Click here to switch to the map view.

The map label for this gene is pheA

Identifier: 49478853

GI number: 49478853

Start: 4231087

End: 4231938

Strand: Reverse

Name: pheA

Synonym: BT9727_4168

Alternate gene names: 49478853

Gene position: 4231938-4231087 (Counterclockwise)

Preceding gene: 49481524

Following gene: 49481520

Centisome position: 80.8

GC content: 39.44

Gene sequence:

>852_bases
ATGATTCGAGTAGGATATTTAGGACCAGAAGCAACATTTACAAATATGGCGGTGAGTCGTTTTTTTCCGGAAGCAGAGCA
TGTACCGTATCGAACGATTCCAGATTGTATGGATGCAGCTGCAAATGGAAATGTAGATTATGCAGTGGTACCACTAGAAA
ACGCCATAGAAGGTTCAGTGAATATAACAGTTGATTACCTCGTGCATGAGCAGCCGCTTTCTATTGTAGGAGAAATTACA
GTACCAATTCAGCAACATTTACTTGTACATCCGCAGTATGCAGAAGTGTGGGAAGAAGTATATGCAGTACATTCTCATCC
ACACGCTATTGCCCAATGTCATAAATTTTTAAATGAAGAATTAAAAGGGGTAACTGCCCGAGATATGACATCAACAAGTG
CTGCTGCACAATATGTGAAAGAACATCCTGAAGAAAAAATCGCTGCCATTGCAAATGAAGCAGCTGCAGAGAAATACGGA
TTGACGATTGTAAGACGAAGTATTCATACACATAAAAATAATCATACACGTTTCCTCGTGCTCCATAAGAAAAAGAAAGC
AATACTCCCAAATAACGGAGAAAATCGCGGTGAGAAAACGACGCTTATGATAACGTTACCTGCTGATTATGCAGGGGCAC
TATATCAAGTGTTATCAGCTTTTGCATGGAGGAAATTAAATTTATCAAAAATCGAATCTCGTCCGATGAAAACAGGACTT
GGAAATTACTTTTTCTTAATCGATGTCGATAAAGCATACGATGACGTATTATTGCCAGGCGTAACGATGGAACTTGAAGC
ACTCGGTTTTTCTGTTACGGTGCTGGGGAGTTATTCTTCTTATTGGTTGTAA

Upstream 100 bases:

>100_bases
CTAGCGAATGCTAGTCTTTTTTAAATATTCGAAATTTACATAGAAGAATATAAAAAAGTATGGTATAACAGTAAGAAAAT
GAAAAAGAGGGGAAAAGACG

Downstream 100 bases:

>100_bases
AGAGGAGTATTTGTAATTAAGTTGATATAAATTCAGTCGCTAGTATATAAATAAAATCCCACCTATAAATGGTGGGATTT
TTTATTTTAACTTCGCAAGA

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MIRVGYLGPEATFTNMAVSRFFPEAEHVPYRTIPDCMDAAANGNVDYAVVPLENAIEGSVNITVDYLVHEQPLSIVGEIT
VPIQQHLLVHPQYAEVWEEVYAVHSHPHAIAQCHKFLNEELKGVTARDMTSTSAAAQYVKEHPEEKIAAIANEAAAEKYG
LTIVRRSIHTHKNNHTRFLVLHKKKKAILPNNGENRGEKTTLMITLPADYAGALYQVLSAFAWRKLNLSKIESRPMKTGL
GNYFFLIDVDKAYDDVLLPGVTMELEALGFSVTVLGSYSSYWL

Sequences:

>Translated_283_residues
MIRVGYLGPEATFTNMAVSRFFPEAEHVPYRTIPDCMDAAANGNVDYAVVPLENAIEGSVNITVDYLVHEQPLSIVGEIT
VPIQQHLLVHPQYAEVWEEVYAVHSHPHAIAQCHKFLNEELKGVTARDMTSTSAAAQYVKEHPEEKIAAIANEAAAEKYG
LTIVRRSIHTHKNNHTRFLVLHKKKKAILPNNGENRGEKTTLMITLPADYAGALYQVLSAFAWRKLNLSKIESRPMKTGL
GNYFFLIDVDKAYDDVLLPGVTMELEALGFSVTVLGSYSSYWL
>Mature_283_residues
MIRVGYLGPEATFTNMAVSRFFPEAEHVPYRTIPDCMDAAANGNVDYAVVPLENAIEGSVNITVDYLVHEQPLSIVGEIT
VPIQQHLLVHPQYAEVWEEVYAVHSHPHAIAQCHKFLNEELKGVTARDMTSTSAAAQYVKEHPEEKIAAIANEAAAEKYG
LTIVRRSIHTHKNNHTRFLVLHKKKKAILPNNGENRGEKTTLMITLPADYAGALYQVLSAFAWRKLNLSKIESRPMKTGL
GNYFFLIDVDKAYDDVLLPGVTMELEALGFSVTVLGSYSSYWL

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=282, Percent_Identity=32.2695035460993, Blast_Score=123, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324013, Length=280, Percent_Identity=30.3571428571429, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF00800 PDT [H]

EC number: =4.2.1.51 [H]

Molecular weight: Translated: 31580; Mature: 31580

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVGYLGPEATFTNMAVSRFFPEAEHVPYRTIPDCMDAAANGNVDYAVVPLENAIEGSV
CEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCE
NITVDYLVHEQPLSIVGEITVPIQQHLLVHPQYAEVWEEVYAVHSHPHAIAQCHKFLNEE
EEEEEEEEECCCHHEEEEEEECHHHHEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LKGVTARDMTSTSAAAQYVKEHPEEKIAAIANEAAAEKYGLTIVRRSIHTHKNNHTRFLV
HCCCCHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LHKKKKAILPNNGENRGEKTTLMITLPADYAGALYQVLSAFAWRKLNLSKIESRPMKTGL
EEECCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCC
GNYFFLIDVDKAYDDVLLPGVTMELEALGFSVTVLGSYSSYWL
CCEEEEEECCCCCCCEECCCCEEEEECCCEEEEEEECCCCCCC
>Mature Secondary Structure
MIRVGYLGPEATFTNMAVSRFFPEAEHVPYRTIPDCMDAAANGNVDYAVVPLENAIEGSV
CEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCE
NITVDYLVHEQPLSIVGEITVPIQQHLLVHPQYAEVWEEVYAVHSHPHAIAQCHKFLNEE
EEEEEEEEECCCHHEEEEEEECHHHHEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LKGVTARDMTSTSAAAQYVKEHPEEKIAAIANEAAAEKYGLTIVRRSIHTHKNNHTRFLV
HCCCCHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LHKKKKAILPNNGENRGEKTTLMITLPADYAGALYQVLSAFAWRKLNLSKIESRPMKTGL
EEECCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCC
GNYFFLIDVDKAYDDVLLPGVTMELEALGFSVTVLGSYSSYWL
CCEEEEEECCCCCCCEECCCCEEEEECCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2537815; 9384377; 8444804 [H]