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The map label for this gene is fucA

Identifier: 45358750

GI number: 45358750

Start: 1170696

End: 1171238

Strand: Direct

Name: fucA

Synonym: MMP1187

Alternate gene names: 45358750

Gene position: 1170696-1171238 (Clockwise)

Preceding gene: 45358749

Following gene: 45358754

Centisome position: 70.48

GC content: 30.02

Gene sequence:

>543_bases
ATGGATTTAACTGAATTTATAAAAATATGCCGTTTATTATACGATCGAAAATACGTCGTTGGTTCTGGGGGAAATGTAAG
TATTCGGGATGGAAATTTAATATATATTACGCCAACAGGTTTAAGTTTAGGATTTTTAACAAAAGAAGATATCTGCATTG
CTGATTTAAATGGAAATATCATAAAAGGAAAACCTACTTCAGAATTAAACATGCATTTAAAAATATACCAAAATAAAGAT
TCAATAAATGCTGTAGTTCACACACACTCAATGTACTGCACCGCATTTTCCGCACTTGATAAAAAACTAAAATTAGTAAC
CCCTGAAGCTGAAATGGTTGTTAAAAAAATAGCATACGTTGACTATTTCCCATGCGGAAGTTTAGAACTTGCAGAAAATG
TTTCAGAATGCATTGAAGACTCAATTATCTTAAAAAACCACGGAATTGTTACATTGGGTAAAGATATAACTGAAGCATAC
ATAAAAACCGAAGTTTTAGAAGAAGTTGCACAGTTAAATTATATTATGAACAATTTAAAATAA

Upstream 100 bases:

>100_bases
AATCGAAGTAATTCCAGTTACCCGTCTTGAAGAAATAATTCCTTTAGCATTTGAATTAAATAATTTATAACCTTAATAAT
TCTCTTTTTTTGGTGATTTT

Downstream 100 bases:

>100_bases
AATAAATCTCTATTCTAAAAATTTTAAAAAAAGTTTAAATTTAAAATTTATTTAAATTCATTTTTTTCTAATTAATTTTT
AATAGTTTCAAGTTCACTTA

Product: class II aldolase/adducin family protein

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MDLTEFIKICRLLYDRKYVVGSGGNVSIRDGNLIYITPTGLSLGFLTKEDICIADLNGNIIKGKPTSELNMHLKIYQNKD
SINAVVHTHSMYCTAFSALDKKLKLVTPEAEMVVKKIAYVDYFPCGSLELAENVSECIEDSIILKNHGIVTLGKDITEAY
IKTEVLEEVAQLNYIMNNLK

Sequences:

>Translated_180_residues
MDLTEFIKICRLLYDRKYVVGSGGNVSIRDGNLIYITPTGLSLGFLTKEDICIADLNGNIIKGKPTSELNMHLKIYQNKD
SINAVVHTHSMYCTAFSALDKKLKLVTPEAEMVVKKIAYVDYFPCGSLELAENVSECIEDSIILKNHGIVTLGKDITEAY
IKTEVLEEVAQLNYIMNNLK
>Mature_180_residues
MDLTEFIKICRLLYDRKYVVGSGGNVSIRDGNLIYITPTGLSLGFLTKEDICIADLNGNIIKGKPTSELNMHLKIYQNKD
SINAVVHTHSMYCTAFSALDKKLKLVTPEAEMVVKKIAYVDYFPCGSLELAENVSECIEDSIILKNHGIVTLGKDITEAY
IKTEVLEEVAQLNYIMNNLK

Specific function: Catalyzes the reversible aldol cleavage of L-fuculose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily

Homologues:

Organism=Escherichia coli, GI1789094, Length=184, Percent_Identity=34.7826086956522, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789164, Length=156, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1790642, Length=185, Percent_Identity=26.4864864864865, Blast_Score=74, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FUCA_METMP (Q6LY06)

Other databases:

- EMBL:   BX950229
- RefSeq:   NP_988307.1
- ProteinModelPortal:   Q6LY06
- GeneID:   2762613
- GenomeReviews:   BX950229_GR
- KEGG:   mmp:MMP1187
- NMPDR:   fig|267377.1.peg.1187
- HOGENOM:   HBG541069
- OMA:   EFIKICH
- ProtClustDB:   CLSK876567
- BioCyc:   MMAR267377:MMP1187-MONOMER
- InterPro:   IPR001303
- Gene3D:   G3DSA:3.40.225.10

Pfam domain/function: PF00596 Aldolase_II; SSF53639 Aldolase_II_N

EC number: =4.1.2.17

Molecular weight: Translated: 20111; Mature: 20111

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTEFIKICRLLYDRKYVVGSGGNVSIRDGNLIYITPTGLSLGFLTKEDICIADLNGNI
CCHHHHHHHHHHHHCCCEEEECCCEEEEECCCEEEEEECCCEEECCCCCCEEEEECCCCE
IKGKPTSELNMHLKIYQNKDSINAVVHTHSMYCTAFSALDKKLKLVTPEAEMVVKKIAYV
ECCCCCCCEEEEEEEEECCCCCEEEEEEHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHH
DYFPCGSLELAENVSECIEDSIILKNHGIVTLGKDITEAYIKTEVLEEVAQLNYIMNNLK
CCCCCCCHHHHHHHHHHHHCCEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLTEFIKICRLLYDRKYVVGSGGNVSIRDGNLIYITPTGLSLGFLTKEDICIADLNGNI
CCHHHHHHHHHHHHCCCEEEECCCEEEEECCCEEEEEECCCEEECCCCCCEEEEECCCCE
IKGKPTSELNMHLKIYQNKDSINAVVHTHSMYCTAFSALDKKLKLVTPEAEMVVKKIAYV
ECCCCCCCEEEEEEEEECCCCCEEEEEEHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHH
DYFPCGSLELAENVSECIEDSIILKNHGIVTLGKDITEAYIKTEVLEEVAQLNYIMNNLK
CCCCCCCHHHHHHHHHHHHCCEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA