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The map label for this gene is 37679340

Identifier: 37679340

GI number: 37679340

Start: 1170095

End: 1171033

Strand: Direct

Name: 37679340

Synonym: VV1156

Alternate gene names: NA

Gene position: 1170095-1171033 (Clockwise)

Preceding gene: 37679339

Following gene: 37679341

Centisome position: 34.88

GC content: 50.91

Gene sequence:

>939_bases
ATGATGAGCATCCCTCTGATATATCACCCAATCTACTCTCGGTTGCCCCTACCTGAGGGGCATCGTTACCCGATCATGAA
ATATCACCATCTCTATCAAGCGGTGTGTCGATATCAGCAACAGCATCTCGAGTGGCAGCAGGCATTTGCTTTTTATCAGC
CAGAAGCGTTATCGATTGAAGCCATCAAGCAAGTTCACCAACAAGAATATGTGGATCTGCTGACGACGGGCTTATTGCCT
GCGGCGAAAATGCGCAGAATCGGTTTTCCTTGGAGTGAACAACTGATTGAACGCACGTTAACCTCAACCGCAGGAACTGT
GCTGACAGCGGAAAAAGCCTTACAACATGGCGTTGCGATTCATCTTAGTGGCGGCTATCACCATGCCCATTTCGACTATG
GCAGCGGTTTTTGCTTGTTCAACGATCTCGTGATGGCTGCACATAAAGCGTTGGAACACGCCAGCGTCGACAAAGTGTTG
ATCATCGATAGCGATGTGCATCATGGCGATGGGACGGCAACTTTATGCCAACGGCGCGACGACATTGTGACGCTTTCTTT
CCATTGTGATAAGAACTTTCCTGCCCGTAAGCCGGACTCCGATCTCGATATTGGTTTGCCAAGAGAGTGCGGCGATGAGG
CGTTTCTTGCGGCGTTTAAAGAGGTGGTTCCGATGGCGATACGTCTCCACCAACCGGATCTCATTATCTACGATGCCGGT
GTCGACATTCATCATGAGGATGAGCTCGGATATCTCAACGTCTCCACCGACGCTTTGTATCAACGTGACGCTTTTCTCTT
TGGGCAGGCCAAAGCCAGTGCGATCCCGGTTGCCGCGGTGGTAGGTGGTGGATATCGAACGGATCATGAAGCGCTGGTGC
CACTGCATTTGCAACTGCTCAACGCGGCGTTCGATGTGTATCGTTCGACACCAGATTGA

Upstream 100 bases:

>100_bases
TGGAGCGCCCAGCGTTTAAGCGCAAGAGACGCGCCAGTACCAGCAAGAAAACGGCGTCAACCGCGACCCAAAAAAGAACC
AACAAGTCGGCTTAAACCCC

Downstream 100 bases:

>100_bases
TGCATATTCGTGCCAAGATTTTTGCTCGAAAACGTTGTTTTGACAAAGTGTGCTATGCATCAACTTTCACTATGAATTTG
AATTAATTAAATAAGCGTAC

Product: histone deacetylase/AcuC/AphA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MMSIPLIYHPIYSRLPLPEGHRYPIMKYHHLYQAVCRYQQQHLEWQQAFAFYQPEALSIEAIKQVHQQEYVDLLTTGLLP
AAKMRRIGFPWSEQLIERTLTSTAGTVLTAEKALQHGVAIHLSGGYHHAHFDYGSGFCLFNDLVMAAHKALEHASVDKVL
IIDSDVHHGDGTATLCQRRDDIVTLSFHCDKNFPARKPDSDLDIGLPRECGDEAFLAAFKEVVPMAIRLHQPDLIIYDAG
VDIHHEDELGYLNVSTDALYQRDAFLFGQAKASAIPVAAVVGGGYRTDHEALVPLHLQLLNAAFDVYRSTPD

Sequences:

>Translated_312_residues
MMSIPLIYHPIYSRLPLPEGHRYPIMKYHHLYQAVCRYQQQHLEWQQAFAFYQPEALSIEAIKQVHQQEYVDLLTTGLLP
AAKMRRIGFPWSEQLIERTLTSTAGTVLTAEKALQHGVAIHLSGGYHHAHFDYGSGFCLFNDLVMAAHKALEHASVDKVL
IIDSDVHHGDGTATLCQRRDDIVTLSFHCDKNFPARKPDSDLDIGLPRECGDEAFLAAFKEVVPMAIRLHQPDLIIYDAG
VDIHHEDELGYLNVSTDALYQRDAFLFGQAKASAIPVAAVVGGGYRTDHEALVPLHLQLLNAAFDVYRSTPD
>Mature_312_residues
MMSIPLIYHPIYSRLPLPEGHRYPIMKYHHLYQAVCRYQQQHLEWQQAFAFYQPEALSIEAIKQVHQQEYVDLLTTGLLP
AAKMRRIGFPWSEQLIERTLTSTAGTVLTAEKALQHGVAIHLSGGYHHAHFDYGSGFCLFNDLVMAAHKALEHASVDKVL
IIDSDVHHGDGTATLCQRRDDIVTLSFHCDKNFPARKPDSDLDIGLPRECGDEAFLAAFKEVVPMAIRLHQPDLIIYDAG
VDIHHEDELGYLNVSTDALYQRDAFLFGQAKASAIPVAAVVGGGYRTDHEALVPLHLQLLNAAFDVYRSTPD

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI209862883, Length=248, Percent_Identity=25.8064516129032, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI217272877, Length=190, Percent_Identity=28.4210526315789, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI13128860, Length=262, Percent_Identity=28.6259541984733, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI293336691, Length=232, Percent_Identity=29.3103448275862, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI13128862, Length=259, Percent_Identity=27.027027027027, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI169234807, Length=189, Percent_Identity=30.6878306878307, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI148539870, Length=189, Percent_Identity=30.6878306878307, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI8923769, Length=226, Percent_Identity=25.6637168141593, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI153085395, Length=169, Percent_Identity=34.3195266272189, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI13128864, Length=179, Percent_Identity=30.7262569832402, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI20070354, Length=315, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI30795204, Length=150, Percent_Identity=29.3333333333333, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI30795202, Length=150, Percent_Identity=29.3333333333333, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI17158039, Length=150, Percent_Identity=29.3333333333333, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI193207430, Length=314, Percent_Identity=23.2484076433121, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17561978, Length=256, Percent_Identity=27.34375, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17534739, Length=276, Percent_Identity=27.536231884058, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17508561, Length=255, Percent_Identity=27.0588235294118, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17540332, Length=181, Percent_Identity=30.939226519337, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193206283, Length=181, Percent_Identity=30.939226519337, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17540334, Length=181, Percent_Identity=30.939226519337, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537347, Length=175, Percent_Identity=31.4285714285714, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321244, Length=259, Percent_Identity=28.1853281853282, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323999, Length=262, Percent_Identity=29.3893129770992, Blast_Score=93, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324307, Length=271, Percent_Identity=25.4612546125461, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325325, Length=134, Percent_Identity=32.089552238806, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24649807, Length=270, Percent_Identity=27.037037037037, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24657891, Length=262, Percent_Identity=27.8625954198473, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24644244, Length=293, Percent_Identity=25.5972696245734, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281360899, Length=261, Percent_Identity=26.4367816091954, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24642144, Length=209, Percent_Identity=27.7511961722488, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24642146, Length=261, Percent_Identity=26.4367816091954, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24642142, Length=261, Percent_Identity=26.4367816091954, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281360799, Length=199, Percent_Identity=32.1608040201005, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641720, Length=199, Percent_Identity=32.1608040201005, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281360801, Length=199, Percent_Identity=32.1608040201005, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 35019; Mature: 35019

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSIPLIYHPIYSRLPLPEGHRYPIMKYHHLYQAVCRYQQQHLEWQQAFAFYQPEALSIE
CCCCCEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AIKQVHQQEYVDLLTTGLLPAAKMRRIGFPWSEQLIERTLTSTAGTVLTAEKALQHGVAI
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCEEE
HLSGGYHHAHFDYGSGFCLFNDLVMAAHKALEHASVDKVLIIDSDVHHGDGTATLCQRRD
EEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHCCCC
DIVTLSFHCDKNFPARKPDSDLDIGLPRECGDEAFLAAFKEVVPMAIRLHQPDLIIYDAG
CEEEEEEEECCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHEEECCCCEEEEECC
VDIHHEDELGYLNVSTDALYQRDAFLFGQAKASAIPVAAVVGGGYRTDHEALVPLHLQLL
CCEEECCCCCEEEECHHHHHHHCCEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHHH
NAAFDVYRSTPD
HHHHHHHCCCCC
>Mature Secondary Structure
MMSIPLIYHPIYSRLPLPEGHRYPIMKYHHLYQAVCRYQQQHLEWQQAFAFYQPEALSIE
CCCCCEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AIKQVHQQEYVDLLTTGLLPAAKMRRIGFPWSEQLIERTLTSTAGTVLTAEKALQHGVAI
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCEEE
HLSGGYHHAHFDYGSGFCLFNDLVMAAHKALEHASVDKVLIIDSDVHHGDGTATLCQRRD
EEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHCCCC
DIVTLSFHCDKNFPARKPDSDLDIGLPRECGDEAFLAAFKEVVPMAIRLHQPDLIIYDAG
CEEEEEEEECCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHEEECCCCEEEEECC
VDIHHEDELGYLNVSTDALYQRDAFLFGQAKASAIPVAAVVGGGYRTDHEALVPLHLQLL
CCEEECCCCCEEEECHHHHHHHCCEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHHH
NAAFDVYRSTPD
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]