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The map label for this gene is murB [H]

Identifier: 49475853

GI number: 49475853

Start: 1237253

End: 1238308

Strand: Reverse

Name: murB [H]

Synonym: BH11220

Alternate gene names: 49475853

Gene position: 1238308-1237253 (Counterclockwise)

Preceding gene: 49475854

Following gene: 49475852

Centisome position: 64.13

GC content: 43.37

Gene sequence:

>1056_bases
ATGTTGTTTTTCTTGGTGCTGGCAATATCACACAATGGGCTTGTGCTTTGCCTAACCAATTGGCGGTATTTGATAACAAT
GATAAATTTTCAGCTGATTGATGGTGAGGCGCTGTTAGCGCGTTTACAACCGACGTTAGGTGGTATAAAGGGAAAACTTA
CGCCTAATATGGATATGCAGAAGGTGACGTGGTTTCGCACTGGTGGTTTGGCTGAACTTTTTTATCAGCCTGCTGATGAG
GTAGATTTAGCTTTTTTTCTGCAAAATTTGCCTGAATCTATTCCTGTAACAATTGTGGGGATTGGTTCTAATCTTCTGGT
ACGAGATGGTGGGATTCCTGGAGTTGTTATTCGTCTTTCGGCCAAAGGTTTTGGGCAAGTCCAGCAGGTTTCTCCAACGG
GCTTTTTGGTTGGTGCTGCTACGGCAGATAAACATTTAGCAGCGGCCGCTTTAGAGGCAGAGATTGCAGGTTTTCATTTT
TATCATGGTATTCCTGGAGGTCTTGGAGGAGCACTCAAAATGAATGCAGGGGCTAATGGTGTTGAGACAGCTGCACGTGT
TGTTGAGGTTTATGCACTTGATCGTAGAGGACAGTGTCATACCTTAAGTTTGGCAGATATGCATTATTCTTATCGTCATT
GTGCTGTTCCTGAAGATTTCATTTTTACGGCTGCTTTATTAGAAGGAAAGCCAGGAAATAAAGGTGATATTCGTGCTGCT
ATGGATGAAGTTGCTCTTCATCGGGAAAGCGTGCAGCCTGTGCGAGAAAAAACAGGAGGCTCAACTTTTCGAAATCCTAA
AGATATTTCTGCGTGGCGTGTTATTGATGAAGCAGGGTGCCGTGGTCTACAGATTGGTGGCGCTCAAATGAGTGAAATGC
ATTGTAATTTTATGATTAATACAGGGCAAGCAACAGCCTATGATCTTGAAGCATTGGGCGAAACAGTGCGTGCCCGTGTT
TTTGCTTATTCTTCCCATCTCTTACAGTGGGAAATACAGCGTATTGGTCAATTTGAACAAGGCCGTATCGTCTCTTCTTT
TGACCCATTTAATTGA

Upstream 100 bases:

>100_bases
GTAGAACATATTCAAATGGCTGGTCATCGTGATGTGCGTTTGATTGATTGTTTGGAAGATGTTGTTTCGATTGTCTCTAC
TTTTTCTAAATCTGGTGATT

Downstream 100 bases:

>100_bases
TTTGTTCAGTGTCATAAAAAATTGAGTCATTTCAAAGAGATAATAAAAAAATCTATTAAGAATCAATAAATTAACAAAGA
AACTCTTGCGTCATGCGTCT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MLFFLVLAISHNGLVLCLTNWRYLITMINFQLIDGEALLARLQPTLGGIKGKLTPNMDMQKVTWFRTGGLAELFYQPADE
VDLAFFLQNLPESIPVTIVGIGSNLLVRDGGIPGVVIRLSAKGFGQVQQVSPTGFLVGAATADKHLAAAALEAEIAGFHF
YHGIPGGLGGALKMNAGANGVETAARVVEVYALDRRGQCHTLSLADMHYSYRHCAVPEDFIFTAALLEGKPGNKGDIRAA
MDEVALHRESVQPVREKTGGSTFRNPKDISAWRVIDEAGCRGLQIGGAQMSEMHCNFMINTGQATAYDLEALGETVRARV
FAYSSHLLQWEIQRIGQFEQGRIVSSFDPFN

Sequences:

>Translated_351_residues
MLFFLVLAISHNGLVLCLTNWRYLITMINFQLIDGEALLARLQPTLGGIKGKLTPNMDMQKVTWFRTGGLAELFYQPADE
VDLAFFLQNLPESIPVTIVGIGSNLLVRDGGIPGVVIRLSAKGFGQVQQVSPTGFLVGAATADKHLAAAALEAEIAGFHF
YHGIPGGLGGALKMNAGANGVETAARVVEVYALDRRGQCHTLSLADMHYSYRHCAVPEDFIFTAALLEGKPGNKGDIRAA
MDEVALHRESVQPVREKTGGSTFRNPKDISAWRVIDEAGCRGLQIGGAQMSEMHCNFMINTGQATAYDLEALGETVRARV
FAYSSHLLQWEIQRIGQFEQGRIVSSFDPFN
>Mature_351_residues
MLFFLVLAISHNGLVLCLTNWRYLITMINFQLIDGEALLARLQPTLGGIKGKLTPNMDMQKVTWFRTGGLAELFYQPADE
VDLAFFLQNLPESIPVTIVGIGSNLLVRDGGIPGVVIRLSAKGFGQVQQVSPTGFLVGAATADKHLAAAALEAEIAGFHF
YHGIPGGLGGALKMNAGANGVETAARVVEVYALDRRGQCHTLSLADMHYSYRHCAVPEDFIFTAALLEGKPGNKGDIRAA
MDEVALHRESVQPVREKTGGSTFRNPKDISAWRVIDEAGCRGLQIGGAQMSEMHCNFMINTGQATAYDLEALGETVRARV
FAYSSHLLQWEIQRIGQFEQGRIVSSFDPFN

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 38182; Mature: 38182

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFFLVLAISHNGLVLCLTNWRYLITMINFQLIDGEALLARLQPTLGGIKGKLTPNMDMQ
CEEEEEEEECCCCEEEEECCCEEEEEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCHH
KVTWFRTGGLAELFYQPADEVDLAFFLQNLPESIPVTIVGIGSNLLVRDGGIPGVVIRLS
EEEEEECCCHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCCEEEEEEE
AKGFGQVQQVSPTGFLVGAATADKHLAAAALEAEIAGFHFYHGIPGGLGGALKMNAGANG
CCCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCCCCCEEEECCCCCH
VETAARVVEVYALDRRGQCHTLSLADMHYSYRHCAVPEDFIFTAALLEGKPGNKGDIRAA
HHHHHHHHHEEEECCCCCEEEEEEHHHCCCCCCCCCCHHHHHEEHHHCCCCCCCCCHHHH
MDEVALHRESVQPVREKTGGSTFRNPKDISAWRVIDEAGCRGLQIGGAQMSEMHCNFMIN
HHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHEEEHHCCCCEEEECCCEECCEEEEEEEE
TGQATAYDLEALGETVRARVFAYSSHLLQWEIQRIGQFEQGRIVSSFDPFN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCC
>Mature Secondary Structure
MLFFLVLAISHNGLVLCLTNWRYLITMINFQLIDGEALLARLQPTLGGIKGKLTPNMDMQ
CEEEEEEEECCCCEEEEECCCEEEEEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCHH
KVTWFRTGGLAELFYQPADEVDLAFFLQNLPESIPVTIVGIGSNLLVRDGGIPGVVIRLS
EEEEEECCCHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCCEEEEEEE
AKGFGQVQQVSPTGFLVGAATADKHLAAAALEAEIAGFHFYHGIPGGLGGALKMNAGANG
CCCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCCCCCEEEECCCCCH
VETAARVVEVYALDRRGQCHTLSLADMHYSYRHCAVPEDFIFTAALLEGKPGNKGDIRAA
HHHHHHHHHEEEECCCCCEEEEEEHHHCCCCCCCCCCHHHHHEEHHHCCCCCCCCCHHHH
MDEVALHRESVQPVREKTGGSTFRNPKDISAWRVIDEAGCRGLQIGGAQMSEMHCNFMIN
HHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHEEEHHCCCCEEEECCCEECCEEEEEEEE
TGQATAYDLEALGETVRARVFAYSSHLLQWEIQRIGQFEQGRIVSSFDPFN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA