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The map label for this gene is torS [H]

Identifier: 42522105

GI number: 42522105

Start: 465422

End: 467722

Strand: Direct

Name: torS [H]

Synonym: Bd0499

Alternate gene names: 42522105

Gene position: 465422-467722 (Clockwise)

Preceding gene: 42522104

Following gene: 42522106

Centisome position: 12.3

GC content: 53.85

Gene sequence:

>2301_bases
ATGAAAAAGAAGCTGACCTTTGTCCATTTATTCCTGCTGAATCAGCTGGTGACAACCCTGGTGCTTTTGACAGTGCTGGG
GGTGTATGGCACGCATCTTTTCATTCAAGAGCAGCGTGCGATCCGCGAGCGTATGGAACCGGCCTCGGCCCGTGAAGTGG
ACCGGATCAACAATGACTTTGCCACGCTGGAAGCCAACGTTCAGCGCCTTAAGAGCATGGTGGAACTTTTTGATGTGATG
CCCAAGGGCACGCGGGTGGAAAAGTTCCGTCAGTTTGCCTCGGCCACCATTGCGGGCCACAGCACACAATTCAACGCCTG
GGTTGCTTTGGGGCCCCGCCTTGCCAAGGAATACTTGGGACGGGAATCCTATGTGTATGTTGTGCACCGGGATTATTCCC
TGTTTGCCAGTCCCAAATACAATGATCCAACCACTTTCGTTGCAGAAGTGTTTACTGAGCCCGGTTACGACAAGGATCCG
GATGTTCAATGGTGGTGGATGAATGAAAAGAGCTCCGGAGTAAACTATTCGGATTTCTATTTCGACAAGGGCTATATGGA
AAAGGTGATGTTCAGCACCACCACCGGCATTTTCAGCAATGCCGGAAAGCTCGAAGCGGTGGTGGGGATCGACACGTTGG
CCGGGGATATTGCGCATCGACTGGGGATCTTCAAGCTGGGGGATACCGGGGGGGCTCTGGTCGTGGATGAGCACGGTCGC
CCGGTCCTGCCGTTGATCGCCAAAGACACACCCGTGCTGGGTTTTAAATATCTGCGGGCCCTGAATCAGGATGAGTTCAG
GGCGATGCCCAAGCTTTCGCAGAAGGTGTTTAACATTCAAAACCAGCGTCAGCTTCAGGAATTTCCCGGAGCCGACGGCA
AAACTTATCTGACTTATTCCCGTCCCATCAAAGGCAAGCCCTGGCATCTGGTGATTTATCAGGAAAAGGGCGAGGCGTAT
TCCGGATTGTACTTCCGTTTGTTCTTCTTTGGTTTTGTGGCCCTGGTGGCTTATGTGGTGTTCACCCTGATGGTGTGGAT
GACCGGAAAGTACGTGATCGCGCAGGACAAAGAGGCCCTGGCCCGCCTGCAGGATTCCCGCGACCGTGCTGAAGCGGCGA
CGCGGGCCAAGTCATTGTTTCTTTCAACCATGAGCCACGAGATCCGCACGCCACTGAATGCGATGCTGGGATCGGCTGAG
CTGCTGAATGAAACGCATTTGAATTTTGAACAGAAAGAACTTCTGATATCTCTGCAAAGTGCCGGGGATACGCTGCTTAG
CATGCTGAATAACATCCTGGATTTCTCCAAGTTCGAGTCAGGCCGCATGCAGCTGGAAAGCCGTGAGTTTCTGTTGAGCG
ATCTTGTGCGTGAGGTGCAGGCATTGATCAGCACGTCGGTCTTGCGCAAGAATTTGCAGTTCACCTTCCATCCTCCGGAG
CATGACCGCTGGATTGTCGGGGACTCTCTGCGGCTGAAGCAGGTGTTGATGAACCTGCTGGGGAATGCCGTGAAGTTCAC
GGACCGCGGGGCGATCGAGTTGACGGTGCAGCCTTATCCCGGAAGTGAGCCGGGAAAAGAGACTATCTTTTTTGAGGTCA
AGGACACCGGCATCGGGATTGCCAAAGAAAACCTGAAAAAAGTCTTTGATGAATTCGGGCAGGAGGACTCTTCGGTCACG
CGTCGCTTCGGGGGCACGGGCCTGGGCCTGAGCATTTCGCAGAAGATCGTGCAATTGATGGGCGGGGAGCTTTACTGTGA
AAGCCGCCAGTTTGTGGGGTCGCGTTTCCATTTCTCTGTTCAGATGACTTCCCGCCGGGCGGAACTGTGGAGTGCGCGCT
TTAATCTGGAGCTGACGCCGCCGCCGCAGCTGGTGCGACCTAGTTCTGAAGCGGGTCGCAAGAGCATCCTGATCGTGGAT
GACATGGAAGAAAACCACACGCTGCTCAAAGCCTATATCAAGCGTCTGGAATATGTGACCACCGATTCGGCCTACAACGG
CTATGAATGTCTGGAGATGTGGGAACGGGGTCATTACGACATGATCTTTATGGATGTGCAGATGCCGAAGATGTCGGGGC
TGGACACCATCAGGAAGCTGCGTGAAATAGAGCGGGCCCGGGGTCTGCACCGAACCCCGGTGGTGGTGATTTCCGCCAAC
AGCTTTACGGAAGACATTGAAAAAAGCCTTATGGCCGGAGCGGATCAGCACTGTGGCAAGCCGGTGCGCAAACAGACCGT
TCTGGAAATCGTTCAAAAATACTGTTCAGAAGACATCGAAACAGCCCCTGCAAACTCTTAA

Upstream 100 bases:

>100_bases
GAACTATTATTATGAAAAGAACTCTGACGGCTCGGGTGCGAAACTGACCACCTTCTATGGCACTGTCGGGTTGGGTGTGA
ACTTCTAACCCACGGGTAGA

Downstream 100 bases:

>100_bases
GACAGCGTTAAGTTTCTAACAGCTTATCCCGATATTACGAAGGTCCGACCGCGGAACGGATCTTGCCTCTATTCATTATG
AAACGGGCAAACAGGGGGAA

Product: sensory transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 766; Mature: 766

Protein sequence:

>766_residues
MKKKLTFVHLFLLNQLVTTLVLLTVLGVYGTHLFIQEQRAIRERMEPASAREVDRINNDFATLEANVQRLKSMVELFDVM
PKGTRVEKFRQFASATIAGHSTQFNAWVALGPRLAKEYLGRESYVYVVHRDYSLFASPKYNDPTTFVAEVFTEPGYDKDP
DVQWWWMNEKSSGVNYSDFYFDKGYMEKVMFSTTTGIFSNAGKLEAVVGIDTLAGDIAHRLGIFKLGDTGGALVVDEHGR
PVLPLIAKDTPVLGFKYLRALNQDEFRAMPKLSQKVFNIQNQRQLQEFPGADGKTYLTYSRPIKGKPWHLVIYQEKGEAY
SGLYFRLFFFGFVALVAYVVFTLMVWMTGKYVIAQDKEALARLQDSRDRAEAATRAKSLFLSTMSHEIRTPLNAMLGSAE
LLNETHLNFEQKELLISLQSAGDTLLSMLNNILDFSKFESGRMQLESREFLLSDLVREVQALISTSVLRKNLQFTFHPPE
HDRWIVGDSLRLKQVLMNLLGNAVKFTDRGAIELTVQPYPGSEPGKETIFFEVKDTGIGIAKENLKKVFDEFGQEDSSVT
RRFGGTGLGLSISQKIVQLMGGELYCESRQFVGSRFHFSVQMTSRRAELWSARFNLELTPPPQLVRPSSEAGRKSILIVD
DMEENHTLLKAYIKRLEYVTTDSAYNGYECLEMWERGHYDMIFMDVQMPKMSGLDTIRKLREIERARGLHRTPVVVISAN
SFTEDIEKSLMAGADQHCGKPVRKQTVLEIVQKYCSEDIETAPANS

Sequences:

>Translated_766_residues
MKKKLTFVHLFLLNQLVTTLVLLTVLGVYGTHLFIQEQRAIRERMEPASAREVDRINNDFATLEANVQRLKSMVELFDVM
PKGTRVEKFRQFASATIAGHSTQFNAWVALGPRLAKEYLGRESYVYVVHRDYSLFASPKYNDPTTFVAEVFTEPGYDKDP
DVQWWWMNEKSSGVNYSDFYFDKGYMEKVMFSTTTGIFSNAGKLEAVVGIDTLAGDIAHRLGIFKLGDTGGALVVDEHGR
PVLPLIAKDTPVLGFKYLRALNQDEFRAMPKLSQKVFNIQNQRQLQEFPGADGKTYLTYSRPIKGKPWHLVIYQEKGEAY
SGLYFRLFFFGFVALVAYVVFTLMVWMTGKYVIAQDKEALARLQDSRDRAEAATRAKSLFLSTMSHEIRTPLNAMLGSAE
LLNETHLNFEQKELLISLQSAGDTLLSMLNNILDFSKFESGRMQLESREFLLSDLVREVQALISTSVLRKNLQFTFHPPE
HDRWIVGDSLRLKQVLMNLLGNAVKFTDRGAIELTVQPYPGSEPGKETIFFEVKDTGIGIAKENLKKVFDEFGQEDSSVT
RRFGGTGLGLSISQKIVQLMGGELYCESRQFVGSRFHFSVQMTSRRAELWSARFNLELTPPPQLVRPSSEAGRKSILIVD
DMEENHTLLKAYIKRLEYVTTDSAYNGYECLEMWERGHYDMIFMDVQMPKMSGLDTIRKLREIERARGLHRTPVVVISAN
SFTEDIEKSLMAGADQHCGKPVRKQTVLEIVQKYCSEDIETAPANS
>Mature_766_residues
MKKKLTFVHLFLLNQLVTTLVLLTVLGVYGTHLFIQEQRAIRERMEPASAREVDRINNDFATLEANVQRLKSMVELFDVM
PKGTRVEKFRQFASATIAGHSTQFNAWVALGPRLAKEYLGRESYVYVVHRDYSLFASPKYNDPTTFVAEVFTEPGYDKDP
DVQWWWMNEKSSGVNYSDFYFDKGYMEKVMFSTTTGIFSNAGKLEAVVGIDTLAGDIAHRLGIFKLGDTGGALVVDEHGR
PVLPLIAKDTPVLGFKYLRALNQDEFRAMPKLSQKVFNIQNQRQLQEFPGADGKTYLTYSRPIKGKPWHLVIYQEKGEAY
SGLYFRLFFFGFVALVAYVVFTLMVWMTGKYVIAQDKEALARLQDSRDRAEAATRAKSLFLSTMSHEIRTPLNAMLGSAE
LLNETHLNFEQKELLISLQSAGDTLLSMLNNILDFSKFESGRMQLESREFLLSDLVREVQALISTSVLRKNLQFTFHPPE
HDRWIVGDSLRLKQVLMNLLGNAVKFTDRGAIELTVQPYPGSEPGKETIFFEVKDTGIGIAKENLKKVFDEFGQEDSSVT
RRFGGTGLGLSISQKIVQLMGGELYCESRQFVGSRFHFSVQMTSRRAELWSARFNLELTPPPQLVRPSSEAGRKSILIVD
DMEENHTLLKAYIKRLEYVTTDSAYNGYECLEMWERGHYDMIFMDVQMPKMSGLDTIRKLREIERARGLHRTPVVVISAN
SFTEDIEKSLMAGADQHCGKPVRKQTVLEIVQKYCSEDIETAPANS

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=393, Percent_Identity=32.0610687022901, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1789149, Length=327, Percent_Identity=34.8623853211009, Blast_Score=184, Evalue=3e-47,
Organism=Escherichia coli, GI1788713, Length=420, Percent_Identity=32.6190476190476, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=36.9294605809129, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI87081816, Length=361, Percent_Identity=31.5789473684211, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1788549, Length=253, Percent_Identity=28.4584980237154, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=29.8245614035088, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788393, Length=214, Percent_Identity=27.5700934579439, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1786912, Length=265, Percent_Identity=27.1698113207547, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1787894, Length=236, Percent_Identity=26.6949152542373, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1790551, Length=229, Percent_Identity=27.9475982532751, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=28.8135593220339, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790346, Length=242, Percent_Identity=29.7520661157025, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=26.7241379310345, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI87082128, Length=305, Percent_Identity=26.5573770491803, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=233, Percent_Identity=25.3218884120172, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=214, Percent_Identity=25.2336448598131, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1788545, Length=256, Percent_Identity=25.78125, Blast_Score=63, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=83, Percent_Identity=40.9638554216867, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 87101; Mature: 87101

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKLTFVHLFLLNQLVTTLVLLTVLGVYGTHLFIQEQRAIRERMEPASAREVDRINNDF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCHHHHHHHCCCH
ATLEANVQRLKSMVELFDVMPKGTRVEKFRQFASATIAGHSTQFNAWVALGPRLAKEYLG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHCC
RESYVYVVHRDYSLFASPKYNDPTTFVAEVFTEPGYDKDPDVQWWWMNEKSSGVNYSDFY
CCCEEEEEEECCEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHEE
FDKGYMEKVMFSTTTGIFSNAGKLEAVVGIDTLAGDIAHRLGIFKLGDTGGALVVDEHGR
CCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCEEEECCCCCEEEECCCCC
PVLPLIAKDTPVLGFKYLRALNQDEFRAMPKLSQKVFNIQNQRQLQEFPGADGKTYLTYS
CEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEC
RPIKGKPWHLVIYQEKGEAYSGLYFRLFFFGFVALVAYVVFTLMVWMTGKYVIAQDKEAL
CCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHH
ARLQDSRDRAEAATRAKSLFLSTMSHEIRTPLNAMLGSAELLNETHLNFEQKELLISLQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHCCCCCHHHHHHHHHH
AGDTLLSMLNNILDFSKFESGRMQLESREFLLSDLVREVQALISTSVLRKNLQFTFHPPE
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
HDRWIVGDSLRLKQVLMNLLGNAVKFTDRGAIELTVQPYPGSEPGKETIFFEVKDTGIGI
CCCEEECCCHHHHHHHHHHHCCCEEECCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCH
AKENLKKVFDEFGQEDSSVTRRFGGTGLGLSISQKIVQLMGGELYCESRQFVGSRFHFSV
HHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEECCHHHCCCEEEEEE
QMTSRRAELWSARFNLELTPPPQLVRPSSEAGRKSILIVDDMEENHTLLKAYIKRLEYVT
EEHHHHHHHHHHEEEEEECCCCHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHEE
TDSAYNGYECLEMWERGHYDMIFMDVQMPKMSGLDTIRKLREIERARGLHRTPVVVISAN
CCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECC
SFTEDIEKSLMAGADQHCGKPVRKQTVLEIVQKYCSEDIETAPANS
CHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKKKLTFVHLFLLNQLVTTLVLLTVLGVYGTHLFIQEQRAIRERMEPASAREVDRINNDF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCHHHHHHHCCCH
ATLEANVQRLKSMVELFDVMPKGTRVEKFRQFASATIAGHSTQFNAWVALGPRLAKEYLG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHCC
RESYVYVVHRDYSLFASPKYNDPTTFVAEVFTEPGYDKDPDVQWWWMNEKSSGVNYSDFY
CCCEEEEEEECCEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHEE
FDKGYMEKVMFSTTTGIFSNAGKLEAVVGIDTLAGDIAHRLGIFKLGDTGGALVVDEHGR
CCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCEEEECCCCCEEEECCCCC
PVLPLIAKDTPVLGFKYLRALNQDEFRAMPKLSQKVFNIQNQRQLQEFPGADGKTYLTYS
CEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEC
RPIKGKPWHLVIYQEKGEAYSGLYFRLFFFGFVALVAYVVFTLMVWMTGKYVIAQDKEAL
CCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHH
ARLQDSRDRAEAATRAKSLFLSTMSHEIRTPLNAMLGSAELLNETHLNFEQKELLISLQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHCCCCCHHHHHHHHHH
AGDTLLSMLNNILDFSKFESGRMQLESREFLLSDLVREVQALISTSVLRKNLQFTFHPPE
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
HDRWIVGDSLRLKQVLMNLLGNAVKFTDRGAIELTVQPYPGSEPGKETIFFEVKDTGIGI
CCCEEECCCHHHHHHHHHHHCCCEEECCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCH
AKENLKKVFDEFGQEDSSVTRRFGGTGLGLSISQKIVQLMGGELYCESRQFVGSRFHFSV
HHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEECCHHHCCCEEEEEE
QMTSRRAELWSARFNLELTPPPQLVRPSSEAGRKSILIVDDMEENHTLLKAYIKRLEYVT
EEHHHHHHHHHHEEEEEECCCCHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHEE
TDSAYNGYECLEMWERGHYDMIFMDVQMPKMSGLDTIRKLREIERARGLHRTPVVVISAN
CCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECC
SFTEDIEKSLMAGADQHCGKPVRKQTVLEIVQKYCSEDIETAPANS
CHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]