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The map label for this gene is hypF1

Identifier: 38637682

GI number: 38637682

Start: 10034

End: 11218

Strand: Direct

Name: hypF1

Synonym: PHG014

Alternate gene names: 38637682

Gene position: 10034-11218 (Clockwise)

Preceding gene: 38637681

Following gene: 38637683

Centisome position: 2.22

GC content: 67.68

Gene sequence:

>1185_bases
ATGCGAGCGCAGACCTTGCCAGCCGGCAGCGACCATGCGCCGGTGCTGGCTTGCGGTGCATGGCTGAAGAATGCCGCATG
CCTGTTGCGGGGCGCCGAGGTCCTCTGGTCCCCGATACATGGCGATCTTGGAGATCCGGCCAACTGCGATGCGCTTGACC
AGTCGGTCGAACAGTTACTTGACAGCGCTCACGGCCAGGTGCAGGCGGTGGCGCATGATCTGCACCCGGATTTCTATAGC
ACGCAACTCGCGCAACGCCTGGCGGCTCGGCTTTGCGTGCCGGCAGTGGCCGTCCAGCACCATCACGCGCACATCGCCGC
GCTGATGGCGGAATACGATCTGAGAGAACCCGTGATCGGCTTGGCGCTGGACGGCGTCGGTCTTGGCACGGATGGTACGG
CTTGGGGTGGGGAGTTGCTATGGGTTTCTCCGTCAGAGTGGTGTCGCTTGGGGCATCTCCAGTCGCTGCCGCTGCCTGGC
GGCGACGTGGCAGCGCGCGAACCCTGGCGCATGGCAGCCGCAGCGCTACATGTGCTGGACCGTACGGGCGAGATCGGGCG
GCGCTACGGCGCCGTTGTAGGTGAGCAGGCGGCCCGTACCGTGGCAGCGATGCTGGAACGGCAACTCAACTGTCCACGAT
CCAGTAGCGCCGGGCGCTGGTTCGACGCCGCGGCGGGTGCGCTGGGTGTCAGTGTGCGGCAGCAGGCCGAGGCGCAGGCT
GCGATCGCCCTGGAGGCGCTTGCGGCCGACTATCTGTCCGCGCTGTCGCCGCCTGAATGCGTCGGTACGTACGTCGTGGA
TCAGGACGGAGTTCTGGATCTGCGTGGGCTGCTGGAGCAGCTGTTTGCGCTGGCCGATGAGGGTCAGGCGGGGCAAGCGG
CGCGGGGCGCGGCGCTGTTCCATGTGGCGCTCGCCGAGGCTCTGGTGGGGTGGGCCGCTGACGCAGCGCAGGGCCACGGA
CTGAAGACCGTGGCCCTGGGCGGTGGATGTTTCATGAATGGCATTTTGAGCGCCAGCGTGCAAGCCGGATTGGCAGCGCG
AGGTTTGCAAGCGTTGCTGCCGCGCGCGGTATCGTGCGGCGATGCAGGGCTCGCGCTGGGGCAAGCCTGGGTCGCGGCCC
GCCAGCCTACGGCTGCCCTGGCGCCGCAAACGCATCTACAGGAGGAGGGCGCGCCATGTGCCTAG

Upstream 100 bases:

>100_bases
ACGGATGGCGCGCGCATGCGTATCGCCGCGCCGGAGGCCGGAATCGCTGCCCTCGGAACGCAGTTGGCTCCCGGTCCGGC
GGTGTCGAAGGAGATGTGAG

Downstream 100 bases:

>100_bases
CGATTCCCGCACGTTTGGTGGAACTGCAAGCGGACCAGCAGGGCGTAGTCGACCTGAGCGGTGTACGTAAGACCATATCT
CTCGCGCTGATGGCCGATGC

Product: HypF1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MRAQTLPAGSDHAPVLACGAWLKNAACLLRGAEVLWSPIHGDLGDPANCDALDQSVEQLLDSAHGQVQAVAHDLHPDFYS
TQLAQRLAARLCVPAVAVQHHHAHIAALMAEYDLREPVIGLALDGVGLGTDGTAWGGELLWVSPSEWCRLGHLQSLPLPG
GDVAAREPWRMAAAALHVLDRTGEIGRRYGAVVGEQAARTVAAMLERQLNCPRSSSAGRWFDAAAGALGVSVRQQAEAQA
AIALEALAADYLSALSPPECVGTYVVDQDGVLDLRGLLEQLFALADEGQAGQAARGAALFHVALAEALVGWAADAAQGHG
LKTVALGGGCFMNGILSASVQAGLAARGLQALLPRAVSCGDAGLALGQAWVAARQPTAALAPQTHLQEEGAPCA

Sequences:

>Translated_394_residues
MRAQTLPAGSDHAPVLACGAWLKNAACLLRGAEVLWSPIHGDLGDPANCDALDQSVEQLLDSAHGQVQAVAHDLHPDFYS
TQLAQRLAARLCVPAVAVQHHHAHIAALMAEYDLREPVIGLALDGVGLGTDGTAWGGELLWVSPSEWCRLGHLQSLPLPG
GDVAAREPWRMAAAALHVLDRTGEIGRRYGAVVGEQAARTVAAMLERQLNCPRSSSAGRWFDAAAGALGVSVRQQAEAQA
AIALEALAADYLSALSPPECVGTYVVDQDGVLDLRGLLEQLFALADEGQAGQAARGAALFHVALAEALVGWAADAAQGHG
LKTVALGGGCFMNGILSASVQAGLAARGLQALLPRAVSCGDAGLALGQAWVAARQPTAALAPQTHLQEEGAPCA
>Mature_394_residues
MRAQTLPAGSDHAPVLACGAWLKNAACLLRGAEVLWSPIHGDLGDPANCDALDQSVEQLLDSAHGQVQAVAHDLHPDFYS
TQLAQRLAARLCVPAVAVQHHHAHIAALMAEYDLREPVIGLALDGVGLGTDGTAWGGELLWVSPSEWCRLGHLQSLPLPG
GDVAAREPWRMAAAALHVLDRTGEIGRRYGAVVGEQAARTVAAMLERQLNCPRSSSAGRWFDAAAGALGVSVRQQAEAQA
AIALEALAADYLSALSPPECVGTYVVDQDGVLDLRGLLEQLFALADEGQAGQAARGAALFHVALAEALVGWAADAAQGHG
LKTVALGGGCFMNGILSASVQAGLAARGLQALLPRAVSCGDAGLALGQAWVAARQPTAALAPQTHLQEEGAPCA

Specific function: Involved in the hydrogenase maturation process

COG id: COG0068

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbamoyltransferase hypF family

Homologues:

Organism=Escherichia coli, GI2367152, Length=377, Percent_Identity=36.604774535809, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPF1_CUPNH (P45805)

Other databases:

- EMBL:   X70183
- EMBL:   AY305378
- PIR:   S62601
- RefSeq:   NP_942656.1
- ProteinModelPortal:   P45805
- IntAct:   P45805
- GeneID:   2656435
- GenomeReviews:   AY305378_GR
- KEGG:   reh:PHG014
- HOGENOM:   HBG376014
- OMA:   SAGRWFD
- ProtClustDB:   CLSK923800
- BioCyc:   REUT381666:PHG014-MONOMER

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 40677; Mature: 40677

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAQTLPAGSDHAPVLACGAWLKNAACLLRGAEVLWSPIHGDLGDPANCDALDQSVEQLL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
DSAHGQVQAVAHDLHPDFYSTQLAQRLAARLCVPAVAVQHHHAHIAALMAEYDLREPVIG
HHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHE
LALDGVGLGTDGTAWGGELLWVSPSEWCRLGHLQSLPLPGGDVAAREPWRMAAAALHVLD
EEECCCCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RTGEIGRRYGAVVGEQAARTVAAMLERQLNCPRSSSAGRWFDAAAGALGVSVRQQAEAQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AIALEALAADYLSALSPPECVGTYVVDQDGVLDLRGLLEQLFALADEGQAGQAARGAALF
HHHHHHHHHHHHHHCCCHHHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
HVALAEALVGWAADAAQGHGLKTVALGGGCFMNGILSASVQAGLAARGLQALLPRAVSCG
HHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAGLALGQAWVAARQPTAALAPQTHLQEEGAPCA
CHHHHHHHHHHHHCCCCHHCCCHHHHHCCCCCCC
>Mature Secondary Structure
MRAQTLPAGSDHAPVLACGAWLKNAACLLRGAEVLWSPIHGDLGDPANCDALDQSVEQLL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
DSAHGQVQAVAHDLHPDFYSTQLAQRLAARLCVPAVAVQHHHAHIAALMAEYDLREPVIG
HHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHE
LALDGVGLGTDGTAWGGELLWVSPSEWCRLGHLQSLPLPGGDVAAREPWRMAAAALHVLD
EEECCCCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RTGEIGRRYGAVVGEQAARTVAAMLERQLNCPRSSSAGRWFDAAAGALGVSVRQQAEAQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AIALEALAADYLSALSPPECVGTYVVDQDGVLDLRGLLEQLFALADEGQAGQAARGAALF
HHHHHHHHHHHHHHCCCHHHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
HVALAEALVGWAADAAQGHGLKTVALGGGCFMNGILSASVQAGLAARGLQALLPRAVSCG
HHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAGLALGQAWVAARQPTAALAPQTHLQEEGAPCA
CHHHHHHHHHHHHCCCCHHCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8352644; 12948488