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The map label for this gene is aroL [H]

Identifier: 46446517

GI number: 46446517

Start: 1067824

End: 1068435

Strand: Direct

Name: aroL [H]

Synonym: pc0883

Alternate gene names: 46446517

Gene position: 1067824-1068435 (Clockwise)

Preceding gene: 46446516

Following gene: 46446518

Centisome position: 44.23

GC content: 34.8

Gene sequence:

>612_bases
TTGCATCAAAAAGAGTTTTCCCAACTTTATTCAAGATTTAAAAAAACTTGGGGCTCGGTTTACATGATTTCTAAAAGAAG
CGTTGCTTTGATTGGTCTACCTTTGTGTGGGAAAACAACATGGGGGCAATGGCTGGCTAAAAAATTTGAGTATGCCTTTA
TTGATACAGACTGGCTAATTCAACAAAAACATCCTACGTTAACATGTCGAGAAATTTTTCAATTATTTGGGCAGTCCTAT
TTCCGTTCTTTAGAAAGGGATGTCATTGATGACTTAAAGCCAACTAAACAGGTGATTATTGCAACCGGAGGTGGGGTGAT
TTATAATGATCAAAATCGAAATGCGCTAAAAAAATATTGTCGGTTAATTTATTTGAAACTTTCTTTTTCAAACTGGAAAG
AGCGTATTTTCAGTCAAACTGAGTTACCAGCCTATATTTCTCAAGAACAATCTTCGGATGTATCTTTGAAAAAACTCTAT
GCAAGCAGAACGTTAATTTATGAAAATTGGGCAGACCAAACTATCGATATGAACGGATCTATGAACAACGATTTTTCTGT
TCATCTACTCATGAGCCTTCAATTTGTTAAAGAGGAAAATAATGGCATCTAA

Upstream 100 bases:

>100_bases
GAGGGGCTATTGTTGAGAGTTATGATGATCATCGTCTAGCAATGGCTTTAATCGTAGCTGGGCTGGCTAGCGAGGGCATT
ACTGAAGTGAAAGGGATTGA

Downstream 100 bases:

>100_bases
CAGTTTTGGTCATTTATTTAAAATGACGACTTGGGGGGAATCTCATGGAAAAGCGATGGGCGTTGTGATTGATGGCTGTC
CCTCTGGAATTTTTCTAACT

Product: putative shikimate kinase precursor

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MHQKEFSQLYSRFKKTWGSVYMISKRSVALIGLPLCGKTTWGQWLAKKFEYAFIDTDWLIQQKHPTLTCREIFQLFGQSY
FRSLERDVIDDLKPTKQVIIATGGGVIYNDQNRNALKKYCRLIYLKLSFSNWKERIFSQTELPAYISQEQSSDVSLKKLY
ASRTLIYENWADQTIDMNGSMNNDFSVHLLMSLQFVKEENNGI

Sequences:

>Translated_203_residues
MHQKEFSQLYSRFKKTWGSVYMISKRSVALIGLPLCGKTTWGQWLAKKFEYAFIDTDWLIQQKHPTLTCREIFQLFGQSY
FRSLERDVIDDLKPTKQVIIATGGGVIYNDQNRNALKKYCRLIYLKLSFSNWKERIFSQTELPAYISQEQSSDVSLKKLY
ASRTLIYENWADQTIDMNGSMNNDFSVHLLMSLQFVKEENNGI
>Mature_203_residues
MHQKEFSQLYSRFKKTWGSVYMISKRSVALIGLPLCGKTTWGQWLAKKFEYAFIDTDWLIQQKHPTLTCREIFQLFGQSY
FRSLERDVIDDLKPTKQVIIATGGGVIYNDQNRNALKKYCRLIYLKLSFSNWKERIFSQTELPAYISQEQSSDVSLKKLY
ASRTLIYENWADQTIDMNGSMNNDFSVHLLMSLQFVKEENNGI

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=174, Percent_Identity=29.3103448275862, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 23799; Mature: 23799

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQKEFSQLYSRFKKTWGSVYMISKRSVALIGLPLCGKTTWGQWLAKKFEYAFIDTDWLI
CCHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHCEEEECCHHEE
QQKHPTLTCREIFQLFGQSYFRSLERDVIDDLKPTKQVIIATGGGVIYNDQNRNALKKYC
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCCHHHHHHH
RLIYLKLSFSNWKERIFSQTELPAYISQEQSSDVSLKKLYASRTLIYENWADQTIDMNGS
HHEEEEECHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHEEECCCCCEEECCCC
MNNDFSVHLLMSLQFVKEENNGI
CCCCCEEEHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHQKEFSQLYSRFKKTWGSVYMISKRSVALIGLPLCGKTTWGQWLAKKFEYAFIDTDWLI
CCHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHCEEEECCHHEE
QQKHPTLTCREIFQLFGQSYFRSLERDVIDDLKPTKQVIIATGGGVIYNDQNRNALKKYC
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCCHHHHHHH
RLIYLKLSFSNWKERIFSQTELPAYISQEQSSDVSLKKLYASRTLIYENWADQTIDMNGS
HHEEEEECHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHEEECCCCCEEECCCC
MNNDFSVHLLMSLQFVKEENNGI
CCCCCEEEHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA