Click here to switch to the map view.

The map label for this gene is clpX

Identifier: 37679289

GI number: 37679289

Start: 1111192

End: 1112472

Strand: Direct

Name: clpX

Synonym: VV1105

Alternate gene names: 37679289

Gene position: 1111192-1112472 (Clockwise)

Preceding gene: 37679288

Following gene: 37679290

Centisome position: 33.13

GC content: 46.6

Gene sequence:

>1281_bases
ATGACAGACAAAAGCAAAGAGAGTGGTAGTGGTAAGTTGCTTTACTGCTCTTTCTGCGGCAAAAGCCAGCACGAAGTTCG
CAAGCTAATCGCTGGTCCATCCGTTTACATCTGTGACGAATGTGTCGATTTATGTAACGACATCATCCGTGAAGAGATCA
AAGATGTGCTTCCAAAACGCGAATCTGAAGCGTTGCCAACGCCTCGTGAGATCCGTGCACACCTTGATGACTATGTAATC
GGTCAGGACCATGCGAAAAAAGTGCTCGCGGTTGCGGTATATAACCACTACAAGCGTTTACGTAATGGTGACACAACGAG
TGATGGCGTGGAGCTAGGTAAGAGTAACATCTTGCTGATCGGCCCAACAGGTAGCGGTAAGACGTTGCTTGCTGAGACGC
TTGCGCGTTTCCTCGATGTACCGTTCACTATGGCAGATGCCACGACGCTAACAGAAGCGGGTTATGTGGGCGAAGATGTT
GAAAACATCATTCAAAAGTTGCTTCAGAAATGTGATTACGACGTAGCGAAAGCAGAGCGTGGTATTGTGTATATCGATGA
AATTGACAAGATTTCTCGTAAAGCAGAAAACCCATCTATTACTCGTGACGTTTCTGGTGAAGGCGTTCAGCAAGCGCTGC
TTAAACTGGTTGAAGGTACGATTGCTTCTGTACCACCTCAAGGTGGTCGTAAGCATCCTCAGCAAGAGTTTTTGCAAGTG
GATACGTCAAAGATCCTCTTTATCTGTGGTGGTGCATTTGCCGGTCTAGATAAAGTGATCGAACAACGCGTTGCAACAGG
TACAGGCATTGGTTTTGGTGCGGAAGTCCGCTCTAAAGACGAAAGCAAAACAGTGGGCGAACTGTTCACTCAGGTAGAGC
CAGAAGATCTTGTGAAATATGGTTTGATTCCTGAGTTTATTGGTCGTCTACCAGTGACCGCTTCGTTGACCGAGTTAGAC
GAAGAAGCATTAATTCAGATTCTTTGCCAACCAAAAAATGCGCTAACAAAGCAATATGCAGCGCTGTTTGAACTGGAAGG
TGCGGATCTTGAGTTCAGAGAAGATGCGCTAAAAGCGATCGCGAAAAAAGCGATGGAGCGTAAAACAGGCGCTCGTGGCT
TGCGTTCAATTTTGGAAGGCGTGTTGCTAGAAACCATGTATGAACTGCCATCGATGGACGACGTGAGCAAAGTTGTCATT
GATGAATCGGTGATTAATGGTGAATCAGAGCCGCTTTTGATTTACACCAACAGTGATAGCCAAGCCGCTGGCGCTGAGTA
A

Upstream 100 bases:

>100_bases
GACGCAGTATTGACTCATCGCAGTGCATAATTTGCCTGCGCAAACTGATTCAAATTGTTATACACTCAAACATAAAGAGT
AAAGGCTAAGAGGTTAGCGA

Downstream 100 bases:

>100_bases
ATTTAATCGATGTAGAAAAAGGAGGTAAGGAATTACCTCCTTTTTTATTTTCTTTTATTGAATCCAAATAATTAGCCCCC
ATATACTGCTCATAATAGTA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MTDKSKESGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVLPKRESEALPTPREIRAHLDDYVI
GQDHAKKVLAVAVYNHYKRLRNGDTTSDGVELGKSNILLIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDV
ENIIQKLLQKCDYDVAKAERGIVYIDEIDKISRKAENPSITRDVSGEGVQQALLKLVEGTIASVPPQGGRKHPQQEFLQV
DTSKILFICGGAFAGLDKVIEQRVATGTGIGFGAEVRSKDESKTVGELFTQVEPEDLVKYGLIPEFIGRLPVTASLTELD
EEALIQILCQPKNALTKQYAALFELEGADLEFREDALKAIAKKAMERKTGARGLRSILEGVLLETMYELPSMDDVSKVVI
DESVINGESEPLLIYTNSDSQAAGAE

Sequences:

>Translated_426_residues
MTDKSKESGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVLPKRESEALPTPREIRAHLDDYVI
GQDHAKKVLAVAVYNHYKRLRNGDTTSDGVELGKSNILLIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDV
ENIIQKLLQKCDYDVAKAERGIVYIDEIDKISRKAENPSITRDVSGEGVQQALLKLVEGTIASVPPQGGRKHPQQEFLQV
DTSKILFICGGAFAGLDKVIEQRVATGTGIGFGAEVRSKDESKTVGELFTQVEPEDLVKYGLIPEFIGRLPVTASLTELD
EEALIQILCQPKNALTKQYAALFELEGADLEFREDALKAIAKKAMERKTGARGLRSILEGVLLETMYELPSMDDVSKVVI
DESVINGESEPLLIYTNSDSQAAGAE
>Mature_425_residues
TDKSKESGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVLPKRESEALPTPREIRAHLDDYVIG
QDHAKKVLAVAVYNHYKRLRNGDTTSDGVELGKSNILLIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVAKAERGIVYIDEIDKISRKAENPSITRDVSGEGVQQALLKLVEGTIASVPPQGGRKHPQQEFLQVD
TSKILFICGGAFAGLDKVIEQRVATGTGIGFGAEVRSKDESKTVGELFTQVEPEDLVKYGLIPEFIGRLPVTASLTELDE
EALIQILCQPKNALTKQYAALFELEGADLEFREDALKAIAKKAMERKTGARGLRSILEGVLLETMYELPSMDDVSKVVID
ESVINGESEPLLIYTNSDSQAAGAE

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=330, Percent_Identity=51.2121212121212, Blast_Score=314, Evalue=1e-85,
Organism=Escherichia coli, GI1786642, Length=426, Percent_Identity=83.5680751173709, Blast_Score=726, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=130, Percent_Identity=40, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=323, Percent_Identity=45.2012383900929, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=323, Percent_Identity=45.2012383900929, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI71988663, Length=402, Percent_Identity=37.3134328358209, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI71988660, Length=255, Percent_Identity=38.8235294117647, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=429, Percent_Identity=38.6946386946387, Blast_Score=269, Evalue=5e-73,
Organism=Drosophila melanogaster, GI24648291, Length=324, Percent_Identity=46.2962962962963, Blast_Score=284, Evalue=7e-77,
Organism=Drosophila melanogaster, GI24648289, Length=324, Percent_Identity=46.2962962962963, Blast_Score=284, Evalue=7e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46543; Mature: 46411

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKSKESGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVLPKR
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCC
ESEALPTPREIRAHLDDYVIGQDHAKKVLAVAVYNHYKRLRNGDTTSDGVELGKSNILLI
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEE
GPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVAKAER
ECCCCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCC
GIVYIDEIDKISRKAENPSITRDVSGEGVQQALLKLVEGTIASVPPQGGRKHPQQEFLQV
CEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
DTSKILFICGGAFAGLDKVIEQRVATGTGIGFGAEVRSKDESKTVGELFTQVEPEDLVKY
CCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHHCCCHHHHHHH
GLIPEFIGRLPVTASLTELDEEALIQILCQPKNALTKQYAALFELEGADLEFREDALKAI
CCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AKKAMERKTGARGLRSILEGVLLETMYELPSMDDVSKVVIDESVINGESEPLLIYTNSDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
QAAGAE
CCCCCC
>Mature Secondary Structure 
TDKSKESGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVLPKR
CCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCC
ESEALPTPREIRAHLDDYVIGQDHAKKVLAVAVYNHYKRLRNGDTTSDGVELGKSNILLI
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEE
GPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVAKAER
ECCCCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCC
GIVYIDEIDKISRKAENPSITRDVSGEGVQQALLKLVEGTIASVPPQGGRKHPQQEFLQV
CEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
DTSKILFICGGAFAGLDKVIEQRVATGTGIGFGAEVRSKDESKTVGELFTQVEPEDLVKY
CCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHHCCCHHHHHHH
GLIPEFIGRLPVTASLTELDEEALIQILCQPKNALTKQYAALFELEGADLEFREDALKAI
CCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AKKAMERKTGARGLRSILEGVLLETMYELPSMDDVSKVVIDESVINGESEPLLIYTNSDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
QAAGAE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA