTGCTTGCAAAACCTGAAGCTGTGGTAGAAGTAGCCAAAGCACGGGGTATCGAGCTGCCTGATGATC
TGGAAATCATTGATCCAGATCTAATTCGTAACCAATACATCACACCGATGGTTGAGCTACGTAATGGCAAACTTAACGAA
TTACAAGCCAAAGAACAGCTACAAGATACCGTCGTTTTGGGTACCATGATGCTCGCACTTGATCAGGTGGATGGTTTGGT
TTCAGGTGCCATTCATACCACAGCAAATACGGTACGCCCTGCATTTCAACTGATTAAAACAGCACCTGATTACTCATTGG
TTTCATCAGTTTTCTTTATGTTGTTGCCAGATGAAGTATATGTATATGGTGACTGCGCAATCAATCCAGATCCAGATGCC
GACCAACTGGCCGAAATTGCAATTCAGTCTGCAGATTCAGCTAAAGCCTTTGGAATTAACCCTCGCATTGCAATGATCAG
TTATTCTACTGGTACTTCTGGTGCAGGAGCAGATGTAGAGAAAGTTGCCAAAGCAACTGAAATTGCCAAACAGCGTCGTC
CAGATTTATTGATCGATGGCCCATTACAATACGATGCAGCCTCGGTAGAAAGTGTAGGCCGACAAAAAGCACCAGACTCT
CAAGTTGCTGGACGGGCAAACGTCTTTATTTTCCCAGACTTAAATACAGGGAATACGACTTATAAAGCGGTTCAACGCTC
TGCCAATGTTGTGAGTGTGGGTCCAATGCTGCAAGGCTTGAATAAACCCGTAAATGATCTGTCTCGTGGTGCATTGGTCG
ATGACATTGTGTTTACCATTGCCTTAACTGCGATTCAGGCCGAACAACAACTTGAAGCCAAAGCTGCTGCGCTAGCGTCA
TAA

Upstream 100 bases:

>100_bases
ACCGAACAGGTGGTTGAACACGCAAAAAAGTCTGAATCAATGGTTAGCTTTACCTAGCCATTGATCTTCAAACCAACATT
GATTATTTGATAAGGCTTTT

Downstream 100 bases:

>100_bases
TCGCTTTTAATCGCTCTCTAAAAAGCCACTTGCCACTATCAAGTGGCTTTTTAAATTGATTGGCAGTATTACTTTTTTCG
AGCCAACCATACCGTATGTC

Product: phosphate acetyltransferase

Products: NA

Alternate protein names: Phosphotransacetylase [H]

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
MNTILMIPTGEGVGLTSACLGLIYALDCNGIKAGFLKPFSQELPNQVDRTTSLFSHLFQGKTVTSISHEKVLQRLALGER
DELLEEAVSIHRNVAANYDVIIVEGLLPNAQDHFATELNAALAQALDAKVVLVSTADVQNPRRTAEKIEAHLHHFGGVSS
NRTAGVLFMRTRGLPEETAQIPLTIDPSLRLNTEIAAFSQELQRYNRNLGTTTLPIIGLVPFSNTLSVPRTLDIASIIEG
DWIHQGEARHRRILHSSLIASSIEYELNKFVAGELIISASERTDVLLASSLATSNGIPLAGLVLTERKAPNPQILDFCQH
AIKQGLPILHTQLNTLETAQRLADFGNEIPVDDTERAEQVTRFVSSHIDTAWLNSQINTGVQPRLSPSAFRHELVQKSIA
AKKRIVLPEGDEPRTVQAAAICQSRGIAHCILLAKPEAVVEVAKARGIELPDDLEIIDPDLIRNQYITPMVELRNGKLNE
LQAKEQLQDTVVLGTMMLALDQVDGLVSGAIHTTANTVRPAFQLIKTAPDYSLVSSVFFMLLPDEVYVYGDCAINPDPDA
DQLAEIAIQSADSAKAFGINPRIAMISYSTGTSGAGADVEKVAKATEIAKQRRPDLLIDGPLQYDAASVESVGRQKAPDS
QVAGRANVFIFPDLNTGNTTYKAVQRSANVVSVGPMLQGLNKPVNDLSRGALVDDIVFTIALTAIQAEQQLEAKAAALAS

Sequences:

>Translated_720_residues
MNTILMIPTGEGVGLTSACLGLIYALDCNGIKAGFLKPFSQELPNQVDRTTSLFSHLFQGKTVTSISHEKVLQRLALGER
DELLEEAVSIHRNVAANYDVIIVEGLLPNAQDHFATELNAALAQALDAKVVLVSTADVQNPRRTAEKIEAHLHHFGGVSS
NRTAGVLFMRTRGLPEETAQIPLTIDPSLRLNTEIAAFSQELQRYNRNLGTTTLPIIGLVPFSNTLSVPRTLDIASIIEG
DWIHQGEARHRRILHSSLIASSIEYELNKFVAGELIISASERTDVLLASSLATSNGIPLAGLVLTERKAPNPQILDFCQH
AIKQGLPILHTQLNTLETAQRLADFGNEIPVDDTERAEQVTRFVSSHIDTAWLNSQINTGVQPRLSPSAFRHELVQKSIA
AKKRIVLPEGDEPRTVQAAAICQSRGIAHCILLAKPEAVVEVAKARGIELPDDLEIIDPDLIRNQYITPMVELRNGKLNE
LQAKEQLQDTVVLGTMMLALDQVDGLVSGAIHTTANTVRPAFQLIKTAPDYSLVSSVFFMLLPDEVYVYGDCAINPDPDA
DQLAEIAIQSADSAKAFGINPRIAMISYSTGTSGAGADVEKVAKATEIAKQRRPDLLIDGPLQYDAASVESVGRQKAPDS
QVAGRANVFIFPDLNTGNTTYKAVQRSANVVSVGPMLQGLNKPVNDLSRGALVDDIVFTIALTAIQAEQQLEAKAAALAS
>Mature_720_residues
MNTILMIPTGEGVGLTSACLGLIYALDCNGIKAGFLKPFSQELPNQVDRTTSLFSHLFQGKTVTSISHEKVLQRLALGER
DELLEEAVSIHRNVAANYDVIIVEGLLPNAQDHFATELNAALAQALDAKVVLVSTADVQNPRRTAEKIEAHLHHFGGVSS
NRTAGVLFMRTRGLPEETAQIPLTIDPSLRLNTEIAAFSQELQRYNRNLGTTTLPIIGLVPFSNTLSVPRTLDIASIIEG
DWIHQGEARHRRILHSSLIASSIEYELNKFVAGELIISASERTDVLLASSLATSNGIPLAGLVLTERKAPNPQILDFCQH
AIKQGLPILHTQLNTLETAQRLADFGNEIPVDDTERAEQVTRFVSSHIDTAWLNSQINTGVQPRLSPSAFRHELVQKSIA
AKKRIVLPEGDEPRTVQAAAICQSRGIAHCILLAKPEAVVEVAKARGIELPDDLEIIDPDLIRNQYITPMVELRNGKLNE
LQAKEQLQDTVVLGTMMLALDQVDGLVSGAIHTTANTVRPAFQLIKTAPDYSLVSSVFFMLLPDEVYVYGDCAINPDPDA
DQLAEIAIQSADSAKAFGINPRIAMISYSTGTSGAGADVEKVAKATEIAKQRRPDLLIDGPLQYDAASVESVGRQKAPDS
QVAGRANVFIFPDLNTGNTTYKAVQRSANVVSVGPMLQGLNKPVNDLSRGALVDDIVFTIALTAIQAEQQLEAKAAALAS

Specific function: Conversion of acetate to acetyl-CoA; second step. [C]

COG id: COG0280

COG function: function code C; Phosphotransacetylase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788635, Length=718, Percent_Identity=48.8857938718663, Blast_Score=668, Evalue=0.0,
Organism=Escherichia coli, GI1788800, Length=312, Percent_Identity=36.8589743589744, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1788806, Length=334, Percent_Identity=29.940119760479, Blast_Score=155, Evalue=9e-39,

Paralogues:

None

Copy number: 1420 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1250 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010766
- InterPro:   IPR016475
- InterPro:   IPR004614
- InterPro:   IPR002505 [H]

Pfam domain/function: PF07085 DRTGG; PF01515 PTA_PTB [H]

EC number: =2.3.1.8 [H]

Molecular weight: Translated: 77883; Mature: 77883

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTILMIPTGEGVGLTSACLGLIYALDCNGIKAGFLKPFSQELPNQVDRTTSLFSHLFQG
CCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHCCHHHHHCCHHHHHHHHHHHHHHCC
KTVTSISHEKVLQRLALGERDELLEEAVSIHRNVAANYDVIIVEGLLPNAQDHFATELNA
CCEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
ALAQALDAKVVLVSTADVQNPRRTAEKIEAHLHHFGGVSSNRTAGVLFMRTRGLPEETAQ
HHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHCE
IPLTIDPSLRLNTEIAAFSQELQRYNRNLGTTTLPIIGLVPFSNTLSVPRTLDIASIIEG
EEEEECCCCEECHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHCC
DWIHQGEARHRRILHSSLIASSIEYELNKFVAGELIISASERTDVLLASSLATSNGIPLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEHHHHCCCCCCEE
GLVLTERKAPNPQILDFCQHAIKQGLPILHTQLNTLETAQRLADFGNEIPVDDTERAEQV
EEEEECCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
TRFVSSHIDTAWLNSQINTGVQPRLSPSAFRHELVQKSIAAKKRIVLPEGDEPRTVQAAA
HHHHHHHCCHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCEEECCCCCCCCHHHHHH
ICQSRGIAHCILLAKPEAVVEVAKARGIELPDDLEIIDPDLIRNQYITPMVELRNGKLNE
HHHHCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCHHHEECCCCCHH
LQAKEQLQDTVVLGTMMLALDQVDGLVSGAIHTTANTVRPAFQLIKTAPDYSLVSSVFFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LLPDEVYVYGDCAINPDPDADQLAEIAIQSADSAKAFGINPRIAMISYSTGTSGAGADVE
HCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCEECCCCEEEEEEECCCCCCCCCCHH
KVAKATEIAKQRRPDLLIDGPLQYDAASVESVGRQKAPDSQVAGRANVFIFPDLNTGNTT
HHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCCCCHHCCCCCEEEEEECCCCCCHH
YKAVQRSANVVSVGPMLQGLNKPVNDLSRGALVDDIVFTIALTAIQAEQQLEAKAAALAS
HHHHHHCCCEEEECHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTILMIPTGEGVGLTSACLGLIYALDCNGIKAGFLKPFSQELPNQVDRTTSLFSHLFQG
CCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHCCHHHHHCCHHHHHHHHHHHHHHCC
KTVTSISHEKVLQRLALGERDELLEEAVSIHRNVAANYDVIIVEGLLPNAQDHFATELNA
CCEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
ALAQALDAKVVLVSTADVQNPRRTAEKIEAHLHHFGGVSSNRTAGVLFMRTRGLPEETAQ
HHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHCE
IPLTIDPSLRLNTEIAAFSQELQRYNRNLGTTTLPIIGLVPFSNTLSVPRTLDIASIIEG
EEEEECCCCEECHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHCC
DWIHQGEARHRRILHSSLIASSIEYELNKFVAGELIISASERTDVLLASSLATSNGIPLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEHHHHCCCCCCEE
GLVLTERKAPNPQILDFCQHAIKQGLPILHTQLNTLETAQRLADFGNEIPVDDTERAEQV
EEEEECCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
TRFVSSHIDTAWLNSQINTGVQPRLSPSAFRHELVQKSIAAKKRIVLPEGDEPRTVQAAA
HHHHHHHCCHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCEEECCCCCCCCHHHHHH
ICQSRGIAHCILLAKPEAVVEVAKARGIELPDDLEIIDPDLIRNQYITPMVELRNGKLNE
HHHHCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCHHHEECCCCCHH
LQAKEQLQDTVVLGTMMLALDQVDGLVSGAIHTTANTVRPAFQLIKTAPDYSLVSSVFFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LLPDEVYVYGDCAINPDPDADQLAEIAIQSADSAKAFGINPRIAMISYSTGTSGAGADVE
HCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCEECCCCEEEEEEECCCCCCCCCCHH
KVAKATEIAKQRRPDLLIDGPLQYDAASVESVGRQKAPDSQVAGRANVFIFPDLNTGNTT
HHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCCCCHHCCCCCEEEEEECCCCCCHH
YKAVQRSANVVSVGPMLQGLNKPVNDLSRGALVDDIVFTIALTAIQAEQQLEAKAAALAS
HHHHHHCCCEEEECHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883769; 7918659; 9205837; 9278503; 2536666 [H]