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The map label for this gene is hypD1

Identifier: 38637684

GI number: 38637684

Start: 11478

End: 12617

Strand: Direct

Name: hypD1

Synonym: PHG016

Alternate gene names: 38637684

Gene position: 11478-12617 (Clockwise)

Preceding gene: 38637683

Following gene: 38637685

Centisome position: 2.54

GC content: 61.75

Gene sequence:

>1140_bases
ATGAAATACATCGAAGAATTTCGCGACGGCGAGCTGGCGCAACGCATTGCGGCGCACGTTCGCGCTGAGGCGCGGCCGGG
GCAACGCTACAACTTCATGGAGTTCTGCGGCGGACACACGCATGCCATTTCGCGTTACGGCGTGACCGAACTGCTGCCCG
AGAACGTGCGGATGATTCACGGGCCGGGCTGCCCAGTGTGCGTGCTGCCGATCGGCCGCATTGACCTAGCGCTGCATCTG
GCGCTGGAGCGCGACGCCATCGTCTGCACTTACGGCGACACGATGCGGGTGCCGGCCTCGGGGGGCATGTCGTTGATTCG
GGCCAAGGCGCACGGGGCCGACATCCGCATGGTCTACTCGGCCGCTGATGCGCTGAAAATTGCGCAGCGGCATCCACAGC
GCGAGGTGGTGTTCCTTGCCATTGGCTTCGAGACTACAACGCCTCCAACTGCGCTGATTATTCGCGAGGCGAAGGCGCGC
CAGGTGGATAACTTCAGTGTGTTGTGTTGCCACGTGCTTACGCCGTCGGCCATTACCCACATCCTGGAGTCGCCCGAGGT
GCGCGACTATGGCACTGTGCCCATCGACGGATTCGTTGGGCCGGCTCATGTGAGTATCGTGATCGGTACCCGGCCCTATG
AGCATTTTTCACGCGAGTACGGTAAGCCGGTGGTGATCGCAGGCTTCGAGCCGCTCGATGTGATGCAAGCCATTCTGATG
TTGGTACGACAAGTCAACAGCGGACGCGCAGAGGTGGAAAATGAGTTCGTGCGCGCTGTCACCCGCGATGGCAACGAGAG
CGCGCAGGCCATGGTGTCGGAAGTGTTCGAGCTGCGGCCGTCTTTCGAGTGGCGAGGACTCGGCGAGGTGCCATATAGCG
CCTTGCGCATCCGCGCGCAGTTTGCGCGTTTCGACGCTGAGCAACGCTTCGATCTGCGCTACCGGCCGGTGCCTGACAAT
AAGGCTTGCGAATGCGGCGCGATCTTGCGTGGCGTCAAGAAGCCAACCGACTGCAAGCTGTTCGCTACCGTCTGCACCCC
GGAGAATCCGATGGGGTCGTGCATGGTATCCAGCGAAGGTGCCTGCGCCGCGCACTATTCGTATGGGCGGTTCAAGGATA
TCCCCTTGGTGGCAGCATGA

Upstream 100 bases:

>100_bases
AGGAAGCAGAACGCACGCTGCGTCTGTTCGCGGAATTGGAGCGAGTGCAGCCGCCTGCGTCCGAGCCGATGCATGGGATG
AACATTCATCAGGAGCCGGC

Downstream 100 bases:

>100_bases
GCGGCACCGTTAAACTGGGCTATCAACGGCCCCTGAACATCAAGAGCGGCAGAATCGACATGGGCCACGGCGCGGGGGGG
CGCGCAGCCGCACAACTTAT

Product: HypD1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKYIEEFRDGELAQRIAAHVRAEARPGQRYNFMEFCGGHTHAISRYGVTELLPENVRMIHGPGCPVCVLPIGRIDLALHL
ALERDAIVCTYGDTMRVPASGGMSLIRAKAHGADIRMVYSAADALKIAQRHPQREVVFLAIGFETTTPPTALIIREAKAR
QVDNFSVLCCHVLTPSAITHILESPEVRDYGTVPIDGFVGPAHVSIVIGTRPYEHFSREYGKPVVIAGFEPLDVMQAILM
LVRQVNSGRAEVENEFVRAVTRDGNESAQAMVSEVFELRPSFEWRGLGEVPYSALRIRAQFARFDAEQRFDLRYRPVPDN
KACECGAILRGVKKPTDCKLFATVCTPENPMGSCMVSSEGACAAHYSYGRFKDIPLVAA

Sequences:

>Translated_379_residues
MKYIEEFRDGELAQRIAAHVRAEARPGQRYNFMEFCGGHTHAISRYGVTELLPENVRMIHGPGCPVCVLPIGRIDLALHL
ALERDAIVCTYGDTMRVPASGGMSLIRAKAHGADIRMVYSAADALKIAQRHPQREVVFLAIGFETTTPPTALIIREAKAR
QVDNFSVLCCHVLTPSAITHILESPEVRDYGTVPIDGFVGPAHVSIVIGTRPYEHFSREYGKPVVIAGFEPLDVMQAILM
LVRQVNSGRAEVENEFVRAVTRDGNESAQAMVSEVFELRPSFEWRGLGEVPYSALRIRAQFARFDAEQRFDLRYRPVPDN
KACECGAILRGVKKPTDCKLFATVCTPENPMGSCMVSSEGACAAHYSYGRFKDIPLVAA
>Mature_379_residues
MKYIEEFRDGELAQRIAAHVRAEARPGQRYNFMEFCGGHTHAISRYGVTELLPENVRMIHGPGCPVCVLPIGRIDLALHL
ALERDAIVCTYGDTMRVPASGGMSLIRAKAHGADIRMVYSAADALKIAQRHPQREVVFLAIGFETTTPPTALIIREAKAR
QVDNFSVLCCHVLTPSAITHILESPEVRDYGTVPIDGFVGPAHVSIVIGTRPYEHFSREYGKPVVIAGFEPLDVMQAILM
LVRQVNSGRAEVENEFVRAVTRDGNESAQAMVSEVFELRPSFEWRGLGEVPYSALRIRAQFARFDAEQRFDLRYRPVPDN
KACECGAILRGVKKPTDCKLFATVCTPENPMGSCMVSSEGACAAHYSYGRFKDIPLVAA

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family

Homologues:

Organism=Escherichia coli, GI1789084, Length=376, Percent_Identity=46.2765957446808, Blast_Score=344, Evalue=5e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPD_CUPNH (P31903)

Other databases:

- EMBL:   X70183
- EMBL:   AY305378
- PIR:   S29978
- RefSeq:   NP_942658.1
- ProteinModelPortal:   P31903
- SMR:   P31903
- GeneID:   2656437
- GenomeReviews:   AY305378_GR
- KEGG:   reh:PHG016
- HOGENOM:   HBG287941
- OMA:   GACAAHW
- PhylomeDB:   P31903
- ProtClustDB:   PRK15062
- BioCyc:   REUT381666:PHG016-MONOMER
- InterPro:   IPR002780
- PIRSF:   PIRSF005622
- TIGRFAMs:   TIGR00075

Pfam domain/function: PF01924 HypD

EC number: NA

Molecular weight: Translated: 41908; Mature: 41908

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYIEEFRDGELAQRIAAHVRAEARPGQRYNFMEFCGGHTHAISRYGVTELLPENVRMIH
CCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHCCHHHHCCCCCEEEE
GPGCPVCVLPIGRIDLALHLALERDAIVCTYGDTMRVPASGGMSLIRAKAHGADIRMVYS
CCCCCEEEEECCCEEEEEEEEECCCEEEEECCCEEECCCCCCHHEEEECCCCCCEEEEEH
AADALKIAQRHPQREVVFLAIGFETTTPPTALIIREAKARQVDNFSVLCCHVLTPSAITH
HHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEEECHHHCCCCCCEEEEEEHHCHHHHHH
ILESPEVRDYGTVPIDGFVGPAHVSIVIGTRPYEHFSREYGKPVVIAGFEPLDVMQAILM
HHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCEEEECCCHHHHHHHHHH
LVRQVNSGRAEVENEFVRAVTRDGNESAQAMVSEVFELRPSFEWRGLGEVPYSALRIRAQ
HHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
FARFDAEQRFDLRYRPVPDNKACECGAILRGVKKPTDCKLFATVCTPENPMGSCMVSSEG
HHHCCCCCCCCEEECCCCCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCCCCCEEECCCC
ACAAHYSYGRFKDIPLVAA
CEEEECCCCCCCCCCEECC
>Mature Secondary Structure
MKYIEEFRDGELAQRIAAHVRAEARPGQRYNFMEFCGGHTHAISRYGVTELLPENVRMIH
CCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHCCHHHHCCCCCEEEE
GPGCPVCVLPIGRIDLALHLALERDAIVCTYGDTMRVPASGGMSLIRAKAHGADIRMVYS
CCCCCEEEEECCCEEEEEEEEECCCEEEEECCCEEECCCCCCHHEEEECCCCCCEEEEEH
AADALKIAQRHPQREVVFLAIGFETTTPPTALIIREAKARQVDNFSVLCCHVLTPSAITH
HHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEEECHHHCCCCCCEEEEEEHHCHHHHHH
ILESPEVRDYGTVPIDGFVGPAHVSIVIGTRPYEHFSREYGKPVVIAGFEPLDVMQAILM
HHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCEEEECCCHHHHHHHHHH
LVRQVNSGRAEVENEFVRAVTRDGNESAQAMVSEVFELRPSFEWRGLGEVPYSALRIRAQ
HHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
FARFDAEQRFDLRYRPVPDNKACECGAILRGVKKPTDCKLFATVCTPENPMGSCMVSSEG
HHHCCCCCCCCEEECCCCCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCCCCCEEECCCC
ACAAHYSYGRFKDIPLVAA
CEEEECCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8352644; 12948488