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The map label for this gene is fucP [H]

Identifier: 37678713

GI number: 37678713

Start: 512115

End: 513443

Strand: Direct

Name: fucP [H]

Synonym: VV0529

Alternate gene names: 37678713

Gene position: 512115-513443 (Clockwise)

Preceding gene: 37678712

Following gene: 37678714

Centisome position: 15.27

GC content: 38.68

Gene sequence:

>1329_bases
ATGATAAAAAATAATACCATCCAAGGCTCTGATGGCTATTTGGATAAAACACCAGTATTTCAATTCATACTATTATCTTG
CCTTTTTCCTTTATGGGGATGTGCGGCTGCATTAAACGATATTCTAATTACTCAATTTAAATCTGTCTTTGAGTTATCTA
ACTTTGCAAGTGCCTTAGTGCAAAGTGCTTTTTATGGTGGTTATTTTCTAATTGCAATCCCTGCTTCTTTAGTTATTAAA
AAGTCGTCGTATAAAATGGCTATTATGATTGGTTTGTCGCTTTATATCTTTGGTTGCGCTGCATTTTTCCCAGCTTCTCA
TATGGCAACTTATACTATGTTCCTAGCTGCGATTTTCGCTATTGCTGTGGGTTTGTCTTTTCTTGAAACAGCGGCGAATA
CATATTCTTCAATGTTGGGACCAAAATCCCATGCAACACTGCGTTTGAACATCAGCCAAACTTTCTATCCAATAGGTGCT
ATTGCGGGTATCTTGCTTGGTAAATACCTTATTTTCCAAGACGGTGCTAGCTTAGAATCACAAATGGCGACAATGTCTCC
AGATCAGATTCATGCGTTCCGTCTGGAGATGCTAGAGTATACGCTGAAGCCTTATAAGTACATCATTTTCATTCTCATCG
GTGTGTTAGCGTTGTTTATGTTCACTCAATACCCGAAATGTAAAGTGGCTCAACAAAGTGGTAAAAAAGCCCCTTCTATT
GGTAAAACGCTTAAGTATTTATCGACTAATAATCGCTTCAAAAAAGGCATCATTGCACAGTTCTTATATGTAGGTATGCA
GGTCGCGGTGTGGTCGTTCACGATACGTTTAGCATTAGAAATGTCTGATATCAACGAACGCGCAGCATCAAACTATATGG
TGTACTCATTCGTGTGTTTCTTTATAGGTAAATTTATTGCCAACATCCTGATGACAAAATTCTCTGCTGAGAAAGTACTC
ATTGTTTATTCTTTGATTGGTATGGCGTTTCTTGCTTATGTATCTCTAGTTCACGATTTTAGCGCGGTATACGTAGCTGT
TGGTGTGAGTGTTTTGTTCGGTCCTTGTTGGGCAACTATCTACGCTGGTACATTAGATACGGTAGATAACGAATACACGG
AAACAGCGGGAGCTGTCATTGTTATGGCGATCGTAGGCGCAGCAGTGGTACCTGCTATTCAAGGTTTGGTGGCTGACGCT
ATTGGCATGCAGCTTTCTTTTTTGGTCAACTTTATTTGCTTTGGATACGTTGGTTATTATTTCTTAGGTGAAATGAAAAA
TAAGAACCAAAGCGAAAAACAGACTCAATTAGCAGAACAAACAAATTAA

Upstream 100 bases:

>100_bases
CAAAGCACTCTAAATAATACTAACGGTCTGAACTGACAATTAAAACTGGCTCATTATTTCTAATGAGCCACAGATAACTT
GTTCTTTAAGGAACCCTACA

Downstream 100 bases:

>100_bases
TGTAGCAAAAAGCCACTTTATAAGTGGCTTTTCTGTTCCGGAGAAGATTTATGTATATCATTCCACTAAACAAAGCACAG
TTTAATCAGCAAGAAACAAT

Product: fucose permease

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: 6-deoxy-L-galactose permease; L-fucose permease [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MIKNNTIQGSDGYLDKTPVFQFILLSCLFPLWGCAAALNDILITQFKSVFELSNFASALVQSAFYGGYFLIAIPASLVIK
KSSYKMAIMIGLSLYIFGCAAFFPASHMATYTMFLAAIFAIAVGLSFLETAANTYSSMLGPKSHATLRLNISQTFYPIGA
IAGILLGKYLIFQDGASLESQMATMSPDQIHAFRLEMLEYTLKPYKYIIFILIGVLALFMFTQYPKCKVAQQSGKKAPSI
GKTLKYLSTNNRFKKGIIAQFLYVGMQVAVWSFTIRLALEMSDINERAASNYMVYSFVCFFIGKFIANILMTKFSAEKVL
IVYSLIGMAFLAYVSLVHDFSAVYVAVGVSVLFGPCWATIYAGTLDTVDNEYTETAGAVIVMAIVGAAVVPAIQGLVADA
IGMQLSFLVNFICFGYVGYYFLGEMKNKNQSEKQTQLAEQTN

Sequences:

>Translated_442_residues
MIKNNTIQGSDGYLDKTPVFQFILLSCLFPLWGCAAALNDILITQFKSVFELSNFASALVQSAFYGGYFLIAIPASLVIK
KSSYKMAIMIGLSLYIFGCAAFFPASHMATYTMFLAAIFAIAVGLSFLETAANTYSSMLGPKSHATLRLNISQTFYPIGA
IAGILLGKYLIFQDGASLESQMATMSPDQIHAFRLEMLEYTLKPYKYIIFILIGVLALFMFTQYPKCKVAQQSGKKAPSI
GKTLKYLSTNNRFKKGIIAQFLYVGMQVAVWSFTIRLALEMSDINERAASNYMVYSFVCFFIGKFIANILMTKFSAEKVL
IVYSLIGMAFLAYVSLVHDFSAVYVAVGVSVLFGPCWATIYAGTLDTVDNEYTETAGAVIVMAIVGAAVVPAIQGLVADA
IGMQLSFLVNFICFGYVGYYFLGEMKNKNQSEKQTQLAEQTN
>Mature_442_residues
MIKNNTIQGSDGYLDKTPVFQFILLSCLFPLWGCAAALNDILITQFKSVFELSNFASALVQSAFYGGYFLIAIPASLVIK
KSSYKMAIMIGLSLYIFGCAAFFPASHMATYTMFLAAIFAIAVGLSFLETAANTYSSMLGPKSHATLRLNISQTFYPIGA
IAGILLGKYLIFQDGASLESQMATMSPDQIHAFRLEMLEYTLKPYKYIIFILIGVLALFMFTQYPKCKVAQQSGKKAPSI
GKTLKYLSTNNRFKKGIIAQFLYVGMQVAVWSFTIRLALEMSDINERAASNYMVYSFVCFFIGKFIANILMTKFSAEKVL
IVYSLIGMAFLAYVSLVHDFSAVYVAVGVSVLFGPCWATIYAGTLDTVDNEYTETAGAVIVMAIVGAAVVPAIQGLVADA
IGMQLSFLVNFICFGYVGYYFLGEMKNKNQSEKQTQLAEQTN

Specific function: Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=415, Percent_Identity=37.3493975903614, Blast_Score=261, Evalue=8e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005275
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48609; Mature: 48609

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKNNTIQGSDGYLDKTPVFQFILLSCLFPLWGCAAALNDILITQFKSVFELSNFASALV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSAFYGGYFLIAIPASLVIKKSSYKMAIMIGLSLYIFGCAAFFPASHMATYTMFLAAIFA
HHHHHCCEEEEEECHHHHEECCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
IAVGLSFLETAANTYSSMLGPKSHATLRLNISQTFYPIGAIAGILLGKYLIFQDGASLES
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHEECCCCHHH
QMATMSPDQIHAFRLEMLEYTLKPYKYIIFILIGVLALFMFTQYPKCKVAQQSGKKAPSI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCH
GKTLKYLSTNNRFKKGIIAQFLYVGMQVAVWSFTIRLALEMSDINERAASNYMVYSFVCF
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHCCHHHHHHHHH
FIGKFIANILMTKFSAEKVLIVYSLIGMAFLAYVSLVHDFSAVYVAVGVSVLFGPCWATI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAGTLDTVDNEYTETAGAVIVMAIVGAAVVPAIQGLVADAIGMQLSFLVNFICFGYVGYY
HHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGEMKNKNQSEKQTQLAEQTN
HHHHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MIKNNTIQGSDGYLDKTPVFQFILLSCLFPLWGCAAALNDILITQFKSVFELSNFASALV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSAFYGGYFLIAIPASLVIKKSSYKMAIMIGLSLYIFGCAAFFPASHMATYTMFLAAIFA
HHHHHCCEEEEEECHHHHEECCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
IAVGLSFLETAANTYSSMLGPKSHATLRLNISQTFYPIGAIAGILLGKYLIFQDGASLES
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHEECCCCHHH
QMATMSPDQIHAFRLEMLEYTLKPYKYIIFILIGVLALFMFTQYPKCKVAQQSGKKAPSI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCH
GKTLKYLSTNNRFKKGIIAQFLYVGMQVAVWSFTIRLALEMSDINERAASNYMVYSFVCF
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHCCHHHHHHHHH
FIGKFIANILMTKFSAEKVLIVYSLIGMAFLAYVSLVHDFSAVYVAVGVSVLFGPCWATI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAGTLDTVDNEYTETAGAVIVMAIVGAAVVPAIQGLVADAIGMQLSFLVNFICFGYVGYY
HHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGEMKNKNQSEKQTQLAEQTN
HHHHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2664711; 9278503; 2553671; 8052131; 2829831; 7783647 [H]