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The map label for this gene is lysR [H]

Identifier: 42522472

GI number: 42522472

Start: 855256

End: 856155

Strand: Direct

Name: lysR [H]

Synonym: Bd0902

Alternate gene names: 42522472

Gene position: 855256-856155 (Clockwise)

Preceding gene: 42522471

Following gene: 42522473

Centisome position: 22.61

GC content: 51.78

Gene sequence:

>900_bases
GTGCAAAGTGATCAGCTGGATGGTTTGATAGCGCTTAAACTCGTGGCCGAAAGAAGAAACTTCACTGCGGCGGCAACAGA
GCTGGGTGTTTCCGCTTCGGCGGTCAGTCAGGCAATAAAGCAGCTTGAAGGCCGTTTGGGGGTGGCGTTGCTCAGTCGCA
CCACCCGCAGCACCAGTCTGACCGAAGCTGGCGAGCAGTTTTTGGCGCAGGCAGGACCGGCGCTGGATCAGATTCTTTCT
GCTCTGGCCAATGTGGGAACTTATGCGCAAAAGCCTTCGGGGCTTTTGCGCTTGAATATGCCTCGGATGATATATCCTTG
GTTCTTGGCGCCCATCATTGCCAGCTTTCGTAAAAAGTTTCCCGAAGTGGCTGTGGAGTTGTTCTTTGAAGACGCCACTT
CAGATGTAATCGGGCAGGGGTTTGATGCGGGTATCAGATTGTCCGATGTTTTGGCCAAAGACATGGTGGCGATGAAGTTG
GTCGGACCCGTTCGTTTTGTGCCGGTGGCCTCACCGAAGTACTTGAACAAGGCTGGGCGTCCCAAGCATCCCAAGGACTT
GTTGGGTCATGAGTGCATTGTCAGTCGAATTACGCCTGAACGAATTTATGATCGTTGGGAGTTTGAAAACAAAGGAACCG
AATTTCAGGTTCAGGTGAAGCCTGCACTGATATTCAATGACTCAGTTCTGGCTTTGCGTGCCGCCCTTGATGGTTTGGGA
ATTATGTATGCGGCAGAAGAAGCGGTCAGTGACCAGCTGTCGTCTGGAAAGCTGGAGCTGGTGTTGAATCAGTACTCAAC
CACCAGCGCCGGGTTCTATCTTTATTATTCCAAGCGCTCTCAAGTTCTGCCAAAACTAAGAGCTTTCATCGATCACCTGA
AGGCCGAAGGCGTGGTATAG

Upstream 100 bases:

>100_bases
GCAGATCGGTGAGGTGGTGACCATCAATGATCAATATGTGACTCAGACCTGGTGGAAGAAGAACAACAGCGCCAAGGCGG
ATTAACCAAAGGAGTCTTCT

Downstream 100 bases:

>100_bases
CTGCTTACCAGCATCGGTGGTGGCAAGTGGACGGAGCGCCTCCTGCGCTAACACATTCTTCAATGCACTCTTTGATGAAG
TCTCTGACCTTGAGGCTTCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MQSDQLDGLIALKLVAERRNFTAAATELGVSASAVSQAIKQLEGRLGVALLSRTTRSTSLTEAGEQFLAQAGPALDQILS
ALANVGTYAQKPSGLLRLNMPRMIYPWFLAPIIASFRKKFPEVAVELFFEDATSDVIGQGFDAGIRLSDVLAKDMVAMKL
VGPVRFVPVASPKYLNKAGRPKHPKDLLGHECIVSRITPERIYDRWEFENKGTEFQVQVKPALIFNDSVLALRAALDGLG
IMYAAEEAVSDQLSSGKLELVLNQYSTTSAGFYLYYSKRSQVLPKLRAFIDHLKAEGVV

Sequences:

>Translated_299_residues
MQSDQLDGLIALKLVAERRNFTAAATELGVSASAVSQAIKQLEGRLGVALLSRTTRSTSLTEAGEQFLAQAGPALDQILS
ALANVGTYAQKPSGLLRLNMPRMIYPWFLAPIIASFRKKFPEVAVELFFEDATSDVIGQGFDAGIRLSDVLAKDMVAMKL
VGPVRFVPVASPKYLNKAGRPKHPKDLLGHECIVSRITPERIYDRWEFENKGTEFQVQVKPALIFNDSVLALRAALDGLG
IMYAAEEAVSDQLSSGKLELVLNQYSTTSAGFYLYYSKRSQVLPKLRAFIDHLKAEGVV
>Mature_299_residues
MQSDQLDGLIALKLVAERRNFTAAATELGVSASAVSQAIKQLEGRLGVALLSRTTRSTSLTEAGEQFLAQAGPALDQILS
ALANVGTYAQKPSGLLRLNMPRMIYPWFLAPIIASFRKKFPEVAVELFFEDATSDVIGQGFDAGIRLSDVLAKDMVAMKL
VGPVRFVPVASPKYLNKAGRPKHPKDLLGHECIVSRITPERIYDRWEFENKGTEFQVQVKPALIFNDSVLALRAALDGLG
IMYAAEEAVSDQLSSGKLELVLNQYSTTSAGFYLYYSKRSQVLPKLRAFIDHLKAEGVV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787128, Length=281, Percent_Identity=39.1459074733096, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1787589, Length=299, Percent_Identity=34.1137123745819, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1786401, Length=281, Percent_Identity=32.0284697508897, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=31.4878892733564, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789440, Length=276, Percent_Identity=30.0724637681159, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789639, Length=279, Percent_Identity=28.3154121863799, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=31.986531986532, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1788706, Length=294, Percent_Identity=23.8095238095238, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1789173, Length=284, Percent_Identity=27.4647887323944, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786448, Length=272, Percent_Identity=27.5735294117647, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI157672245, Length=150, Percent_Identity=32, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788748, Length=109, Percent_Identity=35.7798165137615, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786508, Length=140, Percent_Identity=30.7142857142857, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790011, Length=260, Percent_Identity=24.2307692307692, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32736; Mature: 32736

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSDQLDGLIALKLVAERRNFTAAATELGVSASAVSQAIKQLEGRLGVALLSRTTRSTSL
CCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
TEAGEQFLAQAGPALDQILSALANVGTYAQKPSGLLRLNMPRMIYPWFLAPIIASFRKKF
HHHHHHHHHHCCHHHHHHHHHHHHCCCHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
PEVAVELFFEDATSDVIGQGFDAGIRLSDVLAKDMVAMKLVGPVRFVPVASPKYLNKAGR
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHCCCC
PKHPKDLLGHECIVSRITPERIYDRWEFENKGTEFQVQVKPALIFNDSVLALRAALDGLG
CCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHCCH
IMYAAEEAVSDQLSSGKLELVLNQYSTTSAGFYLYYSKRSQVLPKLRAFIDHLKAEGVV
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQSDQLDGLIALKLVAERRNFTAAATELGVSASAVSQAIKQLEGRLGVALLSRTTRSTSL
CCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
TEAGEQFLAQAGPALDQILSALANVGTYAQKPSGLLRLNMPRMIYPWFLAPIIASFRKKF
HHHHHHHHHHCCHHHHHHHHHHHHCCCHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
PEVAVELFFEDATSDVIGQGFDAGIRLSDVLAKDMVAMKLVGPVRFVPVASPKYLNKAGR
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHCCCC
PKHPKDLLGHECIVSRITPERIYDRWEFENKGTEFQVQVKPALIFNDSVLALRAALDGLG
CCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHCCH
IMYAAEEAVSDQLSSGKLELVLNQYSTTSAGFYLYYSKRSQVLPKLRAFIDHLKAEGVV
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]