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The map label for this gene is katA [H]

Identifier: 42522696

GI number: 42522696

Start: 1094604

End: 1096133

Strand: Direct

Name: katA [H]

Synonym: Bd1154

Alternate gene names: 42522696

Gene position: 1094604-1096133 (Clockwise)

Preceding gene: 42522692

Following gene: 42522697

Centisome position: 28.94

GC content: 51.7

Gene sequence:

>1530_bases
ATGCTTAAGGGGTCGTTCAAAATTCAAGAAAGGATGCATGATATGGCTCAATCAAAGAAGGGTTTGACCACCAGTGCTGG
TGCGCCGGTTTCAGACAATCAGAATTCGTTGACGGTGGGGCCTCGTGGGCCGTTGGTACTTCAGGATGTGGCGCTGATTG
AAAAGCTCGCGCACCAAAACCGCGAGCGGGTGCCGGAAAGAACAGTGCATGCCAAGGGCTCCGGCGCTTTTGGCACGCTG
ACGATCAACGGAGATATTTCCAAATACACCCGCGCAAAGTTCCTTCAGCCGGGAACAAAAACAGATCTGCTGATTCGTTT
TTCAACGGTTGCCGGCGAAAGGGGCGCTGCAGATGCTGAACGCGACGTGCGGGGATTTGCGCTGAAGTTTTACACCGAAG
AAGGCAACTTTGATTTGGTCGGCAACAACACGCCGGTTTTTTTCGTGCGTGATCCTTATAAATTTCCCGACTTCATTCAC
ACACAAAAACGCGATCCGCGCACCAACTTACGAAGCCCCACGGCAATGTGGGACTTCTGGTCACTAAGTCCCGAGTCCTG
CCACCAGGTGACAATTCTATTCTCTGACCGTGGTTTACCGGCGTCATATCGGCACATGCACGGATTTGGTTCGCACACCT
ATTCCCTGATCAATAGCAAGGAGGACCGTCACTGGGTGAAGTTCCACTTCAAAACCCAGCAAGGGATCAAAAATCTGACC
AATGATGAAGGGGCAGAGCTTGTGGGGCGCACGCGCGAAAGCCATCAGGAGGATCTGTACAATTCGATCGAAGAAAAAAG
CTTTCCGAAATGGCGCATGTACGTGCAGATCATGAGCGAAGAGCAGGCCAAGAAAACCTGGTACAATCCCTTTGATCTTA
CCAAAGTGTGGCCGCACGGAGAGTTCCCGATGATTGAGGTGGGCACCATGGAGCTCAACCGCAATCCGACAAACTATTTT
GCTGAAATAGAGCAGGCGGCTTTCAACCCGAACAACATGGTACCGGGTGTTTCCTGGTCGCCGGACAAGATGCTGCAGTC
GCGCACTTTTGCGTATGCTGATGCCCATCGCTATCGCATCGGCACTCACTACGAAATGCTTCCTGTGAACAAACCCAAAG
TGGAAGTGAACCACTATCATCTGGACGGGGCCATGCGCCTGGATGTTCCTGAATACAATCATGCCTATTATGAACCGAAC
TCTTTCGGGGGACCTGCTCAGCAGGAACAGTACCGGGAACCGCCATTGAAGCTGGATGATGCCACCATGGACCGGTTTGA
TCATCATCAGGGCAATGATGATTACCGTCAGGCAGGGGATTTGTTCCGGTTGATGGACGCCGATAAAAAAAGGCAGCTGC
TGGATAATATCGCCGAACACATGAAGCGCGGAAATGTGCCTGAAGAAATCGTACGCCGTCAGATCGAGGTCTTTATGAGG
TGCGATCCTGCTTACGGTAGCGGCTTGGCCGAGCGCATGGGTGTAAAGGTTTATTCAGACAAATATGAAAGTGGCAGTGC
CCATCATTAG

Upstream 100 bases:

>100_bases
TGCAGGCAGGATATTTGTATTTCCACAGCCAGGGAGGACCCGCAGATTTCGTCTGACATAGCTGAAAAATACAACTCACG
GCGGAATATTCTTTGTCCTT

Downstream 100 bases:

>100_bases
GGCGGAGGATGTATGGCGACCTGGGAAGAATATAAAAAGACAATGGTGGTGGAACCGCTGATTTTTGAAGAGGCCCGCAA
CGGCAACTGCGAGGCCTTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MLKGSFKIQERMHDMAQSKKGLTTSAGAPVSDNQNSLTVGPRGPLVLQDVALIEKLAHQNRERVPERTVHAKGSGAFGTL
TINGDISKYTRAKFLQPGTKTDLLIRFSTVAGERGAADAERDVRGFALKFYTEEGNFDLVGNNTPVFFVRDPYKFPDFIH
TQKRDPRTNLRSPTAMWDFWSLSPESCHQVTILFSDRGLPASYRHMHGFGSHTYSLINSKEDRHWVKFHFKTQQGIKNLT
NDEGAELVGRTRESHQEDLYNSIEEKSFPKWRMYVQIMSEEQAKKTWYNPFDLTKVWPHGEFPMIEVGTMELNRNPTNYF
AEIEQAAFNPNNMVPGVSWSPDKMLQSRTFAYADAHRYRIGTHYEMLPVNKPKVEVNHYHLDGAMRLDVPEYNHAYYEPN
SFGGPAQQEQYREPPLKLDDATMDRFDHHQGNDDYRQAGDLFRLMDADKKRQLLDNIAEHMKRGNVPEEIVRRQIEVFMR
CDPAYGSGLAERMGVKVYSDKYESGSAHH

Sequences:

>Translated_509_residues
MLKGSFKIQERMHDMAQSKKGLTTSAGAPVSDNQNSLTVGPRGPLVLQDVALIEKLAHQNRERVPERTVHAKGSGAFGTL
TINGDISKYTRAKFLQPGTKTDLLIRFSTVAGERGAADAERDVRGFALKFYTEEGNFDLVGNNTPVFFVRDPYKFPDFIH
TQKRDPRTNLRSPTAMWDFWSLSPESCHQVTILFSDRGLPASYRHMHGFGSHTYSLINSKEDRHWVKFHFKTQQGIKNLT
NDEGAELVGRTRESHQEDLYNSIEEKSFPKWRMYVQIMSEEQAKKTWYNPFDLTKVWPHGEFPMIEVGTMELNRNPTNYF
AEIEQAAFNPNNMVPGVSWSPDKMLQSRTFAYADAHRYRIGTHYEMLPVNKPKVEVNHYHLDGAMRLDVPEYNHAYYEPN
SFGGPAQQEQYREPPLKLDDATMDRFDHHQGNDDYRQAGDLFRLMDADKKRQLLDNIAEHMKRGNVPEEIVRRQIEVFMR
CDPAYGSGLAERMGVKVYSDKYESGSAHH
>Mature_509_residues
MLKGSFKIQERMHDMAQSKKGLTTSAGAPVSDNQNSLTVGPRGPLVLQDVALIEKLAHQNRERVPERTVHAKGSGAFGTL
TINGDISKYTRAKFLQPGTKTDLLIRFSTVAGERGAADAERDVRGFALKFYTEEGNFDLVGNNTPVFFVRDPYKFPDFIH
TQKRDPRTNLRSPTAMWDFWSLSPESCHQVTILFSDRGLPASYRHMHGFGSHTYSLINSKEDRHWVKFHFKTQQGIKNLT
NDEGAELVGRTRESHQEDLYNSIEEKSFPKWRMYVQIMSEEQAKKTWYNPFDLTKVWPHGEFPMIEVGTMELNRNPTNYF
AEIEQAAFNPNNMVPGVSWSPDKMLQSRTFAYADAHRYRIGTHYEMLPVNKPKVEVNHYHLDGAMRLDVPEYNHAYYEPN
SFGGPAQQEQYREPPLKLDDATMDRFDHHQGNDDYRQAGDLFRLMDADKKRQLLDNIAEHMKRGNVPEEIVRRQIEVFMR
CDPAYGSGLAERMGVKVYSDKYESGSAHH

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=478, Percent_Identity=50, Blast_Score=488, Evalue=1e-138,
Organism=Escherichia coli, GI48994891, Length=518, Percent_Identity=37.6447876447876, Blast_Score=341, Evalue=8e-95,
Organism=Caenorhabditis elegans, GI71998444, Length=470, Percent_Identity=48.2978723404255, Blast_Score=456, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI25151141, Length=488, Percent_Identity=45.9016393442623, Blast_Score=445, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI25147792, Length=480, Percent_Identity=46.25, Blast_Score=444, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6320462, Length=500, Percent_Identity=45.2, Blast_Score=396, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6321525, Length=338, Percent_Identity=47.0414201183432, Blast_Score=320, Evalue=2e-88,
Organism=Drosophila melanogaster, GI17981717, Length=484, Percent_Identity=49.3801652892562, Blast_Score=468, Evalue=1e-132,
Organism=Drosophila melanogaster, GI19920968, Length=488, Percent_Identity=43.2377049180328, Blast_Score=425, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 58535; Mature: 58535

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS00437 CATALASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKGSFKIQERMHDMAQSKKGLTTSAGAPVSDNQNSLTVGPRGPLVLQDVALIEKLAHQN
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
RERVPERTVHAKGSGAFGTLTINGDISKYTRAKFLQPGTKTDLLIRFSTVAGERGAADAE
HHCCCCHHEECCCCCCEEEEEECCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCH
RDVRGFALKFYTEEGNFDLVGNNTPVFFVRDPYKFPDFIHTQKRDPRTNLRSPTAMWDFW
HCCCEEEEEEEECCCCEEEECCCCCEEEEECCCCCCHHHHCCCCCCCCCCCCCCCEEEEE
SLSPESCHQVTILFSDRGLPASYRHMHGFGSHTYSLINSKEDRHWVKFHFKTQQGIKNLT
CCCCCCCCEEEEEEECCCCCHHHHHHCCCCCHHHHHHCCCCCCEEEEEEEEHHHHHHHCC
NDEGAELVGRTRESHQEDLYNSIEEKSFPKWRMYVQIMSEEQAKKTWYNPFDLTKVWPHG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHCCCCCCCEEECCCC
EFPMIEVGTMELNRNPTNYFAEIEQAAFNPNNMVPGVSWSPDKMLQSRTFAYADAHRYRI
CCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHEEECCCEEEE
GTHYEMLPVNKPKVEVNHYHLDGAMRLDVPEYNHAYYEPNSFGGPAQQEQYREPPLKLDD
CCCEEEECCCCCEEEEEEEEECCEEEECCCCCCCCEECCCCCCCCCCHHHHCCCCCCCCC
ATMDRFDHHQGNDDYRQAGDLFRLMDADKKRQLLDNIAEHMKRGNVPEEIVRRQIEVFMR
HHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
CDPAYGSGLAERMGVKVYSDKYESGSAHH
CCCCCCCCHHHHHCCEEEECCCCCCCCCC
>Mature Secondary Structure
MLKGSFKIQERMHDMAQSKKGLTTSAGAPVSDNQNSLTVGPRGPLVLQDVALIEKLAHQN
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
RERVPERTVHAKGSGAFGTLTINGDISKYTRAKFLQPGTKTDLLIRFSTVAGERGAADAE
HHCCCCHHEECCCCCCEEEEEECCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCH
RDVRGFALKFYTEEGNFDLVGNNTPVFFVRDPYKFPDFIHTQKRDPRTNLRSPTAMWDFW
HCCCEEEEEEEECCCCEEEECCCCCEEEEECCCCCCHHHHCCCCCCCCCCCCCCCEEEEE
SLSPESCHQVTILFSDRGLPASYRHMHGFGSHTYSLINSKEDRHWVKFHFKTQQGIKNLT
CCCCCCCCEEEEEEECCCCCHHHHHHCCCCCHHHHHHCCCCCCEEEEEEEEHHHHHHHCC
NDEGAELVGRTRESHQEDLYNSIEEKSFPKWRMYVQIMSEEQAKKTWYNPFDLTKVWPHG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHCCCCCCCEEECCCC
EFPMIEVGTMELNRNPTNYFAEIEQAAFNPNNMVPGVSWSPDKMLQSRTFAYADAHRYRI
CCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHEEECCCEEEE
GTHYEMLPVNKPKVEVNHYHLDGAMRLDVPEYNHAYYEPNSFGGPAQQEQYREPPLKLDD
CCCEEEECCCCCEEEEEEEEECCEEEECCCCCCCCEECCCCCCCCCCHHHHCCCCCCCCC
ATMDRFDHHQGNDDYRQAGDLFRLMDADKKRQLLDNIAEHMKRGNVPEEIVRRQIEVFMR
HHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
CDPAYGSGLAERMGVKVYSDKYESGSAHH
CCCCCCCCHHHHHCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8955300; 11481430 [H]