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The map label for this gene is asd [H]

Identifier: 42522092

GI number: 42522092

Start: 453100

End: 454080

Strand: Direct

Name: asd [H]

Synonym: Bd0484

Alternate gene names: 42522092

Gene position: 453100-454080 (Clockwise)

Preceding gene: 42522091

Following gene: 42522093

Centisome position: 11.98

GC content: 51.58

Gene sequence:

>981_bases
GTGGGCGCGACCGGAATGGTCGGCCAAACCTTCATGAACATCCTGTCAGAGCGCAGTTTCCCAATTGAAGAACTGCGCCC
CTTTGCTTCTGAAAACTCTCTGGGTAAGAAAATTGAACTGCAAGGTCAGCAATGGCCTTGTCAGGTATTGAAGGACGGCT
GCTTTGACGGGCTGGATCTGGTTTTCTTCTCGTCCGGAGACGACATCTCGGCTGAATGGGCCCCAAAGGCCGTGGCGGCA
GGGGCTTTTGCCGTAGACAACTCGGCAGCCTTCCGTATGGATCCCAACACCGTGTTGATCGTTCCTGAAGTGAACGGGGA
CCTGGTGAACAAGGATTCCAAACCTCAGATCATCGCCAATCCAAATTGTTCCACCATTCAGTTGGTGGTGGCGTTGAAAC
CTCTGCTTGAAAAATTCGGCCTGGAAGAAGTGCGTGTCAGCACCTACCAGGCGGTGAGTGGAGCCGGTCAGGGCGGTCAT
GACGAATTGATCGAACAGACCACGAATCATCCAAAACCAACAGACCCAAAAACTTTCCCGCACACCATTTTGTTCAACTG
CATTCCTCAGATTGGTTCTTTCAACGATGAAGGTTACTGCAGCGAAGAAGTGAAGATCATGAAAGAGACCCGCAAGATTT
TGGGTCAAAAAGATCTTAAGGTGTCCGCATTCACCGTGCGTATCCCGGCTTTGAACGCTCACAGCGAATCGGTATGGGTG
ACTTTAAACAAGTCCGTCAGTCGTGACGAAGTCATGGCGGCTTTGTCCGGGCAAGAAGGCATCGTAGTTCAGGATGAACC
CAAGAAAAGCGTTTATCCTTTGGCCCGCGATGTTTCTGGCAAGGACCCGGTCTATGTGGGCCGTGTTCACCGTGACCCGG
AAAATCCAAAGATGTGGCTGATGTGGGTTGTTTCAGACAACATCCGCAAAGGGGCTGCCCTGAACGGCATCCAGATCGCG
GAAAAGATCTTCTTTAACTAA

Upstream 100 bases:

>100_bases
AGCGTGTACGCTCCTGCATCTGTGCATGAAAGCGATCTGGTCCTCGAAGACGAGGAAGAAGAGGCGAAGAAAGATGAAAA
GAAAACTTAAAGTCGGTGTG

Downstream 100 bases:

>100_bases
GTGTGGAAAGGGCTGTCTCAGGACGGCCCTTTTTATTTCGACCTTGGTCGGGGCGGGGGGCATTTTTTGACTTCCGGACC
TTAGCATGGTTCGATGAAAG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MGATGMVGQTFMNILSERSFPIEELRPFASENSLGKKIELQGQQWPCQVLKDGCFDGLDLVFFSSGDDISAEWAPKAVAA
GAFAVDNSAAFRMDPNTVLIVPEVNGDLVNKDSKPQIIANPNCSTIQLVVALKPLLEKFGLEEVRVSTYQAVSGAGQGGH
DELIEQTTNHPKPTDPKTFPHTILFNCIPQIGSFNDEGYCSEEVKIMKETRKILGQKDLKVSAFTVRIPALNAHSESVWV
TLNKSVSRDEVMAALSGQEGIVVQDEPKKSVYPLARDVSGKDPVYVGRVHRDPENPKMWLMWVVSDNIRKGAALNGIQIA
EKIFFN

Sequences:

>Translated_326_residues
MGATGMVGQTFMNILSERSFPIEELRPFASENSLGKKIELQGQQWPCQVLKDGCFDGLDLVFFSSGDDISAEWAPKAVAA
GAFAVDNSAAFRMDPNTVLIVPEVNGDLVNKDSKPQIIANPNCSTIQLVVALKPLLEKFGLEEVRVSTYQAVSGAGQGGH
DELIEQTTNHPKPTDPKTFPHTILFNCIPQIGSFNDEGYCSEEVKIMKETRKILGQKDLKVSAFTVRIPALNAHSESVWV
TLNKSVSRDEVMAALSGQEGIVVQDEPKKSVYPLARDVSGKDPVYVGRVHRDPENPKMWLMWVVSDNIRKGAALNGIQIA
EKIFFN
>Mature_325_residues
GATGMVGQTFMNILSERSFPIEELRPFASENSLGKKIELQGQQWPCQVLKDGCFDGLDLVFFSSGDDISAEWAPKAVAAG
AFAVDNSAAFRMDPNTVLIVPEVNGDLVNKDSKPQIIANPNCSTIQLVVALKPLLEKFGLEEVRVSTYQAVSGAGQGGHD
ELIEQTTNHPKPTDPKTFPHTILFNCIPQIGSFNDEGYCSEEVKIMKETRKILGQKDLKVSAFTVRIPALNAHSESVWVT
LNKSVSRDEVMAALSGQEGIVVQDEPKKSVYPLARDVSGKDPVYVGRVHRDPENPKMWLMWVVSDNIRKGAALNGIQIAE
KIFFN

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=327, Percent_Identity=31.8042813455657, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1789841, Length=358, Percent_Identity=27.9329608938547, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320362, Length=381, Percent_Identity=28.8713910761155, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 35775; Mature: 35644

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGATGMVGQTFMNILSERSFPIEELRPFASENSLGKKIELQGQQWPCQVLKDGCFDGLDL
CCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCEEEECCCCCCHHHHHCCCCCCEEE
VFFSSGDDISAEWAPKAVAAGAFAVDNSAAFRMDPNTVLIVPEVNGDLVNKDSKPQIIAN
EEEECCCCCCCCCCCHHHHCCEEEECCCEEEEECCCEEEEEECCCCCCCCCCCCCCEEEC
PNCSTIQLVVALKPLLEKFGLEEVRVSTYQAVSGAGQGGHDELIEQTTNHPKPTDPKTFP
CCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCC
HTILFNCIPQIGSFNDEGYCSEEVKIMKETRKILGQKDLKVSAFTVRIPALNAHSESVWV
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCEEEE
TLNKSVSRDEVMAALSGQEGIVVQDEPKKSVYPLARDVSGKDPVYVGRVHRDPENPKMWL
EECCCCCHHHHHHHHCCCCCEEECCCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCEEE
MWVVSDNIRKGAALNGIQIAEKIFFN
EEEEECCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
GATGMVGQTFMNILSERSFPIEELRPFASENSLGKKIELQGQQWPCQVLKDGCFDGLDL
CCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCEEEECCCCCCHHHHHCCCCCCEEE
VFFSSGDDISAEWAPKAVAAGAFAVDNSAAFRMDPNTVLIVPEVNGDLVNKDSKPQIIAN
EEEECCCCCCCCCCCHHHHCCEEEECCCEEEEECCCEEEEEECCCCCCCCCCCCCCEEEC
PNCSTIQLVVALKPLLEKFGLEEVRVSTYQAVSGAGQGGHDELIEQTTNHPKPTDPKTFP
CCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCC
HTILFNCIPQIGSFNDEGYCSEEVKIMKETRKILGQKDLKVSAFTVRIPALNAHSESVWV
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCEEEE
TLNKSVSRDEVMAALSGQEGIVVQDEPKKSVYPLARDVSGKDPVYVGRVHRDPENPKMWL
EECCCCCHHHHHHHHCCCCCEEECCCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCEEE
MWVVSDNIRKGAALNGIQIAEKIFFN
EEEEECCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]