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The map label for this gene is amt3

Identifier: 45656487

GI number: 45656487

Start: 717451

End: 719907

Strand: Direct

Name: amt3

Synonym: LIC10589

Alternate gene names: 45656487

Gene position: 717451-719907 (Clockwise)

Preceding gene: 45656486

Following gene: 45656490

Centisome position: 16.77

GC content: 38.46

Gene sequence:

>2457_bases
TTGGAAAGAATTTATTTTGGAATTTACCCTACAACCAGGAACTCGAAGAAACGAAGCCCTAGGAAAACTTCACCTATAAA
ACTTCGAAAGAATGAATCATTTGGAAACTTTATGAAAAACCGCGTTGCAAACAGAATCGTTTTAATACTTTTTTTAGGAA
TTAACCTTCCGTTATTTTCTGAATCTCCAGCCTTGGAATTATCTAAGACCGTGGATCCGATTTGGCTCATCCTATGCGCA
GCTTTGGTGTTTTTTATGCAGGCTGGATTTTTGATGTTGGAAACCGGACTTTCTAGACTAAAAAATACAATCAACGTAGC
TGTAAAAAATCTTATGGATTATATCGTAGGAACGATCGCGTTTTTCTCCGTAGGTTTTGCATTGATGTTTGGACTTTCCT
ATGAAGGTTGGATAGGAACTAATCATTTCTTTTTAACCGGTTTAAAAACCGGTAAAGATTTTTCCTTTTTTTTATTCCAA
GTCGCGTTTATGGGAACGGCGGCGACAATTGTTTCTGGAGCGGTTGCCGAACGTATTAAATTTTCTGCATATTTAATCGT
ATCGGTTGTGGTTTCATTATTTATCTATCCGGTTTTTGGGCATTGGACTTGGGGAGGAGGTTGGATCGCAAAGATCGGTT
TTGTGGACTTTGCTGGTTCTACCGTTGTGCACTCGTTAGGTGGTTGGATCGCTTTGGCTGGAGTGATCGTTTTAGGACCT
AGAAAGGACAAATTTAAAGAAGACGGTACTCCTAGAAAAATTCATGGACATAATCTAACCTTTTCGGTGTTAGGCGTTTT
TATACTTTGGTTTGGATGGTTCGGATTTAACGGAGGAAGTGCACTTTCTTTTACGGATCAAGTTCCTTTGATCATTTTGA
ATACAAGTCTTGCCGGAAGTGTCGGAGGAATTTTTGCGATCACTTTTTCTTGGATTTTTTATAGAGTTGCATCGGTAGAA
GACTGCATGAATGGAGTGTTAGGTGGTCTGGTCGCAATAACTGCCGGTTGTCACGCTTTTCAGCCCTACGCATCTTTGAT
AGTAGGTGCTCTCGCTGGAATTTCTGTTGTGATTACTTCTTGGGTATTAGAAAAAATTCTAAAGTTAGACGATGTGGTAG
GGGCGTTTCCGGTTCACGGAGTCTGTGGAATTATAGGGACACTTTTATTACCAATTCTATCAGAAAATCAAGATATTCGA
ATATACCCTCAATTCATTGGAGTTTTAACCTGTTCTTTCTGGGCTTTCGGTTTGGGGATGATATTGTTTTTGCTATTGAA
GATTTCAATCGGAATCAGAGTGAACGAAGAATTTGAAGAAAAAGGACTGAATGTTACGGAGCACGGAGCAGGTTCCAGTT
GGATCGATCTTATACATTCTCTTAAGGATCTCGCCAAAGGAGGAGGCGATTTGACCCGGAAGATTCACGTAGATTCAGGA
ACAGAAGCGGGAGCGATTGCGTTTTTGATGAATCGTTATCTCGCAAATTTAGGGCAGATGATTTATACGATCAAAGAAAA
GTCTATCGAATTGGAATATTCTTCTTCCGAGATCTCGGTTGCTTGGGGAAAAATGAGTCAAGGAATTCAGCAACAAGCCG
CAAATTTAGGGGAAGTTACTTCTATATTCGATTCTTTTAGAGAATCTTTTCAAACAATTTCTTCTTCAGCGGCTCAACAA
AAGGAAATGGAAACAAGCGCGAGTGAATTGTTAAACGAACTCGTATTTGGATTTCAAAAGTTCGATTCCGATTTAAAAAA
TAGTTCCGAAAAATCGGAAGAATCTGTCAAAGCAATCGACCTGAGCAGGAAAGAACTCAATCAATTAGAAACCGATATTA
ACGATATAGGATCTTCCGCTAAAAAAGTAGAAGGCCTAGTAAAATTACTCAACGATATATCTACCAAATTGGGAATGTTA
TCTATTAACGCTTCTATCGAAGCTGCGCGTTCCGGAGCGGCGGGAAAAGGTTTCGGAGTGGTTGCAGAAGAAATCAGCAA
ACTCGCTTCGAGCACACAAGAAAGCACAAAAAAGGCTTCGGAAATTTTAGGTGAAATTCAATCCACGGTTTCGCGCGGAA
AAACTACGGTTCAAACTTCTGTAGAATTTTTTAAAAACTTAACGGAAGAATTTAGATTTTTAGCTGAGACATACATAACA
ATAAGAAAAAGTAGTTTACATTATTCTAATTTAATTGGGAACTTAAATCGTTTAAATACTTCCATTACAAACCAGAGTGA
AATCATCATGACGGACATAGATAAACGATTTTCTGAAATCGGTAATCTTTACGAATCTGTGGATCTTATCAACGGCGCCT
TTCATGAAATTTCTGCACAATCGGAAGAGTTGAATGCAACTGGTGAATTTTTAAAACAACTCGCTGAAATTCTAAATTCA
CTCGTCCGAAATTTTAGAGTAGAACAAAACTCTTCTCAAGAATTGATTCCTGGATAA

Upstream 100 bases:

>100_bases
GATTTCAAGAACGATCTGAATTCTCTCCATGGAAAGGTCTTCGAAAAATAGAATTATTCGATCTAAATCTGTAAAATAAA
AATCTTTTACTTTTTCGTAG

Downstream 100 bases:

>100_bases
AGTGATTTCGAAAATTTTTTTGATTTTAATAATTAGAATTATTGAAAACTTCTATAGTGGGATTGGCAAAACTGCTTCAA
TTGTCTATTTCAATACAACG

Product: ammonium transporter

Products: NH3 [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 818; Mature: 818

Protein sequence:

>818_residues
MERIYFGIYPTTRNSKKRSPRKTSPIKLRKNESFGNFMKNRVANRIVLILFLGINLPLFSESPALELSKTVDPIWLILCA
ALVFFMQAGFLMLETGLSRLKNTINVAVKNLMDYIVGTIAFFSVGFALMFGLSYEGWIGTNHFFLTGLKTGKDFSFFLFQ
VAFMGTAATIVSGAVAERIKFSAYLIVSVVVSLFIYPVFGHWTWGGGWIAKIGFVDFAGSTVVHSLGGWIALAGVIVLGP
RKDKFKEDGTPRKIHGHNLTFSVLGVFILWFGWFGFNGGSALSFTDQVPLIILNTSLAGSVGGIFAITFSWIFYRVASVE
DCMNGVLGGLVAITAGCHAFQPYASLIVGALAGISVVITSWVLEKILKLDDVVGAFPVHGVCGIIGTLLLPILSENQDIR
IYPQFIGVLTCSFWAFGLGMILFLLLKISIGIRVNEEFEEKGLNVTEHGAGSSWIDLIHSLKDLAKGGGDLTRKIHVDSG
TEAGAIAFLMNRYLANLGQMIYTIKEKSIELEYSSSEISVAWGKMSQGIQQQAANLGEVTSIFDSFRESFQTISSSAAQQ
KEMETSASELLNELVFGFQKFDSDLKNSSEKSEESVKAIDLSRKELNQLETDINDIGSSAKKVEGLVKLLNDISTKLGML
SINASIEAARSGAAGKGFGVVAEEISKLASSTQESTKKASEILGEIQSTVSRGKTTVQTSVEFFKNLTEEFRFLAETYIT
IRKSSLHYSNLIGNLNRLNTSITNQSEIIMTDIDKRFSEIGNLYESVDLINGAFHEISAQSEELNATGEFLKQLAEILNS
LVRNFRVEQNSSQELIPG

Sequences:

>Translated_818_residues
MERIYFGIYPTTRNSKKRSPRKTSPIKLRKNESFGNFMKNRVANRIVLILFLGINLPLFSESPALELSKTVDPIWLILCA
ALVFFMQAGFLMLETGLSRLKNTINVAVKNLMDYIVGTIAFFSVGFALMFGLSYEGWIGTNHFFLTGLKTGKDFSFFLFQ
VAFMGTAATIVSGAVAERIKFSAYLIVSVVVSLFIYPVFGHWTWGGGWIAKIGFVDFAGSTVVHSLGGWIALAGVIVLGP
RKDKFKEDGTPRKIHGHNLTFSVLGVFILWFGWFGFNGGSALSFTDQVPLIILNTSLAGSVGGIFAITFSWIFYRVASVE
DCMNGVLGGLVAITAGCHAFQPYASLIVGALAGISVVITSWVLEKILKLDDVVGAFPVHGVCGIIGTLLLPILSENQDIR
IYPQFIGVLTCSFWAFGLGMILFLLLKISIGIRVNEEFEEKGLNVTEHGAGSSWIDLIHSLKDLAKGGGDLTRKIHVDSG
TEAGAIAFLMNRYLANLGQMIYTIKEKSIELEYSSSEISVAWGKMSQGIQQQAANLGEVTSIFDSFRESFQTISSSAAQQ
KEMETSASELLNELVFGFQKFDSDLKNSSEKSEESVKAIDLSRKELNQLETDINDIGSSAKKVEGLVKLLNDISTKLGML
SINASIEAARSGAAGKGFGVVAEEISKLASSTQESTKKASEILGEIQSTVSRGKTTVQTSVEFFKNLTEEFRFLAETYIT
IRKSSLHYSNLIGNLNRLNTSITNQSEIIMTDIDKRFSEIGNLYESVDLINGAFHEISAQSEELNATGEFLKQLAEILNS
LVRNFRVEQNSSQELIPG
>Mature_818_residues
MERIYFGIYPTTRNSKKRSPRKTSPIKLRKNESFGNFMKNRVANRIVLILFLGINLPLFSESPALELSKTVDPIWLILCA
ALVFFMQAGFLMLETGLSRLKNTINVAVKNLMDYIVGTIAFFSVGFALMFGLSYEGWIGTNHFFLTGLKTGKDFSFFLFQ
VAFMGTAATIVSGAVAERIKFSAYLIVSVVVSLFIYPVFGHWTWGGGWIAKIGFVDFAGSTVVHSLGGWIALAGVIVLGP
RKDKFKEDGTPRKIHGHNLTFSVLGVFILWFGWFGFNGGSALSFTDQVPLIILNTSLAGSVGGIFAITFSWIFYRVASVE
DCMNGVLGGLVAITAGCHAFQPYASLIVGALAGISVVITSWVLEKILKLDDVVGAFPVHGVCGIIGTLLLPILSENQDIR
IYPQFIGVLTCSFWAFGLGMILFLLLKISIGIRVNEEFEEKGLNVTEHGAGSSWIDLIHSLKDLAKGGGDLTRKIHVDSG
TEAGAIAFLMNRYLANLGQMIYTIKEKSIELEYSSSEISVAWGKMSQGIQQQAANLGEVTSIFDSFRESFQTISSSAAQQ
KEMETSASELLNELVFGFQKFDSDLKNSSEKSEESVKAIDLSRKELNQLETDINDIGSSAKKVEGLVKLLNDISTKLGML
SINASIEAARSGAAGKGFGVVAEEISKLASSTQESTKKASEILGEIQSTVSRGKTTVQTSVEFFKNLTEEFRFLAETYIT
IRKSSLHYSNLIGNLNRLNTSITNQSEIIMTDIDKRFSEIGNLYESVDLINGAFHEISAQSEELNATGEFLKQLAEILNS
LVRNFRVEQNSSQELIPG

Specific function: Involved In The Uptake Of Ammonia (Probable). [C]

COG id: COG0004

COG function: function code P; Ammonia permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ammonium transporter (TC 2.A.49) family [H]

Homologues:

Organism=Escherichia coli, GI1786656, Length=425, Percent_Identity=32, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI2367378, Length=249, Percent_Identity=28.1124497991968, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI1788195, Length=254, Percent_Identity=25.1968503937008, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787690, Length=339, Percent_Identity=23.8938053097345, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1789453, Length=250, Percent_Identity=21.6, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1788194, Length=269, Percent_Identity=24.5353159851301, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17550180, Length=446, Percent_Identity=34.9775784753363, Blast_Score=226, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI32564042, Length=434, Percent_Identity=31.3364055299539, Blast_Score=199, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17550182, Length=428, Percent_Identity=31.7757009345794, Blast_Score=192, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI133931100, Length=491, Percent_Identity=28.9205702647658, Blast_Score=184, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6325396, Length=445, Percent_Identity=29.2134831460674, Blast_Score=138, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6324187, Length=339, Percent_Identity=28.9085545722714, Blast_Score=133, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321559, Length=418, Percent_Identity=28.9473684210526, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI161078314, Length=455, Percent_Identity=31.8681318681319, Blast_Score=188, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001905
- InterPro:   IPR018047
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00909 Ammonium_transp [H]

EC number: NA

Molecular weight: Translated: 89581; Mature: 89581

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS01219 AMMONIUM_TRANSP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIYFGIYPTTRNSKKRSPRKTSPIKLRKNESFGNFMKNRVANRIVLILFLGINLPLFS
CCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
ESPALELSKTVDPIWLILCAALVFFMQAGFLMLETGLSRLKNTINVAVKNLMDYIVGTIA
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFSVGFALMFGLSYEGWIGTNHFFLTGLKTGKDFSFFLFQVAFMGTAATIVSGAVAERIK
HHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSAYLIVSVVVSLFIYPVFGHWTWGGGWIAKIGFVDFAGSTVVHSLGGWIALAGVIVLGP
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEECC
RKDKFKEDGTPRKIHGHNLTFSVLGVFILWFGWFGFNGGSALSFTDQVPLIILNTSLAGS
CCHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCC
VGGIFAITFSWIFYRVASVEDCMNGVLGGLVAITAGCHAFQPYASLIVGALAGISVVITS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
WVLEKILKLDDVVGAFPVHGVCGIIGTLLLPILSENQDIRIYPQFIGVLTCSFWAFGLGM
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHH
ILFLLLKISIGIRVNEEFEEKGLNVTEHGAGSSWIDLIHSLKDLAKGGGDLTRKIHVDSG
HHHHHHHHHCCCEECCHHHHCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCC
TEAGAIAFLMNRYLANLGQMIYTIKEKSIELEYSSSEISVAWGKMSQGIQQQAANLGEVT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEEHHHHHHHHHHHHHCHHHHH
SIFDSFRESFQTISSSAAQQKEMETSASELLNELVFGFQKFDSDLKNSSEKSEESVKAID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LSRKELNQLETDINDIGSSAKKVEGLVKLLNDISTKLGMLSINASIEAARSGAAGKGFGV
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHCCCCCCCCHH
VAEEISKLASSTQESTKKASEILGEIQSTVSRGKTTVQTSVEFFKNLTEEFRFLAETYIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IRKSSLHYSNLIGNLNRLNTSITNQSEIIMTDIDKRFSEIGNLYESVDLINGAFHEISAQ
HHHCCCHHHHHHCCHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEELNATGEFLKQLAEILNSLVRNFRVEQNSSQELIPG
HHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MERIYFGIYPTTRNSKKRSPRKTSPIKLRKNESFGNFMKNRVANRIVLILFLGINLPLFS
CCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
ESPALELSKTVDPIWLILCAALVFFMQAGFLMLETGLSRLKNTINVAVKNLMDYIVGTIA
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFSVGFALMFGLSYEGWIGTNHFFLTGLKTGKDFSFFLFQVAFMGTAATIVSGAVAERIK
HHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSAYLIVSVVVSLFIYPVFGHWTWGGGWIAKIGFVDFAGSTVVHSLGGWIALAGVIVLGP
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEECC
RKDKFKEDGTPRKIHGHNLTFSVLGVFILWFGWFGFNGGSALSFTDQVPLIILNTSLAGS
CCHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCC
VGGIFAITFSWIFYRVASVEDCMNGVLGGLVAITAGCHAFQPYASLIVGALAGISVVITS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
WVLEKILKLDDVVGAFPVHGVCGIIGTLLLPILSENQDIRIYPQFIGVLTCSFWAFGLGM
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHH
ILFLLLKISIGIRVNEEFEEKGLNVTEHGAGSSWIDLIHSLKDLAKGGGDLTRKIHVDSG
HHHHHHHHHCCCEECCHHHHCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCC
TEAGAIAFLMNRYLANLGQMIYTIKEKSIELEYSSSEISVAWGKMSQGIQQQAANLGEVT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEEHHHHHHHHHHHHHCHHHHH
SIFDSFRESFQTISSSAAQQKEMETSASELLNELVFGFQKFDSDLKNSSEKSEESVKAID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LSRKELNQLETDINDIGSSAKKVEGLVKLLNDISTKLGMLSINASIEAARSGAAGKGFGV
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHCCCCCCCCHH
VAEEISKLASSTQESTKKASEILGEIQSTVSRGKTTVQTSVEFFKNLTEEFRFLAETYIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IRKSSLHYSNLIGNLNRLNTSITNQSEIIMTDIDKRFSEIGNLYESVDLINGAFHEISAQ
HHHCCCHHHHHHCCHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEELNATGEFLKQLAEILNSLVRNFRVEQNSSQELIPG
HHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NH3 [Periplasm] [C]

Specific reaction: NH3 [Periplasm] = NH3 [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]