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The map label for this gene is sufC [H]

Identifier: 42521819

GI number: 42521819

Start: 173461

End: 174219

Strand: Direct

Name: sufC [H]

Synonym: Bd0187

Alternate gene names: 42521819

Gene position: 173461-174219 (Clockwise)

Preceding gene: 42521818

Following gene: 42521820

Centisome position: 4.59

GC content: 47.04

Gene sequence:

>759_bases
ATGAATTTACTAGAGATCAAAAACCTACATGCAAGAGTTGAAGAAAAAGAAATCCTGAAAGGTCTGAACCTGACAGTGAA
ACCGGGTGAAGTTCATGCCATCATGGGCCCGAACGGTTCCGGTAAATCCACACTTTCTAAAGTGCTTGCCGGTCACCCGG
CGTATGAAGTCACTTCCGGTGAAGTGAAATACGAAGTGAACTTCAACATGACCAATTTGTTGGATCTTGAGCCGGATGAA
AGAGCCAAAGAAGGCATCTTCCTGGCATTCCAGTATCCGATTGAGGTTCCGGGTGTTTCCAATTTCACGTTCCTGCATAC
GGCTTTCAACTCTGTATTGCAGCACCAGGGTTCTGAACCAATGCCGGAAGGTGAGTTCCGTGAATTCCTTTATCAGAAAA
TGAAACTGGTCAGCATGAAGCCTGAATACCTGGATCGCCCGGTGAACACAGGTTTTTCTGGTGGTGAGAAAAAGAAAAAT
GAAATTCTGCAGATGGCGGTTTTATCCCCGCGTCTGGCGCTTTTGGATGAAACAGATTCCGGTCTGGACATCGATGCTTT
GCGTGTTGTTTCTGAAGGGGTGAACAAACTTCGCCGTAAAGACAACGCGATCATTCTGGTCACTCACTATCAGCGTCTGT
TGGATTATATCAAACCGGACTTCGTTCACGTTTTGGCCAACGGCAAAATCATCGAGACTGGCGACAGCTCTTTGGCGCTG
AAGCTGGAAGAAAAAGGCTACGACTGGCTGACGGTATAG

Upstream 100 bases:

>100_bases
ATTCTCTGTCGAAGCCGTAAAACTGATCGAAATGAAACTTGAGAATAGTGTCGGCTAGGGCCGGCAGAGCGTAGCTGAAG
CAGCTCAATAAAGGTGAAAT

Downstream 100 bases:

>100_bases
GAAGTGACTATGAACCTGTTAACGAGCTATGAAAAATTCAGTCAATCCAACCCTGCAGATGGCGCATTGTCCGCTTTCCG
CAAGGCCGGGTATGACTATG

Product: Iron-regulated ABC transporter ATPase subunit SufC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MNLLEIKNLHARVEEKEILKGLNLTVKPGEVHAIMGPNGSGKSTLSKVLAGHPAYEVTSGEVKYEVNFNMTNLLDLEPDE
RAKEGIFLAFQYPIEVPGVSNFTFLHTAFNSVLQHQGSEPMPEGEFREFLYQKMKLVSMKPEYLDRPVNTGFSGGEKKKN
EILQMAVLSPRLALLDETDSGLDIDALRVVSEGVNKLRRKDNAIILVTHYQRLLDYIKPDFVHVLANGKIIETGDSSLAL
KLEEKGYDWLTV

Sequences:

>Translated_252_residues
MNLLEIKNLHARVEEKEILKGLNLTVKPGEVHAIMGPNGSGKSTLSKVLAGHPAYEVTSGEVKYEVNFNMTNLLDLEPDE
RAKEGIFLAFQYPIEVPGVSNFTFLHTAFNSVLQHQGSEPMPEGEFREFLYQKMKLVSMKPEYLDRPVNTGFSGGEKKKN
EILQMAVLSPRLALLDETDSGLDIDALRVVSEGVNKLRRKDNAIILVTHYQRLLDYIKPDFVHVLANGKIIETGDSSLAL
KLEEKGYDWLTV
>Mature_252_residues
MNLLEIKNLHARVEEKEILKGLNLTVKPGEVHAIMGPNGSGKSTLSKVLAGHPAYEVTSGEVKYEVNFNMTNLLDLEPDE
RAKEGIFLAFQYPIEVPGVSNFTFLHTAFNSVLQHQGSEPMPEGEFREFLYQKMKLVSMKPEYLDRPVNTGFSGGEKKKN
EILQMAVLSPRLALLDETDSGLDIDALRVVSEGVNKLRRKDNAIILVTHYQRLLDYIKPDFVHVLANGKIIETGDSSLAL
KLEEKGYDWLTV

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787972, Length=249, Percent_Identity=59.4377510040161, Blast_Score=307, Evalue=4e-85,
Organism=Escherichia coli, GI1788225, Length=242, Percent_Identity=27.6859504132231, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790525, Length=204, Percent_Identity=28.4313725490196, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786398, Length=229, Percent_Identity=27.5109170305677, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786345, Length=233, Percent_Identity=27.8969957081545, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=247, Percent_Identity=29.5546558704453, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71996809, Length=225, Percent_Identity=29.3333333333333, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI212646699, Length=241, Percent_Identity=29.045643153527, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193211017, Length=225, Percent_Identity=28.8888888888889, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193211015, Length=225, Percent_Identity=28.8888888888889, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25146777, Length=236, Percent_Identity=28.8135593220339, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17569143, Length=222, Percent_Identity=27.027027027027, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569145, Length=222, Percent_Identity=27.4774774774775, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28574744, Length=224, Percent_Identity=27.6785714285714, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 28255; Mature: 28255

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLEIKNLHARVEEKEILKGLNLTVKPGEVHAIMGPNGSGKSTLSKVLAGHPAYEVTSG
CCCHHHHHHHHHCCHHHHHCCCCEEECCCCEEEEECCCCCCHHHHHHHHHCCCCEEECCC
EVKYEVNFNMTNLLDLEPDERAKEGIFLAFQYPIEVPGVSNFTFLHTAFNSVLQHQGSEP
EEEEEEECCEEEEEECCCCCHHHCCEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCCCC
MPEGEFREFLYQKMKLVSMKPEYLDRPVNTGFSGGEKKKNEILQMAVLSPRLALLDETDS
CCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCC
GLDIDALRVVSEGVNKLRRKDNAIILVTHYQRLLDYIKPDFVHVLANGKIIETGDSSLAL
CCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCEEEEEECCEEEEECCCEEEE
KLEEKGYDWLTV
EECCCCCCEECC
>Mature Secondary Structure
MNLLEIKNLHARVEEKEILKGLNLTVKPGEVHAIMGPNGSGKSTLSKVLAGHPAYEVTSG
CCCHHHHHHHHHCCHHHHHCCCCEEECCCCEEEEECCCCCCHHHHHHHHHCCCCEEECCC
EVKYEVNFNMTNLLDLEPDERAKEGIFLAFQYPIEVPGVSNFTFLHTAFNSVLQHQGSEP
EEEEEEECCEEEEEECCCCCHHHCCEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCCCC
MPEGEFREFLYQKMKLVSMKPEYLDRPVNTGFSGGEKKKNEILQMAVLSPRLALLDETDS
CCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCC
GLDIDALRVVSEGVNKLRRKDNAIILVTHYQRLLDYIKPDFVHVLANGKIIETGDSSLAL
CCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCEEEEEECCEEEEECCCEEEE
KLEEKGYDWLTV
EECCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]