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The map label for this gene is umuC [H]

Identifier: 46446609

GI number: 46446609

Start: 1173751

End: 1174932

Strand: Reverse

Name: umuC [H]

Synonym: pc0975

Alternate gene names: 46446609

Gene position: 1174932-1173751 (Counterclockwise)

Preceding gene: 46446610

Following gene: 46446608

Centisome position: 48.66

GC content: 36.8

Gene sequence:

>1182_bases
GTGGTTGTTTTATCCAATAATGATGGATGCGTAATTTCCCGTTCTCAAGAAGCCAAGCTTTTGGGCGTTAAAATGGGGGA
ACCTTACTTTCAAATTAAAGCGCTTTGTGAATTTAGAAATATTCAAGTGTTTTCTTCAAATTACGCGCTCTACGGAGATA
TTTCAGAGCGTATCATGAACCTCTTATTCGAACATGCCCCCGACCTAGACATTTATTCAATTGATGAAGCTTTTTTAAAA
TATCCTTCTAGTGTTGCCCCTTCTGATTTAGTTTCTCTTTGTCACGAATTACAAAAGAAGGTTAAAAAATGGGTGGGAAT
GCCTATTTCTTTAGGCCTTGCTAACACAAAGACACTTGCAAAAATGGCCAATGATCTCGCCAAAAAAATTCAAAATTTCT
ATGTGTTTGATTTAAATTCATCGGTTCGTCAAAAGGTCTTACAAAATTATTTGATTGGGGATGTTTGGGGGATTGGACGA
AATTTAAAAGAAAAATTAAATGGAATGAATATTCACACGGCCTGGGAATATGCACAAATGGATCCTTCCATTATTCGCAA
ACGACTGGGTGTGATTGGAGAGCGAATACTATGGGAATTAAGAGGAGTTAGCTGCTTAGAATCAGATGAAAAAGTCTCTA
AAAAAAGTTTGCTTTATTCTAGGTCTTTCGGACATGTTCTTTCAGAGATAACCCCTTTGTCCGAGGCTTTATCTACCTAC
GTTTATACAGTGGCTGAAAAGTTAAGAGCACAGGGAAGCCTAGCAAAAGCGTTGTATATATTTTTAGAATATCAAATTCA
GCCCGGAAAGAAGATGCGCTGTTATGATAGTATTACTGAAATATTTCCAGCTCCAACTAAAGACACAGGAGAGATGATTA
AGGCCGCGAAACGAGGGTTAAATAAAATTTTCCGTCGTGAAGAAAGATATAAGAAATGTGGGGTCATTTTATTAGATCTT
TTACCTGAATCATCTTCAAATTCTGATTTGTTTTTAAATCCTGTAGATCCCAAGCGAACACAATTAATGAATACCATGGA
TGCATTAAATGCTCGTTTTGGTAAAAAAAAATTATTCTTTGGAGCAATGGGAACAGACGTAAGCTGGAAGTCTCGAAAAG
ACTGCAGCTCAAAGCACAATCCTTCTAATTGGCAGCAGCTACCCATTGTTTTAGCTAAGTAA

Upstream 100 bases:

>100_bases
CGTGGAATCATTATCAAGGGATCAATTCATTTTAGTAGATTGCAATAATTTTTATGTATCCTGTGAAAGATTATTCAATC
CTAACCTTGAAAAGAAACCA

Downstream 100 bases:

>100_bases
TATTTGAGGCCATTTTTTTTCTAGATTGCAGTTAACAATAAGTACTGTTAAACTTTGACCTCCTTATGATTTTATGAAGA
GAGGTTTATGTTAGAACAAA

Product: putative SOS mutagenesis and repair protein UmuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MVVLSNNDGCVISRSQEAKLLGVKMGEPYFQIKALCEFRNIQVFSSNYALYGDISERIMNLLFEHAPDLDIYSIDEAFLK
YPSSVAPSDLVSLCHELQKKVKKWVGMPISLGLANTKTLAKMANDLAKKIQNFYVFDLNSSVRQKVLQNYLIGDVWGIGR
NLKEKLNGMNIHTAWEYAQMDPSIIRKRLGVIGERILWELRGVSCLESDEKVSKKSLLYSRSFGHVLSEITPLSEALSTY
VYTVAEKLRAQGSLAKALYIFLEYQIQPGKKMRCYDSITEIFPAPTKDTGEMIKAAKRGLNKIFRREERYKKCGVILLDL
LPESSSNSDLFLNPVDPKRTQLMNTMDALNARFGKKKLFFGAMGTDVSWKSRKDCSSKHNPSNWQQLPIVLAK

Sequences:

>Translated_393_residues
MVVLSNNDGCVISRSQEAKLLGVKMGEPYFQIKALCEFRNIQVFSSNYALYGDISERIMNLLFEHAPDLDIYSIDEAFLK
YPSSVAPSDLVSLCHELQKKVKKWVGMPISLGLANTKTLAKMANDLAKKIQNFYVFDLNSSVRQKVLQNYLIGDVWGIGR
NLKEKLNGMNIHTAWEYAQMDPSIIRKRLGVIGERILWELRGVSCLESDEKVSKKSLLYSRSFGHVLSEITPLSEALSTY
VYTVAEKLRAQGSLAKALYIFLEYQIQPGKKMRCYDSITEIFPAPTKDTGEMIKAAKRGLNKIFRREERYKKCGVILLDL
LPESSSNSDLFLNPVDPKRTQLMNTMDALNARFGKKKLFFGAMGTDVSWKSRKDCSSKHNPSNWQQLPIVLAK
>Mature_393_residues
MVVLSNNDGCVISRSQEAKLLGVKMGEPYFQIKALCEFRNIQVFSSNYALYGDISERIMNLLFEHAPDLDIYSIDEAFLK
YPSSVAPSDLVSLCHELQKKVKKWVGMPISLGLANTKTLAKMANDLAKKIQNFYVFDLNSSVRQKVLQNYLIGDVWGIGR
NLKEKLNGMNIHTAWEYAQMDPSIIRKRLGVIGERILWELRGVSCLESDEKVSKKSLLYSRSFGHVLSEITPLSEALSTY
VYTVAEKLRAQGSLAKALYIFLEYQIQPGKKMRCYDSITEIFPAPTKDTGEMIKAAKRGLNKIFRREERYKKCGVILLDL
LPESSSNSDLFLNPVDPKRTQLMNTMDALNARFGKKKLFFGAMGTDVSWKSRKDCSSKHNPSNWQQLPIVLAK

Specific function: Involved in UV protection and mutation [H]

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=378, Percent_Identity=38.8888888888889, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI1786425, Length=234, Percent_Identity=24.3589743589744, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: NA

Molecular weight: Translated: 44579; Mature: 44579

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVLSNNDGCVISRSQEAKLLGVKMGEPYFQIKALCEFRNIQVFSSNYALYGDISERIMN
CEEEECCCCEEEECCCCCEEEEEECCCCHHHHHHHHHHHCEEEEECCEEEEECHHHHHHH
LLFEHAPDLDIYSIDEAFLKYPSSVAPSDLVSLCHELQKKVKKWVGMPISLGLANTKTLA
HHHHCCCCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHH
KMANDLAKKIQNFYVFDLNSSVRQKVLQNYLIGDVWGIGRNLKEKLNGMNIHTAWEYAQM
HHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEHHHHHHC
DPSIIRKRLGVIGERILWELRGVSCLESDEKVSKKSLLYSRSFGHVLSEITPLSEALSTY
CHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYTVAEKLRAQGSLAKALYIFLEYQIQPGKKMRCYDSITEIFPAPTKDTGEMIKAAKRGL
HHHHHHHHHHCCHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHH
NKIFRREERYKKCGVILLDLLPESSSNSDLFLNPVDPKRTQLMNTMDALNARFGKKKLFF
HHHHHHHHHHHHHCEEEEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCEEEE
GAMGTDVSWKSRKDCSSKHNPSNWQQLPIVLAK
EECCCCCCCCCCCCCCCCCCCCCCCCCCEEECC
>Mature Secondary Structure
MVVLSNNDGCVISRSQEAKLLGVKMGEPYFQIKALCEFRNIQVFSSNYALYGDISERIMN
CEEEECCCCEEEECCCCCEEEEEECCCCHHHHHHHHHHHCEEEEECCEEEEECHHHHHHH
LLFEHAPDLDIYSIDEAFLKYPSSVAPSDLVSLCHELQKKVKKWVGMPISLGLANTKTLA
HHHHCCCCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHH
KMANDLAKKIQNFYVFDLNSSVRQKVLQNYLIGDVWGIGRNLKEKLNGMNIHTAWEYAQM
HHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEHHHHHHC
DPSIIRKRLGVIGERILWELRGVSCLESDEKVSKKSLLYSRSFGHVLSEITPLSEALSTY
CHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYTVAEKLRAQGSLAKALYIFLEYQIQPGKKMRCYDSITEIFPAPTKDTGEMIKAAKRGL
HHHHHHHHHHCCHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHH
NKIFRREERYKKCGVILLDLLPESSSNSDLFLNPVDPKRTQLMNTMDALNARFGKKKLFF
HHHHHHHHHHHHHCEEEEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCEEEE
GAMGTDVSWKSRKDCSSKHNPSNWQQLPIVLAK
EECCCCCCCCCCCCCCCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2129552 [H]