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The map label for this gene is trxB [H]

Identifier: 49475890

GI number: 49475890

Start: 1296518

End: 1297471

Strand: Reverse

Name: trxB [H]

Synonym: BH11660

Alternate gene names: 49475890

Gene position: 1297471-1296518 (Counterclockwise)

Preceding gene: 49475892

Following gene: 49475889

Centisome position: 67.19

GC content: 44.65

Gene sequence:

>954_bases
ATGGTGCAGTCGCATGTTCGTCTGCTTATTATTGGTTCTGGTCCAGCTGGTTATACAGCGGCGATCTATGCAGCGAGAGG
AATGCTCAAACCGGTTTTGATTACTGGATTACAGCAAGGCGGGCAGTTGATGATTACAACTGATGTCGAGAATTATCCAG
GTTTTGCTGATCCAATTCAGGGACCATGGTTGATGGAACAAATGGCAAAACAAGCCGAAAATATGGGCACGAAAATTGTC
TATGATAATATTACAAAGGCTGATTTATCGAAGCGCCCTTTTATCTTATACGGAGATTCAGGAGCGCAATATTGTTGTGA
TGCGCTCATTATTGCAACCGGAGCGCAGGCGCGCTGGCTTGGTTTGGAGAGTGAACAGGTATTTATGGGTGGGGGTGTTT
CTGCTTGCGCTACATGTGATGGTTTCTTTTATCGTGATAAGGACGTTATTGTTGTGGGAGGGGGAAATACAGCCGTTGAA
GAAGCCCTTTATTTATCGCATTTGGCGAAGAGGGTAAGCGTAGTTCATCGGCGGGATTATTTTCGGGCAGAAAAAATTTT
GCAAGATAGGTTATTTGCCCGTGATAATGTGTGTGTTCTTTGGGATCATGTGGTAGAAGAAATTATTGGTTTGCCAGCTC
GTGCTTCAATAGGAGCTGTTGTGACAGGTGTACGTCTTAAAAATGTTAAAACCGGTCAAAAAGTTCATGTGGATACGGAT
GGAATATTTATTGCTATCGGACATGACCCTGCTGTCTCTTTGTTTGAAGGTCAACTAAAACAAAAATCAGGTGGCTACTT
ATGGACAGCGCCGGATTCAACAGCAACAAGCATTGCTGGTGTTTTTGCTGCGGGAGATGTCGTAGACGACGTATTTCGTC
AGGCAATAACAGCAGCGGGGAGGGGATGTATGGCAGCATTGGAGGCAGAACGATTTTTGGAGTTGCAGATATAG

Upstream 100 bases:

>100_bases
GTATACACCATAATTTAGGCTGTTGAAAAATGTTTTTTTTAAGGCTGCATTTCGTTATAATTTATAGAAGAGTTAAGTAA
CAAAAAATGAAAGGGATTTT

Downstream 100 bases:

>100_bases
ACGTCAAAAATAGATATCTATCGGAAAAGTGAAAAAAGTAAGAGGAAAAATTAATTGTGTCGTCACCATTGGATTGGGAT
AAGTTAAGGGTTTTTCATGC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MVQSHVRLLIIGSGPAGYTAAIYAARGMLKPVLITGLQQGGQLMITTDVENYPGFADPIQGPWLMEQMAKQAENMGTKIV
YDNITKADLSKRPFILYGDSGAQYCCDALIIATGAQARWLGLESEQVFMGGGVSACATCDGFFYRDKDVIVVGGGNTAVE
EALYLSHLAKRVSVVHRRDYFRAEKILQDRLFARDNVCVLWDHVVEEIIGLPARASIGAVVTGVRLKNVKTGQKVHVDTD
GIFIAIGHDPAVSLFEGQLKQKSGGYLWTAPDSTATSIAGVFAAGDVVDDVFRQAITAAGRGCMAALEAERFLELQI

Sequences:

>Translated_317_residues
MVQSHVRLLIIGSGPAGYTAAIYAARGMLKPVLITGLQQGGQLMITTDVENYPGFADPIQGPWLMEQMAKQAENMGTKIV
YDNITKADLSKRPFILYGDSGAQYCCDALIIATGAQARWLGLESEQVFMGGGVSACATCDGFFYRDKDVIVVGGGNTAVE
EALYLSHLAKRVSVVHRRDYFRAEKILQDRLFARDNVCVLWDHVVEEIIGLPARASIGAVVTGVRLKNVKTGQKVHVDTD
GIFIAIGHDPAVSLFEGQLKQKSGGYLWTAPDSTATSIAGVFAAGDVVDDVFRQAITAAGRGCMAALEAERFLELQI
>Mature_317_residues
MVQSHVRLLIIGSGPAGYTAAIYAARGMLKPVLITGLQQGGQLMITTDVENYPGFADPIQGPWLMEQMAKQAENMGTKIV
YDNITKADLSKRPFILYGDSGAQYCCDALIIATGAQARWLGLESEQVFMGGGVSACATCDGFFYRDKDVIVVGGGNTAVE
EALYLSHLAKRVSVVHRRDYFRAEKILQDRLFARDNVCVLWDHVVEEIIGLPARASIGAVVTGVRLKNVKTGQKVHVDTD
GIFIAIGHDPAVSLFEGQLKQKSGGYLWTAPDSTATSIAGVFAAGDVVDDVFRQAITAAGRGCMAALEAERFLELQI

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=318, Percent_Identity=55.9748427672956, Blast_Score=350, Evalue=5e-98,
Organism=Escherichia coli, GI87081763, Length=313, Percent_Identity=30.9904153354633, Blast_Score=115, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6321898, Length=322, Percent_Identity=43.167701863354, Blast_Score=276, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6320560, Length=319, Percent_Identity=41.692789968652, Blast_Score=265, Evalue=5e-72,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34162; Mature: 34162

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQSHVRLLIIGSGPAGYTAAIYAARGMLKPVLITGLQQGGQLMITTDVENYPGFADPIQ
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC
GPWLMEQMAKQAENMGTKIVYDNITKADLSKRPFILYGDSGAQYCCDALIIATGAQARWL
CCHHHHHHHHHHHHCCCEEEECCCCHHCCCCCCEEEECCCCHHHHHHHHHEECCCCEEEE
GLESEQVFMGGGVSACATCDGFFYRDKDVIVVGGGNTAVEEALYLSHLAKRVSVVHRRDY
CCCCCEEEECCCCHHHHCCCCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
FRAEKILQDRLFARDNVCVLWDHVVEEIIGLPARASIGAVVTGVRLKNVKTGQKVHVDTD
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCCCHHEECEEEECCCCCCEEEEECC
GIFIAIGHDPAVSLFEGQLKQKSGGYLWTAPDSTATSIAGVFAAGDVVDDVFRQAITAAG
CEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RGCMAALEAERFLELQI
CHHHHHHHHHHEEEECC
>Mature Secondary Structure
MVQSHVRLLIIGSGPAGYTAAIYAARGMLKPVLITGLQQGGQLMITTDVENYPGFADPIQ
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC
GPWLMEQMAKQAENMGTKIVYDNITKADLSKRPFILYGDSGAQYCCDALIIATGAQARWL
CCHHHHHHHHHHHHCCCEEEECCCCHHCCCCCCEEEECCCCHHHHHHHHHEECCCCEEEE
GLESEQVFMGGGVSACATCDGFFYRDKDVIVVGGGNTAVEEALYLSHLAKRVSVVHRRDY
CCCCCEEEECCCCHHHHCCCCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
FRAEKILQDRLFARDNVCVLWDHVVEEIIGLPARASIGAVVTGVRLKNVKTGQKVHVDTD
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCCCHHEECEEEECCCCCCEEEEECC
GIFIAIGHDPAVSLFEGQLKQKSGGYLWTAPDSTATSIAGVFAAGDVVDDVFRQAITAAG
CEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RGCMAALEAERFLELQI
CHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA