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The map label for this gene is ribC [H]

Identifier: 50083527

GI number: 50083527

Start: 249084

End: 249743

Strand: Direct

Name: ribC [H]

Synonym: ACIAD0249

Alternate gene names: 50083527

Gene position: 249084-249743 (Clockwise)

Preceding gene: 50083526

Following gene: 50083532

Centisome position: 6.92

GC content: 43.94

Gene sequence:

>660_bases
ATGTTTACAGGCATTATTGAAAGTTTAGGTCAGGTTGAAAGCCTCCAGAGTGTTGGCGGTGATGTACGTTTGCGTATTCA
GACTGATCTGGATATGTCTGATGTACATTTAGGCGATTCAATTGCTACCAATGGTATTTGCCTGACTGTGATTGAATGGG
GTAAAAACTGGTATGCAGCAGACGTTTCACGTGAAAGTTTAAATCGAACGACATTGGGTCAATGGAAAGTGGGGCAACCC
GTGAATGTTGAAAAAGCCATGTTACCTACGACACGTTTTGGCGGGCATATTGTCAGCGGGCATGTCGATGCTGTCGGTGA
GATTACCTTAGTCCGAGAAGATGCGCGTTCAATCTACTATGAAGTCACTGCGCCTGCCGAAATTGCAAAATATCTGGCAG
AGAAGGGCTCGGTAACGGTGGATGGCATTAGTCTGACCATTAACCATTTACGCGGCAATATCTTGAGCCTGAATCTGATC
CCGCATACTGCTGAACGTACCAACATTTCGACATGGAAAACGGGAAGTAAGGTGAATCTTGAAGTGGATGTATTGGCGCG
TTATATCGAACGTTTATTACTCGGTGATAAAGCGGCTGAACAAAACCCAAAATCTGAGATCAGCATGAGCTTTCTAGCAG
AAAATGGATTTTTAAAATAA

Upstream 100 bases:

>100_bases
CTGAACTGGGTGGTGTTGATACTTCTGGGAATAGCACCCAGCTTGCGCTGTGGTAGTTACCGTCTGGTATTGTATTGTGT
AGGAATTTGGAGAGATCAAC

Downstream 100 bases:

>100_bases
TAGTGTAAAAAGCTCATCTAAAAGATGAGCTTTTTTCTATGTATGTTTTAGTCTTTGACCACGGTCAGTGATGTTGTCCC
CAGCCAAGGTTTGATGGCTT

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MFTGIIESLGQVESLQSVGGDVRLRIQTDLDMSDVHLGDSIATNGICLTVIEWGKNWYAADVSRESLNRTTLGQWKVGQP
VNVEKAMLPTTRFGGHIVSGHVDAVGEITLVREDARSIYYEVTAPAEIAKYLAEKGSVTVDGISLTINHLRGNILSLNLI
PHTAERTNISTWKTGSKVNLEVDVLARYIERLLLGDKAAEQNPKSEISMSFLAENGFLK

Sequences:

>Translated_219_residues
MFTGIIESLGQVESLQSVGGDVRLRIQTDLDMSDVHLGDSIATNGICLTVIEWGKNWYAADVSRESLNRTTLGQWKVGQP
VNVEKAMLPTTRFGGHIVSGHVDAVGEITLVREDARSIYYEVTAPAEIAKYLAEKGSVTVDGISLTINHLRGNILSLNLI
PHTAERTNISTWKTGSKVNLEVDVLARYIERLLLGDKAAEQNPKSEISMSFLAENGFLK
>Mature_219_residues
MFTGIIESLGQVESLQSVGGDVRLRIQTDLDMSDVHLGDSIATNGICLTVIEWGKNWYAADVSRESLNRTTLGQWKVGQP
VNVEKAMLPTTRFGGHIVSGHVDAVGEITLVREDARSIYYEVTAPAEIAKYLAEKGSVTVDGISLTINHLRGNILSLNLI
PHTAERTNISTWKTGSKVNLEVDVLARYIERLLLGDKAAEQNPKSEISMSFLAENGFLK

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=214, Percent_Identity=34.5794392523364, Blast_Score=119, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319733, Length=206, Percent_Identity=36.8932038834951, Blast_Score=132, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 23981; Mature: 23981

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIIESLGQVESLQSVGGDVRLRIQTDLDMSDVHLGDSIATNGICLTVIEWGKNWYAA
CCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEECCCCCCCCCEEEEEEECCCCEEEE
DVSRESLNRTTLGQWKVGQPVNVEKAMLPTTRFGGHIVSGHVDAVGEITLVREDARSIYY
CCCHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEECCCCCCEEEEEEEECCCEEEE
EVTAPAEIAKYLAEKGSVTVDGISLTINHLRGNILSLNLIPHTAERTNISTWKTGSKVNL
EEECHHHHHHHHHHCCCEEEEEEEEEEECCCCCEEEEEECCCCCCCCCCCEECCCCEEEE
EVDVLARYIERLLLGDKAAEQNPKSEISMSFLAENGFLK
EHHHHHHHHHHHHHCCCCCCCCCHHHHHHEEEECCCCCC
>Mature Secondary Structure
MFTGIIESLGQVESLQSVGGDVRLRIQTDLDMSDVHLGDSIATNGICLTVIEWGKNWYAA
CCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEECCCCCCCCCEEEEEEECCCCEEEE
DVSRESLNRTTLGQWKVGQPVNVEKAMLPTTRFGGHIVSGHVDAVGEITLVREDARSIYY
CCCHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEECCCCCCEEEEEEEECCCEEEE
EVTAPAEIAKYLAEKGSVTVDGISLTINHLRGNILSLNLIPHTAERTNISTWKTGSKVNL
EEECHHHHHHHHHHCCCEEEEEEEEEEECCCCCEEEEEECCCCCCCCCCCEECCCCEEEE
EVDVLARYIERLLLGDKAAEQNPKSEISMSFLAENGFLK
EHHHHHHHHHHHHHCCCCCCCCCHHHHHHEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]