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The map label for this gene is hypC1

Identifier: 38637683

GI number: 38637683

Start: 11209

End: 11481

Strand: Direct

Name: hypC1

Synonym: PHG015

Alternate gene names: 38637683

Gene position: 11209-11481 (Clockwise)

Preceding gene: 38637682

Following gene: 38637684

Centisome position: 2.48

GC content: 58.97

Gene sequence:

>273_bases
ATGTGCCTAGCGATTCCCGCACGTTTGGTGGAACTGCAAGCGGACCAGCAGGGCGTAGTCGACCTGAGCGGTGTACGTAA
GACCATATCTCTCGCGCTGATGGCCGATGCCGTAGTCGGTGACTACGTCATCGTGCATGTCGGCTACGCGATTGGCAAGA
TCGATCCAGAGGAAGCAGAACGCACGCTGCGTCTGTTCGCGGAATTGGAGCGAGTGCAGCCGCCTGCGTCCGAGCCGATG
CATGGGATGAACATTCATCAGGAGCCGGCATGA

Upstream 100 bases:

>100_bases
GCGGCGATGCAGGGCTCGCGCTGGGGCAAGCCTGGGTCGCGGCCCGCCAGCCTACGGCTGCCCTGGCGCCGCAAACGCAT
CTACAGGAGGAGGGCGCGCC

Downstream 100 bases:

>100_bases
AATACATCGAAGAATTTCGCGACGGCGAGCTGGCGCAACGCATTGCGGCGCACGTTCGCGCTGAGGCGCGGCCGGGGCAA
CGCTACAACTTCATGGAGTT

Product: HypC1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 90; Mature: 90

Protein sequence:

>90_residues
MCLAIPARLVELQADQQGVVDLSGVRKTISLALMADAVVGDYVIVHVGYAIGKIDPEEAERTLRLFAELERVQPPASEPM
HGMNIHQEPA

Sequences:

>Translated_90_residues
MCLAIPARLVELQADQQGVVDLSGVRKTISLALMADAVVGDYVIVHVGYAIGKIDPEEAERTLRLFAELERVQPPASEPM
HGMNIHQEPA
>Mature_90_residues
MCLAIPARLVELQADQQGVVDLSGVRKTISLALMADAVVGDYVIVHVGYAIGKIDPEEAERTLRLFAELERVQPPASEPM
HGMNIHQEPA

Specific function: Is Required For The Formation Of All Three Hydrogenase Isoenzymes. May Bind To The Precursor Form Of The Large Subunit Of Dehydrogenases To Keep Them In A Conformation Accessible For Metal Incorporation. [C]

COG id: COG0298

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hupF/hypC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPC_CUPNH (P31900)

Other databases:

- EMBL:   X70183
- EMBL:   AY305378
- PIR:   S29977
- RefSeq:   NP_942657.1
- ProteinModelPortal:   P31900
- SMR:   P31900
- GeneID:   2656436
- GenomeReviews:   AY305378_GR
- KEGG:   reh:PHG015
- HOGENOM:   HBG556935
- OMA:   TLAMFGE
- ProtClustDB:   CLSK648202
- BioCyc:   REUT381666:PHG015-MONOMER
- InterPro:   IPR019812
- InterPro:   IPR001109
- PRINTS:   PR00445
- TIGRFAMs:   TIGR00074

Pfam domain/function: PF01455 HupF_HypC

EC number: NA

Molecular weight: Translated: 9790; Mature: 9790

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS01097 HUPF_HYPC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCLAIPARLVELQADQQGVVDLSGVRKTISLALMADAVVGDYVIVHVGYAIGKIDPEEAE
CCCCCCHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEEECHHHCCCCHHHHH
RTLRLFAELERVQPPASEPMHGMNIHQEPA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MCLAIPARLVELQADQQGVVDLSGVRKTISLALMADAVVGDYVIVHVGYAIGKIDPEEAE
CCCCCCHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEEECHHHCCCCHHHHH
RTLRLFAELERVQPPASEPMHGMNIHQEPA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8352644; 12948488