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The map label for this gene is lnt [H]

Identifier: 50083670

GI number: 50083670

Start: 416095

End: 417654

Strand: Reverse

Name: lnt [H]

Synonym: ACIAD0415

Alternate gene names: 50083670

Gene position: 417654-416095 (Counterclockwise)

Preceding gene: 50083671

Following gene: 50083665

Centisome position: 11.61

GC content: 43.91

Gene sequence:

>1560_bases
ATGAGAGCATACTTTGAGCAGCTGTTAGGCAATTCCCGACAGCAAAAACAGCTTCCTTTTATTTTTCCTTTTTTAATTTC
GCTATGTTCTGGCGCAATATTTAGTCTCGCTTTAGCACCTTATTATTATTGGTGGATTGCGATTTTATCTCCAGCTCTGC
TTTATGCCGTATTACATCGTCGCTCAGCCAAACAGGCATTTATGCTGGGTTGGGCCTATGGGCTGGGATTATGGTTTGTC
GGGGCTTTCTGGCTTTATACTTCCATTCATGTATATGGCGATACCAATGCCATTCTCAGTGTGTTGATGATTGCGATTAT
GGCACTGGTGATGGGCTTATTTACTGCCATCCAAACCTGGTTTTACCGCCGCTTTTTTCCCGAAACGCCTTTAACTTTTG
CGCCCATCTGGATTGTCTTTGAATGGGCAAAAACTTGGGTGTTTACAGGATTTCCGTGGTTATTTGCGGGTTATGCATTC
ACCGAGCGTTTTTTAGATCACTATGCACCTTTGTTTGGTGTATTCGGTGTTTCCTTTGTGGTTATTACCTTAGCTTGTGC
TTTGGTTGAAATCATCAAAGGGCGTATTTTCTGGCTCATTCCATCGGGTCTGCTGCTGCTCGGTGCTTGGGGTGCATCCC
ATTTACAATTTGTGCAACCCAAGAAAGCGCCTCCACTTTCTGTTTCATTAATTCAGGGCAATATTCCACAAGATTTAAAA
TGGCTGACCGAATATCAATTTAAAACGCTCATGATTTATGCCAATTTGACGCGTTCAGAATGGGGACGAGACCTGATTGT
CTGGCCTGAATCTTCAATTCCAATGTTTCAAACCGATATTCAACCTTTTCTAGATGCCATGAACCAACAGGCAAAAAATC
GAGGTTCGGCATGGGTCACTGGCATTCCTTATTGGGATGTTACAGGTTCGCGGGAAGTGGGGACGCCACTCTATTATAAT
AGCATCATGGCTTCTGGCGATAATTCTCAAGGCCTCTATAAAAAACAGCGTTTGGTTCCGTTTGGCGAATATATTCCGTT
GTCTGGTCTATTAAGTTGGGTACTACCAGCGTTGCAAAATGATCCGTCTATGAGTGGATTTAGTCAGGGATCAAATAATC
AGAAACCGCTCATGATCAAAGGTCATCGACTTGCTGCTGCCATCTGTTATGAAGTGGCTTATCCAAACCTGACCAGACGC
AACGCAGAAAATAGCGATTTTCTGGTTACGGTATCTAACGATGCTTGGTTTACGGGTACGGCTGGCCCAATGCAACATTT
ACAGATGGTGCAAATGCGGGCCAAAGAAAATGGACGCTGGTTTATCCGTGCCACCAATACTGGAGTGACTGCATTTATTG
ATAGCCAAGGTCATATTGTGAAACAAGCACCTATTGATAAAGAAGCTGTTTTACGTGGCGACTTACCTGCAATGCAGGGT
GAAACCTTATACACCCGTTTAAGTGACTGGCCGATCTTACTGTTTTCGGTTCTATTGCTGATTCTGGGCTGGATCTATCG
TCCACGTCAGGTCGATGTGTCATTTAAATCACGTCGCTAA

Upstream 100 bases:

>100_bases
TGAGTGACCTACAAGGTCAGGTGATCGAACTGGATGACTGGCAATTTACAATTATTGAAGCAGATGCACGCACTATTCAT
CTGATTCGAGCTGTACATAA

Downstream 100 bases:

>100_bases
TTGCTAAATGTGTCGGGCTTTTAAAACCGAGATGGTTCACCCATCTCGGTTTTTTTATACATGTTGATGAGTTAAATTCA
TTTTTTTAGGGAAATTCCCC

Product: apolipoprotein N-acyltransferase, copper homeostasis protein

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MRAYFEQLLGNSRQQKQLPFIFPFLISLCSGAIFSLALAPYYYWWIAILSPALLYAVLHRRSAKQAFMLGWAYGLGLWFV
GAFWLYTSIHVYGDTNAILSVLMIAIMALVMGLFTAIQTWFYRRFFPETPLTFAPIWIVFEWAKTWVFTGFPWLFAGYAF
TERFLDHYAPLFGVFGVSFVVITLACALVEIIKGRIFWLIPSGLLLLGAWGASHLQFVQPKKAPPLSVSLIQGNIPQDLK
WLTEYQFKTLMIYANLTRSEWGRDLIVWPESSIPMFQTDIQPFLDAMNQQAKNRGSAWVTGIPYWDVTGSREVGTPLYYN
SIMASGDNSQGLYKKQRLVPFGEYIPLSGLLSWVLPALQNDPSMSGFSQGSNNQKPLMIKGHRLAAAICYEVAYPNLTRR
NAENSDFLVTVSNDAWFTGTAGPMQHLQMVQMRAKENGRWFIRATNTGVTAFIDSQGHIVKQAPIDKEAVLRGDLPAMQG
ETLYTRLSDWPILLFSVLLLILGWIYRPRQVDVSFKSRR

Sequences:

>Translated_519_residues
MRAYFEQLLGNSRQQKQLPFIFPFLISLCSGAIFSLALAPYYYWWIAILSPALLYAVLHRRSAKQAFMLGWAYGLGLWFV
GAFWLYTSIHVYGDTNAILSVLMIAIMALVMGLFTAIQTWFYRRFFPETPLTFAPIWIVFEWAKTWVFTGFPWLFAGYAF
TERFLDHYAPLFGVFGVSFVVITLACALVEIIKGRIFWLIPSGLLLLGAWGASHLQFVQPKKAPPLSVSLIQGNIPQDLK
WLTEYQFKTLMIYANLTRSEWGRDLIVWPESSIPMFQTDIQPFLDAMNQQAKNRGSAWVTGIPYWDVTGSREVGTPLYYN
SIMASGDNSQGLYKKQRLVPFGEYIPLSGLLSWVLPALQNDPSMSGFSQGSNNQKPLMIKGHRLAAAICYEVAYPNLTRR
NAENSDFLVTVSNDAWFTGTAGPMQHLQMVQMRAKENGRWFIRATNTGVTAFIDSQGHIVKQAPIDKEAVLRGDLPAMQG
ETLYTRLSDWPILLFSVLLLILGWIYRPRQVDVSFKSRR
>Mature_519_residues
MRAYFEQLLGNSRQQKQLPFIFPFLISLCSGAIFSLALAPYYYWWIAILSPALLYAVLHRRSAKQAFMLGWAYGLGLWFV
GAFWLYTSIHVYGDTNAILSVLMIAIMALVMGLFTAIQTWFYRRFFPETPLTFAPIWIVFEWAKTWVFTGFPWLFAGYAF
TERFLDHYAPLFGVFGVSFVVITLACALVEIIKGRIFWLIPSGLLLLGAWGASHLQFVQPKKAPPLSVSLIQGNIPQDLK
WLTEYQFKTLMIYANLTRSEWGRDLIVWPESSIPMFQTDIQPFLDAMNQQAKNRGSAWVTGIPYWDVTGSREVGTPLYYN
SIMASGDNSQGLYKKQRLVPFGEYIPLSGLLSWVLPALQNDPSMSGFSQGSNNQKPLMIKGHRLAAAICYEVAYPNLTRR
NAENSDFLVTVSNDAWFTGTAGPMQHLQMVQMRAKENGRWFIRATNTGVTAFIDSQGHIVKQAPIDKEAVLRGDLPAMQG
ETLYTRLSDWPILLFSVLLLILGWIYRPRQVDVSFKSRR

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=489, Percent_Identity=34.560327198364, Blast_Score=269, Evalue=3e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 59046; Mature: 59046

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAYFEQLLGNSRQQKQLPFIFPFLISLCSGAIFSLALAPYYYWWIAILSPALLYAVLHR
CHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSAKQAFMLGWAYGLGLWFVGAFWLYTSIHVYGDTNAILSVLMIAIMALVMGLFTAIQTW
HCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
FYRRFFPETPLTFAPIWIVFEWAKTWVFTGFPWLFAGYAFTERFLDHYAPLFGVFGVSFV
HHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VITLACALVEIIKGRIFWLIPSGLLLLGAWGASHLQFVQPKKAPPLSVSLIQGNIPQDLK
HHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCHHEEECCCCCCCCEEEEEECCCCHHHH
WLTEYQFKTLMIYANLTRSEWGRDLIVWPESSIPMFQTDIQPFLDAMNQQAKNRGSAWVT
HHHHHHHEEEEEEEECCHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEE
GIPYWDVTGSREVGTPLYYNSIMASGDNSQGLYKKQRLVPFGEYIPLSGLLSWVLPALQN
ECCEECCCCCCCCCCCHHHHHHEECCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCC
DPSMSGFSQGSNNQKPLMIKGHRLAAAICYEVAYPNLTRRNAENSDFLVTVSNDAWFTGT
CCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEECCC
AGPMQHLQMVQMRAKENGRWFIRATNTGVTAFIDSQGHIVKQAPIDKEAVLRGDLPAMQG
CCHHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCEEECCCCCHHHHHCCCCCCCCC
ETLYTRLSDWPILLFSVLLLILGWIYRPRQVDVSFKSRR
CHHHHHHCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCC
>Mature Secondary Structure
MRAYFEQLLGNSRQQKQLPFIFPFLISLCSGAIFSLALAPYYYWWIAILSPALLYAVLHR
CHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSAKQAFMLGWAYGLGLWFVGAFWLYTSIHVYGDTNAILSVLMIAIMALVMGLFTAIQTW
HCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
FYRRFFPETPLTFAPIWIVFEWAKTWVFTGFPWLFAGYAFTERFLDHYAPLFGVFGVSFV
HHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VITLACALVEIIKGRIFWLIPSGLLLLGAWGASHLQFVQPKKAPPLSVSLIQGNIPQDLK
HHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCHHEEECCCCCCCCEEEEEECCCCHHHH
WLTEYQFKTLMIYANLTRSEWGRDLIVWPESSIPMFQTDIQPFLDAMNQQAKNRGSAWVT
HHHHHHHEEEEEEEECCHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEE
GIPYWDVTGSREVGTPLYYNSIMASGDNSQGLYKKQRLVPFGEYIPLSGLLSWVLPALQN
ECCEECCCCCCCCCCCHHHHHHEECCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCC
DPSMSGFSQGSNNQKPLMIKGHRLAAAICYEVAYPNLTRRNAENSDFLVTVSNDAWFTGT
CCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEECCC
AGPMQHLQMVQMRAKENGRWFIRATNTGVTAFIDSQGHIVKQAPIDKEAVLRGDLPAMQG
CCHHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCEEECCCCCHHHHHCCCCCCCCC
ETLYTRLSDWPILLFSVLLLILGWIYRPRQVDVSFKSRR
CHHHHHHCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA