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The map label for this gene is gapdh [H]

Identifier: 42522605

GI number: 42522605

Start: 994370

End: 995377

Strand: Direct

Name: gapdh [H]

Synonym: Bd1049

Alternate gene names: 42522605

Gene position: 994370-995377 (Clockwise)

Preceding gene: 42522604

Following gene: 42522606

Centisome position: 26.29

GC content: 50.2

Gene sequence:

>1008_bases
ATGTCTAAGTTGCGTGTTGGTATCAACGGTTTTGGTCGTATTGGTCGTGTTCTTTTCCGCGCGGGTTTTGAAAAATTCGA
TATCGTCGGAATCAATTCCCTGGACAGCATCGAAGGTGATGCTCACTTGCTGAAATACGACTCTGCCCATGGCGTTTTCA
ATGCAGACGTTTCCACCGAAGGTCACAACCTGATCGTTAACGGTAAAAAAATCGCCGTTTCCAAAACTCGCAATCCAGCC
GAAGTTCCTTGGAAGGACCTGGGCGTGGACCTTGTTCTTGAGTGCACAGGCGCATTCAAAAAACGTGAAGACTTCATGCA
ACACATCTCTGCTGGTGCGAAACGCGTTTTGGTTTCCGGCCCTGCTGAAAAAGGTGCTGACATCACAATGGTGTACGGTA
TCAACCACGAATCTTACGATCCATCCAAGCACGTTGTTGTTTCCAACGCGTCCTGCACGACAAACTGCCTTGCGCCTTTG
GCGAAAGTTCTGAACGACACCTTCGGTATCGAACACGGTACGATGATGACAGTTCACTCTTACACGAATGACCAAAAGAT
CCTGGACGCTCCTCACAGCGATTTGCGCCGTGCCCGTGCTGCGGCGGTCAGCATGATTCCGACAACAACCGGCGCTGCGA
AAAACGTGGGCCTGGTGTTGCCAGAGCTGAAAGGTCTGATCGACGGTATCTCCGTGCGTGTTCCGACTCCGAACGTTTCT
TTGGTGGATTTCACATTCACTGCGAAAAAAGACGTGACCCGTGAATCTGTGAACGAAGCTTTGATCAAAGCTTCCGAAGG
CGCGATGAAAGGTGTTCTGGCAGTAGAACACAATGAACTGGTCAGCGTTGACTTCAACGGCAACAAACATTCTTCCATCG
TCGATCTGGCTACAACCATGGTTGTGGGCCCTCGCATGGTGAAAGTTCTTTCCTGGTACGACAATGAAACTGGCTTCTCC
AACCGTATGGTGGACGTGGCCCTGCACATGCAGAAGAAAGGTCTTTAA

Upstream 100 bases:

>100_bases
TAATTTTCACTAAAAGCCAGTCTATGACTAACAGTGTCTAGACTGGCTTTTTAGTCTCCAAAAGCCGATATTGAGTGGGT
TTAAAACAAGGAGCTCACTC

Downstream 100 bases:

>100_bases
TTCATGGCTAACGGTCTTAAAGGCATCAAGACAGTTCGTGATTTCGAGTTGGCGGGAAAAGTTGTTTTCCTGCGCTTGGA
TTTGAACGTTCCAATGGAGA

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSKLRVGINGFGRIGRVLFRAGFEKFDIVGINSLDSIEGDAHLLKYDSAHGVFNADVSTEGHNLIVNGKKIAVSKTRNPA
EVPWKDLGVDLVLECTGAFKKREDFMQHISAGAKRVLVSGPAEKGADITMVYGINHESYDPSKHVVVSNASCTTNCLAPL
AKVLNDTFGIEHGTMMTVHSYTNDQKILDAPHSDLRRARAAAVSMIPTTTGAAKNVGLVLPELKGLIDGISVRVPTPNVS
LVDFTFTAKKDVTRESVNEALIKASEGAMKGVLAVEHNELVSVDFNGNKHSSIVDLATTMVVGPRMVKVLSWYDNETGFS
NRMVDVALHMQKKGL

Sequences:

>Translated_335_residues
MSKLRVGINGFGRIGRVLFRAGFEKFDIVGINSLDSIEGDAHLLKYDSAHGVFNADVSTEGHNLIVNGKKIAVSKTRNPA
EVPWKDLGVDLVLECTGAFKKREDFMQHISAGAKRVLVSGPAEKGADITMVYGINHESYDPSKHVVVSNASCTTNCLAPL
AKVLNDTFGIEHGTMMTVHSYTNDQKILDAPHSDLRRARAAAVSMIPTTTGAAKNVGLVLPELKGLIDGISVRVPTPNVS
LVDFTFTAKKDVTRESVNEALIKASEGAMKGVLAVEHNELVSVDFNGNKHSSIVDLATTMVVGPRMVKVLSWYDNETGFS
NRMVDVALHMQKKGL
>Mature_334_residues
SKLRVGINGFGRIGRVLFRAGFEKFDIVGINSLDSIEGDAHLLKYDSAHGVFNADVSTEGHNLIVNGKKIAVSKTRNPAE
VPWKDLGVDLVLECTGAFKKREDFMQHISAGAKRVLVSGPAEKGADITMVYGINHESYDPSKHVVVSNASCTTNCLAPLA
KVLNDTFGIEHGTMMTVHSYTNDQKILDAPHSDLRRARAAAVSMIPTTTGAAKNVGLVLPELKGLIDGISVRVPTPNVSL
VDFTFTAKKDVTRESVNEALIKASEGAMKGVLAVEHNELVSVDFNGNKHSSIVDLATTMVVGPRMVKVLSWYDNETGFSN
RMVDVALHMQKKGL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=338, Percent_Identity=46.1538461538462, Blast_Score=299, Evalue=2e-81,
Organism=Homo sapiens, GI7657116, Length=331, Percent_Identity=44.1087613293051, Blast_Score=283, Evalue=1e-76,
Organism=Escherichia coli, GI1788079, Length=332, Percent_Identity=49.3975903614458, Blast_Score=318, Evalue=4e-88,
Organism=Escherichia coli, GI1789295, Length=332, Percent_Identity=46.9879518072289, Blast_Score=303, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI17534677, Length=344, Percent_Identity=47.093023255814, Blast_Score=302, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI17534679, Length=344, Percent_Identity=46.8023255813954, Blast_Score=301, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI32566163, Length=343, Percent_Identity=46.6472303206997, Blast_Score=296, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI17568413, Length=343, Percent_Identity=46.6472303206997, Blast_Score=295, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6322409, Length=333, Percent_Identity=46.5465465465465, Blast_Score=310, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6322468, Length=333, Percent_Identity=46.2462462462462, Blast_Score=303, Evalue=3e-83,
Organism=Saccharomyces cerevisiae, GI6321631, Length=333, Percent_Identity=46.2462462462462, Blast_Score=302, Evalue=5e-83,
Organism=Drosophila melanogaster, GI19922412, Length=332, Percent_Identity=46.3855421686747, Blast_Score=293, Evalue=1e-79,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=45.6456456456456, Blast_Score=287, Evalue=8e-78,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=45.6456456456456, Blast_Score=287, Evalue=8e-78,
Organism=Drosophila melanogaster, GI17933600, Length=333, Percent_Identity=44.7447447447448, Blast_Score=284, Evalue=5e-77,
Organism=Drosophila melanogaster, GI18110149, Length=333, Percent_Identity=44.7447447447448, Blast_Score=284, Evalue=5e-77,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36183; Mature: 36052

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLRVGINGFGRIGRVLFRAGFEKFDIVGINSLDSIEGDAHLLKYDSAHGVFNADVSTE
CCCEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEECCCCCEEECCCCCC
GHNLIVNGKKIAVSKTRNPAEVPWKDLGVDLVLECTGAFKKREDFMQHISAGAKRVLVSG
CCEEEEECCEEEEECCCCCCCCCHHHCCEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEC
PAEKGADITMVYGINHESYDPSKHVVVSNASCTTNCLAPLAKVLNDTFGIEHGTMMTVHS
CCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEE
YTNDQKILDAPHSDLRRARAAAVSMIPTTTGAAKNVGLVLPELKGLIDGISVRVPTPNVS
CCCCCCEECCCHHHHHHHHHHHHEECCCCCCCCCCCCEECHHHHHHHCCCEEEECCCCCE
LVDFTFTAKKDVTRESVNEALIKASEGAMKGVLAVEHNELVSVDFNGNKHSSIVDLATTM
EEEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCHHHHHHHHH
VVGPRMVKVLSWYDNETGFSNRMVDVALHMQKKGL
HHCHHHHHHHHHCCCCCCCCCCEEEEEEEHHHCCC
>Mature Secondary Structure 
SKLRVGINGFGRIGRVLFRAGFEKFDIVGINSLDSIEGDAHLLKYDSAHGVFNADVSTE
CCEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEECCCCCEEECCCCCC
GHNLIVNGKKIAVSKTRNPAEVPWKDLGVDLVLECTGAFKKREDFMQHISAGAKRVLVSG
CCEEEEECCEEEEECCCCCCCCCHHHCCEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEC
PAEKGADITMVYGINHESYDPSKHVVVSNASCTTNCLAPLAKVLNDTFGIEHGTMMTVHS
CCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEE
YTNDQKILDAPHSDLRRARAAAVSMIPTTTGAAKNVGLVLPELKGLIDGISVRVPTPNVS
CCCCCCEECCCHHHHHHHHHHHHEECCCCCCCCCCCCEECHHHHHHHCCCEEEECCCCCE
LVDFTFTAKKDVTRESVNEALIKASEGAMKGVLAVEHNELVSVDFNGNKHSSIVDLATTM
EEEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCHHHHHHHHH
VVGPRMVKVLSWYDNETGFSNRMVDVALHMQKKGL
HHCHHHHHHHHHCCCCCCCCCCEEEEEEEHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2684782; 2227448; 2656407; 7408868; 193030; 3586018; 9175858 [H]