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The map label for this gene is kdsB [H]

Identifier: 45658006

GI number: 45658006

Start: 2607840

End: 2608595

Strand: Reverse

Name: kdsB [H]

Synonym: LIC12157

Alternate gene names: 45658006

Gene position: 2608595-2607840 (Counterclockwise)

Preceding gene: 45658007

Following gene: 45658005

Centisome position: 60.99

GC content: 41.53

Gene sequence:

>756_bases
ATGAAAACGATTGCTGTTTTGCCGGCGAGAATGGCCTCTTCCAGGTTTCCCGATAAACCGTTGGTCAAGATCTCTGGGTT
AGAAATGATAGAACACGTCAGACGTAGGGTAGAAATGTCTTCTTCCGTTGATGAGGTAGTTGTAGCTACTTGCGACGAAA
TTATCAAACAAAGAGTAGAATCTTTTGGCGGAAAAGCTGTGATGACTTCGGATGTTCATAGGGGTTGTATTGACCGGGTT
GCAGAGGCAGCTCTCTACGTAGAAGGAGATATCGTTATCGTCGTCCAAGGAGACGAGCCCTTGATTTTACCGGCGATGCT
GGATGATTTAGTCAAACCGATGTTAAACGACTCTTCAATTTATTGTACAAATTTAGTTACAAAAATTGTAGATGAAGAAG
AGTTTCAAAGTCCGAACGCTCCTAAGGTCGTTGTTGATAAAAATTGGGATCTACTTTATGCTTCGAGAGAACCGATTCCG
TCTAGAAAAAAATATCCGAATGAGGATTATTTAAAGCTTAAGCAACTAGGAGTGATTGCGTTTCGAAATGATTTTTTGCA
AACGTTTGCCGCCCTTGCGCCAACACCTCTGGAAATTATTGAATCTGTAGATATGAATCGTGCGGTAGAACATGGTTATA
AGGTGAGAATGGTTCTTACGGAAGGAATTATGATCGGAGTTGACGTCCCAGGAGACGTTTCCAGAGTCGAGTCCGTTTTT
AAAACGGACTTGTTGCTATCGAAGTATTTATCATAA

Upstream 100 bases:

>100_bases
GCCTATTCTACGGATGCGATTATGTTAAATACGCAAGCTAGTTTGAATTTTGAAGAATTAAAATAGTTTAAAATTATTAA
TTACTAATTTTGGAATAAAT

Downstream 100 bases:

>100_bases
GTATGAAGAAGCTTAAAGTTGGTATTACAGGATATGGGGTCGTAGGAAAACGCAGGCACCAATATATCAAACAAAATCCT
AATTTAATGGTTACTGCAAT

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MKTIAVLPARMASSRFPDKPLVKISGLEMIEHVRRRVEMSSSVDEVVVATCDEIIKQRVESFGGKAVMTSDVHRGCIDRV
AEAALYVEGDIVIVVQGDEPLILPAMLDDLVKPMLNDSSIYCTNLVTKIVDEEEFQSPNAPKVVVDKNWDLLYASREPIP
SRKKYPNEDYLKLKQLGVIAFRNDFLQTFAALAPTPLEIIESVDMNRAVEHGYKVRMVLTEGIMIGVDVPGDVSRVESVF
KTDLLLSKYLS

Sequences:

>Translated_251_residues
MKTIAVLPARMASSRFPDKPLVKISGLEMIEHVRRRVEMSSSVDEVVVATCDEIIKQRVESFGGKAVMTSDVHRGCIDRV
AEAALYVEGDIVIVVQGDEPLILPAMLDDLVKPMLNDSSIYCTNLVTKIVDEEEFQSPNAPKVVVDKNWDLLYASREPIP
SRKKYPNEDYLKLKQLGVIAFRNDFLQTFAALAPTPLEIIESVDMNRAVEHGYKVRMVLTEGIMIGVDVPGDVSRVESVF
KTDLLLSKYLS
>Mature_251_residues
MKTIAVLPARMASSRFPDKPLVKISGLEMIEHVRRRVEMSSSVDEVVVATCDEIIKQRVESFGGKAVMTSDVHRGCIDRV
AEAALYVEGDIVIVVQGDEPLILPAMLDDLVKPMLNDSSIYCTNLVTKIVDEEEFQSPNAPKVVVDKNWDLLYASREPIP
SRKKYPNEDYLKLKQLGVIAFRNDFLQTFAALAPTPLEIIESVDMNRAVEHGYKVRMVLTEGIMIGVDVPGDVSRVESVF
KTDLLLSKYLS

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=247, Percent_Identity=34.0080971659919, Blast_Score=127, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 28027; Mature: 28027

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIAVLPARMASSRFPDKPLVKISGLEMIEHVRRRVEMSSSVDEVVVATCDEIIKQRVE
CCCEEECHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
SFGGKAVMTSDVHRGCIDRVAEAALYVEGDIVIVVQGDEPLILPAMLDDLVKPMLNDSSI
HCCCCEEEHHHHHHHHHHHHHHHHEEECCCEEEEEECCCCEEHHHHHHHHHHHHHCCCCC
YCTNLVTKIVDEEEFQSPNAPKVVVDKNWDLLYASREPIPSRKKYPNEDYLKLKQLGVIA
HHHHHHHHHHCHHHHCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
FRNDFLQTFAALAPTPLEIIESVDMNRAVEHGYKVRMVLTEGIMIGVDVPGDVSRVESVF
HHHHHHHHHHHHCCCHHHHHHHCCHHHHHHCCCEEEEEEECCEEEEEECCCCHHHHHHHH
KTDLLLSKYLS
HHHHHHHHHCC
>Mature Secondary Structure
MKTIAVLPARMASSRFPDKPLVKISGLEMIEHVRRRVEMSSSVDEVVVATCDEIIKQRVE
CCCEEECHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
SFGGKAVMTSDVHRGCIDRVAEAALYVEGDIVIVVQGDEPLILPAMLDDLVKPMLNDSSI
HCCCCEEEHHHHHHHHHHHHHHHHEEECCCEEEEEECCCCEEHHHHHHHHHHHHHCCCCC
YCTNLVTKIVDEEEFQSPNAPKVVVDKNWDLLYASREPIPSRKKYPNEDYLKLKQLGVIA
HHHHHHHHHHCHHHHCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
FRNDFLQTFAALAPTPLEIIESVDMNRAVEHGYKVRMVLTEGIMIGVDVPGDVSRVESVF
HHHHHHHHHHHHCCCHHHHHHHCCHHHHHHCCCEEEEEEECCEEEEEECCCCHHHHHHHH
KTDLLLSKYLS
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA