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The map label for this gene is luxQ [H]

Identifier: 42523313

GI number: 42523313

Start: 1752629

End: 1754791

Strand: Direct

Name: luxQ [H]

Synonym: Bd1828

Alternate gene names: 42523313

Gene position: 1752629-1754791 (Clockwise)

Preceding gene: 42523312

Following gene: 42523320

Centisome position: 46.33

GC content: 50.16

Gene sequence:

>2163_bases
GTGAAGCAGCGACGAACTGCTGAGTGTGTCTATCTAAAAAAGGCTTTGAAATGTTTTGACCCTGGGGTAGAAAATACCGT
GGGTCTAGAAAATCAGGTTAATCCATTCGGGAAATTAGTACACACCAGTCTCATGGTTCAAGCCACGTTAGGCTTCGATT
GGTCCCAAACAGAACTGGGCCCCATAGAAAATTGGGATTTCGGTTTAATCAATTCCTTGCGCATTGTTTTCAGTTGTCCG
GTCGGGATGTACTGCACCTGGGGTCCCCAGCGGCGGGTTTTCTATAATGATGCCTATATTCCAATACTAAAACATCGTCA
TCCGCACGCCTTGGGTTCACCTCTTCATGAGGTTTGGCCCGAAGTGTGGGATCAGGTGCATGCCATTGCCAGCAAAGTGG
AGTCCGGTGGATTCGTGCTGGAATCTGATGTGCAGTTTGATATCGAAGTCGATGGCAAGCCTCAGGGAAACTATTATACC
TACGGGAATTCTCCGCTGTTTAATGCCGAGGGTAAAGTGTCGGGAATGCTGTGTACGATTCTGGACACGACGACGTCGGT
GAAAAGAAATCAAGCCGCGGAAGAGAGTCTGGCCCGCTCCAATCAGGAAGTCCGGGCTGAGCGCAGAAAGTTGCGTTCTA
TTTTGGAGAAGGCCCCCATTGCCATGGCGGTGCTTGACGGGCCGGAGCACCGTTTTTCGATGACGAATGATTCTTACCGG
GATCTTTTTCTGGGGGATTGTGATGTCACCGGACGAAGAGTGAAAGATGTTTTTCCCAAGACTGAAAAAATCGGGTTGAT
TGCGCTGCTTGATGAAGTCTATCGCACCGGAAAAGTCTTTGAAGCTAAAAATTACGAGATTCATGATCGACGTGCCGACG
GGGTTGAGTTCTCAGTCTTTGTCGATGTTGTCTATCAGCCCATTTATGATTTTAACGATGAAATAGAAGGGCTTGTTCTT
GCTGCGAACAACGTCACGGAGCAGGTGATGGCTGAACGGGCTTTGCAGGCGGCAAAAAGCGCCGCCGAAAATGCGAATCA
GGCCAAGTCTGCGTTCCTGGCAAACATGTCCCACGAAATCCGCACTCCTTTAGGGGTCATTCTGGGGTTTGCAGAAATCA
TCGGGACTCAGGATCTTGATGAGTCAGAACGAAAGAATTATTTCGAAATCATTCATCGCAATGGTTTGTCCCTGACGCGT
ATTATTGATGACATTCTGGATCTGTCCAAAATCGAAGCGGGTAAGTTCGAAATCGAAAAGTCACCTGTGAAACTAAAAAA
ACTGCTTCAGGAAGTCCTGACCATGTTCTTTGACCAGGCCTCCAGAAAAAACATTTATCTGAATTACGAGTTGGGCGAGA
TTGCGCCCCTGATTATTCTTTCTGATGTCGTTCGCATCCGTCAGGTTTTGGTGAATCTGATTGGAAATGCGATCAAGTTC
ACAATGAAGGGGTCCGTCAAGGTGTCCTGCCGAGCAGAGCAGGTGACGGCAACACGCAAGAAAATAGTATTCAGCATTGA
AGACACCGGCATTGGCATGACTCAGGAGCAGGCGGAGCGGTTGTTCCAGCCATTCACGCAAGCCGACGCCACCTCCACTC
GCCAGTTTGGCGGCACGGGACTGGGCTTGGCGCTTTCCAGAAATCTGGCCCGAGCTCTTGGGGGAGATGTCAGTATTGTG
CGTTGTGAGCCCCGGCAGGGTTGTACTTTCGAGTTTTCATTCCAGGCCGAGGATGTCAGTGAACTCTCGGTCGCGGGGCA
AGCAGAGAGTGCCGGTGCCGTGGAACAAAAGCCACTGGCCGGTTTCAAGGTTTTGGCCGTTGATGATTCGCGGGACAACC
GTGAACTGATCTCGACTGTGTTGAGCAGTTGGGGCCTGGATGTCACCGAAGCGGAAAGCGGCGAAGAGGCTCTGACTCAA
GCTCTTAAGGAGCATTTTGATCTCGTTTTGATGGATATTCAGATGCCTGGTCTTGATGGTTTTGGGACTCTGGCGGGCCT
TCGCAAGCAGGGGTTCCAGGGGCCGGTCATCGCCTTGACTGCTCATGCGATGAAAGAGGACAAAGACCGCTCTTTTGCGG
CGGGATTCCTGGATCATCTGACGAAACCGATTAATTCAAAAGTCCTTCTTCAGGCAATTCAGTCGCATCTGAAGCATTCG
TAA

Upstream 100 bases:

>100_bases
AAAAAGCGTCGAGAGATTCGACTGCAAAATAAAACCCGATAATTTTCATATTTGTTTTTTAATTTCTACTAAGGCTCATG
TTCGTTGTTGAATTACATTT

Downstream 100 bases:

>100_bases
ATGATTCTATTTGCAAAGAAGTTCGATCCAGCGAAGGGCTTCCTTCGCGTTGGGGCTGGCGGGGGCGTCCTCGGCCTGAT
TGTCGCCCGTCATGACGTCC

Product: sensory transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
MKQRRTAECVYLKKALKCFDPGVENTVGLENQVNPFGKLVHTSLMVQATLGFDWSQTELGPIENWDFGLINSLRIVFSCP
VGMYCTWGPQRRVFYNDAYIPILKHRHPHALGSPLHEVWPEVWDQVHAIASKVESGGFVLESDVQFDIEVDGKPQGNYYT
YGNSPLFNAEGKVSGMLCTILDTTTSVKRNQAAEESLARSNQEVRAERRKLRSILEKAPIAMAVLDGPEHRFSMTNDSYR
DLFLGDCDVTGRRVKDVFPKTEKIGLIALLDEVYRTGKVFEAKNYEIHDRRADGVEFSVFVDVVYQPIYDFNDEIEGLVL
AANNVTEQVMAERALQAAKSAAENANQAKSAFLANMSHEIRTPLGVILGFAEIIGTQDLDESERKNYFEIIHRNGLSLTR
IIDDILDLSKIEAGKFEIEKSPVKLKKLLQEVLTMFFDQASRKNIYLNYELGEIAPLIILSDVVRIRQVLVNLIGNAIKF
TMKGSVKVSCRAEQVTATRKKIVFSIEDTGIGMTQEQAERLFQPFTQADATSTRQFGGTGLGLALSRNLARALGGDVSIV
RCEPRQGCTFEFSFQAEDVSELSVAGQAESAGAVEQKPLAGFKVLAVDDSRDNRELISTVLSSWGLDVTEAESGEEALTQ
ALKEHFDLVLMDIQMPGLDGFGTLAGLRKQGFQGPVIALTAHAMKEDKDRSFAAGFLDHLTKPINSKVLLQAIQSHLKHS

Sequences:

>Translated_720_residues
MKQRRTAECVYLKKALKCFDPGVENTVGLENQVNPFGKLVHTSLMVQATLGFDWSQTELGPIENWDFGLINSLRIVFSCP
VGMYCTWGPQRRVFYNDAYIPILKHRHPHALGSPLHEVWPEVWDQVHAIASKVESGGFVLESDVQFDIEVDGKPQGNYYT
YGNSPLFNAEGKVSGMLCTILDTTTSVKRNQAAEESLARSNQEVRAERRKLRSILEKAPIAMAVLDGPEHRFSMTNDSYR
DLFLGDCDVTGRRVKDVFPKTEKIGLIALLDEVYRTGKVFEAKNYEIHDRRADGVEFSVFVDVVYQPIYDFNDEIEGLVL
AANNVTEQVMAERALQAAKSAAENANQAKSAFLANMSHEIRTPLGVILGFAEIIGTQDLDESERKNYFEIIHRNGLSLTR
IIDDILDLSKIEAGKFEIEKSPVKLKKLLQEVLTMFFDQASRKNIYLNYELGEIAPLIILSDVVRIRQVLVNLIGNAIKF
TMKGSVKVSCRAEQVTATRKKIVFSIEDTGIGMTQEQAERLFQPFTQADATSTRQFGGTGLGLALSRNLARALGGDVSIV
RCEPRQGCTFEFSFQAEDVSELSVAGQAESAGAVEQKPLAGFKVLAVDDSRDNRELISTVLSSWGLDVTEAESGEEALTQ
ALKEHFDLVLMDIQMPGLDGFGTLAGLRKQGFQGPVIALTAHAMKEDKDRSFAAGFLDHLTKPINSKVLLQAIQSHLKHS
>Mature_720_residues
MKQRRTAECVYLKKALKCFDPGVENTVGLENQVNPFGKLVHTSLMVQATLGFDWSQTELGPIENWDFGLINSLRIVFSCP
VGMYCTWGPQRRVFYNDAYIPILKHRHPHALGSPLHEVWPEVWDQVHAIASKVESGGFVLESDVQFDIEVDGKPQGNYYT
YGNSPLFNAEGKVSGMLCTILDTTTSVKRNQAAEESLARSNQEVRAERRKLRSILEKAPIAMAVLDGPEHRFSMTNDSYR
DLFLGDCDVTGRRVKDVFPKTEKIGLIALLDEVYRTGKVFEAKNYEIHDRRADGVEFSVFVDVVYQPIYDFNDEIEGLVL
AANNVTEQVMAERALQAAKSAAENANQAKSAFLANMSHEIRTPLGVILGFAEIIGTQDLDESERKNYFEIIHRNGLSLTR
IIDDILDLSKIEAGKFEIEKSPVKLKKLLQEVLTMFFDQASRKNIYLNYELGEIAPLIILSDVVRIRQVLVNLIGNAIKF
TMKGSVKVSCRAEQVTATRKKIVFSIEDTGIGMTQEQAERLFQPFTQADATSTRQFGGTGLGLALSRNLARALGGDVSIV
RCEPRQGCTFEFSFQAEDVSELSVAGQAESAGAVEQKPLAGFKVLAVDDSRDNRELISTVLSSWGLDVTEAESGEEALTQ
ALKEHFDLVLMDIQMPGLDGFGTLAGLRKQGFQGPVIALTAHAMKEDKDRSFAAGFLDHLTKPINSKVLLQAIQSHLKHS

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=387, Percent_Identity=33.3333333333333, Blast_Score=205, Evalue=7e-54,
Organism=Escherichia coli, GI48994928, Length=412, Percent_Identity=33.252427184466, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1789149, Length=319, Percent_Identity=34.7962382445141, Blast_Score=188, Evalue=1e-48,
Organism=Escherichia coli, GI87081816, Length=384, Percent_Identity=30.9895833333333, Blast_Score=162, Evalue=7e-41,
Organism=Escherichia coli, GI145693157, Length=247, Percent_Identity=35.2226720647773, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1786912, Length=272, Percent_Identity=27.5735294117647, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788393, Length=219, Percent_Identity=28.310502283105, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=29.5154185022026, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1788549, Length=281, Percent_Identity=25.2669039145907, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786783, Length=249, Percent_Identity=26.9076305220884, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787894, Length=252, Percent_Identity=27.3809523809524, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=28.310502283105, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1790437, Length=117, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI87082012, Length=118, Percent_Identity=33.0508474576271, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87082128, Length=214, Percent_Identity=25.2336448598131, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788550, Length=126, Percent_Identity=30.952380952381, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=209, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789809, Length=118, Percent_Identity=30.5084745762712, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=31.3559322033898, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788905, Length=117, Percent_Identity=37.6068376068376, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI1789808, Length=219, Percent_Identity=27.8538812785388, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=201, Percent_Identity=29.8507462686567, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=103, Percent_Identity=36.8932038834951, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79996; Mature: 79996

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRRTAECVYLKKALKCFDPGVENTVGLENQVNPFGKLVHTSLMVQATLGFDWSQTELG
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHEEEEECCCCCCCCCC
PIENWDFGLINSLRIVFSCPVGMYCTWGPQRRVFYNDAYIPILKHRHPHALGSPLHEVWP
CCCCCCCHHHHHEEEEEECCCCCEECCCCCCEEEECCCEEEHHCCCCCCCCCCCHHHHHH
EVWDQVHAIASKVESGGFVLESDVQFDIEVDGKPQGNYYTYGNSPLFNAEGKVSGMLCTI
HHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCCEEEECCCEEECCCCCCCCEEEEE
LDTTTSVKRNQAAEESLARSNQEVRAERRKLRSILEKAPIAMAVLDGPEHRFSMTNDSYR
ECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEECCCCCCC
DLFLGDCDVTGRRVKDVFPKTEKIGLIALLDEVYRTGKVFEAKNYEIHDRRADGVEFSVF
EEEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCEEECCCCEECCCCCCCCEEEHH
VDVVYQPIYDFNDEIEGLVLAANNVTEQVMAERALQAAKSAAENANQAKSAFLANMSHEI
HHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
RTPLGVILGFAEIIGTQDLDESERKNYFEIIHRNGLSLTRIIDDILDLSKIEAGKFEIEK
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECC
SPVKLKKLLQEVLTMFFDQASRKNIYLNYELGEIAPLIILSDVVRIRQVLVNLIGNAIKF
CCHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
TMKGSVKVSCRAEQVTATRKKIVFSIEDTGIGMTQEQAERLFQPFTQADATSTRQFGGTG
EECCCEEEEEEHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCC
LGLALSRNLARALGGDVSIVRCEPRQGCTFEFSFQAEDVSELSVAGQAESAGAVEQKPLA
HHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCC
GFKVLAVDDSRDNRELISTVLSSWGLDVTEAESGEEALTQALKEHFDLVLMDIQMPGLDG
CEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCC
FGTLAGLRKQGFQGPVIALTAHAMKEDKDRSFAAGFLDHLTKPINSKVLLQAIQSHLKHS
HHHHHHHHHCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKQRRTAECVYLKKALKCFDPGVENTVGLENQVNPFGKLVHTSLMVQATLGFDWSQTELG
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHEEEEECCCCCCCCCC
PIENWDFGLINSLRIVFSCPVGMYCTWGPQRRVFYNDAYIPILKHRHPHALGSPLHEVWP
CCCCCCCHHHHHEEEEEECCCCCEECCCCCCEEEECCCEEEHHCCCCCCCCCCCHHHHHH
EVWDQVHAIASKVESGGFVLESDVQFDIEVDGKPQGNYYTYGNSPLFNAEGKVSGMLCTI
HHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCCEEEECCCEEECCCCCCCCEEEEE
LDTTTSVKRNQAAEESLARSNQEVRAERRKLRSILEKAPIAMAVLDGPEHRFSMTNDSYR
ECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEECCCCCCC
DLFLGDCDVTGRRVKDVFPKTEKIGLIALLDEVYRTGKVFEAKNYEIHDRRADGVEFSVF
EEEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCEEECCCCEECCCCCCCCEEEHH
VDVVYQPIYDFNDEIEGLVLAANNVTEQVMAERALQAAKSAAENANQAKSAFLANMSHEI
HHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
RTPLGVILGFAEIIGTQDLDESERKNYFEIIHRNGLSLTRIIDDILDLSKIEAGKFEIEK
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECC
SPVKLKKLLQEVLTMFFDQASRKNIYLNYELGEIAPLIILSDVVRIRQVLVNLIGNAIKF
CCHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
TMKGSVKVSCRAEQVTATRKKIVFSIEDTGIGMTQEQAERLFQPFTQADATSTRQFGGTG
EECCCEEEEEEHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCC
LGLALSRNLARALGGDVSIVRCEPRQGCTFEFSFQAEDVSELSVAGQAESAGAVEQKPLA
HHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCC
GFKVLAVDDSRDNRELISTVLSSWGLDVTEAESGEEALTQALKEHFDLVLMDIQMPGLDG
CEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCC
FGTLAGLRKQGFQGPVIALTAHAMKEDKDRSFAAGFLDHLTKPINSKVLLQAIQSHLKHS
HHHHHHHHHCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]