Click here to switch to the map view.

The map label for this gene is mch [H]

Identifier: 45358754

GI number: 45358754

Start: 1173159

End: 1174130

Strand: Direct

Name: mch [H]

Synonym: MMP1191

Alternate gene names: 45358754

Gene position: 1173159-1174130 (Clockwise)

Preceding gene: 45358750

Following gene: 45358755

Centisome position: 70.62

GC content: 37.76

Gene sequence:

>972_bases
GTGCTTAGTGTAAATTTAGCTTCATTACCAATTGTTGAAGAAATGATCAGCAGAAAAGAAGACTTAAACATTGAAGTAAT
TAAATTAGAAAACGGAGCTACAGTACTTGACTGTGGTGTAAACGTAATGGGAAGCTTTGAAGCAGGTAAATTATTTACAA
AAATCTGTCTTGGTGGACTTGCACACGTTGGAATAAGCATTTCAGGATCCCTCGATAACAAACTCGTTTTACCATGCGTA
AAAATTAAAACATCACACCCTGCAATCGCAACACTCGGTTCACAAAAAGCTGGATGGAGCGTAAGTGTTGGAAAATACTT
CGCAATGGGTTCAGGACCTGCAAGAGCATTAGCAATGATGCCAAAAGCAACCTACGAAGAAATTGACTACAGAGACGAAG
CAGATGTTGCAATTCTTTGTTTAGAATCTTCACAACTTCCAGATGAAAACGTTGCTGACCACGTTGCTGAAAAATGTGGC
GTAGATGTTTCAAAAGTTTATTTACTCGTTGCTCCAACAGCTTCAATGGTAGGAGCAGTTCAAATCAGCGGTAGAGTTGT
AGAAAACGGAACCTACAAAATGTTAGAAGCTCTTCACTTTGATGTAAGAAAAGTTAAATTTGCAGCAGGTATTGCTCCAG
TTGCTCCAGTAATCGGAGACGACTTGAAAATGATGGGTGCTACAAACGACATGGTTTTATACGGCGGTAGAACCTTCTAC
TACGTTAAAAGCGATGAAGGAGACGACATCGAAAACTTATGTAAATCATTACCATCTTGTTCCGCTGAAACTTACGGAAA
ACCATTCTTAGATGTATTCAAAGAAGCAAACTACGATTTCTACAAAATTGATAAAGGAATGTTTGCTCCAGCAATTGTTA
CAATCAACGACCTTAGAACCGGAAAATTAATGTCATACGGTGAAACAAACGTTGATGTAATCAAAAAATCATTAAAATTC
AGCCAATTATAA

Upstream 100 bases:

>100_bases
TTGTAAATTGGCCTTTTTAAGGGCATTTTTTTAAATCAAATCAAAAGTTATAAAAATTAAAAAATGTCTAAAAAACATAG
AATATAAAAAAGGTGGAACA

Downstream 100 bases:

>100_bases
ATTAATATAAATTATAACTATAAATATAAATACTAAATTTTAATATCTATTTTTTAAAATATATTTCGTGTTTTGTCAGA
ATTTACAAAATTAAAATTAC

Product: N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase

Products: NA

Alternate protein names: Methenyl-H4MPT cyclohydrolase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MLSVNLASLPIVEEMISRKEDLNIEVIKLENGATVLDCGVNVMGSFEAGKLFTKICLGGLAHVGISISGSLDNKLVLPCV
KIKTSHPAIATLGSQKAGWSVSVGKYFAMGSGPARALAMMPKATYEEIDYRDEADVAILCLESSQLPDENVADHVAEKCG
VDVSKVYLLVAPTASMVGAVQISGRVVENGTYKMLEALHFDVRKVKFAAGIAPVAPVIGDDLKMMGATNDMVLYGGRTFY
YVKSDEGDDIENLCKSLPSCSAETYGKPFLDVFKEANYDFYKIDKGMFAPAIVTINDLRTGKLMSYGETNVDVIKKSLKF
SQL

Sequences:

>Translated_323_residues
MLSVNLASLPIVEEMISRKEDLNIEVIKLENGATVLDCGVNVMGSFEAGKLFTKICLGGLAHVGISISGSLDNKLVLPCV
KIKTSHPAIATLGSQKAGWSVSVGKYFAMGSGPARALAMMPKATYEEIDYRDEADVAILCLESSQLPDENVADHVAEKCG
VDVSKVYLLVAPTASMVGAVQISGRVVENGTYKMLEALHFDVRKVKFAAGIAPVAPVIGDDLKMMGATNDMVLYGGRTFY
YVKSDEGDDIENLCKSLPSCSAETYGKPFLDVFKEANYDFYKIDKGMFAPAIVTINDLRTGKLMSYGETNVDVIKKSLKF
SQL
>Mature_323_residues
MLSVNLASLPIVEEMISRKEDLNIEVIKLENGATVLDCGVNVMGSFEAGKLFTKICLGGLAHVGISISGSLDNKLVLPCV
KIKTSHPAIATLGSQKAGWSVSVGKYFAMGSGPARALAMMPKATYEEIDYRDEADVAILCLESSQLPDENVADHVAEKCG
VDVSKVYLLVAPTASMVGAVQISGRVVENGTYKMLEALHFDVRKVKFAAGIAPVAPVIGDDLKMMGATNDMVLYGGRTFY
YVKSDEGDDIENLCKSLPSCSAETYGKPFLDVFKEANYDFYKIDKGMFAPAIVTINDLRTGKLMSYGETNVDVIKKSLKF
SQL

Specific function: Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT(+) [H]

COG id: COG3252

COG function: function code H; Methenyltetrahydromethanopterin cyclohydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MCH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003209 [H]

Pfam domain/function: PF02289 MCH [H]

EC number: =3.5.4.27 [H]

Molecular weight: Translated: 34824; Mature: 34824

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVNLASLPIVEEMISRKEDLNIEVIKLENGATVLDCGVNVMGSFEAGKLFTKICLGGL
CEEECCCCCHHHHHHHCCCCCCCEEEEEECCCCEEEECCCCEECCCCHHHHHHHHHHHHH
AHVGISISGSLDNKLVLPCVKIKTSHPAIATLGSQKAGWSVSVGKYFAMGSGPARALAMM
HHCCEEEECCCCCEEEEEEEEEECCCCCEEECCCCCCCCEEECCCEEEECCCHHHHHHHC
PKATYEEIDYRDEADVAILCLESSQLPDENVADHVAEKCGVDVSKVYLLVAPTASMVGAV
CCCHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHHEEEEEECCHHHHEEE
QISGRVVENGTYKMLEALHFDVRKVKFAAGIAPVAPVIGDDLKMMGATNDMVLYGGRTFY
EECCEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHEECCCCCEEEECCEEEE
YVKSDEGDDIENLCKSLPSCSAETYGKPFLDVFKEANYDFYKIDKGMFAPAIVTINDLRT
EEECCCCCCHHHHHHHCCCCCCHHCCCHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCC
GKLMSYGETNVDVIKKSLKFSQL
CCEEECCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLSVNLASLPIVEEMISRKEDLNIEVIKLENGATVLDCGVNVMGSFEAGKLFTKICLGGL
CEEECCCCCHHHHHHHCCCCCCCEEEEEECCCCEEEECCCCEECCCCHHHHHHHHHHHHH
AHVGISISGSLDNKLVLPCVKIKTSHPAIATLGSQKAGWSVSVGKYFAMGSGPARALAMM
HHCCEEEECCCCCEEEEEEEEEECCCCCEEECCCCCCCCEEECCCEEEECCCHHHHHHHC
PKATYEEIDYRDEADVAILCLESSQLPDENVADHVAEKCGVDVSKVYLLVAPTASMVGAV
CCCHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHHEEEEEECCHHHHEEE
QISGRVVENGTYKMLEALHFDVRKVKFAAGIAPVAPVIGDDLKMMGATNDMVLYGGRTFY
EECCEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHEECCCCCEEEECCEEEE
YVKSDEGDDIENLCKSLPSCSAETYGKPFLDVFKEANYDFYKIDKGMFAPAIVTINDLRT
EEECCCCCCHHHHHHHCCCCCCHHCCCHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCC
GKLMSYGETNVDVIKKSLKFSQL
CCEEECCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA