Click here to switch to the map view.

The map label for this gene is ompR

Identifier: 37678420

GI number: 37678420

Start: 243345

End: 244076

Strand: Direct

Name: ompR

Synonym: VV0236

Alternate gene names: 37678420

Gene position: 243345-244076 (Clockwise)

Preceding gene: 161486671

Following gene: 37678421

Centisome position: 7.25

GC content: 50.0

Gene sequence:

>732_bases
GTGGACGGACACATGCAAGAGAATTTTAAAATTTTAGTGGTTGATGATGATGCTCGCTTGCGTGCGTTGTTGGAGCGTTA
TCTGTCAGAGCAAGGTTTCCAAGTGCGCAGTGTTGCCAATGGGGAACAGATGGATCGCCTATTGACCCGTGAAAACTTCC
ACTTAATGGTGTTGGATTTAATGCTTCCTGGTGAAGATGGTCTTTCGATCTGTCGTCGTCTGCGTAATGCCAACAACATG
TTGCCTATCCTGATGCTAACGGCAAAAGGGGATGAAGTTGACCGCATCGTGGGTTTAGAAGTGGGTGCTGATGACTACCT
GCCAAAACCATTCAACCCGCGTGAGCTGTTAGCACGTATTAAAGCGGTGCTGCGTCGTCAAACCATCGAGCTACCAGGCG
CGCCAAGCGCGGAAGAGAAAATTGTCGAGTTTGGTGAGTTTCGTCTGAACTTGGGCACGCGTGAAATGTTCCGTGGTGAT
GAGCCGATGCCACTCACCTCGGGTGAATTTGCGGTACTGAAATCGCTAGTGACCAATGCGCGCGAACCGATGTCGCGCGA
CAAGTTGATGAACATGGCGCGCGGACGTGAATACTCCGCGATGGAACGTTCCATTGACGTACAAATTTCTCGCCTACGTC
GTATGTTGGAAGAGGACCCAAGCAAACCTCGCTACATCCAAACTGTATGGGGCTTAGGTTATGTGTTTGTTCCTGATGGC
AAACCAGCATAA

Upstream 100 bases:

>100_bases
ATCCGCTAAAAGTAATAAAGATTAACAATTCTTTGCGCCATAAATGGATAATCGGTGTTACATTTTACCGAACCAAATTT
GGTGGAAGCTTATGAAATAG

Downstream 100 bases:

>100_bases
TCTCACATGACGATTCTTCTACAATCCCTGGCTTTGACCAGGGATTGTTGTTTATTCTACCTTCGTACTCTACCTAGCTG
CCGAGGTCTTTGATGCGTTT

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MDGHMQENFKILVVDDDARLRALLERYLSEQGFQVRSVANGEQMDRLLTRENFHLMVLDLMLPGEDGLSICRRLRNANNM
LPILMLTAKGDEVDRIVGLEVGADDYLPKPFNPRELLARIKAVLRRQTIELPGAPSAEEKIVEFGEFRLNLGTREMFRGD
EPMPLTSGEFAVLKSLVTNAREPMSRDKLMNMARGREYSAMERSIDVQISRLRRMLEEDPSKPRYIQTVWGLGYVFVPDG
KPA

Sequences:

>Translated_243_residues
MDGHMQENFKILVVDDDARLRALLERYLSEQGFQVRSVANGEQMDRLLTRENFHLMVLDLMLPGEDGLSICRRLRNANNM
LPILMLTAKGDEVDRIVGLEVGADDYLPKPFNPRELLARIKAVLRRQTIELPGAPSAEEKIVEFGEFRLNLGTREMFRGD
EPMPLTSGEFAVLKSLVTNAREPMSRDKLMNMARGREYSAMERSIDVQISRLRRMLEEDPSKPRYIQTVWGLGYVFVPDG
KPA
>Mature_243_residues
MDGHMQENFKILVVDDDARLRALLERYLSEQGFQVRSVANGEQMDRLLTRENFHLMVLDLMLPGEDGLSICRRLRNANNM
LPILMLTAKGDEVDRIVGLEVGADDYLPKPFNPRELLARIKAVLRRQTIELPGAPSAEEKIVEFGEFRLNLGTREMFRGD
EPMPLTSGEFAVLKSLVTNAREPMSRDKLMNMARGREYSAMERSIDVQISRLRRMLEEDPSKPRYIQTVWGLGYVFVPDG
KPA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=239, Percent_Identity=84.5188284518828, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=37.5545851528384, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=36.3247863247863, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=36.9098712446352, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=37.3390557939914, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=34.1991341991342, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=39.3162393162393, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=36.4406779661017, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=36.7965367965368, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=34.061135371179, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=34.2105263157895, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=34.4827586206897, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=33.9285714285714, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=33.7719298245614, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=32.520325203252, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788550, Length=121, Percent_Identity=27.2727272727273, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27781; Mature: 27781

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGHMQENFKILVVDDDARLRALLERYLSEQGFQVRSVANGEQMDRLLTRENFHLMVLDL
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCEEEEEEE
MLPGEDGLSICRRLRNANNMLPILMLTAKGDEVDRIVGLEVGADDYLPKPFNPRELLARI
ECCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHH
KAVLRRQTIELPGAPSAEEKIVEFGEFRLNLGTREMFRGDEPMPLTSGEFAVLKSLVTNA
HHHHHHHHCCCCCCCCHHHHHHHHHHHEECCCCHHHHCCCCCCCCCCCHHHHHHHHHHHH
REPMSRDKLMNMARGREYSAMERSIDVQISRLRRMLEEDPSKPRYIQTVWGLGYVFVPDG
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEECCC
KPA
CCC
>Mature Secondary Structure
MDGHMQENFKILVVDDDARLRALLERYLSEQGFQVRSVANGEQMDRLLTRENFHLMVLDL
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCEEEEEEE
MLPGEDGLSICRRLRNANNMLPILMLTAKGDEVDRIVGLEVGADDYLPKPFNPRELLARI
ECCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHH
KAVLRRQTIELPGAPSAEEKIVEFGEFRLNLGTREMFRGDEPMPLTSGEFAVLKSLVTNA
HHHHHHHHCCCCCCCCHHHHHHHHHHHEECCCCHHHHCCCCCCCCCCCHHHHHHHHHHHH
REPMSRDKLMNMARGREYSAMERSIDVQISRLRRMLEEDPSKPRYIQTVWGLGYVFVPDG
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEECCC
KPA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]