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The map label for this gene is 46446889

Identifier: 46446889

GI number: 46446889

Start: 1496370

End: 1497515

Strand: Direct

Name: 46446889

Synonym: pc1255

Alternate gene names: NA

Gene position: 1496370-1497515 (Clockwise)

Preceding gene: 46446879

Following gene: 46446890

Centisome position: 61.98

GC content: 35.43

Gene sequence:

>1146_bases
ATGAAAATTAAAGAATTTAATTGGGGACCGACACTCTTCTTAACGATTTATCAGACTCTTCTTCTCCTTTCTTTACCCTT
TTACTTCTACTTTACTCCCCCTTCTTTAGGAATGATTGGAATATCAATCATTTTACTTTATTTAACCGGTTTAAGTATTA
CAGCAGGTTATCACCGATTTTATTCACATCGAAGCTATCGAACAAATTCTTTTGTGGAAATGCTTCTCTTATTTTTTGGT
TCAATGGCTGGTCAGGGAAGTGCTCTAAGATGGTCATTTGATCATCGCTTGCATCATGCCCACGTCGATACAGATTGTGA
CCCTTATTCTATAAAAAAGGGGTTTTGGTATGCTCATTGCCTATGGATTTTAGAAAAGCCTAAAAAAATTGAAGCTAAAG
TTGTGCCCGATTTAATAAAAAATCGTCTTGTTCAATTTCAACATAAATATGATTTCCTTTGTATGCTCATAAGTAATGGA
ATTGCTTTTTTAGTTGTCGGTTGGTTTTTAGATGATTATATGGGAGCTTTTTTTCTAGCTTGCTGGACACGTTTATTTCT
TCTTCATCACTTTACGTGGTTTATCAATTCACTTGCTCACACCTGGGGTGATCGCCCATTTTGCCAAGAGCAATCAGCGG
TCAACAATTATATTTTGGCCCTATTAACTTTTGGTGAAGGTTATCATAACTATCACCATACTTTCTGTAATGATTACCGA
AATGGAATTCGCTGGTTTCATTTTGACCCCACAAAATGGCTCATTTGGACACTTAGCAAATGTGGTTTGACTAAAGAGCT
GAAACGGATGGATTCTTATACCATCCAAAAAAGAATGGTTCTTGAAAGAAAAAGGTTATTACTAGGTCGCGTTTGCAACT
TATGGTATGTAAAAAAAGATGAACTTGAAAAACTTGTTCGCGAACTAGCTGAAAAATTAGTTGTAGAATTTGCTGAATTT
AACCAATTGCGAGTTAACTACCGGCTTGCTCGAAAAGAAGGGCGAGAACCAGATCAATTAAAGGTTTTTAAACAAAAATT
GTCTATCCTCAAAAAAAATCTTAAAAGCAATTGGCGGTTATGGAAACAACTCTCTCGTCATATTTTAAAACTCAAACCTT
TTGAGTCCTTTCCCTGCCCTATTTAA

Upstream 100 bases:

>100_bases
ATGAACAGAAAACAAAACCTTCTTACTTTGCCATTGACTCGCTTGAAATCCCTAAATCATTTATGATGATTCTTTTCGCG
AAAAATCTTTGGAGAAAAAA

Downstream 100 bases:

>100_bases
TTCAAGAACATAACTATTCTGCCTTGATGGGCCCTTACGTTTCTCTCTCAAATCCTATTCCTTTTAAAATAAACTTCTTT
GTTGCTAGTTTTCTAAACTG

Product: putative eucaryotic stearoyl-CoA 9-desaturase

Products: NA

Alternate protein names: Fatty Acid Desaturase; Delta-9 Acyl-Phospholipid Desaturase; Fatty-Acid Desaturase; Delta-9 Desaturase; Acyl-CoA Desaturase; Delta 9 Acyl-Lipid Fatty Acid Desaturase; Fatty Acid Desaturase Subfamily; Fatty Acid Desaturase Family Proteiin; Fatty Acid Desaturase Family Protein; Stearoyl-CoA Desaturase; Fatty Acid Desaturase Domain Protein; Palmitoyl-Monogalactosyldiacylglycerol Delta-7 Desaturase; Delta-9 Acyl-Lipid Desaturase; Delta 9 Acyl-Lipid Desaturase; Stearoyl/Acyl-CoA Desaturase; Membrane-Bound Fatty Acid Desaturase; Long Chain Acyl-CoA Desaturase; Delta-9 Fatty Acid Desaturase; Fatty-Acid Desaturase Transmenbrane Protein; Delta-9 Fatty Ac Id Desaturase; Fatty Acid-CoA Desaturase; Acyl-Coa Desaturase; Delta-9-Acyl-Lipid Fatty Acid Desaturase; Syn-2 Delta 9 Acyl-Lipid Fatty Acid Desaturase; Eucaryotic Stearoyl-CoA 9-Desaturase; Fatty Acid Desaturase Protein

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKIKEFNWGPTLFLTIYQTLLLLSLPFYFYFTPPSLGMIGISIILLYLTGLSITAGYHRFYSHRSYRTNSFVEMLLLFFG
SMAGQGSALRWSFDHRLHHAHVDTDCDPYSIKKGFWYAHCLWILEKPKKIEAKVVPDLIKNRLVQFQHKYDFLCMLISNG
IAFLVVGWFLDDYMGAFFLACWTRLFLLHHFTWFINSLAHTWGDRPFCQEQSAVNNYILALLTFGEGYHNYHHTFCNDYR
NGIRWFHFDPTKWLIWTLSKCGLTKELKRMDSYTIQKRMVLERKRLLLGRVCNLWYVKKDELEKLVRELAEKLVVEFAEF
NQLRVNYRLARKEGREPDQLKVFKQKLSILKKNLKSNWRLWKQLSRHILKLKPFESFPCPI

Sequences:

>Translated_381_residues
MKIKEFNWGPTLFLTIYQTLLLLSLPFYFYFTPPSLGMIGISIILLYLTGLSITAGYHRFYSHRSYRTNSFVEMLLLFFG
SMAGQGSALRWSFDHRLHHAHVDTDCDPYSIKKGFWYAHCLWILEKPKKIEAKVVPDLIKNRLVQFQHKYDFLCMLISNG
IAFLVVGWFLDDYMGAFFLACWTRLFLLHHFTWFINSLAHTWGDRPFCQEQSAVNNYILALLTFGEGYHNYHHTFCNDYR
NGIRWFHFDPTKWLIWTLSKCGLTKELKRMDSYTIQKRMVLERKRLLLGRVCNLWYVKKDELEKLVRELAEKLVVEFAEF
NQLRVNYRLARKEGREPDQLKVFKQKLSILKKNLKSNWRLWKQLSRHILKLKPFESFPCPI
>Mature_381_residues
MKIKEFNWGPTLFLTIYQTLLLLSLPFYFYFTPPSLGMIGISIILLYLTGLSITAGYHRFYSHRSYRTNSFVEMLLLFFG
SMAGQGSALRWSFDHRLHHAHVDTDCDPYSIKKGFWYAHCLWILEKPKKIEAKVVPDLIKNRLVQFQHKYDFLCMLISNG
IAFLVVGWFLDDYMGAFFLACWTRLFLLHHFTWFINSLAHTWGDRPFCQEQSAVNNYILALLTFGEGYHNYHHTFCNDYR
NGIRWFHFDPTKWLIWTLSKCGLTKELKRMDSYTIQKRMVLERKRLLLGRVCNLWYVKKDELEKLVRELAEKLVVEFAEF
NQLRVNYRLARKEGREPDQLKVFKQKLSILKKNLKSNWRLWKQLSRHILKLKPFESFPCPI

Specific function: Unknown

COG id: COG1398

COG function: function code I; Fatty-acid desaturase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI148596961, Length=241, Percent_Identity=34.8547717842324, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI53759151, Length=245, Percent_Identity=31.0204081632653, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI148596938, Length=108, Percent_Identity=37.962962962963, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17540878, Length=247, Percent_Identity=33.1983805668016, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17561776, Length=246, Percent_Identity=32.520325203252, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17561774, Length=254, Percent_Identity=31.496062992126, Blast_Score=125, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6321383, Length=274, Percent_Identity=38.3211678832117, Blast_Score=205, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24646303, Length=247, Percent_Identity=34.412955465587, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24646299, Length=247, Percent_Identity=34.412955465587, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24646305, Length=247, Percent_Identity=34.412955465587, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24646301, Length=247, Percent_Identity=34.412955465587, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24646297, Length=247, Percent_Identity=34.412955465587, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24646500, Length=246, Percent_Identity=34.1463414634146, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI21358573, Length=251, Percent_Identity=33.0677290836653, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21358571, Length=206, Percent_Identity=33.495145631068, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24646295, Length=245, Percent_Identity=31.4285714285714, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24662393, Length=248, Percent_Identity=30.6451612903226, Blast_Score=122, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 45531; Mature: 45531

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKEFNWGPTLFLTIYQTLLLLSLPFYFYFTPPSLGMIGISIILLYLTGLSITAGYHRF
CCCCCCCCCCHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YSHRSYRTNSFVEMLLLFFGSMAGQGSALRWSFDHRLHHAHVDTDCDPYSIKKGFWYAHC
HHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHCCCCCCCCCCCHHHCCHHHHHH
LWILEKPKKIEAKVVPDLIKNRLVQFQHKYDFLCMLISNGIAFLVVGWFLDDYMGAFFLA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
CWTRLFLLHHFTWFINSLAHTWGDRPFCQEQSAVNNYILALLTFGEGYHNYHHTFCNDYR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
NGIRWFHFDPTKWLIWTLSKCGLTKELKRMDSYTIQKRMVLERKRLLLGRVCNLWYVKKD
CCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHH
ELEKLVRELAEKLVVEFAEFNQLRVNYRLARKEGREPDQLKVFKQKLSILKKNLKSNWRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WKQLSRHILKLKPFESFPCPI
HHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKIKEFNWGPTLFLTIYQTLLLLSLPFYFYFTPPSLGMIGISIILLYLTGLSITAGYHRF
CCCCCCCCCCHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YSHRSYRTNSFVEMLLLFFGSMAGQGSALRWSFDHRLHHAHVDTDCDPYSIKKGFWYAHC
HHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHCCCCCCCCCCCHHHCCHHHHHH
LWILEKPKKIEAKVVPDLIKNRLVQFQHKYDFLCMLISNGIAFLVVGWFLDDYMGAFFLA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
CWTRLFLLHHFTWFINSLAHTWGDRPFCQEQSAVNNYILALLTFGEGYHNYHHTFCNDYR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
NGIRWFHFDPTKWLIWTLSKCGLTKELKRMDSYTIQKRMVLERKRLLLGRVCNLWYVKKD
CCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHH
ELEKLVRELAEKLVVEFAEFNQLRVNYRLARKEGREPDQLKVFKQKLSILKKNLKSNWRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WKQLSRHILKLKPFESFPCPI
HHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA