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The map label for this gene is ttcA [H]

Identifier: 46446494

GI number: 46446494

Start: 1040634

End: 1041374

Strand: Direct

Name: ttcA [H]

Synonym: pc0860

Alternate gene names: 46446494

Gene position: 1040634-1041374 (Clockwise)

Preceding gene: 46446492

Following gene: 46446495

Centisome position: 43.1

GC content: 36.84

Gene sequence:

>741_bases
ATGACTGTTCCAATTGCTCAATCCCCTTGGACCTCTTTAGGAAAAAAATTAGAAAGTACTTTTCGAAAGGCTTTATTTGA
CTATGAGATGCTCAAAGATGTTTCTAAAATAGCTGTCGCATTAAGTGGGGGAAAAGACAGTTTAACACTTCTTTATTTAT
TAAAAGCTATTTCTGGAAGAGGATTTCCAAATTTAGAAATTCATGCAATTCACGTATCTGGAGAATTTTCATGTGGGGCT
GGAGTCAATGAAGATTATTTACGAGCAATATGTCAAGAAATCGGAGTTCAATTAACGACCCGAATTTCAACTCAAAAATT
AGAAAAATTGGAATGCTACAGTTGTTCGAGAGAACGGCGACGGCTTTTATTTGAAGCTGCCAAAAGTTTGGGGATTACGA
CGATTGCTTTTGGTCATCATCGTGATGACCATACACAGACTGTTCTGATGAATTTATTGCATAAAGCTGAATTTGCTGGT
AATCTTCCAAAAATTCACATGCAAGAATATGGTGTGACAATTATTCGACCGTTGATTTACATAGCAGAGAAAAATATTCG
AACTTTTGCACAACAGCAAGGTTTTGCAAGAATTATGTGTCGTTGTCCCGTCGGGCAAAATTCGATGCGTAAACAAGTAG
ACCAATTATTAATCGAAATCGAAACTCTTTTTCCTCATGCTCGTGAAAATATTGCTAAAGCTGGTCTAATTTACGGTTCT
CAAAAAGCCGCGACACCTTGA

Upstream 100 bases:

>100_bases
TCACATTTTTTTATTAAATCATGATTGTAAACTTTACGTTATCTAATAAACTAAGTATAATTTAATCATATTTTTTAAAA
CAATTACAAAAATGACTATT

Downstream 100 bases:

>100_bases
GAATTACAAGATCAAATTTTTTATCATTTACCTAATTAATTATAGGATTAAAAATGGCATATTCTCTTCCAAGCGAGCAT
GAAAGCAGCGTACAAATTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTVPIAQSPWTSLGKKLESTFRKALFDYEMLKDVSKIAVALSGGKDSLTLLYLLKAISGRGFPNLEIHAIHVSGEFSCGA
GVNEDYLRAICQEIGVQLTTRISTQKLEKLECYSCSRERRRLLFEAAKSLGITTIAFGHHRDDHTQTVLMNLLHKAEFAG
NLPKIHMQEYGVTIIRPLIYIAEKNIRTFAQQQGFARIMCRCPVGQNSMRKQVDQLLIEIETLFPHARENIAKAGLIYGS
QKAATP

Sequences:

>Translated_246_residues
MTVPIAQSPWTSLGKKLESTFRKALFDYEMLKDVSKIAVALSGGKDSLTLLYLLKAISGRGFPNLEIHAIHVSGEFSCGA
GVNEDYLRAICQEIGVQLTTRISTQKLEKLECYSCSRERRRLLFEAAKSLGITTIAFGHHRDDHTQTVLMNLLHKAEFAG
NLPKIHMQEYGVTIIRPLIYIAEKNIRTFAQQQGFARIMCRCPVGQNSMRKQVDQLLIEIETLFPHARENIAKAGLIYGS
QKAATP
>Mature_245_residues
TVPIAQSPWTSLGKKLESTFRKALFDYEMLKDVSKIAVALSGGKDSLTLLYLLKAISGRGFPNLEIHAIHVSGEFSCGAG
VNEDYLRAICQEIGVQLTTRISTQKLEKLECYSCSRERRRLLFEAAKSLGITTIAFGHHRDDHTQTVLMNLLHKAEFAGN
LPKIHMQEYGVTIIRPLIYIAEKNIRTFAQQQGFARIMCRCPVGQNSMRKQVDQLLIEIETLFPHARENIAKAGLIYGSQ
KAATP

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=233, Percent_Identity=31.7596566523605, Blast_Score=113, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI193211090, Length=211, Percent_Identity=28.436018957346, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17540090, Length=249, Percent_Identity=24.0963855421687, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24651972, Length=223, Percent_Identity=27.8026905829596, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 27536; Mature: 27405

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPIAQSPWTSLGKKLESTFRKALFDYEMLKDVSKIAVALSGGKDSLTLLYLLKAISGR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
GFPNLEIHAIHVSGEFSCGAGVNEDYLRAICQEIGVQLTTRISTQKLEKLECYSCSRERR
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RLLFEAAKSLGITTIAFGHHRDDHTQTVLMNLLHKAEFAGNLPKIHMQEYGVTIIRPLIY
HHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHH
IAEKNIRTFAQQQGFARIMCRCPVGQNSMRKQVDQLLIEIETLFPHARENIAKAGLIYGS
HHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
QKAATP
CCCCCC
>Mature Secondary Structure 
TVPIAQSPWTSLGKKLESTFRKALFDYEMLKDVSKIAVALSGGKDSLTLLYLLKAISGR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
GFPNLEIHAIHVSGEFSCGAGVNEDYLRAICQEIGVQLTTRISTQKLEKLECYSCSRERR
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RLLFEAAKSLGITTIAFGHHRDDHTQTVLMNLLHKAEFAGNLPKIHMQEYGVTIIRPLIY
HHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHH
IAEKNIRTFAQQQGFARIMCRCPVGQNSMRKQVDQLLIEIETLFPHARENIAKAGLIYGS
HHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
QKAATP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA