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The map label for this gene is lldR [H]

Identifier: 50083397

GI number: 50083397

Start: 107440

End: 108192

Strand: Direct

Name: lldR [H]

Synonym: ACIAD0107

Alternate gene names: 50083397

Gene position: 107440-108192 (Clockwise)

Preceding gene: 50083396

Following gene: 50083398

Centisome position: 2.99

GC content: 49.4

Gene sequence:

>753_bases
ATGAGAGTGTCGGATCAAGTGGTGCAAAAGTTACAGGGCTTAATTGAGCAACGTCACTTAAAACAAGGTGATCGCTTGCC
TGCCGAGCGTCAACTTGCCACCAGCTTGGGAATTTCCCGGCCCTCTCTGCGTGAAGCAATTCAGCAACTCAATAGTCTGG
GGATTCTGGCAAGCCGTCGTGGAGACGGAACCTACATTCAGCAGCTCCCTGAAACATGGTCACAGCAACTGATTGTAGAG
CCGATCAGCAATCTGATTGAAGAAGATCCAGAATACCGCTTTGATGTGCAGGAGGCACGCATTGTGCTGGAGGGCGGTAC
AGCCTGGTACGCGGCACTGCGTTCGACTGAGGCCGATCGTGCCAAGATTCATCAGTGTTTTGATGAAATTGCCTATCATC
AACTACAAGGCGACTCGGCGGCAGCGGCTGTGGCAGACGCCAATTTCCATTTGGCGATTGCCGAAGCATCACACAATCTT
GTGTTGATCCAGATGATGCGAAGCCTATTTGACTTATTGCAATACAACGTCGTTTTAGGACGGAAAAAAGTTTATAACCA
TCCTGTGAGTGCAGATCAGCTGAGTGAGCAGCATTTTCAGGTGATGGATGCGATTGACCGTCAGGATGCACAGGCCGCAC
GTGATGCTGTATGTGGGCATATTGAATTTGTTATCGATCATGTGCGTTCTCTGGATGAAGATGAAGCTCGCCAGAAACGC
GCCACACGTTTACATAGGATTGATCAAACATGA

Upstream 100 bases:

>100_bases
ATAGCATCATATTCACAATCTTTGTGGGCATCATTGTGACGGTTCAGGCGTATATTGTACCTTGGATGATCCCTTAAACT
GGATAGATAAAGGAATAGGT

Downstream 100 bases:

>100_bases
TTATTTCTTCTTCAAATGATTATCGCGAAGCAGCAAAGCGCCGCTTGCCACCATTTCTGTTTCACTATATCGATGGTGGG
GCGTATGCAGAATATACGCT

Product: DNA-binding transcriptional repressor LldR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MRVSDQVVQKLQGLIEQRHLKQGDRLPAERQLATSLGISRPSLREAIQQLNSLGILASRRGDGTYIQQLPETWSQQLIVE
PISNLIEEDPEYRFDVQEARIVLEGGTAWYAALRSTEADRAKIHQCFDEIAYHQLQGDSAAAAVADANFHLAIAEASHNL
VLIQMMRSLFDLLQYNVVLGRKKVYNHPVSADQLSEQHFQVMDAIDRQDAQAARDAVCGHIEFVIDHVRSLDEDEARQKR
ATRLHRIDQT

Sequences:

>Translated_250_residues
MRVSDQVVQKLQGLIEQRHLKQGDRLPAERQLATSLGISRPSLREAIQQLNSLGILASRRGDGTYIQQLPETWSQQLIVE
PISNLIEEDPEYRFDVQEARIVLEGGTAWYAALRSTEADRAKIHQCFDEIAYHQLQGDSAAAAVADANFHLAIAEASHNL
VLIQMMRSLFDLLQYNVVLGRKKVYNHPVSADQLSEQHFQVMDAIDRQDAQAARDAVCGHIEFVIDHVRSLDEDEARQKR
ATRLHRIDQT
>Mature_250_residues
MRVSDQVVQKLQGLIEQRHLKQGDRLPAERQLATSLGISRPSLREAIQQLNSLGILASRRGDGTYIQQLPETWSQQLIVE
PISNLIEEDPEYRFDVQEARIVLEGGTAWYAALRSTEADRAKIHQCFDEIAYHQLQGDSAAAAVADANFHLAIAEASHNL
VLIQMMRSLFDLLQYNVVLGRKKVYNHPVSADQLSEQHFQVMDAIDRQDAQAARDAVCGHIEFVIDHVRSLDEDEARQKR
ATRLHRIDQT

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=243, Percent_Identity=49.3827160493827, Blast_Score=235, Evalue=2e-63,
Organism=Escherichia coli, GI1786303, Length=223, Percent_Identity=35.8744394618834, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789353, Length=225, Percent_Identity=29.7777777777778, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790780, Length=228, Percent_Identity=30.2631578947368, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082208, Length=223, Percent_Identity=28.2511210762332, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789621, Length=228, Percent_Identity=25.4385964912281, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 28340; Mature: 28340

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSDQVVQKLQGLIEQRHLKQGDRLPAERQLATSLGISRPSLREAIQQLNSLGILASRR
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHCCC
GDGTYIQQLPETWSQQLIVEPISNLIEEDPEYRFDVQEARIVLEGGTAWYAALRSTEADR
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCEEEEECCHHHHHHHHCCCHHH
AKIHQCFDEIAYHQLQGDSAAAAVADANFHLAIAEASHNLVLIQMMRSLFDLLQYNVVLG
HHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
RKKVYNHPVSADQLSEQHFQVMDAIDRQDAQAARDAVCGHIEFVIDHVRSLDEDEARQKR
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ATRLHRIDQT
HHHHHHCCCC
>Mature Secondary Structure
MRVSDQVVQKLQGLIEQRHLKQGDRLPAERQLATSLGISRPSLREAIQQLNSLGILASRR
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHCCC
GDGTYIQQLPETWSQQLIVEPISNLIEEDPEYRFDVQEARIVLEGGTAWYAALRSTEADR
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCEEEEECCHHHHHHHHCCCHHH
AKIHQCFDEIAYHQLQGDSAAAAVADANFHLAIAEASHNLVLIQMMRSLFDLLQYNVVLG
HHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
RKKVYNHPVSADQLSEQHFQVMDAIDRQDAQAARDAVCGHIEFVIDHVRSLDEDEARQKR
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ATRLHRIDQT
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]