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The map label for this gene is tpn50 [H]

Identifier: 45656490

GI number: 45656490

Start: 722430

End: 723857

Strand: Direct

Name: tpn50 [H]

Synonym: LIC10592

Alternate gene names: 45656490

Gene position: 722430-723857 (Clockwise)

Preceding gene: 45656487

Following gene: 45656491

Centisome position: 16.89

GC content: 35.71

Gene sequence:

>1428_bases
TTGGAAAGTTTTTTACACTTTCCTTATGTTTTAAAGGAATCTTACGAAACTAAAACTATGGGGAAATTTTCCAATCAACC
TTCAAAATCCAAAATCATAAACAGACGTTTACGAAGAATTGTATCATACGTTTTTATTATTTCTACATTGATCGGTTTTA
CTTCTACTTTTCCAGAAGAATCGGGCAAAGTTCTCTTTCGTTGGAAACTAAAACCAGGAGAGAATGTAGAATTAAACGAA
TATCATCGAGTACAATTAGTAAGTATGGGAAAGAAAATTAGAAGAGAAGATAAAAATCGAATCCTATTACAAACCCTTTC
CTGCGAAAATAAAGAATGTACGTTAGAAGGATTTTTTGATACTTACACTCGTTTTCCCGAAGTTGATCCTGCGTTTCGTA
AAGATAAAACGTTTAAGAGCAGATTTCAAATAACAGATTTAGGTCAATATAAAGTGCCACAGGAATACAGTATGCCTAAT
CTCCGCTCTCTTCCTAGTTTTTCCGAAAAACCAATTTCCATTGGAGAAGAATGGACACAACCCGCTACGGAAAGTTTTCA
ATTTCCAGGAGGAAGGGTTATGATCACGGTTTTTGCGAAATATAAGTATCACGGTGTAGACGAATGGGAATATCAAAAGT
TGTCCGGTAAAGGAGATCGTATCGAATACAATTATAATTTATATTATGATTCTCAAATGAACAGAACCGGGGTTCCATTT
AAGATCTACGGATTTGCGCGAGGAATGGTATTTTTTGATCGCGAACTTGGAATTCCACAATATAAAAGGGTTCAGTTGTC
GTACACTTTTGTCTATGAAAATGGAATGGCGCAAGAGATGTCGTTCGACATTCACGGAGTATATAATAAAAACGTAAAAC
TTACGGATCAAGACAAGGACAAGTTTGCGGAAGAAATCCGTAAAATTTTAGGAGGAGAACTTCCAACTGGAATTGAACCA
GATTCCGATTCAAAAAAGAATTTAAAAAAACCGAAAAAGGAAACCATTTCATGGCCGGAAGAAGAGGATAATCAAGCCGC
ACCAGAAGGTTCGCCGGTAGAAATTAGAAGAACAGAAGAAGGAATCGCTATTTCTTTAAATTCAGTGTTGTTTGATCACA
ACAGCTCAGAACTTAAACAAGAAGCAAAATTAGAATTAAAAAGAATCGCATCCGTATTGAAAAAATATGCAGATAGAGAA
ATCAGAATTAGCGGGCATACTGACAATTCAGGCGGGGAGGAATATAATCGAAAACTTTCCAGAGAAAGAGCACTTTCCGT
TTTGAAGGAACTCAGAGATGAACAAGGTTTGGAAGAAAAAAGAATGTCTTACGAAGGATATGGGAAATCAAAACCGATTG
CAGATAACTCTACGATTCAAGGTAGGCAAAAAAATCGTAGGGTAGATATTACTATTGTAATGGAATAA

Upstream 100 bases:

>100_bases
TGCTCGTCGTAACGTAAACAAGTCTCGCTTCCATTGGGATTCTCCTTAACGTAAATAAATCGGAAATTCAGTTTTAAATT
TCGTCCTAAATTCGTATTTT

Downstream 100 bases:

>100_bases
GTTAAAAAAATAAAATATTATTAGAAAAAAGTTATTTCATAAAATATATTATCATTGTTGCATTAAAAGAATCGACTAAC
GTTAAGTAATACGTTTTTCT

Product: peptidoglycan-associated cytoplasmic membrane protein

Products: NA

Alternate protein names: Antigen tpp57 [H]

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MESFLHFPYVLKESYETKTMGKFSNQPSKSKIINRRLRRIVSYVFIISTLIGFTSTFPEESGKVLFRWKLKPGENVELNE
YHRVQLVSMGKKIRREDKNRILLQTLSCENKECTLEGFFDTYTRFPEVDPAFRKDKTFKSRFQITDLGQYKVPQEYSMPN
LRSLPSFSEKPISIGEEWTQPATESFQFPGGRVMITVFAKYKYHGVDEWEYQKLSGKGDRIEYNYNLYYDSQMNRTGVPF
KIYGFARGMVFFDRELGIPQYKRVQLSYTFVYENGMAQEMSFDIHGVYNKNVKLTDQDKDKFAEEIRKILGGELPTGIEP
DSDSKKNLKKPKKETISWPEEEDNQAAPEGSPVEIRRTEEGIAISLNSVLFDHNSSELKQEAKLELKRIASVLKKYADRE
IRISGHTDNSGGEEYNRKLSRERALSVLKELRDEQGLEEKRMSYEGYGKSKPIADNSTIQGRQKNRRVDITIVME

Sequences:

>Translated_475_residues
MESFLHFPYVLKESYETKTMGKFSNQPSKSKIINRRLRRIVSYVFIISTLIGFTSTFPEESGKVLFRWKLKPGENVELNE
YHRVQLVSMGKKIRREDKNRILLQTLSCENKECTLEGFFDTYTRFPEVDPAFRKDKTFKSRFQITDLGQYKVPQEYSMPN
LRSLPSFSEKPISIGEEWTQPATESFQFPGGRVMITVFAKYKYHGVDEWEYQKLSGKGDRIEYNYNLYYDSQMNRTGVPF
KIYGFARGMVFFDRELGIPQYKRVQLSYTFVYENGMAQEMSFDIHGVYNKNVKLTDQDKDKFAEEIRKILGGELPTGIEP
DSDSKKNLKKPKKETISWPEEEDNQAAPEGSPVEIRRTEEGIAISLNSVLFDHNSSELKQEAKLELKRIASVLKKYADRE
IRISGHTDNSGGEEYNRKLSRERALSVLKELRDEQGLEEKRMSYEGYGKSKPIADNSTIQGRQKNRRVDITIVME
>Mature_475_residues
MESFLHFPYVLKESYETKTMGKFSNQPSKSKIINRRLRRIVSYVFIISTLIGFTSTFPEESGKVLFRWKLKPGENVELNE
YHRVQLVSMGKKIRREDKNRILLQTLSCENKECTLEGFFDTYTRFPEVDPAFRKDKTFKSRFQITDLGQYKVPQEYSMPN
LRSLPSFSEKPISIGEEWTQPATESFQFPGGRVMITVFAKYKYHGVDEWEYQKLSGKGDRIEYNYNLYYDSQMNRTGVPF
KIYGFARGMVFFDRELGIPQYKRVQLSYTFVYENGMAQEMSFDIHGVYNKNVKLTDQDKDKFAEEIRKILGGELPTGIEP
DSDSKKNLKKPKKETISWPEEEDNQAAPEGSPVEIRRTEEGIAISLNSVLFDHNSSELKQEAKLELKRIASVLKKYADRE
IRISGHTDNSGGEEYNRKLSRERALSVLKELRDEQGLEEKRMSYEGYGKSKPIADNSTIQGRQKNRRVDITIVME

Specific function: Could function as a porin [H]

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI48994946, Length=124, Percent_Identity=38.7096774193548, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788957, Length=107, Percent_Identity=34.5794392523364, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006664
- InterPro:   IPR006690
- InterPro:   IPR006665 [H]

Pfam domain/function: PF00691 OmpA [H]

EC number: NA

Molecular weight: Translated: 55338; Mature: 55338

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESFLHFPYVLKESYETKTMGKFSNQPSKSKIINRRLRRIVSYVFIISTLIGFTSTFPEE
CCCCCCCCHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SGKVLFRWKLKPGENVELNEYHRVQLVSMGKKIRREDKNRILLQTLSCENKECTLEGFFD
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEHHHH
TYTRFPEVDPAFRKDKTFKSRFQITDLGQYKVPQEYSMPNLRSLPSFSEKPISIGEEWTQ
HHHCCCCCCCCHHCCCHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCC
PATESFQFPGGRVMITVFAKYKYHGVDEWEYQKLSGKGDRIEYNYNLYYDSQMNRTGVPF
CCHHCCCCCCCEEEEEEEEEEEECCCCCHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCE
KIYGFARGMVFFDRELGIPQYKRVQLSYTFVYENGMAQEMSFDIHGVYNKNVKLTDQDKD
EEEEEECCEEEEECCCCCCCEEEEEEEEEEEEECCCCHHHCEEEEEEECCCEEECCCHHH
KFAEEIRKILGGELPTGIEPDSDSKKNLKKPKKETISWPEEEDNQAAPEGSPVEIRRTEE
HHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCC
GIAISLNSVLFDHNSSELKQEAKLELKRIASVLKKYADREIRISGHTDNSGGEEYNRKLS
CEEEEEEHEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHH
RERALSVLKELRDEQGLEEKRMSYEGYGKSKPIADNSTIQGRQKNRRVDITIVME
HHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEC
>Mature Secondary Structure
MESFLHFPYVLKESYETKTMGKFSNQPSKSKIINRRLRRIVSYVFIISTLIGFTSTFPEE
CCCCCCCCHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SGKVLFRWKLKPGENVELNEYHRVQLVSMGKKIRREDKNRILLQTLSCENKECTLEGFFD
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEHHHH
TYTRFPEVDPAFRKDKTFKSRFQITDLGQYKVPQEYSMPNLRSLPSFSEKPISIGEEWTQ
HHHCCCCCCCCHHCCCHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCC
PATESFQFPGGRVMITVFAKYKYHGVDEWEYQKLSGKGDRIEYNYNLYYDSQMNRTGVPF
CCHHCCCCCCCEEEEEEEEEEEECCCCCHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCE
KIYGFARGMVFFDRELGIPQYKRVQLSYTFVYENGMAQEMSFDIHGVYNKNVKLTDQDKD
EEEEEECCEEEEECCCCCCCEEEEEEEEEEEEECCCCHHHCEEEEEEECCCEEECCCHHH
KFAEEIRKILGGELPTGIEPDSDSKKNLKKPKKETISWPEEEDNQAAPEGSPVEIRRTEE
HHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCC
GIAISLNSVLFDHNSSELKQEAKLELKRIASVLKKYADREIRISGHTDNSGGEEYNRKLS
CEEEEEEHEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHH
RERALSVLKELRDEQGLEEKRMSYEGYGKSKPIADNSTIQGRQKNRRVDITIVME
HHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8112835; 7623668; 9665876 [H]