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The map label for this gene is aroC

Identifier: 46446518

GI number: 46446518

Start: 1068425

End: 1069528

Strand: Direct

Name: aroC

Synonym: pc0884

Alternate gene names: 46446518

Gene position: 1068425-1069528 (Clockwise)

Preceding gene: 46446517

Following gene: 46446519

Centisome position: 44.25

GC content: 40.4

Gene sequence:

>1104_bases
ATGGCATCTAACAGTTTTGGTCATTTATTTAAAATGACGACTTGGGGGGAATCTCATGGAAAAGCGATGGGCGTTGTGAT
TGATGGCTGTCCCTCTGGAATTTTTCTAACTGAGCAGGACATCAATCAAGAGCTATATTGGAGGAAACCTGGCCGCAATG
AACTAACTTCACCAAGGCTAGAAGAAGATCAAGTAGAAATCTTATCGGGTTTATTTAATGGACAAACAACTGGAGCCCCT
ATCTCTTTGATCATTTGGAATAAAGATGTAAATTCCAGCGCTTATGAAGGAATGCATACCCTTTTTCGTCCAGGCCATGC
AAATTATACCTATTCAAATAAATACGGGATTTTTGATTATCGAGGAGGTGGCCGAGCGTCAGCAAGAGAGACTGTTTGCC
GTGTCGCTGCTGGAGCCATTGCAAAGAAAATATTATCAGACGTTGGAATTTCAGTGGTTGCTTATCTCTATTCCATAGGA
GAAATAGAGGGAAAAATTGAATTATCAGACCATGTAAATAACGTGCCTTTATTGCAACAAACCATTCGCAATAGTTCCCT
TTTTTCTCCCTCACCAGCTGCTGAAAAAATGAAAGGCGTTTTAGAAGAAGCCAGAAAAGAGGGGGATTCTGTGGGAGGGA
TTGTTGAAGCAATGGCTTTTAATGTTCCTTGTGGATGGGGTGACCCTGTTTACGAAAAATTAGAGGCAAATTTGGCAAAA
GCTATGCTGTCTATTCCAGCTTCTAAAGGATTTGAGATAGGAGAGGGATTCAAGGCTTCTCAGATGAGAGGAACTGAACA
TAATGATTTATTTGGAATCCAAAATGATCAAATTTCTTTTGTAACTAACCATGCTGGAGGAACTTTGGGGGGAATTTCAA
CAGGGGAGCCTATTATCATTAAAGTCCCTTTTAAGCCAACTTCAAGCATAAATAAGGTGCAGACTTCTTTGAATGAGAAA
GGTGAAATTTGTGATTATCGTTTACCCACTGGATCTCGTCACGATCCTTGCGTTGCCATTCGCGCTGTTCCTGTTGTTGA
GGCTATGATGGCATTAGTATTAGTTGATGCTTTTTTGATGAGCAAATTTTGTCAGCTGAATTGA

Upstream 100 bases:

>100_bases
GAAAATTGGGCAGACCAAACTATCGATATGAACGGATCTATGAACAACGATTTTTCTGTTCATCTACTCATGAGCCTTCA
ATTTGTTAAAGAGGAAAATA

Downstream 100 bases:

>100_bases
AATTTTGAGCAATAGATGTTCTTTATTTTATCTATTTTTAATTAAATAGATAGATATTTTAAAACTTTTATTGTAAAAAC
TTATAAAGTTAAATCAATTT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MASNSFGHLFKMTTWGESHGKAMGVVIDGCPSGIFLTEQDINQELYWRKPGRNELTSPRLEEDQVEILSGLFNGQTTGAP
ISLIIWNKDVNSSAYEGMHTLFRPGHANYTYSNKYGIFDYRGGGRASARETVCRVAAGAIAKKILSDVGISVVAYLYSIG
EIEGKIELSDHVNNVPLLQQTIRNSSLFSPSPAAEKMKGVLEEARKEGDSVGGIVEAMAFNVPCGWGDPVYEKLEANLAK
AMLSIPASKGFEIGEGFKASQMRGTEHNDLFGIQNDQISFVTNHAGGTLGGISTGEPIIIKVPFKPTSSINKVQTSLNEK
GEICDYRLPTGSRHDPCVAIRAVPVVEAMMALVLVDAFLMSKFCQLN

Sequences:

>Translated_367_residues
MASNSFGHLFKMTTWGESHGKAMGVVIDGCPSGIFLTEQDINQELYWRKPGRNELTSPRLEEDQVEILSGLFNGQTTGAP
ISLIIWNKDVNSSAYEGMHTLFRPGHANYTYSNKYGIFDYRGGGRASARETVCRVAAGAIAKKILSDVGISVVAYLYSIG
EIEGKIELSDHVNNVPLLQQTIRNSSLFSPSPAAEKMKGVLEEARKEGDSVGGIVEAMAFNVPCGWGDPVYEKLEANLAK
AMLSIPASKGFEIGEGFKASQMRGTEHNDLFGIQNDQISFVTNHAGGTLGGISTGEPIIIKVPFKPTSSINKVQTSLNEK
GEICDYRLPTGSRHDPCVAIRAVPVVEAMMALVLVDAFLMSKFCQLN
>Mature_366_residues
ASNSFGHLFKMTTWGESHGKAMGVVIDGCPSGIFLTEQDINQELYWRKPGRNELTSPRLEEDQVEILSGLFNGQTTGAPI
SLIIWNKDVNSSAYEGMHTLFRPGHANYTYSNKYGIFDYRGGGRASARETVCRVAAGAIAKKILSDVGISVVAYLYSIGE
IEGKIELSDHVNNVPLLQQTIRNSSLFSPSPAAEKMKGVLEEARKEGDSVGGIVEAMAFNVPCGWGDPVYEKLEANLAKA
MLSIPASKGFEIGEGFKASQMRGTEHNDLFGIQNDQISFVTNHAGGTLGGISTGEPIIIKVPFKPTSSINKVQTSLNEKG
EICDYRLPTGSRHDPCVAIRAVPVVEAMMALVLVDAFLMSKFCQLN

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=364, Percent_Identity=47.2527472527472, Blast_Score=302, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=45.2316076294278, Blast_Score=304, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_PARUW (Q6MCU1)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007883.1
- ProteinModelPortal:   Q6MCU1
- SMR:   Q6MCU1
- STRING:   Q6MCU1
- GeneID:   2779773
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0884
- NMPDR:   fig|264201.1.peg.884
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   TATIGKE
- PhylomeDB:   Q6MCU1
- ProtClustDB:   PRK05382
- BioCyc:   CPRO264201:PC0884-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39787; Mature: 39656

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASNSFGHLFKMTTWGESHGKAMGVVIDGCPSGIFLTEQDINQELYWRKPGRNELTSPRL
CCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEHHHCCCCEEECCCCCCCCCCCCC
EEDQVEILSGLFNGQTTGAPISLIIWNKDVNSSAYEGMHTLFRPGHANYTYSNKYGIFDY
CHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEECCCCCEEEE
RGGGRASARETVCRVAAGAIAKKILSDVGISVVAYLYSIGEIEGKIELSDHVNNVPLLQQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHH
TIRNSSLFSPSPAAEKMKGVLEEARKEGDSVGGIVEAMAFNVPCGWGDPVYEKLEANLAK
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
AMLSIPASKGFEIGEGFKASQMRGTEHNDLFGIQNDQISFVTNHAGGTLGGISTGEPIII
HHHHCCCCCCCCCCCCCCHHHCCCCCCCCEECCCCCCEEEEEECCCCCCCCCCCCCCEEE
KVPFKPTSSINKVQTSLNEKGEICDYRLPTGSRHDPCVAIRAVPVVEAMMALVLVDAFLM
EECCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
SKFCQLN
HHHHCCC
>Mature Secondary Structure 
ASNSFGHLFKMTTWGESHGKAMGVVIDGCPSGIFLTEQDINQELYWRKPGRNELTSPRL
CCCCCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEHHHCCCCEEECCCCCCCCCCCCC
EEDQVEILSGLFNGQTTGAPISLIIWNKDVNSSAYEGMHTLFRPGHANYTYSNKYGIFDY
CHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEECCCCCEEEE
RGGGRASARETVCRVAAGAIAKKILSDVGISVVAYLYSIGEIEGKIELSDHVNNVPLLQQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHH
TIRNSSLFSPSPAAEKMKGVLEEARKEGDSVGGIVEAMAFNVPCGWGDPVYEKLEANLAK
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
AMLSIPASKGFEIGEGFKASQMRGTEHNDLFGIQNDQISFVTNHAGGTLGGISTGEPIII
HHHHCCCCCCCCCCCCCCHHHCCCCCCCCEECCCCCCEEEEEECCCCCCCCCCCCCCEEE
KVPFKPTSSINKVQTSLNEKGEICDYRLPTGSRHDPCVAIRAVPVVEAMMALVLVDAFLM
EECCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
SKFCQLN
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA