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The map label for this gene is rnhB

Identifier: 46446313

GI number: 46446313

Start: 827796

End: 828701

Strand: Reverse

Name: rnhB

Synonym: pc0679

Alternate gene names: 46446313

Gene position: 828701-827796 (Counterclockwise)

Preceding gene: 46446316

Following gene: 46446312

Centisome position: 34.32

GC content: 36.2

Gene sequence:

>906_bases
ATGAGCAGTTTGCCTCCTTTCGTTACAACACTTGACTTAAAATTAGCAGAAAAATTGCTGAAAGATCTCCAACAACAAGG
TTTTTCCATCACTATACCTGCCTATACTCGCTTTTCTGCCAGTAAAAAAGGATTAACATGTACTCTTTATACATCAGGGA
AGTTAGTCGTCCAGGGCAAAGAGCAAGCTCATTTTATTGAGTTTTATCTTGAACCAGAAATTTTAGAGTCCTTTGGATTT
AGCCATCCCACAACTAAAATAGATTTAACCCCACATATTGGAATTGATGAATCTGGAAAAGGAGATTTTTTTGGCCCTTT
GTGTATTGCAGGTGTCTACATCCAGGCTAATCAATTTTCTAAATTACAAGCTTTGGGAGTCAAAGATTCCAAGACATTAA
GTGATAAAACAATTAGACAATTAGCTTCTCAGATTAAAAATCTTTGCCTTTATCACATCGTCAAAATTAATCCGGCAAAA
TATAATGAAATTTATCAAGATTTCAAAAATTTAAATCATTTGTTGGCCTGGGGGCATGCCACGACTATTGAACAATTGAT
CCTTCAATCCGGCTGTCAAACAGTGATTGTTGACCAGTTTGCCGATGAAAAAGTAGTTTTATTGGCTTTAAAGCGAAAAA
AATTAGATGTGAACCTCACTCAAAGGCATCGAGCAGAAGATGATTTAGCCGTCGCTGCCGCATCCATTTTAGCTAGACAA
GCCTTTATTGATGGACTTGAACAACTAAGTAAAGAAATCCAAATTCCACTTCCTAAAGGAAGCTCTTCTGCCACACAAAA
GGCTGGAAAAGAAGTATTAAGAAAATGGGGTGAAGAAAGATTAAGAAGCATCTGTAAGCAACATTTTAAAACTCTTGACG
CAATTTTAGGTAAAGTCGGAAAATAG

Upstream 100 bases:

>100_bases
GATAAAGTTTTTTGCAGTTAATATTTAATTTCGTCTGCGCTTTGCAAATGCGTATTCGCAGCTAGTGAAATTCCTTTTTT
AGATGATTAATTTACACCTC

Downstream 100 bases:

>100_bases
TGGCAAGAATTAGACCTTCTAACAAAATAAGTTGAAAAGTTAACATCTCGTTAGCCTTTCACTAACCAAATAATGATTAA
ATTGCAGGTCGTGCATGACA

Product: ribonuclease HIII

Products: NA

Alternate protein names: RNase HIII

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSSLPPFVTTLDLKLAEKLLKDLQQQGFSITIPAYTRFSASKKGLTCTLYTSGKLVVQGKEQAHFIEFYLEPEILESFGF
SHPTTKIDLTPHIGIDESGKGDFFGPLCIAGVYIQANQFSKLQALGVKDSKTLSDKTIRQLASQIKNLCLYHIVKINPAK
YNEIYQDFKNLNHLLAWGHATTIEQLILQSGCQTVIVDQFADEKVVLLALKRKKLDVNLTQRHRAEDDLAVAAASILARQ
AFIDGLEQLSKEIQIPLPKGSSSATQKAGKEVLRKWGEERLRSICKQHFKTLDAILGKVGK

Sequences:

>Translated_301_residues
MSSLPPFVTTLDLKLAEKLLKDLQQQGFSITIPAYTRFSASKKGLTCTLYTSGKLVVQGKEQAHFIEFYLEPEILESFGF
SHPTTKIDLTPHIGIDESGKGDFFGPLCIAGVYIQANQFSKLQALGVKDSKTLSDKTIRQLASQIKNLCLYHIVKINPAK
YNEIYQDFKNLNHLLAWGHATTIEQLILQSGCQTVIVDQFADEKVVLLALKRKKLDVNLTQRHRAEDDLAVAAASILARQ
AFIDGLEQLSKEIQIPLPKGSSSATQKAGKEVLRKWGEERLRSICKQHFKTLDAILGKVGK
>Mature_300_residues
SSLPPFVTTLDLKLAEKLLKDLQQQGFSITIPAYTRFSASKKGLTCTLYTSGKLVVQGKEQAHFIEFYLEPEILESFGFS
HPTTKIDLTPHIGIDESGKGDFFGPLCIAGVYIQANQFSKLQALGVKDSKTLSDKTIRQLASQIKNLCLYHIVKINPAKY
NEIYQDFKNLNHLLAWGHATTIEQLILQSGCQTVIVDQFADEKVVLLALKRKKLDVNLTQRHRAEDDLAVAAASILARQA
FIDGLEQLSKEIQIPLPKGSSSATQKAGKEVLRKWGEERLRSICKQHFKTLDAILGKVGK

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG1039

COG function: function code L; Ribonuclease HIII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family. RnhC subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH3_PARUW (Q6MDE6)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007678.1
- ProteinModelPortal:   Q6MDE6
- SMR:   Q6MDE6
- STRING:   Q6MDE6
- GeneID:   2780480
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0679
- NMPDR:   fig|264201.1.peg.679
- eggNOG:   COG1039
- HOGENOM:   HBG549406
- OMA:   ASIIARY
- ProtClustDB:   PRK00996
- BioCyc:   CPRO264201:PC0679-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00053
- InterPro:   IPR001352
- InterPro:   IPR004641
- InterPro:   IPR012337
- PIRSF:   PIRSF037748
- TIGRFAMs:   TIGR00716

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 33525; Mature: 33394

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLPPFVTTLDLKLAEKLLKDLQQQGFSITIPAYTRFSASKKGLTCTLYTSGKLVVQGK
CCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCHHCCCCCCCCCEEEEEECCEEEEECC
EQAHFIEFYLEPEILESFGFSHPTTKIDLTPHIGIDESGKGDFFGPLCIAGVYIQANQFS
CCCEEEHEEECHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHEEECCCCH
KLQALGVKDSKTLSDKTIRQLASQIKNLCLYHIVKINPAKYNEIYQDFKNLNHLLAWGHA
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCH
TTIEQLILQSGCQTVIVDQFADEKVVLLALKRKKLDVNLTQRHRAEDDLAVAAASILARQ
HHHHHHHHHCCCCEEEEHHCCCCCEEEEEEHHHCCCCCHHHHHCCHHHHHHHHHHHHHHH
AFIDGLEQLSKEIQIPLPKGSSSATQKAGKEVLRKWGEERLRSICKQHFKTLDAILGKVG
HHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
K
C
>Mature Secondary Structure 
SSLPPFVTTLDLKLAEKLLKDLQQQGFSITIPAYTRFSASKKGLTCTLYTSGKLVVQGK
CCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCHHCCCCCCCCCEEEEEECCEEEEECC
EQAHFIEFYLEPEILESFGFSHPTTKIDLTPHIGIDESGKGDFFGPLCIAGVYIQANQFS
CCCEEEHEEECHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHEEECCCCH
KLQALGVKDSKTLSDKTIRQLASQIKNLCLYHIVKINPAKYNEIYQDFKNLNHLLAWGHA
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCH
TTIEQLILQSGCQTVIVDQFADEKVVLLALKRKKLDVNLTQRHRAEDDLAVAAASILARQ
HHHHHHHHHCCCCEEEEHHCCCCCEEEEEEHHHCCCCCHHHHHCCHHHHHHHHHHHHHHH
AFIDGLEQLSKEIQIPLPKGSSSATQKAGKEVLRKWGEERLRSICKQHFKTLDAILGKVG
HHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA