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The map label for this gene is dinG [H]

Identifier: 46445810

GI number: 46445810

Start: 264440

End: 266701

Strand: Reverse

Name: dinG [H]

Synonym: pc0176

Alternate gene names: 46445810

Gene position: 266701-264440 (Counterclockwise)

Preceding gene: 46445811

Following gene: 46445809

Centisome position: 11.05

GC content: 38.37

Gene sequence:

>2262_bases
ATGTCTCATTCTCAATTACAAAGCCGAGGTCTTCAATCAGAGAAAATTCTTTCACTTCTTAAACCTGATGGATTACTTGC
TAATAGCTTAAAAGGCTTTGAATTTCGTCCCCAGCAACAGCAGATGATGACAAATATTATCGAGGCGTACAATAATGATT
CGATTGCTCTCATCGAAGCTGGAACAGGAATAGGTAAAAGTCTAGCTTACTTGATTCCGGCTTTAATTTGGGCAGCACGT
TTCAATGAACGCACTGTCATCTCGACCAATACCATTACTCTTCAGGAGCAGCTTTTATCAAAAGACATTCCAAACCTTTT
AGACGCACTTGATTTGAATTTGAAAGCGGTACTTGTTAAAGGAATGCATAATTATCTTTGTATTCGTAAACTAGAAGATG
TTCAGATGGAAATGAGCATTGTCTCTTCAGAAGAAGCCCAAGAAATTGAGAAAATTGAGGCTTGGCGCCAACAAACAGTT
GATGGATCGCGCTCTTCACTTTCTTTCGCTCCGACTCATTCTGTTTGGGAGAAAGTTGGAGCAGAAAATGAAGCGTGCTC
TCATCATGAATGTCCTCATTACCAGCAATGTTTCTTTTTTAAAGCTAGACGCCAAGCACAAGATGCGCACATCTTAATTG
TGAATCACCACCTCTTATTTGCTGATCTTATGCGCCGAGCAGACACTGCCAATTACAGCGAAACAAGCATTCTTCCCACC
TATCGCAGAATTATTTTAGATGAAGCTCATCATGTTGAAGATATTGCTACAGAATATTTTGCTTCACATTTACATCGTAT
TGAGTTGATGCGCACAATGGGTCGCTTAGGTTCTGAAAGGCATAGTCAACAACCAGGTAAACTTCCTATTTTAAAAGAGA
AACTGCAACTTTTATATAATAAAACTCCACCGCGAGAAATTAGTCAAATCGTGATGCGCTTGACAATAGATTTACCTGCT
CTTCGCCATGTCATCCATGAACAAATTAACCAAACATTTGATGCCTTTGCTCACTTTATTGAAGCGATCAAAAACCCTGC
CTCTCGGTTATTAGGCGAAGAAGTGTCTTTAAATGAGCAGAAACTACGCATTTTGAACGAACATATGAACCACACAAAGT
GGAAAGAGGAAATTCATCCCTCTGCTAGTCAGCTTATCGATTCTCTTAAAAACTATCGTCTAAACATTACTAATTTAGAG
GCTGAACTTAAATTAATTGAAAATGAACGATTGCAAGAACAAACTAAAAGTATTCGGTTAGATATTCAAGGTCTTGCCAA
TCGGCTAGAAACTTCAATTTCTTTGCTTAATCACTTTATTTTGCCCCCTTCTTCACCCAATAAAGTGCGTTGGATCGAAG
CTCACAAATTGAAATCTTTAATCAATGTACACTTAGTAGATGCAGATTTAGACATTTCGAAATCGCTAGCTGAATTTGTA
TTTAGCAAATTTCCTACCGTTATTTTATGTAGCGCGACATTAACTTCTAATCAACAATTTCAGTTTATTCGTAAGCGTTT
AGGATTAACCGATAAGCACCTTCCTTATAGACAAATTGAAGAATATATTTATGATTCTCCTTTCGACTACCATAAACAAG
CACTACTAGCTGTTCCCACGGATATGCCTCCCCCATCGCACCCAGATTTTAATTGGATTGCTTTTGAAAACATTTGGAAA
GCTATTCAAGCTAGCCGTGGACAAGCCTTTGTCCTTTTCACCTCTTACTCTATGTTGCAACAGTGTGCGGAGAAATTATC
AGCTCGTATGCATGAGCATGCATATGTCTTATTTAAACAAGGGGAAGAAGCGAGGCAGACGTTATTACATAAATTTAAAA
CGACAGATCGAGCCATTTTATTTGGTACAGATTCTTTCTGGGAAGGAGTGGATGTCGCTGGTGATGCACTTCGATGTGTC
ATTATTGTCAAACTTCCTTTTAGAGTTCCTACTGAGCCGCTCATTCAAGCACGCACAGAAGCCATTATCGAAAAAGGAGG
AGAGCCATTTTTTGAATATTCCGTTCCTCAGGCAGTTGTCAAATTTAAACAAGGCTTTGGACGATTGATTCGCAATCAAT
GGGATCGAGGATGTATTGTCTGTTTAGATACTCGATTAGTTACAAAAGGATACGGAAAGCAATTTTTAAACAGTCTTCCT
GCCTGTGAAAAAGTTTTTATTAATAGCGAGCAGTTGTGGGCAAAAATGGGAGATTTTTATCGAAAAACTTACCATTTGGT
CAAACAAAATCCATTCTCCTAA

Upstream 100 bases:

>100_bases
CTCAAAGCCTTCCTTGATTTATTAGAAGCAGAATAAATTAATATCCTCTCTTAATAAAAGAGGGGATATTTGTCTTGTAA
CCTTAGGCTCCATTTTTAAT

Downstream 100 bases:

>100_bases
GTCATCTAGGAATCAATCAGTATTAAAACTTAAGCCTTAGTGCAGCTTATATAGACTTGTTCATTGCGGTTGATGAAAAT
TTTATTCAATCGAACTTCAA

Product: putative ATP-dependent DNA helicase dinG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 753; Mature: 752

Protein sequence:

>753_residues
MSHSQLQSRGLQSEKILSLLKPDGLLANSLKGFEFRPQQQQMMTNIIEAYNNDSIALIEAGTGIGKSLAYLIPALIWAAR
FNERTVISTNTITLQEQLLSKDIPNLLDALDLNLKAVLVKGMHNYLCIRKLEDVQMEMSIVSSEEAQEIEKIEAWRQQTV
DGSRSSLSFAPTHSVWEKVGAENEACSHHECPHYQQCFFFKARRQAQDAHILIVNHHLLFADLMRRADTANYSETSILPT
YRRIILDEAHHVEDIATEYFASHLHRIELMRTMGRLGSERHSQQPGKLPILKEKLQLLYNKTPPREISQIVMRLTIDLPA
LRHVIHEQINQTFDAFAHFIEAIKNPASRLLGEEVSLNEQKLRILNEHMNHTKWKEEIHPSASQLIDSLKNYRLNITNLE
AELKLIENERLQEQTKSIRLDIQGLANRLETSISLLNHFILPPSSPNKVRWIEAHKLKSLINVHLVDADLDISKSLAEFV
FSKFPTVILCSATLTSNQQFQFIRKRLGLTDKHLPYRQIEEYIYDSPFDYHKQALLAVPTDMPPPSHPDFNWIAFENIWK
AIQASRGQAFVLFTSYSMLQQCAEKLSARMHEHAYVLFKQGEEARQTLLHKFKTTDRAILFGTDSFWEGVDVAGDALRCV
IIVKLPFRVPTEPLIQARTEAIIEKGGEPFFEYSVPQAVVKFKQGFGRLIRNQWDRGCIVCLDTRLVTKGYGKQFLNSLP
ACEKVFINSEQLWAKMGDFYRKTYHLVKQNPFS

Sequences:

>Translated_753_residues
MSHSQLQSRGLQSEKILSLLKPDGLLANSLKGFEFRPQQQQMMTNIIEAYNNDSIALIEAGTGIGKSLAYLIPALIWAAR
FNERTVISTNTITLQEQLLSKDIPNLLDALDLNLKAVLVKGMHNYLCIRKLEDVQMEMSIVSSEEAQEIEKIEAWRQQTV
DGSRSSLSFAPTHSVWEKVGAENEACSHHECPHYQQCFFFKARRQAQDAHILIVNHHLLFADLMRRADTANYSETSILPT
YRRIILDEAHHVEDIATEYFASHLHRIELMRTMGRLGSERHSQQPGKLPILKEKLQLLYNKTPPREISQIVMRLTIDLPA
LRHVIHEQINQTFDAFAHFIEAIKNPASRLLGEEVSLNEQKLRILNEHMNHTKWKEEIHPSASQLIDSLKNYRLNITNLE
AELKLIENERLQEQTKSIRLDIQGLANRLETSISLLNHFILPPSSPNKVRWIEAHKLKSLINVHLVDADLDISKSLAEFV
FSKFPTVILCSATLTSNQQFQFIRKRLGLTDKHLPYRQIEEYIYDSPFDYHKQALLAVPTDMPPPSHPDFNWIAFENIWK
AIQASRGQAFVLFTSYSMLQQCAEKLSARMHEHAYVLFKQGEEARQTLLHKFKTTDRAILFGTDSFWEGVDVAGDALRCV
IIVKLPFRVPTEPLIQARTEAIIEKGGEPFFEYSVPQAVVKFKQGFGRLIRNQWDRGCIVCLDTRLVTKGYGKQFLNSLP
ACEKVFINSEQLWAKMGDFYRKTYHLVKQNPFS
>Mature_752_residues
SHSQLQSRGLQSEKILSLLKPDGLLANSLKGFEFRPQQQQMMTNIIEAYNNDSIALIEAGTGIGKSLAYLIPALIWAARF
NERTVISTNTITLQEQLLSKDIPNLLDALDLNLKAVLVKGMHNYLCIRKLEDVQMEMSIVSSEEAQEIEKIEAWRQQTVD
GSRSSLSFAPTHSVWEKVGAENEACSHHECPHYQQCFFFKARRQAQDAHILIVNHHLLFADLMRRADTANYSETSILPTY
RRIILDEAHHVEDIATEYFASHLHRIELMRTMGRLGSERHSQQPGKLPILKEKLQLLYNKTPPREISQIVMRLTIDLPAL
RHVIHEQINQTFDAFAHFIEAIKNPASRLLGEEVSLNEQKLRILNEHMNHTKWKEEIHPSASQLIDSLKNYRLNITNLEA
ELKLIENERLQEQTKSIRLDIQGLANRLETSISLLNHFILPPSSPNKVRWIEAHKLKSLINVHLVDADLDISKSLAEFVF
SKFPTVILCSATLTSNQQFQFIRKRLGLTDKHLPYRQIEEYIYDSPFDYHKQALLAVPTDMPPPSHPDFNWIAFENIWKA
IQASRGQAFVLFTSYSMLQQCAEKLSARMHEHAYVLFKQGEEARQTLLHKFKTTDRAILFGTDSFWEGVDVAGDALRCVI
IVKLPFRVPTEPLIQARTEAIIEKGGEPFFEYSVPQAVVKFKQGFGRLIRNQWDRGCIVCLDTRLVTKGYGKQFLNSLPA
CEKVFINSEQLWAKMGDFYRKTYHLVKQNPFS

Specific function: Probable helicase involved in DNA repair and perhaps also replication [H]

COG id: COG1199

COG function: function code KL; Rad3-related DNA helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788110, Length=251, Percent_Identity=40.6374501992032, Blast_Score=182, Evalue=7e-47,
Organism=Escherichia coli, GI1787018, Length=257, Percent_Identity=29.1828793774319, Blast_Score=108, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR006054
- InterPro:   IPR006310
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR014013
- InterPro:   IPR006555
- InterPro:   IPR001650
- InterPro:   IPR006935
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 86582; Mature: 86450

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSQLQSRGLQSEKILSLLKPDGLLANSLKGFEFRPQQQQMMTNIIEAYNNDSIALIEA
CCCHHHHHCCCCHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEC
GTGIGKSLAYLIPALIWAARFNERTVISTNTITLQEQLLSKDIPNLLDALDLNLKAVLVK
CCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHH
GMHNYLCIRKLEDVQMEMSIVSSEEAQEIEKIEAWRQQTVDGSRSSLSFAPTHSVWEKVG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHC
AENEACSHHECPHYQQCFFFKARRQAQDAHILIVNHHLLFADLMRRADTANYSETSILPT
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCCHHHH
YRRIILDEAHHVEDIATEYFASHLHRIELMRTMGRLGSERHSQQPGKLPILKEKLQLLYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHC
KTPPREISQIVMRLTIDLPALRHVIHEQINQTFDAFAHFIEAIKNPASRLLGEEVSLNEQ
CCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHH
KLRILNEHMNHTKWKEEIHPSASQLIDSLKNYRLNITNLEAELKLIENERLQEQTKSIRL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCEEEEEEHHHHHHHHHHHHHHHHHHHHHH
DIQGLANRLETSISLLNHFILPPSSPNKVRWIEAHKLKSLINVHLVDADLDISKSLAEFV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHEEEEECCCCHHHHHHHHH
FSKFPTVILCSATLTSNQQFQFIRKRLGLTDKHLPYRQIEEYIYDSPFDYHKQALLAVPT
HHHCCCEEEEECHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHCCEEEECCC
DMPPPSHPDFNWIAFENIWKAIQASRGQAFVLFTSYSMLQQCAEKLSARMHEHAYVLFKQ
CCCCCCCCCCCEEHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHEEEEEC
GEEARQTLLHKFKTTDRAILFGTDSFWEGVDVAGDALRCVIIVKLPFRVPTEPLIQARTE
CHHHHHHHHHHHCCCCCEEEEECCHHHCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHH
AIIEKGGEPFFEYSVPQAVVKFKQGFGRLIRNQWDRGCIVCLDTRLVTKGYGKQFLNSLP
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHCC
ACEKVFINSEQLWAKMGDFYRKTYHLVKQNPFS
CHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SHSQLQSRGLQSEKILSLLKPDGLLANSLKGFEFRPQQQQMMTNIIEAYNNDSIALIEA
CCHHHHHCCCCHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEC
GTGIGKSLAYLIPALIWAARFNERTVISTNTITLQEQLLSKDIPNLLDALDLNLKAVLVK
CCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHH
GMHNYLCIRKLEDVQMEMSIVSSEEAQEIEKIEAWRQQTVDGSRSSLSFAPTHSVWEKVG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHC
AENEACSHHECPHYQQCFFFKARRQAQDAHILIVNHHLLFADLMRRADTANYSETSILPT
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCCHHHH
YRRIILDEAHHVEDIATEYFASHLHRIELMRTMGRLGSERHSQQPGKLPILKEKLQLLYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHC
KTPPREISQIVMRLTIDLPALRHVIHEQINQTFDAFAHFIEAIKNPASRLLGEEVSLNEQ
CCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHH
KLRILNEHMNHTKWKEEIHPSASQLIDSLKNYRLNITNLEAELKLIENERLQEQTKSIRL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCEEEEEEHHHHHHHHHHHHHHHHHHHHHH
DIQGLANRLETSISLLNHFILPPSSPNKVRWIEAHKLKSLINVHLVDADLDISKSLAEFV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHEEEEECCCCHHHHHHHHH
FSKFPTVILCSATLTSNQQFQFIRKRLGLTDKHLPYRQIEEYIYDSPFDYHKQALLAVPT
HHHCCCEEEEECHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHCCEEEECCC
DMPPPSHPDFNWIAFENIWKAIQASRGQAFVLFTSYSMLQQCAEKLSARMHEHAYVLFKQ
CCCCCCCCCCCEEHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHEEEEEC
GEEARQTLLHKFKTTDRAILFGTDSFWEGVDVAGDALRCVIIVKLPFRVPTEPLIQARTE
CHHHHHHHHHHHCCCCCEEEEECCHHHCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHH
AIIEKGGEPFFEYSVPQAVVKFKQGFGRLIRNQWDRGCIVCLDTRLVTKGYGKQFLNSLP
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHCC
ACEKVFINSEQLWAKMGDFYRKTYHLVKQNPFS
CHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]