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The map label for this gene is rbsK [H]

Identifier: 37678712

GI number: 37678712

Start: 511102

End: 512031

Strand: Direct

Name: rbsK [H]

Synonym: VV0528

Alternate gene names: 37678712

Gene position: 511102-512031 (Clockwise)

Preceding gene: 37678701

Following gene: 37678713

Centisome position: 15.24

GC content: 41.29

Gene sequence:

>930_bases
ATGAAAACAATTGCAGTTATCGGCTCAAATATGGTTGATCTCATTTCATACACAGACCGTATGCCAAAAGAAGGTGAAAC
ATTAGAAGCTCCATCATTCAAAATGGGATGTGGTGGGAAAGGTGCTAACCAAGCCGTAGCCGCTGCGAAAATGGGAGCAG
ATGTTGTAATGGTAAGCAAAGTGGGTGACGACATGTTTGCCGACAATACGATTCGAAACTTTCAATCTTACGGCATCAAC
ACTCAATATGTGAGCAAAGTACCTCAGACTTCAAGCGGTGTGGCACCAATATTTGTTAACTCCACATCTCAGAACTCAAT
TTTGATCATTAAAGGAGCTAACGAGTTTTTAAAACCAGATGACATTGATAAAGCAGAAAGTACCTTGGTGGAGTGCAGTT
TGATTGTACTTCAGCTAGAAGTACCACTGGAAACTGTCTATGCCGCCATCGAATTTGGCAACAAGCATAGTATTCCGGTA
TTGCTAAATCCTGCACCTGCTGTACCTGAGCTTGATATTGAATATGCTTGTCGTTGTGATTTCTTCGTCCCTAACGAAAC
TGAACTAGAAATTCTAGTGAACAAGCCTGTTGAAACGGTTGAACAGATTAAAGAAGCAGCCACCATTCTTCTAAATAAAG
GTTTGAACAATATCATCGTTACCATGGGTTCGAAAGGAGCGCTTTGGTTAAGCAAAGATGGTAAAGACGTATTCATTGAG
CCAACCAAAGTAAATGCGGTGGATACCAGTGGTGCGGGGGATGCATTCATTGGCTGCTTCTCTCACTACTTTATGCAAAC
TGGTGATGTACAGAAGTCATTGGAAAAAGCTTCACTGTTTGCTGCATTCAGTGTGACGGAAAAAGGAACACAGTTCTCTT
ATCCGAGCATTGAACAATTCGAAGAGTTTGAAACAAAGCACTCTAAATAA

Upstream 100 bases:

>100_bases
TTTAATAGGCGATCACATCATTTAAGTGATCTCAATCTCAGTAAATACTCATTAAGATCGATTAATGTTAGTTTTATAAC
ATCAGTAAGGAAGGTTAATA

Downstream 100 bases:

>100_bases
TACTAACGGTCTGAACTGACAATTAAAACTGGCTCATTATTTCTAATGAGCCACAGATAACTTGTTCTTTAAGGAACCCT
ACAATGATAAAAAATAATAC

Product: sugar kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MKTIAVIGSNMVDLISYTDRMPKEGETLEAPSFKMGCGGKGANQAVAAAKMGADVVMVSKVGDDMFADNTIRNFQSYGIN
TQYVSKVPQTSSGVAPIFVNSTSQNSILIIKGANEFLKPDDIDKAESTLVECSLIVLQLEVPLETVYAAIEFGNKHSIPV
LLNPAPAVPELDIEYACRCDFFVPNETELEILVNKPVETVEQIKEAATILLNKGLNNIIVTMGSKGALWLSKDGKDVFIE
PTKVNAVDTSGAGDAFIGCFSHYFMQTGDVQKSLEKASLFAAFSVTEKGTQFSYPSIEQFEEFETKHSK

Sequences:

>Translated_309_residues
MKTIAVIGSNMVDLISYTDRMPKEGETLEAPSFKMGCGGKGANQAVAAAKMGADVVMVSKVGDDMFADNTIRNFQSYGIN
TQYVSKVPQTSSGVAPIFVNSTSQNSILIIKGANEFLKPDDIDKAESTLVECSLIVLQLEVPLETVYAAIEFGNKHSIPV
LLNPAPAVPELDIEYACRCDFFVPNETELEILVNKPVETVEQIKEAATILLNKGLNNIIVTMGSKGALWLSKDGKDVFIE
PTKVNAVDTSGAGDAFIGCFSHYFMQTGDVQKSLEKASLFAAFSVTEKGTQFSYPSIEQFEEFETKHSK
>Mature_309_residues
MKTIAVIGSNMVDLISYTDRMPKEGETLEAPSFKMGCGGKGANQAVAAAKMGADVVMVSKVGDDMFADNTIRNFQSYGIN
TQYVSKVPQTSSGVAPIFVNSTSQNSILIIKGANEFLKPDDIDKAESTLVECSLIVLQLEVPLETVYAAIEFGNKHSIPV
LLNPAPAVPELDIEYACRCDFFVPNETELEILVNKPVETVEQIKEAATILLNKGLNNIIVTMGSKGALWLSKDGKDVFIE
PTKVNAVDTSGAGDAFIGCFSHYFMQTGDVQKSLEKASLFAAFSVTEKGTQFSYPSIEQFEEFETKHSK

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=291, Percent_Identity=39.1752577319588, Blast_Score=208, Evalue=5e-54,
Organism=Escherichia coli, GI1790193, Length=301, Percent_Identity=36.2126245847176, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI87082343, Length=304, Percent_Identity=27.9605263157895, Blast_Score=91, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17532905, Length=307, Percent_Identity=37.1335504885993, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6319884, Length=325, Percent_Identity=29.5384615384615, Blast_Score=115, Evalue=7e-27,
Organism=Drosophila melanogaster, GI20128807, Length=302, Percent_Identity=36.4238410596026, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24583886, Length=304, Percent_Identity=30.2631578947368, Blast_Score=139, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33508; Mature: 33508

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIAVIGSNMVDLISYTDRMPKEGETLEAPSFKMGCGGKGANQAVAAAKMGADVVMVSK
CCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHCCCCEEEEEE
VGDDMFADNTIRNFQSYGINTQYVSKVPQTSSGVAPIFVNSTSQNSILIIKGANEFLKPD
CCCCHHCCHHHHHHHHCCCCHHHHHCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCC
DIDKAESTLVECSLIVLQLEVPLETVYAAIEFGNKHSIPVLLNPAPAVPELDIEYACRCD
CCCHHHHHHHEEEEEEEEEECCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCEEEEEE
FFVPNETELEILVNKPVETVEQIKEAATILLNKGLNNIIVTMGSKGALWLSKDGKDVFIE
EECCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCEEEEE
PTKVNAVDTSGAGDAFIGCFSHYFMQTGDVQKSLEKASLFAAFSVTEKGTQFSYPSIEQF
CCEECEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHH
EEFETKHSK
HHHHHHCCC
>Mature Secondary Structure
MKTIAVIGSNMVDLISYTDRMPKEGETLEAPSFKMGCGGKGANQAVAAAKMGADVVMVSK
CCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHCCCCEEEEEE
VGDDMFADNTIRNFQSYGINTQYVSKVPQTSSGVAPIFVNSTSQNSILIIKGANEFLKPD
CCCCHHCCHHHHHHHHCCCCHHHHHCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCC
DIDKAESTLVECSLIVLQLEVPLETVYAAIEFGNKHSIPVLLNPAPAVPELDIEYACRCD
CCCHHHHHHHEEEEEEEEEECCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCEEEEEE
FFVPNETELEILVNKPVETVEQIKEAATILLNKGLNNIIVTMGSKGALWLSKDGKDVFIE
EECCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCEEEEE
PTKVNAVDTSGAGDAFIGCFSHYFMQTGDVQKSLEKASLFAAFSVTEKGTQFSYPSIEQF
CCEECEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHH
EEFETKHSK
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]