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The map label for this gene is yciA [C]

Identifier: 42523312

GI number: 42523312

Start: 1752052

End: 1752570

Strand: Direct

Name: yciA [C]

Synonym: Bd1827

Alternate gene names: 42523312

Gene position: 1752052-1752570 (Clockwise)

Preceding gene: 42523311

Following gene: 42523313

Centisome position: 46.31

GC content: 50.1

Gene sequence:

>519_bases
ATGTGGAGACACAGACCTGCGCTTTGTTTTTTAGAAAGGGGCTGCATCTTGGCTGCTTCAAAAACCGTCTCATCATCTCA
AGTGGTAATGACTCAACTAGTACTTCCTTCCCATACCAATTCTTTGGGAAGTGTTTTCGGCGGAACGATCATGTCCTGGA
TCGACATCTGCGCCGCGATCTGCTCACAACGACATTGTAACAAAGAAACCGTCACGGCCAGCATCGACCGACTGGACTTT
GTGGCGCCGGTTTACAAGGGCTGGGTGGTAAATCTGAAGGCCAGCGTGAACTACACCTCCAGAACGTCGATGGAAGTCGG
AGTTCGTGTCGATGCCGAGAATCCAAAAACCGGCGAGACTTTCCATACGGCTTCAGCGTATCTGACTTTTGTGGCATTGG
GCTCTATGGGAAAACCAACAGAAGTTCCGGGCTTGGTGCTGGAGTCTGACGACGACAAACGTCGCTTTGAACAGGCGAAA
AAGCGTCGAGAGATTCGACTGCAAAATAAAACCCGATAA

Upstream 100 bases:

>100_bases
TACAACTCTACCAGGTAGCGGTTTGAACCGTGGCGGTAACTCCGATATTGGTATGGGCGGCATCTAATCTTTATTGATTA
GATTGGTTCTAAGGCGCAGG

Downstream 100 bases:

>100_bases
TTTTCATATTTGTTTTTTAATTTCTACTAAGGCTCATGTTCGTTGTTGAATTACATTTGTGAAGCAGCGACGAACTGCTG
AGTGTGTCTATCTAAAAAAG

Product: Acyl-CoA thioester hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MWRHRPALCFLERGCILAASKTVSSSQVVMTQLVLPSHTNSLGSVFGGTIMSWIDICAAICSQRHCNKETVTASIDRLDF
VAPVYKGWVVNLKASVNYTSRTSMEVGVRVDAENPKTGETFHTASAYLTFVALGSMGKPTEVPGLVLESDDDKRRFEQAK
KRREIRLQNKTR

Sequences:

>Translated_172_residues
MWRHRPALCFLERGCILAASKTVSSSQVVMTQLVLPSHTNSLGSVFGGTIMSWIDICAAICSQRHCNKETVTASIDRLDF
VAPVYKGWVVNLKASVNYTSRTSMEVGVRVDAENPKTGETFHTASAYLTFVALGSMGKPTEVPGLVLESDDDKRRFEQAK
KRREIRLQNKTR
>Mature_172_residues
MWRHRPALCFLERGCILAASKTVSSSQVVMTQLVLPSHTNSLGSVFGGTIMSWIDICAAICSQRHCNKETVTASIDRLDF
VAPVYKGWVVNLKASVNYTSRTSMEVGVRVDAENPKTGETFHTASAYLTFVALGSMGKPTEVPGLVLESDDDKRRFEQAK
KRREIRLQNKTR

Specific function: Unknown

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI32528284, Length=143, Percent_Identity=39.8601398601399, Blast_Score=104, Evalue=4e-23,
Organism=Homo sapiens, GI32528286, Length=143, Percent_Identity=39.8601398601399, Blast_Score=104, Evalue=4e-23,
Organism=Homo sapiens, GI32528282, Length=143, Percent_Identity=39.8601398601399, Blast_Score=104, Evalue=4e-23,
Organism=Homo sapiens, GI75709208, Length=143, Percent_Identity=39.8601398601399, Blast_Score=104, Evalue=5e-23,
Organism=Homo sapiens, GI22165355, Length=147, Percent_Identity=37.4149659863946, Blast_Score=94, Evalue=4e-20,
Organism=Homo sapiens, GI22165400, Length=147, Percent_Identity=37.4149659863946, Blast_Score=94, Evalue=4e-20,
Organism=Homo sapiens, GI18640736, Length=142, Percent_Identity=36.6197183098592, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1787506, Length=131, Percent_Identity=30.5343511450382, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 19109; Mature: 19109

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWRHRPALCFLERGCILAASKTVSSSQVVMTQLVLPSHTNSLGSVFGGTIMSWIDICAAI
CCCCCCCHHEECCCEEEEECCCCCCCHHEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
CSQRHCNKETVTASIDRLDFVAPVYKGWVVNLKASVNYTSRTSMEVGVRVDAENPKTGET
HHHCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCEEEEEEEECCCCCCCCC
FHTASAYLTFVALGSMGKPTEVPGLVLESDDDKRRFEQAKKRREIRLQNKTR
HHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MWRHRPALCFLERGCILAASKTVSSSQVVMTQLVLPSHTNSLGSVFGGTIMSWIDICAAI
CCCCCCCHHEECCCEEEEECCCCCCCHHEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
CSQRHCNKETVTASIDRLDFVAPVYKGWVVNLKASVNYTSRTSMEVGVRVDAENPKTGET
HHHCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCEEEEEEEECCCCCCCCC
FHTASAYLTFVALGSMGKPTEVPGLVLESDDDKRRFEQAKKRREIRLQNKTR
HHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9784136 [H]