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The map label for this gene is 37679680

Identifier: 37679680

GI number: 37679680

Start: 1529827

End: 1530978

Strand: Direct

Name: 37679680

Synonym: VV1496

Alternate gene names: NA

Gene position: 1529827-1530978 (Clockwise)

Preceding gene: 37679679

Following gene: 37679681

Centisome position: 45.61

GC content: 49.57

Gene sequence:

>1152_bases
GTGGAGTACTCAATAATGCATAAATGGATCACCTTTCCTCATCGGGAAGGTGTCTGCTCCAAGCAGGCACATGCCGATTT
TCCCGAAGAGGCGATTTACGAACGTGAAGCGGGGCGTAGTGGGTTCTTTGGCCCCGCTGCGCATTTTCATCATCAACATG
CCCCAACAGGCTGGACCGATTGGCAAGGCGATTTAAGACCGAGAGCGTTTGATTTCACTCGCGTGACCAGCGCCAATCAA
GCCTCTCCTTGGAGTGTGCCGCATTTGCTTCACAATCACGAATGTAAAGTTCGAGTCTGGAAAACCCAAACCAAAATGGA
ATTTCTGGCGCGAAATGCCGATGGCGATGAGCTGCTCTTTATCCATCAAGGTAAGGCCGACCTTTACTGTGACTATGGCC
ATTTGTCAGTAGAAGAAGGGGATTACGTGATGATCCCGCGTTCAACCAACTGGCGCTTGGAGCCGTCAGAGGCGATGTTT
ATTTTGATGATTGAAAACACCGATGCGGCGTATTCACTGCCAGAGAAAGGGTTAGTTGGCAATCATGCGGTATTTGACCC
TGCGGTACTTGAAACGCCGTCGATCAACGACCAGTTCAAAGCGCAATACTCAGAGCAAGAGACGCGTGTGGAAGTGAAAC
GCCACGACAGTGTGAGCGTGATTACTTACCCATTCAATCCATTGGATGCCATAGGTTGGCATGGTGATCTCTCCGTAGTG
AAACTGAACTGGCGCGATATACGCCCATTGATGTCTCATCGTTATCACTTGCCACCGTCAGCACACACCACCTTTGTTGG
GAACGGCTTTGTTGTTTGCACCTTCGTGCCGCGTCCTATCGAAAGTGACCCTGGCGCGTTGAAAGTGCCGTTTTATCACA
ACAACGACGATTATGATGAAGTGTTGTTCTACCATGCGGGGGATTTTTTCAGCCGCGACAACATTGAAGCAGGCATGGTG
ACGTTTCACCCGTCGGGCTTTACCCACGGGCCGCATCCTAAGGCATTCAAAGCTGGCCAAGAGTATAAGAAAAAGTTCAC
CGACGAAGTCGCGGTGATGATTGATACGCGCCATGCATTAACGTTTGCACAAGAGCTCGACAGTGTAGAAAACAAAGAAT
ACGTCTACAGTTGGCGTGAAAATCAAAAATAA

Upstream 100 bases:

>100_bases
CCTGTCTTCTTTGAAATCATTCAGCGTAAAGGCAATGAAGGTTTTGGCGAAGGTAACTTCAAAGCGCTATTCGAATCGAT
AGAAGAAGATCAAATTCGCC

Downstream 100 bases:

>100_bases
TACGGACGACAGAACAGCAAGGTTTGAGAAGGGAAGAGAGATGAAATTAGCAACCAAGAAGAATGAGCATCGCGATGGTG
AGTTGATCGTCGTTAGTCGC

Product: homogentisate 1;2-dioxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MEYSIMHKWITFPHREGVCSKQAHADFPEEAIYEREAGRSGFFGPAAHFHHQHAPTGWTDWQGDLRPRAFDFTRVTSANQ
ASPWSVPHLLHNHECKVRVWKTQTKMEFLARNADGDELLFIHQGKADLYCDYGHLSVEEGDYVMIPRSTNWRLEPSEAMF
ILMIENTDAAYSLPEKGLVGNHAVFDPAVLETPSINDQFKAQYSEQETRVEVKRHDSVSVITYPFNPLDAIGWHGDLSVV
KLNWRDIRPLMSHRYHLPPSAHTTFVGNGFVVCTFVPRPIESDPGALKVPFYHNNDDYDEVLFYHAGDFFSRDNIEAGMV
TFHPSGFTHGPHPKAFKAGQEYKKKFTDEVAVMIDTRHALTFAQELDSVENKEYVYSWRENQK

Sequences:

>Translated_383_residues
MEYSIMHKWITFPHREGVCSKQAHADFPEEAIYEREAGRSGFFGPAAHFHHQHAPTGWTDWQGDLRPRAFDFTRVTSANQ
ASPWSVPHLLHNHECKVRVWKTQTKMEFLARNADGDELLFIHQGKADLYCDYGHLSVEEGDYVMIPRSTNWRLEPSEAMF
ILMIENTDAAYSLPEKGLVGNHAVFDPAVLETPSINDQFKAQYSEQETRVEVKRHDSVSVITYPFNPLDAIGWHGDLSVV
KLNWRDIRPLMSHRYHLPPSAHTTFVGNGFVVCTFVPRPIESDPGALKVPFYHNNDDYDEVLFYHAGDFFSRDNIEAGMV
TFHPSGFTHGPHPKAFKAGQEYKKKFTDEVAVMIDTRHALTFAQELDSVENKEYVYSWRENQK
>Mature_383_residues
MEYSIMHKWITFPHREGVCSKQAHADFPEEAIYEREAGRSGFFGPAAHFHHQHAPTGWTDWQGDLRPRAFDFTRVTSANQ
ASPWSVPHLLHNHECKVRVWKTQTKMEFLARNADGDELLFIHQGKADLYCDYGHLSVEEGDYVMIPRSTNWRLEPSEAMF
ILMIENTDAAYSLPEKGLVGNHAVFDPAVLETPSINDQFKAQYSEQETRVEVKRHDSVSVITYPFNPLDAIGWHGDLSVV
KLNWRDIRPLMSHRYHLPPSAHTTFVGNGFVVCTFVPRPIESDPGALKVPFYHNNDDYDEVLFYHAGDFFSRDNIEAGMV
TFHPSGFTHGPHPKAFKAGQEYKKKFTDEVAVMIDTRHALTFAQELDSVENKEYVYSWRENQK

Specific function: Unknown

COG id: COG3508

COG function: function code Q; Homogentisate 1,2-dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the homogentisate dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR005708
- InterPro:   IPR014710 [H]

Pfam domain/function: PF04209 HgmA [H]

EC number: NA

Molecular weight: Translated: 44058; Mature: 44058

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYSIMHKWITFPHREGVCSKQAHADFPEEAIYEREAGRSGFFGPAAHFHHQHAPTGWTD
CCCCEEEHHHCCCCCCCCCCCHHCCCCCHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCC
WQGDLRPRAFDFTRVTSANQASPWSVPHLLHNHECKVRVWKTQTKMEFLARNADGDELLF
CCCCCCCCEEEEEEECCCCCCCCCCCCHHHCCCCEEEEEEECHHHHHHHHCCCCCCEEEE
IHQGKADLYCDYGHLSVEEGDYVMIPRSTNWRLEPSEAMFILMIENTDAAYSLPEKGLVG
EECCCCCEEEECCEEEECCCCEEEEECCCCCEECCCCEEEEEEEECCCCCCCCCCCCCCC
NHAVFDPAVLETPSINDQFKAQYSEQETRVEVKRHDSVSVITYPFNPLDAIGWHGDLSVV
CCCCCCCHHCCCCCCCHHHHHHHCCCHHEEEEEECCCEEEEEECCCCHHHCCCCCCEEEE
KLNWRDIRPLMSHRYHLPPSAHTTFVGNGFVVCTFVPRPIESDPGALKVPFYHNNDDYDE
EECHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCCEEEEEEECCCCCHHH
VLFYHAGDFFSRDNIEAGMVTFHPSGFTHGPHPKAFKAGQEYKKKFTDEVAVMIDTRHAL
EEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHCCHHHHHHHCCCEEEEEECHHHH
TFAQELDSVENKEYVYSWRENQK
HHHHHHHCCCCCEEEEEECCCCC
>Mature Secondary Structure
MEYSIMHKWITFPHREGVCSKQAHADFPEEAIYEREAGRSGFFGPAAHFHHQHAPTGWTD
CCCCEEEHHHCCCCCCCCCCCHHCCCCCHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCC
WQGDLRPRAFDFTRVTSANQASPWSVPHLLHNHECKVRVWKTQTKMEFLARNADGDELLF
CCCCCCCCEEEEEEECCCCCCCCCCCCHHHCCCCEEEEEEECHHHHHHHHCCCCCCEEEE
IHQGKADLYCDYGHLSVEEGDYVMIPRSTNWRLEPSEAMFILMIENTDAAYSLPEKGLVG
EECCCCCEEEECCEEEECCCCEEEEECCCCCEECCCCEEEEEEEECCCCCCCCCCCCCCC
NHAVFDPAVLETPSINDQFKAQYSEQETRVEVKRHDSVSVITYPFNPLDAIGWHGDLSVV
CCCCCCCHHCCCCCCCHHHHHHHCCCHHEEEEEECCCEEEEEECCCCHHHCCCCCCEEEE
KLNWRDIRPLMSHRYHLPPSAHTTFVGNGFVVCTFVPRPIESDPGALKVPFYHNNDDYDE
EECHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCCEEEEEEECCCCCHHH
VLFYHAGDFFSRDNIEAGMVTFHPSGFTHGPHPKAFKAGQEYKKKFTDEVAVMIDTRHAL
EEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHCCHHHHHHHCCCEEEEEECHHHH
TFAQELDSVENKEYVYSWRENQK
HHHHHHHCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]