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The map label for this gene is 42522471

Identifier: 42522471

GI number: 42522471

Start: 854167

End: 855240

Strand: Direct

Name: 42522471

Synonym: Bd0901

Alternate gene names: NA

Gene position: 854167-855240 (Clockwise)

Preceding gene: 42522469

Following gene: 42522472

Centisome position: 22.58

GC content: 49.35

Gene sequence:

>1074_bases
ATGGTGGGTTGTTCTTCATTTGGTTCTTTGCCTTCCGACGAGCAAGTGGCGGCTTACCAAAACTCTCTGAACTATGACAA
AGAAAGAAAGGTGTTTGTTAATCGTCGTCCACGTCTGGTGGAAGAAATGCGCAAGCGCACAATGAATTTTGCCACCACCA
AAGAATTCCTGTTCGGTGGGGATGCGGAAAGAATTCCGAGTGAGGCTTTGCCAGAGGTCAGAACTGATTTTGCCAGATTC
AGTCAGGCCGGTGATGACCTGAAGGTCGTCTGGTTTGGTCATTCCAGCGTGCTGATGAAGCTTGATGGCAAGAATGTTTT
GATCGATCCGGTGCTTTCAACATCCACGGGACCCTTCGGTTTTATGATGAAGAGATTCCAAAAGCCGGTGATTGAGCTTT
CTGAATTGCCTGAAATTGATGTGATCATCGTTTCCCATGACCATTGGGATCACTTGGATATGGATTCGATCAAATTCTTT
AAGAACAAGTCCACTCGGTTTGTGGTGCCCCTGGGGGTGGCGGCGCATTTGACCGGATGGGGTATTGAAGCCAGTCGCAT
TCAGGAATTGGACTGGTGGCAGGGGGTGGAAATTGCCGGCATTAAGTTCACGGCAACTCCTGCCCAGCATTTCTCCGGGC
GGGGCTTTACGAATCAGAACAAATCCCTGTGGGCTTCGTGGGTGATCAAAAGTTCCAAGCACAATGTCTATTTCTGTGCG
GACTCTGGCTATGACACGCACTTTAAGGACATAGGTGAAAAGATGGGGCCCTTTGATTTGGCCTTTATTGAAAACGGCCA
GTACAACGAAAAATGGCGTGAGGTGCACCTGTTGCCGGATGAATCCATCCAGGCCTTTAAGGATCTGAATGCGAAAAGGT
ATTTTCCGATTCATTGGGGCATGTTCTCGCTGGCGCTGCATTCCTGGTCTGAACCGATTGAGAAGATTTCTGCAGCCACG
GCCCGTGAGGGAATTTCGTTGGTAGCGCCGCAGATCGGTGAGGTGGTGACCATCAATGATCAATATGTGACTCAGACCTG
GTGGAAGAAGAACAACAGCGCCAAGGCGGATTAA

Upstream 100 bases:

>100_bases
ATTTAGTAGATTCAAGACAAGCTGGAGATTTATGCGTCTTTTAAAAACGGTCCTGATTGTACTGCTGGTTGGTTGTCTGT
TGGGTGTGGGAGGAGTTGCG

Downstream 100 bases:

>100_bases
CCAAAGGAGTCTTCTGTGCAAAGTGATCAGCTGGATGGTTTGATAGCGCTTAAACTCGTGGCCGAAAGAAGAAACTTCAC
TGCGGCGGCAACAGAGCTGG

Product: Zn-dependent hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MVGCSSFGSLPSDEQVAAYQNSLNYDKERKVFVNRRPRLVEEMRKRTMNFATTKEFLFGGDAERIPSEALPEVRTDFARF
SQAGDDLKVVWFGHSSVLMKLDGKNVLIDPVLSTSTGPFGFMMKRFQKPVIELSELPEIDVIIVSHDHWDHLDMDSIKFF
KNKSTRFVVPLGVAAHLTGWGIEASRIQELDWWQGVEIAGIKFTATPAQHFSGRGFTNQNKSLWASWVIKSSKHNVYFCA
DSGYDTHFKDIGEKMGPFDLAFIENGQYNEKWREVHLLPDESIQAFKDLNAKRYFPIHWGMFSLALHSWSEPIEKISAAT
AREGISLVAPQIGEVVTINDQYVTQTWWKKNNSAKAD

Sequences:

>Translated_357_residues
MVGCSSFGSLPSDEQVAAYQNSLNYDKERKVFVNRRPRLVEEMRKRTMNFATTKEFLFGGDAERIPSEALPEVRTDFARF
SQAGDDLKVVWFGHSSVLMKLDGKNVLIDPVLSTSTGPFGFMMKRFQKPVIELSELPEIDVIIVSHDHWDHLDMDSIKFF
KNKSTRFVVPLGVAAHLTGWGIEASRIQELDWWQGVEIAGIKFTATPAQHFSGRGFTNQNKSLWASWVIKSSKHNVYFCA
DSGYDTHFKDIGEKMGPFDLAFIENGQYNEKWREVHLLPDESIQAFKDLNAKRYFPIHWGMFSLALHSWSEPIEKISAAT
AREGISLVAPQIGEVVTINDQYVTQTWWKKNNSAKAD
>Mature_357_residues
MVGCSSFGSLPSDEQVAAYQNSLNYDKERKVFVNRRPRLVEEMRKRTMNFATTKEFLFGGDAERIPSEALPEVRTDFARF
SQAGDDLKVVWFGHSSVLMKLDGKNVLIDPVLSTSTGPFGFMMKRFQKPVIELSELPEIDVIIVSHDHWDHLDMDSIKFF
KNKSTRFVVPLGVAAHLTGWGIEASRIQELDWWQGVEIAGIKFTATPAQHFSGRGFTNQNKSLWASWVIKSSKHNVYFCA
DSGYDTHFKDIGEKMGPFDLAFIENGQYNEKWREVHLLPDESIQAFKDLNAKRYFPIHWGMFSLALHSWSEPIEKISAAT
AREGISLVAPQIGEVVTINDQYVTQTWWKKNNSAKAD

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=249, Percent_Identity=36.144578313253, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI170932481, Length=249, Percent_Identity=36.144578313253, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17543102, Length=275, Percent_Identity=34.9090909090909, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17543100, Length=275, Percent_Identity=34.9090909090909, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI25148824, Length=275, Percent_Identity=34.9090909090909, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17543104, Length=273, Percent_Identity=35.1648351648352, Blast_Score=160, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6325154, Length=263, Percent_Identity=31.9391634980989, Blast_Score=134, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 40664; Mature: 40664

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGCSSFGSLPSDEQVAAYQNSLNYDKERKVFVNRRPRLVEEMRKRTMNFATTKEFLFGG
CCCCCCCCCCCCCCHHHHHHHHCCCCCCHHEEECCCCHHHHHHHHHHCCHHHHHHHHCCC
DAERIPSEALPEVRTDFARFSQAGDDLKVVWFGHSSVLMKLDGKNVLIDPVLSTSTGPFG
CHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCEEEEECCCCCCCCCHH
FMMKRFQKPVIELSELPEIDVIIVSHDHWDHLDMDSIKFFKNKSTRFVVPLGVAAHLTGW
HHHHHHHCHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHCCCCEEEEEECHHHHHCCC
GIEASRIQELDWWQGVEIAGIKFTATPAQHFSGRGFTNQNKSLWASWVIKSSKHNVYFCA
CCCHHHHHHCCCCCCCEEEEEEEECCCHHHCCCCCCCCCCHHEEEEEEEECCCCCEEEEE
DSGYDTHFKDIGEKMGPFDLAFIENGQYNEKWREVHLLPDESIQAFKDLNAKRYFPIHWG
CCCCCCHHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCHHHHHHHCCCCCEEEEEEHH
MFSLALHSWSEPIEKISAATAREGISLVAPQIGEVVTINDQYVTQTWWKKNNSAKAD
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCEEEHHHHCCCCCCCCC
>Mature Secondary Structure
MVGCSSFGSLPSDEQVAAYQNSLNYDKERKVFVNRRPRLVEEMRKRTMNFATTKEFLFGG
CCCCCCCCCCCCCCHHHHHHHHCCCCCCHHEEECCCCHHHHHHHHHHCCHHHHHHHHCCC
DAERIPSEALPEVRTDFARFSQAGDDLKVVWFGHSSVLMKLDGKNVLIDPVLSTSTGPFG
CHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCEEEEECCCCCCCCCHH
FMMKRFQKPVIELSELPEIDVIIVSHDHWDHLDMDSIKFFKNKSTRFVVPLGVAAHLTGW
HHHHHHHCHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHCCCCEEEEEECHHHHHCCC
GIEASRIQELDWWQGVEIAGIKFTATPAQHFSGRGFTNQNKSLWASWVIKSSKHNVYFCA
CCCHHHHHHCCCCCCCEEEEEEEECCCHHHCCCCCCCCCCHHEEEEEEEECCCCCEEEEE
DSGYDTHFKDIGEKMGPFDLAFIENGQYNEKWREVHLLPDESIQAFKDLNAKRYFPIHWG
CCCCCCHHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCHHHHHHHCCCCCEEEEEEHH
MFSLALHSWSEPIEKISAATAREGISLVAPQIGEVVTINDQYVTQTWWKKNNSAKAD
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCEEEHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]