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The map label for this gene is kdgD [C]

Identifier: 50083418

GI number: 50083418

Start: 134254

End: 135165

Strand: Direct

Name: kdgD [C]

Synonym: ACIAD0130

Alternate gene names: 50083418

Gene position: 134254-135165 (Clockwise)

Preceding gene: 50083417

Following gene: 50083419

Centisome position: 3.73

GC content: 40.68

Gene sequence:

>912_bases
ATGGATGCTCTTGAATTAAAAAATATTGTTTCTGATGGTTTACTCTCATTTCCAGTGACCGATTTTGACCAAAATGGTGA
CTTTAATGCTGCATCTTATGCAAAACGTCTCGAATGGCTGGCTCCGTATGGTGCAAGTGCATTATTTGCTGCGGGTGGAA
CAGGTGAGTTTTTCTCACTAACGGGTGATGAATATTCAGATGTCATTAAAACTGCAGTCGATGCTTGTAAAGGAAGTGTT
CCTATTATTGCAGGTGCGGGTGGACCAACCCGTCAGGCAATTTTACAGGCTCAAGAAGCTGAACGTTTAGGTGCACATGG
TATTTTATTAATGCCTCATTACTTGACAGAAGCGAGTCAGGAAGGTTTGGTTGAGCACGTAAAGCAAGTTTGTAATGCAG
TCAATTTTGGCGTGATTTTTTATAATCGAAGCGTGTCTAAGCTCAATGTTGATTCCTTACAGCAACTTGTTGAAAGTTGT
CCAAATCTAATCGGTTTTAAAGACAGTTCTGGTCAGATTGATATGATGACAGAAGTCGTACAAACCTTGGGTGACCGTTT
ATCATATTTAGGTGGTTTACCAACAGCTGAAATTTTTGCTGCACCATACAAGGCTTTGGGTTCACCTGTTTATTCATCTG
CTGTATTCAATTTCATTCCTAAAACAGCGATGGAATTTTACAATGCGCTGCGTAATGATGACTTTGCAACGACACAACGT
TTAATTCGTGACTTCTTTTTACCACTGATCAAAATCCGTAATCGTAAATCTGGTTATGCAGTCAGTATGGTAAAAGCGGG
TGCCAAAATTGTAGGGCATGATGCAGGGCCAGTACGTCCTCCATTAAGCGATCTAACTCCTCAGGATTATGAAGATTTAG
CGGCATTAATTGCAACGCTTGGACCACAGTAA

Upstream 100 bases:

>100_bases
TATAGAAATTTCTATAAAAAGAAAAGAGAAGTAGATTGGAAAACTAAAACATATGATGTAAGATGTCTGACAACAGCAAA
TTATTTATGGAGAACTTGCT

Downstream 100 bases:

>100_bases
ACTCAAACTTCATACAGGTTAGGAAGGCAAAGATGAGCGAGAATAACGGTAAACAGTTTATCAATGGTCAGCGTGTAGCA
GCCAATGCTCCTACCATTGA

Product: 5-dehydro-4-deoxyglucarate dehydratase

Products: NA

Alternate protein names: 5-keto-4-deoxy-glucarate dehydratase; KDGDH

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MDALELKNIVSDGLLSFPVTDFDQNGDFNAASYAKRLEWLAPYGASALFAAGGTGEFFSLTGDEYSDVIKTAVDACKGSV
PIIAGAGGPTRQAILQAQEAERLGAHGILLMPHYLTEASQEGLVEHVKQVCNAVNFGVIFYNRSVSKLNVDSLQQLVESC
PNLIGFKDSSGQIDMMTEVVQTLGDRLSYLGGLPTAEIFAAPYKALGSPVYSSAVFNFIPKTAMEFYNALRNDDFATTQR
LIRDFFLPLIKIRNRKSGYAVSMVKAGAKIVGHDAGPVRPPLSDLTPQDYEDLAALIATLGPQ

Sequences:

>Translated_303_residues
MDALELKNIVSDGLLSFPVTDFDQNGDFNAASYAKRLEWLAPYGASALFAAGGTGEFFSLTGDEYSDVIKTAVDACKGSV
PIIAGAGGPTRQAILQAQEAERLGAHGILLMPHYLTEASQEGLVEHVKQVCNAVNFGVIFYNRSVSKLNVDSLQQLVESC
PNLIGFKDSSGQIDMMTEVVQTLGDRLSYLGGLPTAEIFAAPYKALGSPVYSSAVFNFIPKTAMEFYNALRNDDFATTQR
LIRDFFLPLIKIRNRKSGYAVSMVKAGAKIVGHDAGPVRPPLSDLTPQDYEDLAALIATLGPQ
>Mature_303_residues
MDALELKNIVSDGLLSFPVTDFDQNGDFNAASYAKRLEWLAPYGASALFAAGGTGEFFSLTGDEYSDVIKTAVDACKGSV
PIIAGAGGPTRQAILQAQEAERLGAHGILLMPHYLTEASQEGLVEHVKQVCNAVNFGVIFYNRSVSKLNVDSLQQLVESC
PNLIGFKDSSGQIDMMTEVVQTLGDRLSYLGGLPTAEIFAAPYKALGSPVYSSAVFNFIPKTAMEFYNALRNDDFATTQR
LIRDFFLPLIKIRNRKSGYAVSMVKAGAKIVGHDAGPVRPPLSDLTPQDYEDLAALIATLGPQ

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family

Homologues:

Organism=Escherichia coli, GI1788823, Length=235, Percent_Identity=28.5106382978723, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786463, Length=221, Percent_Identity=26.6968325791855, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082415, Length=260, Percent_Identity=26.1538461538462, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): KDGD_ACIAD (Q6FFQ1)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_044928.1
- ProteinModelPortal:   Q6FFQ1
- STRING:   Q6FFQ1
- GeneID:   2879972
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0130
- NMPDR:   fig|62977.3.peg.102
- eggNOG:   COG0329
- HOGENOM:   HBG358848
- OMA:   RNRKKGY
- ProtClustDB:   PRK03620
- BioCyc:   ASP62977:ACIAD0130-MONOMER
- BioCyc:   MetaCyc:MONOMER-15625
- HAMAP:   MF_00694
- InterPro:   IPR013785
- InterPro:   IPR017655
- InterPro:   IPR002220
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR12128
- PRINTS:   PR00146
- TIGRFAMs:   TIGR03249

Pfam domain/function: PF00701 DHDPS

EC number: =4.2.1.41

Molecular weight: Translated: 32624; Mature: 32624

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALELKNIVSDGLLSFPVTDFDQNGDFNAASYAKRLEWLAPYGASALFAAGGTGEFFSL
CCHHHHHHHHHCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCEEEE
TGDEYSDVIKTAVDACKGSVPIIAGAGGPTRQAILQAQEAERLGAHGILLMPHYLTEASQ
CCHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHH
EGLVEHVKQVCNAVNFGVIFYNRSVSKLNVDSLQQLVESCPNLIGFKDSSGQIDMMTEVV
HHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCHHHCCCCCCCCCHHHHHHHH
QTLGDRLSYLGGLPTAEIFAAPYKALGSPVYSSAVFNFIPKTAMEFYNALRNDDFATTQR
HHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LIRDFFLPLIKIRNRKSGYAVSMVKAGAKIVGHDAGPVRPPLSDLTPQDYEDLAALIATL
HHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
GPQ
CCC
>Mature Secondary Structure
MDALELKNIVSDGLLSFPVTDFDQNGDFNAASYAKRLEWLAPYGASALFAAGGTGEFFSL
CCHHHHHHHHHCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCEEEE
TGDEYSDVIKTAVDACKGSVPIIAGAGGPTRQAILQAQEAERLGAHGILLMPHYLTEASQ
CCHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHH
EGLVEHVKQVCNAVNFGVIFYNRSVSKLNVDSLQQLVESCPNLIGFKDSSGQIDMMTEVV
HHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCHHHCCCCCCCCCHHHHHHHH
QTLGDRLSYLGGLPTAEIFAAPYKALGSPVYSSAVFNFIPKTAMEFYNALRNDDFATTQR
HHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LIRDFFLPLIKIRNRKSGYAVSMVKAGAKIVGHDAGPVRPPLSDLTPQDYEDLAALIATL
HHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
GPQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA