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The map label for this gene is fimB [H]

Identifier: 50083412

GI number: 50083412

Start: 125975

End: 126712

Strand: Direct

Name: fimB [H]

Synonym: ACIAD0123

Alternate gene names: 50083412

Gene position: 125975-126712 (Clockwise)

Preceding gene: 50083411

Following gene: 50083413

Centisome position: 3.5

GC content: 33.06

Gene sequence:

>738_bases
ATGAAGTTAGTTCTTTTTACTTTGATTATATGCTTGGGTTTATGGGGAGTCCCTGCAATTGCAGGCATACTTCCTGAAAA
TACGCGTGTGATTTTTGATGGGACTGCTTCATCGCGGTCATTTATTGTCGCCAATCAAAATCCGTATCCTATTTTGGTTC
AAACTTGGGTCGATCATGGTTTAGGTGACCCAGATCACGATCAAGCACCTTTCGTAATAAATCCTCCAATATTCAAAATG
CAGCCAGATGCCATTCAAGTTCTAAAAATTATTTATACAGGCGATCAAAAACAGACCGATTTTGAATCACAGTTTTGGCT
AAATTTATATGAAATCCCAGGAAAGAAAAAACTACAATCTAATCAAAAGCCAGAAACTAATCATCAATTAGATTTGTCTA
TTCAAACACAACTCAAAGTCTTTTATCGACCTGCAAAAATTCTGAAAATGAATATTGAAGAGATTGCAAAGCAACTGAAA
TTCAATTTTAAGAAAATTGATAATCAAATTTATCTCATATGTGAGAATCCAACGCCGTATTTTATTTCATTCTCAAAGAT
TGCTCTTATTTCGAATAAAAATTCTGTTTTTATTGAAGATTATCTCGATCAAATGGTCGCACCAAATGCTGATCAAATTT
ACCCTATCAAATATAGGATTGATGATCTGAAATACATTGAATTTAGTGTGATCGCAGAGGATGGTTTTGCATATTCGTTT
AAATATGACTATTATTAA

Upstream 100 bases:

>100_bases
TGTACCGGATTCCTTATCGTGCAGTCCTGAAAAAATTACCTAAAGGTACTGCCACAGCAGGTCGCGTTTATGCCACCGCA
ACCGTGATGGTTAAAATCCA

Downstream 100 bases:

>100_bases
GTTTGGTTAAAATGTGAAGTTAATTAAAATTAACAAATTACTACGTTTTATTACGAACTTAATCTTATAAATAAAGAATG
AATTTTAAAATATGAAGACT

Product: pili assembly chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MKLVLFTLIICLGLWGVPAIAGILPENTRVIFDGTASSRSFIVANQNPYPILVQTWVDHGLGDPDHDQAPFVINPPIFKM
QPDAIQVLKIIYTGDQKQTDFESQFWLNLYEIPGKKKLQSNQKPETNHQLDLSIQTQLKVFYRPAKILKMNIEEIAKQLK
FNFKKIDNQIYLICENPTPYFISFSKIALISNKNSVFIEDYLDQMVAPNADQIYPIKYRIDDLKYIEFSVIAEDGFAYSF
KYDYY

Sequences:

>Translated_245_residues
MKLVLFTLIICLGLWGVPAIAGILPENTRVIFDGTASSRSFIVANQNPYPILVQTWVDHGLGDPDHDQAPFVINPPIFKM
QPDAIQVLKIIYTGDQKQTDFESQFWLNLYEIPGKKKLQSNQKPETNHQLDLSIQTQLKVFYRPAKILKMNIEEIAKQLK
FNFKKIDNQIYLICENPTPYFISFSKIALISNKNSVFIEDYLDQMVAPNADQIYPIKYRIDDLKYIEFSVIAEDGFAYSF
KYDYY
>Mature_245_residues
MKLVLFTLIICLGLWGVPAIAGILPENTRVIFDGTASSRSFIVANQNPYPILVQTWVDHGLGDPDHDQAPFVINPPIFKM
QPDAIQVLKIIYTGDQKQTDFESQFWLNLYEIPGKKKLQSNQKPETNHQLDLSIQTQLKVFYRPAKILKMNIEEIAKQLK
FNFKKIDNQIYLICENPTPYFISFSKIALISNKNSVFIEDYLDQMVAPNADQIYPIKYRIDDLKYIEFSVIAEDGFAYSF
KYDYY

Specific function: Required for the biogenesis of the filamentous hemagglutinin and the fimbria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1789532, Length=187, Percent_Identity=34.7593582887701, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786333, Length=214, Percent_Identity=30.3738317757009, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1790771, Length=204, Percent_Identity=30.3921568627451, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1786743, Length=217, Percent_Identity=27.6497695852535, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1786936, Length=209, Percent_Identity=27.7511961722488, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788428, Length=222, Percent_Identity=29.7297297297297, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787171, Length=184, Percent_Identity=28.2608695652174, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788677, Length=177, Percent_Identity=28.2485875706215, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 28364; Mature: 28364

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVLFTLIICLGLWGVPAIAGILPENTRVIFDGTASSRSFIVANQNPYPILVQTWVDHG
CCHHHHHHHHHHHHHCHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCCCEEEEEEHHCC
LGDPDHDQAPFVINPPIFKMQPDAIQVLKIIYTGDQKQTDFESQFWLNLYEIPGKKKLQS
CCCCCCCCCCEEECCCCEEECCCHHHEEEEEECCCCCCCCCCCEEEEEEEECCCCHHHCC
NQKPETNHQLDLSIQTQLKVFYRPAKILKMNIEEIAKQLKFNFKKIDNQIYLICENPTPY
CCCCCCCCEEEEEEEEEEEEEECCHHHEEECHHHHHHHHHCCCEECCCEEEEEECCCCCE
FISFSKIALISNKNSVFIEDYLDQMVAPNADQIYPIKYRIDDLKYIEFSVIAEDGFAYSF
EEEEEEEEEEECCCCEEHHHHHHHHHCCCCCCEEEEEEEECCEEEEEEEEEECCCEEEEE
KYDYY
EECCC
>Mature Secondary Structure
MKLVLFTLIICLGLWGVPAIAGILPENTRVIFDGTASSRSFIVANQNPYPILVQTWVDHG
CCHHHHHHHHHHHHHCHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCCCEEEEEEHHCC
LGDPDHDQAPFVINPPIFKMQPDAIQVLKIIYTGDQKQTDFESQFWLNLYEIPGKKKLQS
CCCCCCCCCCEEECCCCEEECCCHHHEEEEEECCCCCCCCCCCEEEEEEEECCCCHHHCC
NQKPETNHQLDLSIQTQLKVFYRPAKILKMNIEEIAKQLKFNFKKIDNQIYLICENPTPY
CCCCCCCCEEEEEEEEEEEEEECCHHHEEECHHHHHHHHHCCCEECCCEEEEEECCCCCE
FISFSKIALISNKNSVFIEDYLDQMVAPNADQIYPIKYRIDDLKYIEFSVIAEDGFAYSF
EEEEEEEEEEECCCCEEHHHHHHHHHCCCCCCEEEEEEEECCEEEEEEEEEECCCEEEEE
KYDYY
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1360139; 1354611; 12910271 [H]