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The map label for this gene is asd [H]

Identifier: 46446736

GI number: 46446736

Start: 1320902

End: 1321969

Strand: Reverse

Name: asd [H]

Synonym: pc1102

Alternate gene names: 46446736

Gene position: 1321969-1320902 (Counterclockwise)

Preceding gene: 46446737

Following gene: 46446735

Centisome position: 54.75

GC content: 40.92

Gene sequence:

>1068_bases
ATGATGAGCGGAGATTTCTTCTTTCGTAACAAAATTCCTGTTGCGATTTTAGGGGCCACAGGTTGTGTAGGGCAAAAGTT
CGTGCAACTTTTAAGCAAACATCCGTGGTTTGAAATTTTTGCTCTATGTGCTTCTGAAAAATCAGCTGGGAAAACTTATC
AAGAAGCTGTTCATTGGACTTTGCCTACTCCAATTCCAGACGAAGTCAAACAAATGCAGGTGCTTACTTGCGAAACTTCT
TTAGATTGTCAGCTAGTTTTTTCTGCTCTAGACTCATCGATTGCCGGATTTATTGAAACCCGCTTTGCTGAAGCTGGCCA
TCTTGTCATTTCTAATTCTCGCAATCATCGAATGGAAGCGAATGTGCCTCTAGTGATTGGAGAAGTCAACCCAGAGCATC
TAGAGCTAGCCAAATCCCAACCTTTTCAACGAGGCATGATCATTACCAACCCTAATTGCTCCGTTATTGGAATGGTTATG
GCTTTAAAACCTTTGATGCCTTTGGGGATAGACGCTGTTCATGTTGTCACCATGCAAGCAATTTCTGGGGCTGGATATCC
TGGTGTGGCAAGTTTGGATATCAATGATAATATTATTCCTTTTATTAAGGGGGAGGAAGGCAAGCTTGAAAGCGAACCTT
TAAAAATTTTAGGGGATTTACAGGGCACTACTCTCCAGCCTGCTTCGATTAAAATTAGTGCTCAATGTAATCGTGTACCT
ATCATAGATGGGCATGTTGCATGCTTATCTATCAAATTAAATGGCTCTGCATCTCCTGAAACTATCATTCAAGCGTGGCG
TGAATTTTCTGGTGAGCCACAAAAATTTCAGTTGCCTTCAGCTCCCTTACATCCCATTTATTATTTTGATGATCCTTTTT
ATCCTCAACCCAGATTTCATCGACTTTTAGATAAAGAAATGGCTGTTTCTATTGGTCGTTTACGTCCTTGTTCTCTAATG
GATTATAAATTTACTCTGCTTTCTCACAATATGACTCGAGGAGCAGCAGGATCGGCTCTACTCAATGCCGAGCTTCTTGT
TAAAAAAGGCTGGGTTTACTGGTCTTAA

Upstream 100 bases:

>100_bases
CAGAACCTAAAAAATACATGCCGAAATATGCATCTGGAGTTGGTGTGAGATTACTTGTGGAGTTTTTAAAGCAGCTTTCA
ATGGTAAAAAATTAATTTTT

Downstream 100 bases:

>100_bases
ATCATAATCATTTTATTTTCAAATACATATAAATTTCTTTTTTACGTTGCTTTTGTTGGCACACGCTTTGCATTGCTATA
TCCAAGTCCTTGAATTTCTT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MMSGDFFFRNKIPVAILGATGCVGQKFVQLLSKHPWFEIFALCASEKSAGKTYQEAVHWTLPTPIPDEVKQMQVLTCETS
LDCQLVFSALDSSIAGFIETRFAEAGHLVISNSRNHRMEANVPLVIGEVNPEHLELAKSQPFQRGMIITNPNCSVIGMVM
ALKPLMPLGIDAVHVVTMQAISGAGYPGVASLDINDNIIPFIKGEEGKLESEPLKILGDLQGTTLQPASIKISAQCNRVP
IIDGHVACLSIKLNGSASPETIIQAWREFSGEPQKFQLPSAPLHPIYYFDDPFYPQPRFHRLLDKEMAVSIGRLRPCSLM
DYKFTLLSHNMTRGAAGSALLNAELLVKKGWVYWS

Sequences:

>Translated_355_residues
MMSGDFFFRNKIPVAILGATGCVGQKFVQLLSKHPWFEIFALCASEKSAGKTYQEAVHWTLPTPIPDEVKQMQVLTCETS
LDCQLVFSALDSSIAGFIETRFAEAGHLVISNSRNHRMEANVPLVIGEVNPEHLELAKSQPFQRGMIITNPNCSVIGMVM
ALKPLMPLGIDAVHVVTMQAISGAGYPGVASLDINDNIIPFIKGEEGKLESEPLKILGDLQGTTLQPASIKISAQCNRVP
IIDGHVACLSIKLNGSASPETIIQAWREFSGEPQKFQLPSAPLHPIYYFDDPFYPQPRFHRLLDKEMAVSIGRLRPCSLM
DYKFTLLSHNMTRGAAGSALLNAELLVKKGWVYWS
>Mature_355_residues
MMSGDFFFRNKIPVAILGATGCVGQKFVQLLSKHPWFEIFALCASEKSAGKTYQEAVHWTLPTPIPDEVKQMQVLTCETS
LDCQLVFSALDSSIAGFIETRFAEAGHLVISNSRNHRMEANVPLVIGEVNPEHLELAKSQPFQRGMIITNPNCSVIGMVM
ALKPLMPLGIDAVHVVTMQAISGAGYPGVASLDINDNIIPFIKGEEGKLESEPLKILGDLQGTTLQPASIKISAQCNRVP
IIDGHVACLSIKLNGSASPETIIQAWREFSGEPQKFQLPSAPLHPIYYFDDPFYPQPRFHRLLDKEMAVSIGRLRPCSLM
DYKFTLLSHNMTRGAAGSALLNAELLVKKGWVYWS

Specific function: This enzyme catalyzes the second step in the common metabolic pathway to synthesize Thr and Met from Asp [H]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320362, Length=358, Percent_Identity=44.1340782122905, Blast_Score=279, Evalue=5e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR005676
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 39079; Mature: 39079

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSGDFFFRNKIPVAILGATGCVGQKFVQLLSKHPWFEIFALCASEKSAGKTYQEAVHWT
CCCCCEEEECCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHEEEE
LPTPIPDEVKQMQVLTCETSLDCQLVFSALDSSIAGFIETRFAEAGHLVISNSRNHRMEA
CCCCCCHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEC
NVPLVIGEVNPEHLELAKSQPFQRGMIITNPNCSVIGMVMALKPLMPLGIDAVHVVTMQA
CCCEEEECCCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHH
ISGAGYPGVASLDINDNIIPFIKGEEGKLESEPLKILGDLQGTTLQPASIKISAQCNRVP
HCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHEECCCCCEECCCEEEEEECCCCCE
IIDGHVACLSIKLNGSASPETIIQAWREFSGEPQKFQLPSAPLHPIYYFDDPFYPQPRFH
EECCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCCCCEEEEECCCCCCCHHHH
RLLDKEMAVSIGRLRPCSLMDYKFTLLSHNMTRGAAGSALLNAELLVKKGWVYWS
HHHHHHHHHHHCCCCCCEEECEEEEEEECCCCCCCCCCHHEEHEEEEECCCEEEC
>Mature Secondary Structure
MMSGDFFFRNKIPVAILGATGCVGQKFVQLLSKHPWFEIFALCASEKSAGKTYQEAVHWT
CCCCCEEEECCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHEEEE
LPTPIPDEVKQMQVLTCETSLDCQLVFSALDSSIAGFIETRFAEAGHLVISNSRNHRMEA
CCCCCCHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEC
NVPLVIGEVNPEHLELAKSQPFQRGMIITNPNCSVIGMVMALKPLMPLGIDAVHVVTMQA
CCCEEEECCCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHH
ISGAGYPGVASLDINDNIIPFIKGEEGKLESEPLKILGDLQGTTLQPASIKISAQCNRVP
HCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHEECCCCCEECCCEEEEEECCCCCE
IIDGHVACLSIKLNGSASPETIIQAWREFSGEPQKFQLPSAPLHPIYYFDDPFYPQPRFH
EECCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCCCCEEEEECCCCCCCHHHH
RLLDKEMAVSIGRLRPCSLMDYKFTLLSHNMTRGAAGSALLNAELLVKKGWVYWS
HHHHHHHHHHHCCCCCCEEECEEEEEEECCCCCCCCCCHHEEHEEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]